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Showing 1–24 of 43 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Procedural Anxiety Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating the Feasibility of VR for Pediatric Renal Biopsies

NCT05267704
View directory record Official record
Conditions
Pain, Procedural, Procedural Anxiety, Sedation Complication
Interventions
Oculus Go Virtual Reality Headset
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
5 Years to 17 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Jul 22, 2026, 2:03 AM EDT
Recruiting Not applicable Interventional

Oral Surgery Virtual Reality Glasses Study

NCT06723158
View directory record Official record
Conditions
Procedural Anxiety, Procedural Pain
Interventions
Virtual reality (VR) glasses with relaxation module
Other
Lead sponsor
Boston University
Other
Eligibility
16 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 22, 2026, 2:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

REducing Anxiety in CHildren Undergoing Procedures

NCT03054077
View directory record Official record
Conditions
Ambulatory Surgery
Interventions
iPad with downloaded games
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
4 Years to 12 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 9, 2017 · Synced Jul 22, 2026, 2:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Can Virtual Reality Reduce Pain and Anxiety During Blood Draw

NCT04449341
View directory record Official record
Conditions
Procedural Anxiety, Procedural Pain
Interventions
Oculus Go headset with Ocean Rift application
Device
Lead sponsor
C.R.Darnall Army Medical Center
Federal
Eligibility
18 Years to 50 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Jul 12, 2021 · Synced Jul 22, 2026, 2:03 AM EDT
Not yet recruiting Not applicable Interventional

Effect of Music on Pain and Anxiety During Nail Biopsies

NCT07518953
View directory record Official record
Conditions
Procedural Anxiety, Pain
Interventions
Music intervention, Local anesthesia injections
Behavioral · Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jul 22, 2026, 2:03 AM EDT
Completed Phase 2 Interventional Results available

Evaluation of DEX-IN During Outpatient Procedures

NCT03348423
View directory record Official record
Conditions
Pain
Interventions
DEX-IN, Fentanyl, Placebo
Drug
Lead sponsor
Baudax Bio
Industry
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Jul 22, 2026, 2:03 AM EDT
Not yet recruiting Not applicable Interventional

Technology-Based Distractions for Minor Procedures

NCT06924814
View directory record Official record
Conditions
Anxiety, Procedural Anxiety
Interventions
Standard of Care, Immersive technology
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
4 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jul 22, 2026, 2:03 AM EDT
Active, not recruiting Not applicable Interventional

VR-PAT for Pain and Anxiety Management During Pediatric Dermatologic Laser Procedures

NCT05645224
View directory record Official record
Conditions
Procedural Anxiety, Procedural Pain
Interventions
VR-PAT
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
5 Years to 25 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 22, 2026, 2:03 AM EDT
Completed Not applicable Interventional Results available

Impact of Virtual Reality on Pre-procedural anxieTy Prior to Heart cathEterIzAtion - VR-THEIA

NCT03662607
View directory record Official record
Conditions
Preprocedure Anxiety
Interventions
Virtual reality experience
Behavioral
Lead sponsor
Corewell Health West
Other
Eligibility
18 Years to 75 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Jul 22, 2026, 2:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pain, Anxiety During Interventional Spine Procedures

NCT04257019
View directory record Official record
Conditions
Pain, Low Back Pain, Procedural Pain, Procedural Anxiety
Interventions
Lavender oil, Almond oil, Water
Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 22, 2020 · Synced Jul 22, 2026, 2:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Technology-Based Distractions During Minor Procedures

NCT03628989
View directory record Official record
Conditions
Pain, Anxiety, Procedural Anxiety
Interventions
Use of Virtual Technology
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
Up to 17 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Jul 22, 2026, 2:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nitrous Oxide Use in Minor Procedures

NCT01911351
View directory record Official record
Conditions
Laceration, Abscess
Interventions
Nitrous Oxide
Drug
Lead sponsor
New York City Health and Hospitals Corporation
Other
Eligibility
3 Years to 12 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Apr 10, 2016 · Synced Jul 22, 2026, 2:03 AM EDT
Not yet recruiting Phase 4 Interventional

