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ClinicalTrials.gov public records Last synced Oct 22, 2026, 3:07 AM EDT

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Showing 25–40 of 40 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Preterm Premature Ruptured Membranes Clear all

Conditions: Fetal Membranes, Premature Rupture
Interventions: Retention of Cerclage, Removal of Cerclage, Removal vs. Retention of Cervical Cerclage; Procedure
Lead sponsor: Obstetrix Medical Group; Industry
Eligibility: 18 Years to 60 Years · Female only
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2014
U.S. locations: 23
States / cities: Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 18 more

Conditions: Pregnancy, Prelabor Rupture of Membranes
Interventions: Membrane Sweep, No Membrane Sweep; Procedure
Lead sponsor: Tripler Army Medical Center; Federal
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Tripler AMC, Hawaii

Conditions: Preterm Premature Rupture of Membrane
Interventions: Vaginal cleansing with chlorhexidine gluconate solution; Other
Lead sponsor: Albany Medical College; Other
Eligibility: 18 Years to 50 Years · Female only
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2024
U.S. locations: 1
States / cities: Albany, New York

Conditions: Preterm Premature Rupture of the Membranes, Physical Activity
Interventions: Moderate Activity; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older · Female only
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: San Diego, California

Conditions: Antenatal Corticosteroids
Interventions: Antenatal corticosteroids; Other
Lead sponsor: St. Louis University; Other
Eligibility: 13 Years to 55 Years · Female only
Enrollment: 182 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Post Term Pregnancy, Premature Rupture of Membrane, Fetal Growth Retardation, Oligohydramnios, Gestational Diabetes, High Blood Pressure in Pregnancy
Interventions: Dilapan-S; Device
Lead sponsor: Medicem Technology s.r.o.; Other
Eligibility: 18 Years and older · Female only
Enrollment: 1,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2025
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Premature Rupture of Membranes
Interventions: Foley Catheter, Oxytocin; Device · Drug
Lead sponsor: Geisinger Clinic; Other
Eligibility: Female only
Enrollment: 201 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2016
U.S. locations: 5
States / cities: Phoenix, Arizona • Newark, Delaware • Allentown, Pennsylvania + 2 more

Conditions: Fetal Membranes, Premature Rupture, Preterm Premature Rupture of the Membranes, Oligohydramnios, Premature Birth
Interventions: There is no intervention associated with this study.; Other
Lead sponsor: American Alliance for pProm Support; Other
Eligibility: 14 Years to 55 Years · Female only
Enrollment: 3,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2030
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Preterm Prelabor Rupture of Membranes, PPROM
Interventions: Azithromycin (Azithro), Standard Azithromycin Dosing; Drug
Lead sponsor: Alexa Henderson; Other
Eligibility: Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Preterm Premature Rupture of Membranes (PPROM)
Interventions: Azithromycin, Erythromycin, Ampicillin, Amoxicillin; Drug
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 18 Years and older · Female only
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 3
States / cities: Austin, Texas • Galveston, Texas • Salt Lake City, Utah

Conditions: Pregnancy, Pre-term Premature Rupture of Membranes
Interventions: Bed Rest, Activity; Other
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 2
States / cities: Elmhurst, New York • New York, New York

Conditions: Preterm Birth, Premature Rupture of Membranes
Interventions: Not listed
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: Not listed
Enrollment: 6,838 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1999 – 2016
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Pregnancy, Preterm Labor, Maternal Fetal Factors, Preterm Birth
Interventions: Not listed
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 18 Years to 45 Years
Enrollment: 746 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Preterm Birth, Pregnancy
Interventions: Not listed
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: Up to 45 Years
Enrollment: 4,673 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1997 – 2014
U.S. locations: 2
States / cities: Bethesda, Maryland • Detroit, Michigan

Conditions: Premature Rupture of Fetal Membranes
Interventions: CRB, Pitocin; Device · Drug
Lead sponsor: Cook Group Incorporated; Industry
Eligibility: 18 Years and older · Female only
Enrollment: 129 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 4
States / cities: Tucson, Arizona • Tampa, Florida • Louisville, Kentucky + 1 more

Conditions: PPROM
Interventions: Speculum Exams, Digital Exams; Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: Female only
Enrollment: 86 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: St Louis, Missouri

Search by objective public record fields.

Removal Versus Retention of Cerclage in Preterm Premature Rupture of Membranes (PPROM)

Safety Study of Membrane Sweeping in Pregnancy

Vaginal Cleansing With Chlorhexidine Gluconate in Women With Preterm Pre-labor Rupture of Membranes

A Comparison of Bed Rest Versus Moderate Activity in Preterm Premature Rupture of Membranes (PPROM)

Repeat Antenatal Corticosteroids

Dilapan-S®: A Multicenter US E-registry

FOLCROM Trial: Foley Catheter in Rupture of Membranes

PPROM Registry (Preterm Premature Rupture of Membranes)

Extended Azithromycin Treatment in Prelabor Rupture of Membranes

Treatment of ppROM With Erythromycin vs. Azithromycin Trial

Preterm Premature Rupture of Membranes (PPROM): Bed Rest Versus Activity Trial

Microarray Expression Profiling to Identify Stereotypic mRNA Profiles in Human Parturition

Biomarkers in Obstetrical Complications

Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients With Preterm Labor and Premature Rupture of Membranes

Evaluation of CRB in PROM Patients

Digital vs. Speculum Exams for PPROM