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ClinicalTrials.gov public records Last synced Sep 6, 2026, 10:41 PM EDT

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Showing 1–18 of 18 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Photodamage Clear all
Completed Not applicable Interventional

Comparison of the RevLite Electro-optic Q-Switched Neodymium-doped Yttrium Aluminium Garnet (EO QS Nd:YAG) Laser to a Fractionated Laser System

NCT00955461
View directory record Official record
Conditions
Photodamage, Irregular Pigmentation, Acne Scars
Interventions
RevLite laser treatment, Fractionated Laser treatment
Procedure
Lead sponsor
ConBio, a Cynosure Company
Industry
Eligibility
25 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 27, 2012 · Synced Sep 6, 2026, 10:41 PM EDT
Completed Phase 3 Interventional Results available

Adapalene Gel 0.3% Versus Tretinoin 0.05% Emollient Cream for Treatment of Photodamage

NCT00647556
View directory record Official record
Conditions
Photoaging
Interventions
adapalene gel, 0.3%, tretinoin 0.05% emollient cream
Drug
Lead sponsor
Galderma R&D
Industry
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 31, 2022 · Synced Sep 6, 2026, 10:41 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Altreno for Chest Rejuvenation

NCT04096742
View directory record Official record
Conditions
Photodamaged Skin, Photoaging
Interventions
tretinoin 0.05% lotion (Altreno), Vehicle
Drug · Other
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2021 · Synced Sep 6, 2026, 10:41 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluating the Safety and Effectiveness of the Tixel Fractional System in the Treatment of Photodamage at Low Settings

NCT05182502
View directory record Official record
Conditions
Wrinkle
Interventions
Tixel
Device
Lead sponsor
Eric Bernstein, MD
Other
Eligibility
25 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Sep 6, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Single Band vs. Dual Band Pulsed Light Technology for the Treatment of Photodamage - A Split Face Comparison Study

NCT04519736
View directory record Official record
Conditions
Photodamage
Interventions
Single Band vs. Dual Band Pulsed Light Technology for the Treatment of Photodamage
Device
Lead sponsor
Alma Lasers Inc.
Industry
Eligibility
35 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Sep 6, 2026, 10:41 PM EDT
Terminated Not applicable Interventional Results available

Treatment of Field Cancerization for Reduction in Tumor Burden - A Prospective Study

NCT02150863
View directory record Official record
Conditions
Extensive Photodamage, Actinic Keratosis, History of Numerous Skin Cancers
Interventions
Ultrapulse Carbon Dioxide Laser, Cellutome epidermal harvesting system
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 17, 2019 · Synced Sep 6, 2026, 10:41 PM EDT
Completed Phase 2 Interventional Results available

Comparison of Retinol 1.0% and Tretinoin 0.02% in the Treatment of Moderate to Severe Photodamage and Wrinkles

NCT01283464
View directory record Official record
Conditions
Photodamaged Skin, Wrinkles
Interventions
Retinol, Tretinoin
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
35 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 3, 2016 · Synced Sep 6, 2026, 10:41 PM EDT
Not yet recruiting Not applicable Interventional

Evaluation of the Efficacy and Tolerability of the LED Mask With or Without the Serum Formula on the Signs of Facial Photodamage .

NCT07661004
View directory record Official record
Conditions
Photodamage of the Face, Anti Aging
Interventions
MASK LED, LED MASK AND COSMETIC FORMULA
Device · Combination Product
Lead sponsor
L'Oreal
Industry
Eligibility
35 Years to 60 Years · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 6, 2026, 10:41 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Activation of Ameluz With BBL HEROic for the Treatment of Actinic Keratoses and Photodamage

NCT07053852
View directory record Official record
Conditions
Actinic Keratoses, Photodamage
Interventions
Ameluz, Sciton HEROic
Drug · Device
Lead sponsor
Sherrif Ibrahim
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Victor, New York
Source: ClinicalTrials.gov public record
Updated Jan 1, 2026 · Synced Sep 6, 2026, 10:41 PM EDT
Completed Not applicable Interventional