Remimazolam Versus Dexmedetomidine for Sedation During Neuraxial

NCT07651956
View directory record Official record
Conditions
Pregnant People, Anxiety
Interventions
Remimazolam, Dexmedetomidine
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Jul 22, 2026, 2:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Online Mindfulness-Based Intervention to Decrease Pre-Procedural Anxiety Before a First-Time Screening Colonoscopy

NCT06233253
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
Best Practice, Medical Chart Review, Online Mindfulness Meditation, Survey Administration
Other · Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
45 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 23, 2025 · Synced Jul 22, 2026, 2:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Reality Goggle Utilization for Venipuncture Distraction

NCT04479735
View directory record Official record
Conditions
Pain, Procedural
Interventions
Virtual Reality Goggles
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
5 Years to 21 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jul 22, 2026, 2:03 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Self-Adjusted Nitrous Oxide: A Feasibility Study in the Setting of Vasectomy

NCT05895383
View directory record Official record
Conditions
Procedural Pain, Pain Catastrophizing, Procedural Anxiety
Interventions
Nitrous oxide
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
21 Years to 85 Years · Male only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Jul 22, 2026, 2:03 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Lavender Aromatherapy to Decrease Anxiety/Pain Perception During Office Hysteroscopy

NCT06316934
View directory record Official record
Conditions
Anxiety, Pain, Procedural
Interventions
Lavandula angustifolia, Aura Cacia, Placebo
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Jul 22, 2026, 2:03 AM EDT
Not listed Not applicable Interventional

Virtual Reality for Alleviation of Peripheral IV Placement-Associated Discomfort

NCT03740607
View directory record Official record
Conditions
Procedural Anxiety, Procedural Pain, Perioperative Care
Interventions
Virtual reality, Peripheral intravenous catheter placement
Device · Procedure
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Jul 22, 2026, 2:03 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Breathwork Training Reduces Anxiety In Outpatient Gastrointestinal Procedures

NCT07647341
View directory record Official record
Conditions
Anxiety
Interventions
paced breathwork
Behavioral
Lead sponsor
Calm and Sense Technologies LLC
Industry
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Jupiter, Florida
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 22, 2026, 2:03 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Remimazolam Sedation for Nerve Blocks

NCT05415202
View directory record Official record
Conditions
Procedural Anxiety, Procedural Pain
Interventions
Remimazolam 20 MG [Byfavo]
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Jul 22, 2026, 2:03 AM EDT
Recruiting Not applicable Interventional

Virtual Reality for Pain Control in US-Guided Obstetric Needle Procedures

NCT07094451
View directory record Official record
Conditions
Procedural Pain
Interventions
Virtual Reality, Ultrasound
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Jul 22, 2026, 2:03 AM EDT
Completed Not applicable Interventional

Use of an Adaptive Sensory Environment in Autism Spectrum Disorder (ASD) Patients in the Perioperative Environment

NCT04994613
View directory record Official record
Conditions
Autism Spectrum Disorder, Anesthesia, Procedural Anxiety, Sensory Processing Disorder
Interventions
Sensory adaptive environment
Other
Lead sponsor
Dayton Children's Hospital
Other
Eligibility
3 Years to 12 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced Jul 22, 2026, 2:03 AM EDT
Terminated Phase 4 Interventional

Intranasal Ketamine for Anxiolysis in Pediatric Emergency Department Patients

NCT03043430
View directory record Official record
Conditions
Anxiety, Pediatric ALL, Procedural Anxiety
Interventions
Ketamine 100 MG/ML, Midazolam 5 MG/ML
Drug
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
2 Years to 12 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Jul 22, 2026, 2:03 AM EDT
Completed Not applicable Interventional

Lavender Aromatherapy Spine Procedure Study

NCT04156009
View directory record Official record
Conditions
Spine Injuries and Disorders, Pain, Back
Interventions
Activated Lavender Elequil aromatabs® (#372), Unactivated Lavender Elequil aromatabs® (#372)
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 85 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Jul 22, 2026, 2:03 AM EDT