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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Presbycusis Clear all
Completed No phase listed Observational Accepts healthy volunteers

Sight and Hearing Investigation Into Effects on Delirium

NCT06176625
View directory record Official record
Conditions
Hearing Loss, Hearing Loss, Age-Related, Hearing Disability, Delirium, Delirium in Old Age, Delirium of Mixed Origin, Delirium With Dementia, Delirium on Emergence, Delirium, Cause Unknown, Delirium Superimposed on Dementia, Delirium Confusional State, Delirium;Non Alcoholic, Hearing Loss, Bilateral, Hearing Loss, Sensorineural, Hearing Loss, Functional, Hearing Loss, High-Frequency, Hearing
Interventions
Communication Signage, Amplifier Use
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
1,543 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Sep 6, 2026, 1:05 PM EDT
Completed Not applicable Interventional

Hearing Aid Education and Adaptation System

NCT02839759
View directory record Official record
Conditions
Hearing Loss
Interventions
TELLYHealth
Other
Lead sponsor
Healthcare Technologies and Methods, LLC
Industry
Eligibility
50 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
Gainesville, Florida • Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated May 13, 2020 · Synced Sep 6, 2026, 1:05 PM EDT
Recruiting Not applicable Interventional

Benefits of Choir for Older Adults With Unaddressed Hearing Loss (WP2)

NCT06580847
View directory record Official record
Conditions
Hearing Loss, Age-Related, Speech Intelligibility, Psychosocial Functioning
Interventions
Group Singing, Audiobook Club
Behavioral
Lead sponsor
Toronto Metropolitan University
Other
Eligibility
60 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 6, 2026, 1:05 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Early Age-Related Hearing Loss Investigation Pilot Study

NCT05970211
View directory record Official record
Conditions
Hearing Loss
Interventions
Phonak Audeo Lumity Receiver in Canal Hearing Aid
Device
Lead sponsor
University of South Florida
Other
Eligibility
55 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced Sep 6, 2026, 1:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hearing for Communication and Resident Engagement

NCT04575051
View directory record Official record
Conditions
Hearing Loss, Age-Related
Interventions
Consult Model, Engage Model
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
684 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Sep 6, 2026, 1:05 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Hearing Loss and Communication Needs in a Group Care Setting for Older Adults

NCT04659967
View directory record Official record
Conditions
Age-related Hearing Loss
Interventions
Virtual Training
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
3
States / cities
Boston, Massachusetts • West Springfield, Massachusetts • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 5, 2022 · Synced Sep 6, 2026, 1:05 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Hearing Healthcare Assessment in Rural Communities

NCT05786794
View directory record Official record
Conditions
Hearing Loss, Adult-Onset, Hearing Loss, Age-Related
Interventions
Patient Navigation Program for Hearing Health Care
Behavioral
Lead sponsor
Matthew Bush, MD
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
9
States / cities
Campbellsville, Kentucky • Campton, Kentucky • Elkton, Kentucky + 4 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Sep 6, 2026, 1:05 PM EDT
Recruiting No phase listed Observational

Cross-sectional and Prospective Study to Characterize Early-onset Presbycusis

NCT06354010
View directory record Official record
Conditions
Sensorineural Hearing Loss, Bilateral
Interventions
Genotyping, Audiological assessments
Genetic · Other
Lead sponsor
Sensorion
Industry
Eligibility
30 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 6, 2026, 1:05 PM EDT
Completed Not applicable Interventional Results available

Impact of Hearing Aid Service-delivery Model and Technology on Patient Outcomes

NCT03579563
View directory record Official record
Conditions
Presbycusis
Interventions
AUD fitting, OTC fitting, High-end HA, Low-end HA
Other · Device
Lead sponsor
Yu-Hsiang Wu
Other
Eligibility
55 Years to 85 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Iowa City, Iowa • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Sep 6, 2026, 1:05 PM EDT
Completed Not applicable Interventional Results available

At-home Auditory Training Clinical Trial

NCT01950013
View directory record Official record
Conditions
Presbycusis, Aging, Hearing Loss
Interventions
Auditory training program, Sham Comparator: Active Control
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
55 Years to 79 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Sep 6, 2026, 1:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural Changes in the Aging Auditory System

NCT00264407
View directory record Official record
Conditions
Progesterone, Estrogens, Hearing, Psychoacoustics, Auditory Perceptual Disorders
Interventions
Hormone Replacement Therapy - HRT
Drug
Lead sponsor
University of Rochester
Other
Eligibility
60 Years to 86 Years · Female only
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
2
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2005 · Synced Sep 6, 2026, 1:05 PM EDT
Completed Not applicable Interventional Results available

Variability In Hearing Aid Outcomes In Older Adults

NCT02448706
View directory record Official record
Conditions
Hearing Loss, Presbycusis
Interventions
Hearing Aid Fitting A, Hearing Aid Fitting B
Device
Lead sponsor
Northwestern University
Other
Eligibility
54 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 16, 2020 · Synced Sep 6, 2026, 1:05 PM EDT
Completed Phase 4 Interventional Results available

