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ClinicalTrials.gov public records Last synced May 22, 2026, 12:13 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 101 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Prolapse, Vaginal Clear all
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Vaginal Delivery, Pelvic Organ Prolapse
Interventions
Materna Prep Device, Standard of Care (SOC)
Device · Other
Lead sponsor
Materna Medical
Industry
Eligibility
18 Years and older · Female only
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
22
States / cities
Birmingham, Alabama • Greenbrae, California • Los Angeles, California + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced May 22, 2026, 12:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Anterior Vaginal Wall Prolapse, Cystocele, Pelvic Organ Prolapse
Interventions
Polypropylene mesh (Polyform by Boston Scientific), Porcine Dermis (Pelvicol by CRBard), Anterior Colporrhaphy
Device · Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2018
U.S. locations
2
States / cities
Downey, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced May 22, 2026, 12:13 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
Laparoscopic Sacrocolopopexy, Posterior repair
Procedure
Lead sponsor
University of Oklahoma
Other
Eligibility
21 Years to 80 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced May 22, 2026, 12:13 AM EDT
Withdrawn Phase 2 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Atrophy of Vagina, Vaginal Ulceration, Vaginitis
Interventions
Estradiol, placebo
Drug · Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2015 · Synced May 22, 2026, 12:13 AM EDT
Completed Phase 4 Interventional Results available
View directory record Official record
Conditions
Urethra Issue, Pelvic Organ Prolapse, Urinary Incontinence, Vaginal Vault Prolapse, Cystocele, Uterine Prolapse, Vaginal Prolapse, Pelvic Floor Disorders
Interventions
Water-Based Vaginal Lubricant, lidocaine topical
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 31, 2023 · Synced May 22, 2026, 12:13 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Uterine Prolapse Without Vaginal Wall Prolapse
Interventions
NeuGuide™ System
Device
Lead sponsor
Pop Medical Solutions
Industry
Eligibility
36 Years to 84 Years · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
11
States / cities
Washington D.C., District of Columbia • Fort Lauderdale, Florida • Weston, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced May 22, 2026, 12:13 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Pelvic Organ Prolapse, Prolapse
Interventions
Reia Vaginal Pessary
Device
Lead sponsor
Reia, LLC
Industry
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced May 22, 2026, 12:13 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Prolapse, Vaginal, Stress Urinary Incontinence, Pessaries, Pain
Interventions
Perineal massage
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced May 22, 2026, 12:13 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Cystocele, Uterine Prolapse, Urinary Incontinence
Interventions
grafted anterior prolapse repair, sutured anterior vaginal prolapse repair
Device · Procedure
Lead sponsor
Kaiser Permanente
Other
Eligibility
21 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Downey, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced May 22, 2026, 12:13 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Extended timing of pessary care
Other
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced May 22, 2026, 12:13 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Vaginal Delivery, Pelvic Organ Prolapse
Interventions
Materna Prep Device
Device
Lead sponsor
Materna Medical
Industry
Eligibility
18 Years and older · Female only
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
15
States / cities
Birmingham, Alabama • Los Angeles, California • Mountain View, California + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2024 · Synced May 22, 2026, 12:13 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 25, 2010 · Synced May 22, 2026, 12:13 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Pelvic Organ Prolapse (POP)
Interventions
SSLF, ULS, PMT
Procedure · Behavioral
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
18 Years and older · Female only
Enrollment
374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
9
States / cities
Birmingham, Alabama • Bellflower, California • La Jolla, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 21, 2020 · Synced May 22, 2026, 12:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Not listed
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced May 22, 2026, 12:13 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Polytetrafluoroethylene, Polydioxanone
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
204 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
5
States / cities
Augusta, Georgia • Chicago, Illinois • Chapel Hill, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 18, 2019 · Synced May 22, 2026, 12:13 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Vaginal Vault Prolapse
Interventions
Vertessa® Lite Y mesh, Restorelle® Y mesh, Laparoscopic sacrocolpopexy, Robotic assisted laparoscopic sacrocolpopexy
Device · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced May 22, 2026, 12:13 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Vaginal Vault Prolapse, Sexual Function
Interventions
McCall culdoplasty
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced May 22, 2026, 12:13 AM EDT
Completed No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Urinary Incontinence, Pelvic Organ Prolapse, Surgery
Interventions
Vaginal Surgery
Procedure
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older · Female only
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 22, 2011 · Synced May 22, 2026, 12:13 AM EDT
Not listed Phase 4 Interventional
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
Liposomal Bupivacaine
Drug
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated May 9, 2021 · Synced May 22, 2026, 12:13 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Pelvic Organ Prolapse, Gynecologic Cancers, Uterine Leiomyomata, Adenomyosis, Endometrial Hyperplasia, Other Abnormal Uterine and Vaginal Bleeding, Pelvic Mass, Pelvic Pain
Interventions
Not listed
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced May 22, 2026, 12:13 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Vaginal Prolapse
Interventions
Not listed
Lead sponsor
Larry Sirls
Other
Eligibility
Female only
Enrollment
417 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 15, 2017 · Synced May 22, 2026, 12:13 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Uterovaginal Prolapse
Interventions
Uterosacral ligament suspension, Uphold® LITE
Procedure
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
183 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2025
U.S. locations
8
States / cities
Birmingham, Alabama • La Jolla, California • Albuquerque, New Mexico + 5 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced May 22, 2026, 12:13 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Hysterectomy, Sacrocolpopexy
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
5
States / cities
Augusta, Georgia • Chicago, Illinois • Chapel Hill, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2024 · Synced May 22, 2026, 12:13 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Pelvic Organ Prolapse
Interventions
Restorelle Direct Fix A, Restorelle Direct Fix P, Native Tissue Repair Anterior, Native Tissue Repair Posterior
Device · Procedure
Lead sponsor
Coloplast A/S
Industry
Eligibility
18 Years and older · Female only
Enrollment
810 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
33
States / cities
Agoura Hills, California • Stanford, California • Denver, Colorado + 30 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2022 · Synced May 22, 2026, 12:13 AM EDT