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ClinicalTrials.gov public records Last synced May 21, 2026, 11:00 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–13 of 13 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Perforated Eardrum Clear all
Completed No phase listed Observational
View directory record Official record
Conditions
Tympanic Membrane Perforation, Eardrum Perforation
Interventions
Biodesign Otologic Repair Graft
Device
Lead sponsor
Cook Research Incorporated
Industry
Eligibility
Not listed
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
4
States / cities
Indianapolis, Indiana • Cincinnati, Ohio • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced May 21, 2026, 11:00 PM EDT
Suspended Phase 1Phase 2 Interventional
View directory record Official record
Conditions
Chronic Tympanic Membrane Perforation
Interventions
Fibroblast Growth Factor 2, Saline control
Drug
Lead sponsor
D. Bradley Welling, MD, PhD
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 7, 2025 · Synced May 21, 2026, 11:00 PM EDT
Not listed Early Phase 1 Interventional
View directory record Official record
Conditions
Perforated Eardrum
Interventions
Isoflurane Inhalant Product, Sevoflurane inhalant product, Propofol injection, Remifentanil Injection
Drug
Lead sponsor
Our Lady of the Lake Hospital
Other
Eligibility
0 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced May 21, 2026, 11:00 PM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Tympanic Membrane Perforation
Interventions
FGF-2, Placebo
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced May 21, 2026, 11:00 PM EDT
Terminated No phase listed Observational
View directory record Official record
Conditions
Tympanic Membrane Perforation
Interventions
Eustachian tube function testing
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
3 Years to 16 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 8, 2018 · Synced May 21, 2026, 11:00 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Hearing Loss, Conductive, Hearing Loss, Mixed Conductive-Sensorineural, Otosclerosis, Tympanic Membrane Perforation, Otitis Media With Effusion, Cholesteatoma
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 89 Years
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
2
States / cities
Portland, Oregon • Mountain Home, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced May 21, 2026, 11:00 PM EDT
Withdrawn Phase 4 Interventional
View directory record Official record
Conditions
Tympanic Membrane Perforation
Interventions
Biodesign Otologic graft, Autologous temporalis fascia
Biological · Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced May 21, 2026, 11:00 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Tympanic Membrane Perforation
Interventions
Perf-Fix Otologic Gel Patch
Device
Lead sponsor
Tympanogen
Industry
Eligibility
5 Years and older
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
7
States / cities
Los Angeles, California • Louisville, Kentucky • Mandeville, Louisiana + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced May 21, 2026, 11:00 PM EDT
Terminated Phase 1Phase 2 Interventional Results available
View directory record Official record
Conditions
Tympanic Membrane Perforation
Interventions
Platelet Rich Plasma
Biological
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced May 21, 2026, 11:00 PM EDT
Completed No phase listed Interventional Results available
View directory record Official record
Conditions
Tympanic Membrane Perforation
Interventions
Tympanoseal
Device
Lead sponsor
Grace Medical, Inc.
Industry
Eligibility
2 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced May 21, 2026, 11:00 PM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Tympanic Membrane Perforation
Interventions
FGF-2, Placebo
Drug · Other
Lead sponsor
D. Bradley Welling, MD, PhD
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Boston, Massachusetts • Lackland City, Texas
Source: ClinicalTrials.gov public record
Updated Dec 7, 2025 · Synced May 21, 2026, 11:00 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Tympanic Membrane Perforation
Interventions
Tympanoseal
Device
Lead sponsor
Grace Medical, Inc.
Industry
Eligibility
2 Years to 100 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Farmington Hills, Michigan • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced May 21, 2026, 11:00 PM EDT
Terminated Phase 1Phase 2 Interventional Results available
View directory record Official record
Conditions
Chronic Tympanic Membrane Perforation
Interventions
ASP0598, Placebo
Drug · Other
Lead sponsor
Astellas Pharma Global Development, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
10
States / cities
Palo Alto, California • Torrance, California • Boca Raton, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 24, 2024 · Synced May 21, 2026, 11:00 PM EDT