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Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Postoperative Quality of Recovery Clear all
Completed Not applicable Interventional

Enhanced Recovery After Surgery (ERAS) for Ambulatory TURBT

NCT05905276
View directory record Official record
Conditions
Bladder Cancer
Interventions
ERAS Protocol, Standard of Care
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional

Pain Control for Anterior Cruciate Ligament Reconstruction Patients With Adductor Canal or Femoral Perineural Infusions

NCT03208478
View directory record Official record
Conditions
Pain, Postoperative, Anterior Cruciate Ligament Injury
Interventions
Adductor Canal perineural catheter placement, Femoral Nerve perineural catheter placement, Nimbus pump (Infutronix)
Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2023 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional

Effect of Patient Preference for Intraoperative Opioid Use on Early Postoperative Quality of Recovery

NCT06855641
View directory record Official record
Conditions
Opioid Analgesia, Quality of Recovery (QoR-15), Outcome Assessment, Opioid Free Anesthesia
Interventions
Opioid based Anesthesia, opioid free anesthesia
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Phase 4 Interventional

Opioid Free Anesthesia and Bariatric Surgery

NCT04144153
View directory record Official record
Conditions
Postoperative Quality of Recovery
Interventions
Opioid Free Total Intravenous Anesthesia, Total Intravenous anesthesia with opioid
Combination Product
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 70 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional

Enhanced Recovery After Surgery Gynecology Oncology

NCT02864277
View directory record Official record
Conditions
Malignant Female Reproductive System Neoplasm
Interventions
No Intervention Conventional Strategy, ERAS
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhanced Recovery After Spine Surgery

NCT02949518
View directory record Official record
Conditions
Enhanced Recovery After Surgery, Spine Surgery
Interventions
Enhanced Recovery Pathway (ERP) for Spine
Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
21 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 27, 2020 · Synced Jul 22, 2026, 5:54 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Feasibility of Breathwork Intervention With Older Adults After Knee Surgery

NCT07464860
View directory record Official record
Conditions
Surgical Stress Response, Stress Physiological, Stress Physiology, Stress Psychological, Breathing Techniques, Breathing Exercises, Hypothalamic Pituitary Adrenal, Relaxation, Relaxation Therapy, Cortisol, Postoperative Pain, Postoperative Anxiety, Postoperative Depression, Quality of Recovery (QoR-15)
Interventions
A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
65 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional Results available

Perioperative Systemic Acetaminophen to Improve Postoperative Quality of Recovery After Ambulatory Breast Surgery

NCT01852955
View directory record Official record
Conditions
Pain
Interventions
IV acetaminophen, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 13, 2016 · Synced Jul 22, 2026, 5:54 AM EDT
Recruiting Early Phase 1 Interventional

Pain Control and Quality of Recovery After Intravenous Methadone Versus Intravenous Remifentanil in Craniotomy Surgery

NCT06810336
View directory record Official record
Conditions
Brain Injury, Brain Tumors, Craniotomy Surgery, Pain, Postoperative, Postoperative Care
Interventions
Remifentanil, Methadone
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jul 22, 2026, 5:54 AM EDT
Not yet recruiting Phase 3 Interventional

Methadone for Enhanced Postoperative Analgesia in Intermediate-Risk Noncardiac Surgery (MELODY)

NCT07565870
View directory record Official record
Conditions
Postoperative Pain, Recovery
Interventions
Intravenous Methadone, Short-acting Opioids Intraoperative analgesia
Drug
Lead sponsor
Alexandre P. Joosten
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jul 22, 2026, 5:54 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Quality of Recovery From Mastectomy With and Without PECS Blocks

NCT05795413
View directory record Official record
Conditions
Post Operative Pain, Quality of Recovery After Mastectomy
Interventions
Mastectomy with PECS blocks, Liposomal bupivacaine
Procedure · Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Jul 22, 2026, 5:54 AM EDT
Recruiting Phase 4 Interventional

Methadone and Quality of Postoperative Recovery

NCT03168958
View directory record Official record
Conditions
Quality of Recovery Scores
Interventions
Methadone, Saline
Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 90 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 23, 2020 · Synced Jul 22, 2026, 5:54 AM EDT
Not listed No phase listed Observational

Geriatric Oncology Surgical Assessment and Functional rEcovery After Surgery

NCT03299270
View directory record Official record
Conditions
Elderly, Solid Malignancy
Interventions
Questionnaires
Other
Lead sponsor
AUSL ROMAGNA
Other
Eligibility
70 Years and older
Enrollment
1,004 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
4
States / cities
Weston, Florida • Boston, Massachusetts • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated May 8, 2019 · Synced Jul 22, 2026, 5:54 AM EDT
Terminated Not applicable Interventional Results available

