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ClinicalTrials.gov public records Last synced Oct 28, 2026, 11:12 AM EDT

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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Post-stroke Aphasia Clear all
Recruiting Not applicable Interventional

Targeted TDCS to Enhance Speech-Language Treatment Outcome in Persons With Chronic Post-Stroke Aphasia.

NCT04432883
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Active Comparator: Experimental: Active cathodal tDCS + language training, Sham Comparator: Placebo cathodal tDCS + Speech and language
Device · Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
25 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 28, 2026, 11:12 AM EDT
Not listed Phase 1 Interventional

Levetiracetam (Keppra) to Improve Chronic Aphasia in Post-stroke Patients.

NCT00227461
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Wait first, then levetiracetam, Levetiracetam first, then wait
Drug
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2021
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 17, 2021 · Synced Oct 28, 2026, 11:12 AM EDT
Not listed Not applicable Interventional

Studying Language With Brain Stimulation in Aphasia

NCT05660304
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Cortico-cortical paired associative stimulation, Sham cortico-cortical paired associative stimulation
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Oct 28, 2026, 11:12 AM EDT
Recruiting Not applicable Interventional

Combined Exercise and Targeted Therapy for Post-Stroke Reading Deficits

NCT06213272
View directory record Official record
Conditions
Stroke, Aphasia, Reading Disorder
Interventions
Phono-Motor Therapy, Aerobic Exercise Training (AET), Stretching
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 28, 2026, 11:12 AM EDT
Recruiting Not applicable Interventional

Post-Stroke Aphasia TMS

NCT06974279
View directory record Official record
Conditions
Aphasia, Stroke, Language
Interventions
Precision TMS with SFA, Control TMS with SFA
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2036
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 28, 2026, 11:12 AM EDT
Completed Not applicable Interventional

fMRI of Language Recovery Following Stroke in Adults

NCT00843427
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
CIAT
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 11, 2018 · Synced Oct 28, 2026, 11:12 AM EDT
Completed Not applicable Interventional Results available

Adapting Acceptance and Commitment Therapy for Stroke Survivors With Aphasia

NCT04984239
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Acceptance and Commitment Therapy for aphasia
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 25, 2025 · Synced Oct 28, 2026, 11:12 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Phonological Treatment Paired With Intensive Speech Therapy Promotes Reading Recovery in Chronic Aphasia

NCT02799017
View directory record Official record
Conditions
Aphasia, Language
Interventions
Intensive Phonology Treatment, Intensive SFA Treatment
Other
Lead sponsor
Austin Speech Labs
Other
Eligibility
20 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 28, 2026, 11:12 AM EDT
Recruiting Not applicable Interventional

Effect of Community Choir Singing in People With Chronic Post-stroke Aphasia

NCT06368323
View directory record Official record
Conditions
Aphasia
Interventions
Choir singing, Usual care
Behavioral · Other
Lead sponsor
University of Ottawa
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Oct 28, 2026, 11:12 AM EDT
Not yet recruiting Not applicable Interventional

Combined Aphasia and Robot-Assisted Arm Treatment for Chronic Stroke Survivors

NCT07000019
View directory record Official record
Conditions
Stroke, Aphasia Following Cerebral Infarction, Hemiparesis After Stroke
Interventions
CARAT: combined aphasia and robot-assisted arm therapy, Robot-assisted arm therapy
Behavioral
Lead sponsor
New York Medical College
Other
Eligibility
18 Years to 90 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 28, 2026, 11:12 AM EDT
Completed Not applicable Interventional

Effects of Neuromodulation on Verbal Fluency in Post-stroke Aphasia

NCT02270866
View directory record Official record
Conditions
Post-stroke Aphasia
Interventions
TNM Device
Device
Lead sponsor
Scion NeuroStim
Industry
Eligibility
18 Years to 75 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 28, 2026, 11:12 AM EDT
Completed No phase listed Observational

Stroke-like Migraine Attacks After Radiation Treatment (SMART) Syndrome Language Intervention

NCT03662295
View directory record Official record
Conditions
Migraine Disorders, Aphasia
Interventions
Language treatment
Behavioral
Lead sponsor
Quality Living, Inc.
Other
Eligibility
19 Years to 65 Years
Enrollment
1 participant
Timeline
2018 – 2019
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 28, 2026, 11:12 AM EDT
Completed Not applicable Interventional Results available

