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Showing 1–24 of 123 matching trials from the live ClinicalTrials.gov search.
Recruiting No phase listed Observational Accepts healthy volunteers

Regional Phenotyping of CF and Non-CF Bronchiectasis

NCT04793867
Conditions
Cystic Fibrosis, Non-CF Bronchiectasis
Interventions
Xenon
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Fatigue, Cancer, CFS, ME/CFS, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Lupus, Systemic Lupus Erthematosus, Sjogrens
Interventions
Not listed
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 120 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Sleep Apnea
Interventions
Dextromethorphan, Caffeine
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
4 Years to 16 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
2
States / cities
Louisville, Kentucky • Richmond, Virginia
Conditions
COPD, Pulmonary Hypertension, Right Ventricular Dysfunction, Exercise, Exercise Training
Interventions
Exercise
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
40 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Cystic Fibrosis, Asthma, Severe Persistent Asthma, Healthy
Interventions
Glycine Buffer
Drug
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 50 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2025
U.S. locations
2
States / cities
Indianapolis, Indiana • Cleveland, Ohio
Conditions
Sickle Cell Disease, Asthma
Interventions
Not listed
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
6 Years to 20 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
3
States / cities
Wilmington, Delaware • Jacksonville, Florida • Orlando, Florida
Active, not recruiting Not applicable Interventional

DISE: Phenotyping Obstruction Patterns

NCT05050383
Conditions
Obstructive Sleep Apnea
Interventions
Pharyngeal Manometry
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
HIV Infections
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
14 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
46
States / cities
Birmingham, Alabama • Los Angeles, California • Menlo Park, California + 27 more
Conditions
Protein Metabolism
Interventions
Whey Protein Isolate 90%, Soy Protein Isolate (90% Protein), Organic Pea Protein Isolate, Placebo (Water)
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
50 Years to 95 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
College Station, Texas
Completed No phase listed Observational

Repository for Inherited Eye Diseases

NCT00378742
Conditions
Retinitis Pigmentosa, Inherited Ophthalmic Diseases
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
1 Day to 100 Years
Enrollment
6,618 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Alzheimer Disease, Down Syndrome, Mild Cognitive Impairment
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Completed No phase listed Observational Accepts healthy volunteers

Magnetic Resonance Imaging (MRI) Muscle Phenotyping in Mitochondrial Disease

NCT02154711
Conditions
Mitochondrial Disease
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Mobile Behavioral Activation Program With Wearable Sensors and Secure Activity Verification

NCT07382804
Conditions
Health Behavior, Behavioral Activation, Sedentary Behavior
Interventions
Behavioral: Mobile Behavioral Activation App, Mobile App + Wearable Activity Sensor, Mobile App + Wearable Sensor + Secure Activity Verification Layer
Behavioral
Lead sponsor
Truway Health, Inc.
Industry
Eligibility
18 Years and older
Enrollment
227,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2099
U.S. locations
1
States / cities
New York, New York
Enrolling by invitation No phase listed Observational

CrCest Study in Primary Mitochondrial Disease

NCT04734626
Conditions
Mitochondrial Diseases
Interventions
Creatine Chemical Exchange Saturation Transfer (CrCEST) Imaging Sequence
Diagnostic Test
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
7 Years to 75 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Brown Adipose Tissue (BAT) Physiology, Phenotyping, Brown Adipocytes
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 90 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
IC - Interstitial Cystitis
Interventions
Ferumoxytol, Gadobutrol
Diagnostic Test
Lead sponsor
Christopher J Chermansky, MD
Other
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Aging, Facial Aging
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Chronic Low Back Pain
Interventions
Epidural electrical spinal cord stimulator
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Sleep Apnea
Interventions
PAP
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 80 Years
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

GSNOR Phenotyping/GSNO Challenge in Severe Asthma

NCT03926741
Conditions
Asthma
Interventions
GSNO Challenge
Drug
Lead sponsor
James Reynolds
Other
Eligibility
18 Years to 50 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Indianapolis, Indiana • Cleveland, Ohio
Conditions
Bipolar Disorder
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Medication Adherence
Interventions
The PATTERN Intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
65 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Chicago, Illinois
Withdrawn No phase listed Observational Accepts healthy volunteers

Phenotyping Acute Pain for Discovery Research and Directed Therapeutics

NCT02322996
Conditions
Post op Pain
Interventions
questionnaires
Other
Lead sponsor
East Carolina University
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Greenville, North Carolina
Conditions
Chronic Rejection of Lung Transplant
Interventions
Lung transplant recipient without MRI imaging, Lung transplant recipient with MRI imaging
Diagnostic Test · Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 85 Years
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2038
U.S. locations
1
States / cities
Charlottesville, Virginia