Single Shot vs Catheter Infraclavicular Brachial Plexus Block After Distal Radius Fracture Repair

NCT02744352
View directory record Official record
Conditions
Distal Radius Fracture, Post Operative Pain Control
Interventions
20ml bolus of 0.5% ropivicaine, 0.2% of ropivacaine at 8 milliliter/hour
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2020 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Phase 1 Interventional Results available

Pectointercostal Fascial Plane Block (PIFB) Alone Versus PIFB With Rectus Sheath Block (RSB) in Cardiac Surgery

NCT04908449
View directory record Official record
Conditions
Coronary Artery Disease, Postoperative Pain, Respiratory Failure
Interventions
Rectus sheath block with bupivacaine
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional

Microlearning-Based Health Education for Ambulatory Surgery Patients

NCT07221435
View directory record Official record
Conditions
Microlearning
Interventions
Microlearning education
Behavioral
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional Results available

The Effect of Intraoperative Esmolol to Improve Postoperative Quality of Recovery and Pain After Ambulatory Surgery

NCT01782898
View directory record Official record
Conditions
Pain
Interventions
Esmolol administered at a rate of 0.5 mg/kg followed by an infusion of 5-15 mcg/kg/min, Placebo Comparator: .9 normal saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 10, 2016 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional Results available

A Dose Ranging Effect of Preoperative Diphenhydramine on Postoperative Quality of Recovery After Ambulatory Surgery

NCT01451762
View directory record Official record
Conditions
Surgery, Pain
Interventions
.9 normal saline, 25 mg diphenhydramine IV, 50 mg diphenhydramine IV
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 13, 2014 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Phase 3 Interventional

THRIVE Feasibility Trial

NCT05346588
View directory record Official record
Conditions
Surgery--Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia Emergence Delirium, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Nausea, Postoperative, Anesthesia Morbidity, Depression, Sleep Disorders, Circadian Rhythm
Interventions
Anesthetic technique Propofol TIVA, Anesthetic technique inhaled agent
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Stanford, California • Ann Arbor, Michigan • St Louis, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 23, 2023 · Synced Jul 22, 2026, 5:54 AM EDT
Not listed Not applicable Interventional

TAP Catheters Versus Intrathecal Morphine for Cesarean Section

NCT01593280
View directory record Official record
Conditions
Abdominal Muscles/Ultrasonography, Adult, Anesthetics, Local/Administration & Dosage, Ropivacaine/Administration & Dosage, Ropivacaine/Analogs & Derivatives, Cesarean Section, Humans, Nerve Block/Methods, Pain Measurement/Methods, Pain, Postoperative/Prevention & Control, Ultrasonography, Interventional
Interventions
TAP catheter, intrathecal morphine
Device · Drug
Lead sponsor
Stamford Anesthesiology Services, PC
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 7, 2012 · Synced Jul 22, 2026, 5:54 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Can Post-operative TAP Block Improve Quality of Recovery After C-sections in Patients on Methadone Maintenance?

NCT01644864
View directory record Official record
Conditions
Uncontrolled Postoperative Pain
Interventions
0.375% ROPIVACAINE, placebo
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 40 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2017 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Phase 2 Interventional Results available

The Impact of Preoperative Olanzapine on Quality of Recovery After Discharge From Ambulatory Surgery

NCT05676294
View directory record Official record
Conditions
Postoperative Nausea and Vomiting
Interventions
Olanzapine, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
398 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Jul 22, 2026, 5:54 AM EDT
Completed Not applicable Interventional Results available

Transversus Abdominis Plane (TAP) Block Laparoscopic Hysterectomy

NCT01074229
View directory record Official record
Conditions
Postoperative Pain
Interventions
Placebo, Drug .5% Ropivacaine, 20 cc of 0.25% ropivacaine
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 7, 2014 · Synced Jul 22, 2026, 5:54 AM EDT
Recruiting Not applicable Interventional

rTMS for Postoperative Brain Tumor Patients

NCT07530536
View directory record Official record
Conditions
Brain Tumors, Transcranial Magnetic Stimulation, Motor Deficit, Quality of Life
Interventions
Transcranial magnetic stimulation (TMS)
Device
Lead sponsor
Brian J.Gill
Other
Eligibility
22 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jul 22, 2026, 5:54 AM EDT