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ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:00 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 69 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Pediatric Critical Illness Clear all

Conditions: COVID19, Coronavirus Infection, Coronavirus, Virus Diseases, RNA Virus Infections
Interventions: Convalescent Plasma; Biological
Lead sponsor: West Virginia University; Other
Eligibility: 31 Days and older
Enrollment: 117 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Acute Kidney Injury, Acute Kidney Injury Due to Sepsis
Interventions: QUELIMMUNE (SCD-PED); Device
Lead sponsor: SeaStar Medical; Industry
Eligibility: Up to 22 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 15
States / cities: Birmingham, Alabama • Palo Alto, California • San Francisco, California + 11 more

Conditions: Stroke, Diabetic Ketoacidosis, Increased Intracranial Pressures, Altered Mental Status
Interventions: NIRS; Device
Lead sponsor: Arkansas Children's Hospital Research Institute; Other
Eligibility: 1 Day to 21 Years
Enrollment: 299 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Respiratory Failure
Interventions: Midazolam, Normal saline, Fentanyl; Drug
Lead sponsor: Javier Gelvez, MD; Other
Eligibility: Up to 18 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Fort Worth, Texas

Conditions: Tracheostomy, Endotracheal Tube, Ventilator Associated Pneumonia, Tracheitis, Microbial Colonization, Pediatric Infectious Disease, Pediatrics
Interventions: Suctioning of artificial airway; Diagnostic Test
Lead sponsor: Northwell Health; Other
Eligibility: 0 Years to 18 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Queens, New York

Conditions: Sepsis, Hyperglycemia, Critical Illness
Interventions: Not listed
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 5 Years to 19 Years
Enrollment: 19 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Circadian Dysrhythmia, Sleep Disturbance, Critical Illness, Children, Only
Interventions: Daytime light exposure, Daytime restricted feeding; Other
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 3 Years to 6 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Pediatric Critical Illness
Interventions: No intervention; Other
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 1 Month to 18 Years
Enrollment: 1,944 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Critical Illness, Pediatrics, General Surgery, Fluid Therapy, Wounds and Injuries
Interventions: Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume, Platelets volume; Other
Lead sponsor: Columbia University; Other
Eligibility: 6 Months to 15 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2027
U.S. locations: 4
States / cities: Buffalo, New York • New York, New York • Rochester, New York + 1 more

Conditions: Pediatric, Critical Illness, Consent
Interventions: Biobank Video, Non-Video; Other
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Critical Illness
Interventions: Zinc sulfate; Drug
Lead sponsor: UCSF Benioff Children's Hospital Oakland; Other
Eligibility: 30 Days to 10 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2014
U.S. locations: 1
States / cities: Oakland, California

Conditions: Critical Illness, Pediatric Critical Illness, Respiratory Failure, Traumatic Brain Injury, Cardiac Arrest
Interventions: Transcranial Doppler; Device
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 1 Day to 17 Years
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Eye Injuries, Critically Ill
Interventions: plastic wrap over eye & lubrication applied q6 hrs; Procedure
Lead sponsor: Ann & Robert H Lurie Children's Hospital of Chicago; Other
Eligibility: 2 Weeks to 17 Years
Enrollment: 207 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 2
States / cities: Chicago, Illinois • Boston, Massachusetts

Conditions: Critical Illness
Interventions: Lorazepam, Midazolam, Lorazepam CI; Drug
Lead sponsor: The Emmes Company, LLC; Industry
Eligibility: 1 Day to 18 Years
Enrollment: 179 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Family Members of: Newborns Extremely Premature, Family Members of: New Pediatric Oncology Patients, Family Members of: Critical Congenital Heart Defect Patients, Family Members of: Children Severe Neurological Impairment
Interventions: Not listed
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: Not listed
Enrollment: 161,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Sepsis, Shock
Interventions: Tissue oxygenation monitoring; Device
Lead sponsor: University of Michigan; Other
Eligibility: 30 Days to 18 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Pediatric Acute Respiratory Distress Syndrome (PARDS), Pediatric Respiratory Diseases, Lung Compliance
Interventions: Not listed
Lead sponsor: Northwell Health; Other
Eligibility: 0 Days to 18 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: New Hyde Park, New York

Conditions: Children in the Pediatric Intensive Care Unit or General Pediatric Care Unit Requiring a Central Venous Catheter
Interventions: Cook Spectrum Pediatric Central Venous Catheter Anti-microbial Impregnated Polyurethane and Arrow Pediatric Central Venous Catheter; Device
Lead sponsor: Corewell Health West; Other
Eligibility: Up to 18 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2005
U.S. locations: 1
States / cities: Grand Rapids, Michigan

Conditions: Emergencies, Cardiopulmonary Arrest, Acute Respiratory Failure, Status Epilepticus
Interventions: Video teleconsultation, Audio support; Other
Lead sponsor: Boston Medical Center; Other
Eligibility: 21 Years and older
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 9
States / cities: Los Angeles, California • Aurora, Colorado • New Haven, Connecticut + 6 more

Conditions: ICU Length of Stay
Interventions: Primary intensivist and nurses; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: Not listed
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Anemia
Interventions: Pediatric phlebotomy tubes, Adult phlebotomy tubes; Device
Lead sponsor: The University of Texas Health Science Center, Houston; Other
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Critical Illness, Hypoxia, Brain
Interventions: Music therapy; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 2 Months to 17 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Systemic Inflammatory Response Syndrome (SIRS), Sepsis, Severe Sepsis, Septic Shock
Interventions: Severe Sepsis Management Bundle; Other
Lead sponsor: University of Tennessee; Other
Eligibility: 1 Month to 18 Years
Enrollment: 30,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Critical Illness, Dysbiosis, Pediatric ALL
Interventions: Nourish, Pediasure; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 1 Year to 17 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Search by objective public record fields.

Convalescent Plasma Collection and Treatment in Pediatrics and Adults

QUELIMMUNE (SCD-PED) PediAtric SurVeillance REgistry

Descriptive Analysis of Near Infrared Spectroscopy in Critically Ill and Injured Pediatric and Neonatal Patients

Cycling of Sedative Infusions in Critically Ill Pediatric Patients

Airway Microbiome Changes After Artificial Airway Exchange in Critically-ill Pediatric Patients.

Gluconeogenesis Rates and Its Precursors in Pediatric Sepsis

PICU-related Sleep and Circadian Dysregulation Pilot Study

Pediatric International Nutrition Study 2018

Effect of Giving Reduced Fluid in Children After Trauma

Examining Health Literacy in Biorepository Consents

Safety and Dose Escalation Study of Zinc Supplementation in Critically Ill Children

Brain Blood Flow and Cerebral Autoregulation Monitoring in Critically Ill Children

Does the Use of a Moisture Chamber Decrease the Incidence of Corneal Abrasions in Critically Ill Pediatric Patients?

Lorazepam Sedation for Critically Ill Children

Impact of Serious Pediatric Illness on Parent and Sibling Health

Noninvasive Assessment of Tissue Perfusion Status in Critically Ill Pediatric Patients

IPV and Lung Compliance in Invasively Ventilated Children

Study of the Use of Coated Venous Catheters in the Critically Ill Child

Simulation Trial of Telemedical Support for Paramedics

Primary Intensivists and Primary Nurses to Decrease Pediatric ICU Length of Stay

Use of Pediatric Size Phlebotomy Tubes in Adult Critically Ill Patients to Reduce Red Blood Cell Transfusions

Feasibility of a Music Therapy Intervention to Decrease Stress During Pediatric Critical Care

Electronic Application of a Severe Sepsis Screening Tool and Management Bundle

Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children