Study to Evaluate Efficacy and Tolerability of Two Topical Regimens in Subjects With Moderate to Severe Facial Photodamage Who Have Received Cosmetic Injections

NCT03559972
View directory record Official record
Conditions
Facial Photodamage
Interventions
on-label facial injection
Other
Lead sponsor
Allergan
Industry
Eligibility
30 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
2
States / cities
San Diego, California • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Sep 6, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Laser 360iQ: Optimal Light-laser Combination Therapy

NCT04519723
View directory record Official record
Conditions
Photodamage
Interventions
Assess the safety and efficacy of light-laser therapy using the Harmony XL and Dye-VL (500-600nm), Q-Switched 1064nm, Er:YAG 2940nm modules in combination .
Device
Lead sponsor
Alma Lasers Inc.
Industry
Eligibility
35 Years to 60 Years · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Sep 6, 2026, 10:41 PM EDT
Completed Phase 2 Interventional

The Role of Topically Dissolved Oxygen (TDO) to Ameliorate Signs of Photodamage

NCT00991198
View directory record Official record
Conditions
Rosacea, Acne Vulgaris, Atopic Dermatitis, Seborrheic Dermatitis
Interventions
Topical oxygen, placebo
Drug
Lead sponsor
Aria Aesthetics Inc.
Industry
Eligibility
25 Years to 60 Years · Female only
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 7, 2011 · Synced Sep 6, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study to Assess the Cosmetic Changes in the Facial Skin After Use of a Topical Retinoid Product in Participants With Moderate to Severe Photodamage

NCT03302559
View directory record Official record
Conditions
Skin Care
Interventions
Retinol Complex 0.5, Facial cleanser, Moisturizing lotion, Sunscreen, Skin Imaging
Other · Device
Lead sponsor
Allergan
Industry
Eligibility
40 Years to 70 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2019 · Synced Sep 6, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Placebo-Controlled Study Assessing the Use of a Novel Exfoliative Serum With A Chemical Peel to Improve Photodamage in Adults

NCT05908825
View directory record Official record
Conditions
Photodamaged Skin
Interventions
Vitamin C with AHA Exfoliative Serum, Placebo serum
Drug
Lead sponsor
Austin Institute for Clinical Research
Network
Eligibility
30 Years to 65 Years · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pflugerville, Texas
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 6, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Prevention of Photodamage in Skin With Grapes

NCT02760160
View directory record Official record
Conditions
Non-melanoma Skin Cancer
Interventions
Reconstituted grape powder
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 99 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 7, 2019 · Synced Sep 6, 2026, 10:41 PM EDT
Not yet recruiting Phase 2Phase 3 Interventional

Skin Care Regimen for Improving Photoaging Signs on the Face

NCT06603857
View directory record Official record
Conditions
Improve Photoaging Signs
Interventions
CE Ferulic, Sham Comparator, 1927nm (Clear and Brilliant Perméa®)
Drug · Device
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
30 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 6, 2026, 10:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Twelve Week Clinical Study to Evaluate the Efficacy and Tolerability of a Sunscreen Moisturizer SPF 50+

NCT06148558
View directory record Official record
Conditions
Anti-aging, Photoaging
Interventions
Sunscreen Moisturizer, Gentle Cleansing Lotion, Facial Moisturizer
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 60 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Newtown Square, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 6, 2026, 10:41 PM EDT
Not yet recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Study Comparing Two Serums With Intense Pulsed Light for the Treatment of Moderate to Severe Photodamage and Crepiness on the Forearms

NCT07686198
View directory record Official record
Conditions
Photodamaged Skin
Interventions
Right Arm treated with Active Re-Q Pro-Longevity Serum and Intense Pulsed Light Therapy, Left Arm treated with vehicle serum and Intense Pulsed Light Therapy
Drug
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
50 Years to 80 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 6, 2026, 10:41 PM EDT