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ClinicalTrials.gov public records Last synced May 22, 2026, 2:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Polypharmacy Clear all
Completed Not applicable Interventional
View directory record Official record
Conditions
Polypharmacy, Deprescribing, Adverse Drug Reaction
Interventions
Deprescribing Intervention, Usual Care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
65 Years and older
Enrollment
419 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced May 22, 2026, 2:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Polypharmacy, Aging
Interventions
Hypothetical Scenario
Other
Lead sponsor
University of Michigan
Other
Eligibility
65 Years and older
Enrollment
10,184 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 12, 2022 · Synced May 22, 2026, 2:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Polypharmacy, Deprescribing, Telemedicine
Interventions
Medication management via televisit to home
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years and older
Enrollment
304 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
2
States / cities
Bedford, Massachusetts • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced May 22, 2026, 2:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Polypharmacy, Alzheimer's Disease and Related Dementias, Mild Cognitive Impairment
Interventions
Pharmacist-led deprescribing intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced May 22, 2026, 2:52 AM EDT
Active, not recruiting No phase listed Observational
View directory record Official record
Conditions
HIV-1-infection
Interventions
Bictegravir/Emtricitabine/Tenofovir Alafenamide 50 MG-200 MG-25 MG Oral Tablet [BIKTARVY]
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced May 22, 2026, 2:52 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Type 2 Diabetes Treated With Insulin, Hypoglycemia, Primary Health Care, Polypharmacy
Interventions
Conversation Aid, Attention Control Educational Handout
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
75 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
4
States / cities
San Francisco, California • San Leandro, California • Union City, California + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced May 22, 2026, 2:52 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Chronic Illness, Opioid Use, Palliative Care
Interventions
Clinical Decision Support System
Other
Lead sponsor
Hospice of Henderson County, Inc.
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
New York, New York • Flat Rock, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 16, 2021 · Synced May 22, 2026, 2:52 AM EDT
Active, not recruiting Not applicable Interventional Results available
View directory record Official record
Conditions
Nonadherence, Patient, Polypharmacy, Readmission
Interventions
Pharmacist-led Hospital Discharge Care Intervention
Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
55 Years and older
Enrollment
6,478 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced May 22, 2026, 2:52 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Polypharmacy, Pharmacogenomic Testing
Interventions
Multigene pharmacogenomics test
Genetic
Lead sponsor
Geisinger Clinic
Other
Eligibility
65 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced May 22, 2026, 2:52 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Primary Open Angle Glaucoma, Open Angle Glaucoma
Interventions
Minimally Invasive Micro Sclerostomy Device
Device
Lead sponsor
Sanoculis Ltd
Industry
Eligibility
40 Years to 85 Years
Enrollment
129 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced May 22, 2026, 2:52 AM EDT
Recruiting No phase listed Observational
View directory record Official record
Conditions
Adverse Drug Reaction (ADR), Polypharmacy Patients
Interventions
Not listed
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bryan, Texas
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced May 22, 2026, 2:52 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Polypharmacy
Interventions
TEAM Strategy
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 25, 2024 · Synced May 22, 2026, 2:52 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Geriatric Assessment, Frail Elderly, Skilled Nursing Facilities, Patient-centered Care
Interventions
Deprescribing intervention
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced May 22, 2026, 2:52 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Polypharmacy, Care Transitions, Geriatric Syndromes
Interventions
Shed-Meds: A Patient-Centered Deprescribing Intervention
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
50 Years and older
Enrollment
372 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 18, 2023 · Synced May 22, 2026, 2:52 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Polypharmacy, Decision-making
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced May 22, 2026, 2:52 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
COVID, Drug Effect, Drug Interaction, Adverse Drug Event
Interventions
Simulation of Repurposed Drugs for COVID-19
Other
Lead sponsor
Tabula Rasa HealthCare
Industry
Eligibility
55 Years and older
Enrollment
12,873 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced May 22, 2026, 2:52 AM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
COVID, Drug Effect, Drug Interaction, Adverse Drug Event
Interventions
Not listed
Lead sponsor
Tabula Rasa HealthCare
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Sep 1, 2022 · Synced May 22, 2026, 2:52 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Adverse Drug Event
Interventions
Audit and feedback - letter and report
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
Not listed
Enrollment
11,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 22, 2021 · Synced May 22, 2026, 2:52 AM EDT
Completed No phase listed Observational Results available
View directory record Official record
Conditions
Pharmacogenetic Testing
Interventions
Genecept Assay and G-DIG decision tool
Genetic
Lead sponsor
Seattle Institute for Biomedical and Clinical Research
Other
Eligibility
18 Years to 75 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Apr 22, 2024 · Synced May 22, 2026, 2:52 AM EDT
Completed No phase listed Observational Results available
View directory record Official record
Conditions
Neurologic Disorder, Chronic Disease, Pediatric Disorder
Interventions
Parent-Reported Symptom Assessment
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
1 Day to 17 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 20, 2023 · Synced May 22, 2026, 2:52 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Cytochrome P450 CYP2D6 Enzyme Deficiency, Poor Metabolizer Due to Cytochrome P450 CYP2D6 Variant, Ultrarapid Metabolizer Due to Cytochrome P450 CYP2D6 Variant, Extensive Metabolizer Due to Cytochrome P450 CYP2D6 Variant, Cytochrome P450 CYP2C9 Enzyme Deficiency, Cytochrome P450 CYP2C19 Enzyme Deficiency, Drug Metabolism, Poor, CYP2D6-RELATED, Drug Metabolism, Poor, CYP2C19-RELATED, CYP2D6 Polymorphism
Interventions
Pharmacogenetic testing, Software-based drug & gene interaction risk analysis, MTM
Genetic · Other
Lead sponsor
Genelex Corporation
Industry
Eligibility
65 Years and older
Enrollment
341 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced May 22, 2026, 2:52 AM EDT
Recruiting Phase 4 Interventional
View directory record Official record
Conditions
Drug Interactions, Primary Prevention, Cardiometabolic Syndrome, LDL-Cholersterol Lowering
Interventions
Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2025 · Synced May 22, 2026, 2:52 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Polypharmacy
Interventions
Clinical decision support (CDS)-Commitment nudge, Clinician education, Clinical decision support (CDS)-Justification nudge
Behavioral · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
786 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced May 22, 2026, 2:52 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Surgery
Interventions
Wellness Program
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced May 22, 2026, 2:52 AM EDT