Treating Hearing Loss to Improve Mood and Cognition in Older Adults

NCT03321006
View directory record Official record
Conditions
Hearing Loss, Depression
Interventions
Phonak Audeo B-R 90 hearing aid device (Active), Duloxetine or escitalopram, Audeo B-R 90 hearing aid device (Sham)
Device · Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
60 Years to 99 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 3, 2021 · Synced Sep 6, 2026, 1:05 PM EDT
Completed Phase 2 Interventional Results available

Efficacy and Safety of AUT00063 Versus Placebo in Age-Related Hearing Loss

NCT02345031
View directory record Official record
Conditions
Age-Related Hearing Loss
Interventions
AUT00063, Placebo
Drug
Lead sponsor
Autifony Therapeutics Limited
Industry
Eligibility
50 Years to 89 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
13
States / cities
Sacramento, California • Colorado Springs, Colorado • Boca Raton, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2018 · Synced Sep 6, 2026, 1:05 PM EDT
Recruiting Not applicable Interventional

Barriers and Facilitators to OTC Hearing Aids Success

NCT06499805
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Presbycusis
Interventions
Audiologist-based fitting, Over-the-counter fitting
Device
Lead sponsor
Yu-Hsiang Wu
Other
Eligibility
18 Years to 89 Years
Enrollment
360 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
2
States / cities
Iowa City, Iowa • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 20, 2025 · Synced Sep 6, 2026, 1:05 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Unilateral vs Bilateral Hearing Aids for the Treatment of Age-related Hearing Loss

NCT04739436
View directory record Official record
Conditions
Hearing Loss
Interventions
Hearing amplification
Device
Lead sponsor
Duke University
Other
Eligibility
50 Years and older
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Durham, North Carolina • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 9, 2025 · Synced Sep 6, 2026, 1:05 PM EDT
Recruiting Phase 1Phase 2 Interventional

A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound

NCT07304024
View directory record Official record
Conditions
Central Auditory Processing Disorder, Hearing Impaired (Partially), Hearing, Hearing Abnormality, Hearing Disability, Hearing Disorder, Hearing Disorders, Hearing Impairment, Sensorineural, Hearing Handicap, Hearing Impaired, Hearing Impairment, Hearing Loss, Central Auditory Disease, Noise Exposure, Noise Induced Hearing Loss, Noise-Induced Hearing Loss, Sound Perception, Myelin Degeneration, Myelinopathy, Myelin Integrity, Remyelination, Hidden Hearing Loss, Cocktail Party Skill, Cocktail Party Syndrome, CAPD, Age Problem
Interventions
Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise, Placebo Drug With Engineered Sound, Placebo - Placebo
Combination Product · Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
45 Years to 65 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 6, 2026, 1:05 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Speech in Noise Perception for Individuals With Age-related Hearing Loss

NCT07192757
View directory record Official record
Conditions
Presbycusis
Interventions
transcutaneous auricular vagus nerve stimulation, Sham Control
Device
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Sep 6, 2026, 1:05 PM EDT
Recruiting Not applicable Interventional

Early Age-Related Hearing Loss Investigation (EARHLI)

NCT06174038
View directory record Official record
Conditions
Alzheimer Disease, Hearing Loss, Cognitive Impairment
Interventions
Hearing Intervention, Health Education Intervention
Device · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
55 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 6, 2026, 1:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Predicting Success With Hearing Aids

NCT00371449
View directory record Official record
Conditions
Hearing Loss, Presbycusis
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Mountain Home, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Sep 6, 2026, 1:05 PM EDT
Completed Not applicable Interventional

Computer-Based Auditory Rehabilitation

NCT02147847
View directory record Official record
Conditions
Presbycusis
Interventions
Video game based training 1, Video game based training 2
Behavioral
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
50 Years to 85 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
3
States / cities
Boston, Massachusetts • Brighton, Massachusetts • New City, New York
Source: ClinicalTrials.gov public record
Updated Oct 17, 2016 · Synced Sep 6, 2026, 1:05 PM EDT
Completed Not applicable Interventional Results available

Evaluating Hearing Aid Service Delivery Models

NCT01788423
View directory record Official record
Conditions
Presbycusis, Aging, Hearing Loss
Interventions
hearing aid
Device
Lead sponsor
Indiana University
Other
Eligibility
55 Years to 79 Years
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Sep 6, 2026, 1:05 PM EDT
Completed Phase 1 Interventional

A Study Of The Effects Of PF-04958242 In Subjects With Age-Related Hearing Loss

NCT01518920
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
PF-04958242, Placebo
Drug
Lead sponsor
Biogen
Industry
Eligibility
50 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
11
States / cities
Anaheim, California • New Haven, Connecticut • South Miami, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2019 · Synced Sep 6, 2026, 1:05 PM EDT
Completed Not applicable Interventional Results available

Hearing Aid and Individuals With Cognitive Disorders

NCT04049643
View directory record Official record
Conditions
Presbycusis, Bilateral, Alzheimer Disease 2 Due to Apoe4 Isoform, Mild Cognitive Impairment
Interventions
Audiologist-based fitting, Service-only Fitting, Device-only fitting
Device
Lead sponsor
Yu-Hsiang Wu
Other
Eligibility
55 Years to 85 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Iowa City, Iowa • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Sep 6, 2026, 1:05 PM EDT