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Conditions: Panic Disorder
Interventions: Not listed
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 18 Years to 60 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Obsessive Compulsive Disorder (OCD), Anxiety Disorder of Childhood or Adolescence, Social Anxiety Disorder of Childhood, Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder, Panic Disorder, Panic Attacks, Panic Disorder (With or Without Agoraphobia), Phobia, Specific
Interventions: Parent Coached Exposure Therapy, Family Based, Internet-Based Cognitive Behavioral Therapy; Behavioral
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 7 Years to 17 Years
Enrollment: 174 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Social Anxiety Disorder, Panic Disorder
Interventions: Inhibitory Learning-Based Exposure, Habituation-Based Exposure; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 65 Years
Enrollment: 89 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Major Depression
Interventions: sertraline hydrochloride; Drug
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2007
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Panic Disorder
Interventions: Intensive Panic Control Treatment (IPCT); Behavioral
Lead sponsor: Michael E. DeBakey VA Medical Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder, Obsessive Compulsive Disorder (OCD)
Interventions: Not listed
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 1,431 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence, Generalized Anxiety Disorder, Separation Anxiety, Panic Disorder, Panic Disorder With Agoraphobia, Panic Attacks
Interventions: Family Based, Internet-Based Cognitive Behavioral Therapy, Bibliotherapy, low therapist contact SPACE, Relaxation and Mentorship; Behavioral · Other
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 7 Years to 13 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Acute Coronary Syndrome, Heart Failure, Depression, Generalized Anxiety Disorder, Panic Disorder
Interventions: Collaborative Care; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years and older
Enrollment: 290 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 3
States / cities: Boston, Massachusetts • Salem, Massachusetts

Conditions: Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Post Traumatic Stress Disorder, Agoraphobia, Simple Phobia
Interventions: Mindfulness-Based Stress Reduction, Waitlist; Behavioral
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2022
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Panic Disorder
Interventions: Vortioxetine; Drug
Lead sponsor: Siyan Clinical Corporation; Other
Eligibility: 18 Years to 60 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Santa Rosa, California

Conditions: Anxiety Disorders, Generalized Anxiety Disorder, Social Anxiety Disorder, Panic Disorder, Agoraphobia, Major Depressive Disorder, Persistent Depressive Disorder (Dysthymia)
Interventions: Mindful Self-Compassion; Behavioral
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Panic Disorder
Interventions: Paroxetine, Clozapine; Drug
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: Not listed
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Generalized Anxiety Disorder, Panic Disorder, Social Anxiety
Interventions: Low Intensity Exercise Intervention, High Intensity Intervention; Behavioral
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 65 Years
Enrollment: 9 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Panic Disorder
Interventions: Clonazepam, Sertraline, Cognitive behavioral therapy; Drug · Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2007
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Anxiety, Social Anxiety Disorder, Panic Disorder, Generalized Anxiety Disorder
Interventions: Functional magnetic resonance imaging (fMRI) with Veritable-NF, fMRI with Sham-NF; Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 24 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Bipolar Disorder
Interventions: Not listed
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 18 Years to 100 Years
Enrollment: 4,185 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 1994
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Panic Disorder
Interventions: Not listed
Lead sponsor: University of Arkansas, Fayetteville; Other
Eligibility: 12 Years to 17 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Fayetteville, Arkansas

Conditions: Post Traumatic Stress Disorder, Anxiety Disorders, Panic Disorder, Social Phobia, Phobia
Interventions: Novelty facilitated extinction, Standard Extinction; Behavioral
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years to 50 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Health Behavior, Quality of Life, Aging
Interventions: Not listed
Lead sponsor: University of Central Florida; Other
Eligibility: 18 Years to 110 Years
Enrollment: 10,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2025
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Panic Disorder, Healthy
Interventions: [18F] SPA-RQ; Drug
Lead sponsor: National Institute of Mental Health (NIMH); NIH
Eligibility: 18 Years to 65 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2008
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Panic Disorder, Generalized Anxiety Disorder, Social Anxiety Disorder
Interventions: Transdiagnostic Treatment (F-SET); Behavioral
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Social Anxiety Disorder, Specific Phobia, Separation Anxiety Disorder, Panic Disorder, Agoraphobia, Obsessive-Compulsive Disorder
Interventions: McLean Anxiety Mastery Program; Behavioral
Lead sponsor: Mclean Hospital; Other
Eligibility: 6 Years to 19 Years
Enrollment: 559 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2024
U.S. locations: 1
States / cities: Cambridge, Massachusetts

Conditions: Anxiety Disorders, Social Anxiety Disorder, Social Phobia, Generalized Anxiety Disorder, Separation Anxiety Disorder, Specific Phobia, Phobia, Agoraphobia, Panic Disorder, Panic Attack, Anxiety
Interventions: Cognitive Behavioral Therapy, Relaxation Therapy; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 7 Years to 17 Years
Enrollment: 207 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Generalized Anxiety Disorder, Agoraphobia, Panic Disorder, PostTraumatic Stress Disorder, Social Anxiety Disorder, Major Depressive Disorder
Interventions: Floating, Comparison; Behavioral
Lead sponsor: Laureate Institute for Brain Research, Inc.; Other
Eligibility: 18 Years to 55 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Tulsa, Oklahoma

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Neurobiological Mechanisms in Panic Disorder

Comparative Effectiveness of Internet-based Versus Parent-Coached Cognitive-Behavioral Therapy For Children and Adolescents With Anxiety and OCD

Optimizing Exposure Therapy for Anxiety Disorders

Pharmacotherapy in Depression With Panic Spectrum

Improving Access To Services to Community Based Outpatient Clinics (CBOC's)

Evaluating the Effects of Stress in Pregnancy

Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder

Pragmatic Collaborative Care for Cardiac Inpatients With Depression or Anxiety

Effect of Mindfulness Meditation on Physiological Response to Unpredictable Stimuli

A 10-Week, Open-Label, Flexible Dose Adaptive Study Evaluating the Efficacy of Vortioxetine in Subjects With Panic Disorder

Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method

Evaluation of Clonazepam and Paroxetine for Panic Disorder With Depression

Walking or High Intensity Exercise for Anxiety

Therapies for Treatment-Resistant Panic Disorder Symptoms

Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4

Evaluation of the Genetics of Bipolar Disorder

Evaluating the Relationship Between Tobacco Use, Anxiety Sensitivity, and Panic in Adolescents

Neuroimaging of Pavlovian Fear Conditioning Processes in Patients With Pathological Anxiety

The Lake Nona Life Project

Evaluation of Substance P Neurotransmission in Panic Disorder by PET Imaging of NK1 Receptors With [18F]SPA-RQ

False Safety Behavior Elimination Therapy: A Randomized Study of a Brief Individual Transdiagnostic Treatment for Anxiety Disorders

Building an Outcomes Assessment Infrastructure to Assess Anxiety Treatment

Dimensional Brain Behavior Predictors of CBT Outcomes in Pediatric Anxiety

Examining the Effects of Reduced Environmental Stimulation on Anxiety