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ClinicalTrials.gov public records Last synced Nov 14, 2026, 10:16 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 69 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Pediatric Critical Illness Clear all

Conditions: Sepsis, Systemic Inflammatory Response Syndrome
Interventions: Automated Pulse Pressure Variation; Device
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: Up to 17 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Critical Illness
Interventions: Not listed
Lead sponsor: Children's Healthcare of Atlanta; Other
Eligibility: 1 Month to 18 Years
Enrollment: 212 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Traumatic Brain Injury, Critical Illness, Sleep
Interventions: melatonin, placebo; Drug · Other
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 6 Years to 18 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Hypoglycemia Hyperglycemia
Interventions: Not listed
Lead sponsor: Indiana University; Other
Eligibility: 1 Day to 21 Years
Enrollment: 206 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 3
States / cities: Atlanta, Georgia • Macon, Georgia

Conditions: Critical Illness
Interventions: Not listed
Lead sponsor: Children's Healthcare of Atlanta; Other
Eligibility: 5 Months and older
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Critical Illness, Sedation Complication, Delirium
Interventions: Dexmedetomidine Hydrochloride - Cycling, Fentanyl - PICU Standard, Dexmedetomidine Hydrochloride - PICU Standard; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 12 Years to 17 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Pediatric, Critical Illness, Sleep Disturbance
Interventions: Sleep education; Behavioral
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 6 Years to 18 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Critically Ill, Hyperglycemia
Interventions: glucose control with computer generated recommendations; Procedure
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 1 Month and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2018
U.S. locations: 10
States / cities: Madera, California • Saint Paul, Minnesota • Lebanon, New Hampshire + 5 more

Conditions: Community Acquired Pneumonia
Interventions: Not listed
Lead sponsor: Loma Linda University; Other
Eligibility: 1 Day to 21 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Loma Linda, California

Conditions: Sepsis, Bacteremia
Interventions: Multicenter Quality Improvement program; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: Not listed
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 5
States / cities: St Louis, Missouri • Cleveland, Ohio • Portland, Oregon + 2 more

Conditions: Renal Angina, Acute Kidney Injury
Interventions: Not listed
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Not listed
Enrollment: 184 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Venous Thromboembolism (VTE)
Interventions: Enoxaparin; Drug
Lead sponsor: Johns Hopkins All Children's Hospital; Other
Eligibility: 12 Years to 18 Years
Enrollment: 802 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2027 – 2035
U.S. locations: 1
States / cities: St. Petersburg, Florida

Conditions: Metabolism and Nutrition Disorder
Interventions: PICS in critically ill pediatric population; Other
Lead sponsor: Indiana University; Other
Eligibility: Up to 18 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Sepsis, Critical Illness
Interventions: Observational; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 1 Month to 19 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Child, Intensive Care Unit Acquired Weakness, Critical Illness, Hospital Acquired Pressure Ulcer
Interventions: PICU Up!; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: Not listed
Enrollment: 1,470 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 11
States / cities: Madera, California • Orlando, Florida • Louisville, Kentucky + 8 more

Conditions: Critically Ill Children
Interventions: Peptide-based enteral formula, Retrospective review of enteral tube feeding formula; Other
Lead sponsor: Société des Produits Nestlé (SPN); Industry
Eligibility: 1 Year to 13 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 2
States / cities: Chicago, Illinois • Memphis, Tennessee

Conditions: Acute Kidney Injury, Renal Replacement Therapy, Pediatric Intensive Care Units
Interventions: Not listed
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 3 Months to 25 Years
Enrollment: 420 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2029
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Sepsis, Critical Illness
Interventions: Observational; Other
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 1 Month to 19 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Acute Kidney Injury, Acute Kidney Injury Due to Sepsis, Neonatal Sepsis
Interventions: Renal Angina Index (RAI); Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: Up to 25 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Gastroparesis, Gastrointestinal Disorder, Functional, Critical Illness
Interventions: Not listed
Lead sponsor: Boston Children's Hospital; Other
Eligibility: 2 Years to 30 Years
Enrollment: 99 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Critically Ill, Hyperglycemia
Interventions: glucose control with computer generated recommendations; Procedure
Lead sponsor: Intermountain Health Care, Inc.; Other
Eligibility: 1 Month and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2018
U.S. locations: 11
States / cities: New Haven, Connecticut • Baltimore, Maryland • Boston, Massachusetts + 7 more

Conditions: Acute Kidney Injury, Fluid Overload
Interventions: Continuous Renal Replacement Therapy; Other
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 1 Year to 25 Years
Enrollment: 39 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Ventilator Associated Pneumonia, Tracheobronchitis
Interventions: Not listed
Lead sponsor: Johns Hopkins University; Other
Eligibility: Not listed
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 8
States / cities: Baltimore, Maryland • Boston, Massachusetts • Minneapolis, Minnesota + 5 more

Conditions: Critical Illness
Interventions: Continuity Care Intensivist Communication Training, Continuity Care Intensivist (CCI) Provider Program; Behavioral
Lead sponsor: Children's Hospital of Philadelphia; Other
Eligibility: Not listed
Enrollment: 276 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Search by objective public record fields.

PPV to Guide Fluid Management in the PICU

Ultrasound Guided Vascular Access in Pediatric Intensive Care Patients

Sleep Management And Recovery After Traumatic Brain Injury in Kids: Pilot Intervention of Melatonin

Pediatric Critical Illness Hyperglycemia and Glycemic Control Registry

Neuroendocrine Dysfunction in Critically Ill Pediatric Patients

Dexmedetomidine Cycling and Sleep in the Pediatric ICU

Sleep After Pediatric Critical Illness

Improving Blood Glucose Control With a Computerized Decision Support Tool: Phase 2

Clinical Pediatric Pneumonia Score in Critically Ill Children

Blood Culture Improvement Guidelines and Diagnostic Stewardship for Antibiotic Reduction in Critically Ill Children

Study of the Prediction of Acute Kidney Injury in Children Using Risk Stratification and Biomarkers

Collaborative Risk-stratified Investigation in Thrombosis-prone Inpatients With Critical Illness: Anticoagulation With LMWH in Teens for ThromboProphylaxis (CRITICAL-Teens-TP).

Prospective Evaluation of the Incidence of PICS

Methionine Metabolism in Parenterally Fed Pediatric Sepsis

Clinical Effectiveness of the "PICU Up!" Multifaceted Early Mobility Intervention for Critically Ill Children

Improvement Project To Optimizing Nutrition With Higher Protein and Calorie Pediatric Tube Feeding

Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric AKI

Methionine Metabolism in Enterally Fed Pediatric Sepsis

Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric and Neonatal AKI

Protease Activated Receptor-2 and Gastrointestinal Dysfunction in Critical Illness

Improving Blood Glucose Control With a Computerized Decision Support Tool: Phase 1

Use of Biomarkers to Optimize Fluid Dosing,CRRT Initiation and Discontinuation in Pediatric ICU Patients With AKI

A Multi-Center Diagnostic Stewardship Program to Improve Respiratory Culture Utilization in Critically Ill Children

Pediatric Continuity Care Intensivist