Post-Stroke Aphasia and Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment Study

NCT01512264
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
Magstim SuperRapid
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Oct 28, 2026, 11:12 AM EDT
Completed Not applicable Interventional Results available

Word Retrieval in the Wild in People With Post-Stroke Aphasia

NCT05338216
View directory record Official record
Conditions
Aphasia, Acquired
Interventions
Traditional EMA, Micro-Interaction EMA
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
18 Years to 89 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 28, 2026, 11:12 AM EDT
Recruiting Phase 2 Interventional

Transcranial Magnetic Stimulation + Language Therapy to Treat Subacute Aphasia

NCT06968663
View directory record Official record
Conditions
Stroke, Aphasia, Aphasia Following Cerebral Infarction
Interventions
Transcranial Magnetic Stimulation (TMS), Modified Constraint Induced Language Therapy (mCILT)
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 85 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 28, 2026, 11:12 AM EDT
Withdrawn Not applicable Interventional

Effects of Transcranial Direct Current Stimulation in Post-stroke Aphasia

NCT02622945
View directory record Official record
Conditions
Aphasia
Interventions
Active tDCS plus Speech-Language Therapy, Sham plus Speech-Language Therapy
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 26, 2018 · Synced Oct 28, 2026, 11:12 AM EDT
Completed Not applicable Interventional

Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy

NCT06891638
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
Schedule of tDCS administration
Device
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
West Orange, New Jersey • Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 28, 2026, 11:12 AM EDT
Recruiting Not applicable Interventional

Recovery From Post-Stroke Aphasia With rTMS Targeting Left or Right Anterior Temporal Lobe

NCT07608588
View directory record Official record
Conditions
Stroke, Aphasia
Interventions
continuous Theta Burst Stimulation, intermittent Theta Burst Stimulation, Transcranial Magnetic Stimulation Sham, Semantic Feature Analysis
Device · Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated May 29, 2026 · Synced Oct 28, 2026, 11:12 AM EDT
Terminated Not applicable Interventional Results available

Transcranial Direct Current Stimulation for Post-Stroke Aphasia

NCT02461355
View directory record Official record
Conditions
Stroke
Interventions
Aphasia therapy, Anodal tDCS, Sham tDCS
Behavioral · Device
Lead sponsor
Columbia University
Other
Eligibility
21 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Maywood, New Jersey
Source: ClinicalTrials.gov public record
Updated May 9, 2019 · Synced Oct 28, 2026, 11:12 AM EDT
Completed Not applicable Interventional Results available

Using Transcranial Direct Current Stimulation (tDCS) to Improve Post-Stroke Aphasia

NCT01709383
View directory record Official record
Conditions
Aphasia
Interventions
Transcranial Direct Current Stimulation, Sham Stimulation
Device
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 6, 2017 · Synced Oct 28, 2026, 11:12 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Alternating Current Stimulation (tACS) in Aphasia

NCT04375722
View directory record Official record
Conditions
Aphasia, Stroke
Interventions
tACS
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Oct 28, 2026, 11:12 AM EDT
Terminated Not applicable Interventional

Speech and Language Therapy After Stroke

NCT00713050
View directory record Official record
Conditions
Ischemic Stroke
Interventions
Imitate Therapy
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
Not listed
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
2
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2013 · Synced Oct 28, 2026, 11:12 AM EDT
Not listed Not applicable Interventional

Using Augmentative & Alternative Communication to Promote Language Recovery for People With Post-Stroke Aphasia

NCT04081207
View directory record Official record
Conditions
Post-stroke Aphasia, Aphasia
Interventions
AAC for Language Recovery (AAC-LaRc)
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Oct 28, 2026, 11:12 AM EDT
Recruiting Phase 2 Interventional

Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia

NCT06842745
View directory record Official record
Conditions
Aphasia, Stroke, Aphasia Following Cerebral Infarction, Aphasia, Acquired
Interventions
Transcranial Magnetic Stimulation (TMS), Speech-Language Therapy (SLT)
Device · Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
40 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 28, 2026, 11:12 AM EDT