Clinical Trials Finder
Independent ClinicalTrials.gov directory
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced May 21, 2026, 10:57 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Periprosthetic Joint Infection Clear all
Enrolling by invitation No phase listed Observational
View directory record Official record
Conditions
Total Joint Arthroplasty, Periprosthetic Joint Infections
Interventions
Blood Draw or Saliva/Cheek Cell Sample:
Genetic
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 100 Years
Enrollment
150 participants
Timeline
2018 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced May 21, 2026, 10:57 PM EDT
Withdrawn Not applicable Interventional
View directory record Official record
Conditions
Periprosthetic Joint Infection, Antibiotic Suppression
Interventions
6 months of SAT, 12 months of SAT, Indefinite SAT
Drug
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced May 21, 2026, 10:57 PM EDT
Enrolling by invitation Not applicable Interventional
View directory record Official record
Conditions
Periprosthetic Joint Infection
Interventions
Single Debridement, Antibiotics and Implant Retention, Planned Double Debridement, Antibiotics and Implant Retention
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
490 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
2
States / cities
Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced May 21, 2026, 10:57 PM EDT
Terminated Not applicable Interventional
View directory record Official record
Conditions
Periprosthetic Joint Infection
Interventions
Sterile Water, 3.5% Betadine, 0.05% Chlorhexidine Gluconate
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced May 21, 2026, 10:57 PM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Prosthetic Joint Infection
Interventions
leukocyte esterase electrochemical assay
Diagnostic Test
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2020 · Synced May 21, 2026, 10:57 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
PJI
Interventions
Synovasure® Comprehensive Infection Panel
Diagnostic Test
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
810 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced May 21, 2026, 10:57 PM EDT
Enrolling by invitation Phase 4 Interventional
View directory record Official record
Conditions
Infections Joint Prosthetic, Overweight or Obesity, MSSA Colonization, MRSA, Chronic Kidney Diseases, Diabetes, Autoimmune Diseases, Inflammatory Disease, Tobacco Use
Interventions
Cephalexin, Doxycycline, Cefadroxil
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
4,618 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Iowa City, Iowa • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced May 21, 2026, 10:57 PM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Prosthetic-joint Infection
Interventions
Surgiphor Irrigation Solution, Sterile saline
Device
Lead sponsor
Center for Innovation and Research Organization
Network
Eligibility
18 Years and older
Enrollment
868 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
4
States / cities
Phoenix, Arizona • Baltimore, Maryland • Columbia, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2023 · Synced May 21, 2026, 10:57 PM EDT
Completed Phase 1 Interventional
View directory record Official record
Conditions
Joint Infection
Interventions
PLG0206
Drug
Lead sponsor
Peptilogics
Industry
Eligibility
18 Years to 79 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Palo Alto, California • Sarasota, Florida • Baltimore, Maryland + 8 more
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced May 21, 2026, 10:57 PM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Prosthetic-joint Infection
Interventions
Semi-quantitative electrochemical leukocyte esterse test strip, Roche Chemstrip
Diagnostic Test
Lead sponsor
Center for Innovation and Research Organization
Network
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
8
States / cities
Denver, Colorado • Weston, Florida • Louisville, Kentucky + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2024 · Synced May 21, 2026, 10:57 PM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Prosthetic Joint Infection
Interventions
VT-X7 Treatment System with Tobramycin Sulfate, Standard of Care, Two-stage exchange arthroplasty, VT-X7 Treatment System with Vancomycin Hydrochloride
Combination Product · Drug · Procedure
Lead sponsor
Osteal Therapeutics, Inc.
Industry
Eligibility
22 Years to 84 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
17
States / cities
Phoenix, Arizona • Torrance, California • Washington D.C., District of Columbia + 13 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced May 21, 2026, 10:57 PM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Prosthetic-joint Infection
Interventions
VT-X7 Treatment System, Two-stage exchange arthroplasty, SOC Antibiotics, Experimental Antibiotics
Combination Product · Procedure · Drug
Lead sponsor
Osteal Therapeutics, Inc.
Industry
Eligibility
22 Years to 84 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
19
States / cities
Phoenix, Arizona • Los Angeles, California • Sarasota, Florida + 15 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced May 21, 2026, 10:57 PM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Prosthetic Joint Infection
Interventions
No intervention: sample collection study
Other
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 11, 2017 · Synced May 21, 2026, 10:57 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Infection, Bacterial
Interventions
Using surgical diathermy to make skin incision, Using scalpel blade to make skin incision
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older · Male only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced May 21, 2026, 10:57 PM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Surgical Site Infection
Interventions
One-stage exchange joint replacement surgery, Two-stage exchange joint replacement surgery
Procedure
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
5
States / cities
Chicago, Illinois • New York, New York • Charlotte, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2025 · Synced May 21, 2026, 10:57 PM EDT
Recruiting Phase 4 Interventional
View directory record Official record
Conditions
Aseptic Loosening of Prosthetic Joint, Instability of Prosthetic Joint, Reimplantation for Periprosthetic Joint Infection, Femoral Revision Indicated, Tibial Component Revision
Interventions
Constrained Condylar bearing, posterior stabilized bearing
Device
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2038
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced May 21, 2026, 10:57 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Periprosthetic Joint Infection
Interventions
REMEDY Spectrum IM Spacer Nail
Combination Product
Lead sponsor
OsteoRemedies, LLC
Industry
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
3
States / cities
Lansing, Michigan • Charlotte, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced May 21, 2026, 10:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Arthroplasty Shoulder, Periprosthetic Joint Infection
Interventions
Chlorhexidine Gluconate
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 89 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 4, 2024 · Synced May 21, 2026, 10:57 PM EDT
Terminated Not applicable Interventional Results available
View directory record Official record
Conditions
Prosthetic Joint Infection of the Knee
Interventions
Static Antibiotic Spacer Surgical Implant, Articulating Antibiotic Spacer Surgical Implant
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 14, 2019 · Synced May 21, 2026, 10:57 PM EDT
Recruiting Phase 2Phase 3 Interventional
View directory record Official record
Conditions
Prosthetic-joint Infection
Interventions
PLG0206, Placebo
Drug
Lead sponsor
Peptilogics
Industry
Eligibility
18 Years to 80 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
9
States / cities
Sarasota, Florida • Tamarac, Florida • Baltimore, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced May 21, 2026, 10:57 PM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Prosthetic-joint Infection, Knee Infection, Arthroplasty Complications, Joint Infection, Arthroplasty, Replacement, Knee
Interventions
All-cement articulating spacer, Durable, real-component articulating spacer, Rigid Spacer
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced May 21, 2026, 10:57 PM EDT
Not yet recruiting Phase 2 Interventional
View directory record Official record
Conditions
Periprosthetic Joint Infection (PJI)
Interventions
Ultrasound-triggered microbubble destruction with antibiotics
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced May 21, 2026, 10:57 PM EDT
Temporarily Not Available No phase listed Expanded access
View directory record Official record
Conditions
Prosthetic-joint Infection
Interventions
VT-X7 Treatment System
Combination Product
Lead sponsor
Osteal Therapeutics, Inc.
Industry
Eligibility
22 Years to 84 Years
U.S. locations
14
States / cities
Phoenix, Arizona • Los Angeles, California • Grand Junction, Colorado + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced May 21, 2026, 10:57 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Joint Infection
Interventions
Bactrim, Cefadroxil, Doxycycline Hcl, Clindamycin
Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
308 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced May 21, 2026, 10:57 PM EDT