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Conditions: Pacemaker, Diastolic Dysfunction, Diastolic Heart Failure
Interventions: Adjustment of lower rate limit, Maintenance of lower rate limit; Device
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years and older
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Pancreatitis
Interventions: Naso jejunal feeding tube insertion, NG feeding tube insertion; Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 4
States / cities: Birmingham, Alabama • Gainesville, Florida • Indianapolis, Indiana + 1 more

Conditions: Primary Progressive Aphasia
Interventions: Intermittent theta burst stimulation; Device
Lead sponsor: HealthPartners Institute; Other
Eligibility: 40 Years to 90 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Healthy, Hypoxia
Interventions: STRYKER SUSTAINABILITY SOLUTIONS PULSE OXIMETERS; Device
Lead sponsor: Stryker Sustainability Solutions; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Coronary Artery Disease
Interventions: Ga-68 Galmydar, 13N-ammonia; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 99 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Malnutitrion, Cancer
Interventions: Indirect Calorimeter, Weight-Based Parenteral Nutrition Dosing; Device · Dietary Supplement
Lead sponsor: Fox Chase Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Insomnia
Interventions: Partner-Assisted Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: San Diego, California

Conditions: Post-Traumatic Stress Disorders
Interventions: Floatation-based reduced environmental stimulation therapy; Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 18 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: Adult
Interventions: Motor Sequence Task; Behavioral
Lead sponsor: University of South Carolina; Other
Eligibility: 18 Years to 40 Years
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Prolonged Labor, Failed Induction, Labor Dystocia
Interventions: Oxytocin rest; Other
Lead sponsor: Christiana Care Health Services; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Major Abdominal/GI Surgery
Interventions: HMB, Protein and HMB, ERAS; Dietary Supplement
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Fresno, California

Conditions: Postmenopausal Metabolic Health
Interventions: Resistance and aerobic exercise; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 40 Years to 120 Years · Female only
Enrollment: 49 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 3
States / cities: La Jolla, California • San Diego, California

Conditions: Arthrogryposis, Craniofacial Abnormalities
Interventions: Lactate, Glucose, and Adenosine Triphosphate Blood Levels, Physiological Stress Test, Functional Enquiry Form, Strength, Joint ROM, Girth and Length Measurements, Study Physical Examination, Observational Gait Analysis, Mental Health Interview; Other · Procedure
Lead sponsor: Freeman-Sheldon Research Group, Inc.; Other
Eligibility: Not listed
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2022
U.S. locations: 1
States / cities: Buckhannon, West Virginia

Conditions: Irritable Bowel Syndrome, Ulcerative Colitis, Inflammatory Bowel Disease
Interventions: Not listed
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 60 Years
Enrollment: 198 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Hypertension
Interventions: Position of arm while taking blood pressure measurement; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 134 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Coronary Artery Disease
Interventions: [O-15]-Water PET Myocardial Perfusion Imaging (MPI); Drug
Lead sponsor: MedTrace Pharma A/S; Industry
Eligibility: 18 Years and older
Enrollment: 215 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 6
States / cities: Iowa City, Iowa • Rochester, Minnesota • St Louis, Missouri + 3 more

Conditions: Heart Transplantation
Interventions: Bradykinin; Drug
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Glioma
Interventions: RS-fMRI; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 71 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2033
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Neuropathic Pain
Interventions: ASCT-83, Placebo; Drug
Lead sponsor: Alcamena Stem Cell Therapeutics; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 72 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Breast Cancer
Interventions: Individual Sleep Promotion Plan, Healthy Eating Control; Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 19 Years and older
Enrollment: 220 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Type 1 Diabetes (T1D), Sleep Health
Interventions: Sleep Health and Circadian Timing Intervention; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 14 Years to 19 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Peripheral Arterial Disease Below the Knee, Peripheral Arterial Disease, Rutherford 4 and 5 with Possibility to Improve Vascularization
Interventions: Multicath, Standard of Care (SOC); Device
Lead sponsor: Summa Therapeutics, LLC; Industry
Eligibility: 18 Years to 120 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Wilmington, Delaware • Vineland, New Jersey

Conditions: 16P11.2 Deletion Syndrome, 16p11.2 Duplications, 1Q21.1 Deletion, 1Q21.1 Microduplication Syndrome (Disorder), ACTL6B, ADNP, AHDC1, ANK2, ANKRD11, ARID1B, ASH1L, BCL11A, CHAMP1, CHD2, CHD8, CSNK2A1, CTBP1, CTNNB1 Gene Mutation, CUL3, DDX3X, DNMT3A, DSCAM, DYRK1A, FOXP1, GRIN2A, GRIN2B, HIVEP2-Related Intellectual Disability, HNRNPH2, KATNAL2, KDM5B, KDM6B, KMT2C Gene Mutation, KMT2E, KMT5B, MBD5, MED13L, PACS1, PPP2R5D-Related Intellectual Disability, PTCHD1, REST, SCN2A Encephalopathy, SETBP1 Gene Mutation, SETD5, SMARCA4 Gene Mutation, SMARCC2, STXBP1 Encephalopathy With Epilepsy, SYNGAP1-Related Intellectual Disability, TBR1, ARHGEF9, HNRNPU, PPP3CA, PPP2R1A, SLC6A1, 2p16.3 Deletions, 5q35 Deletions, 5q35 Duplications, 7q11.23 Duplications, 15Q13.3 Deletion Syndrome, 16p11.2 Triplications, 16P12.2 Microdeletion, 16P13.11 Microdeletion Syndrome (Disorder), 17Q12 Microdeletion Syndrome (Disorder), 17Q12 Duplication Syndrome, 17Q21.31 Deletion Syndrome, 17q21.3 Duplications, ACTB, ADSL, AFF2, ALDH5A1, ANK3, ARX, ATRX Gene Mutation, AUTS2 Syndrome, BCKDK, BRSK2, CACNA1C, CAPRIN1, CASK, CASZ1, CHD3, CIC, CNOT3, CREBBP Gene Mutation, CSDE1, CTCF, DEAF1, DHCR7, DLG4, EBF3, EHMT1, EP300 Gene Mutation, GIGYF1, GRIN1, GRIN2D, IQSEC2-Related Syndromic Intellectual Disability, IRF2BPL, KANSL1, KCNB1, KDM3B, NEXMIF, KMT2A, MBOAT7, MEIS2, MYT1L, NAA15, NBEA, NCKAP1, NIPBL, NLGN2, NLGN3, NLGN4X, NR4A2, NRXN1, NRXN2, NSD1 Gene Mutation, PHF21A, PHF3, PHIP, PSMD12, RELN, RERE, RFX3, RIMS1, RORB, SCN1A, SETD2 Gene Mutation, SHANK2, SIN3A, SLC9A6, SON, SOX5, SPAST, SRCAP, TAOK1, TANC2, TCF20, TLK2, TRIO, TRIP12, UPF3B, USP9X, VPS13B, WAC, WDFY3, ZBTB20, ZNF292, ZNF462, 2Q37 Deletion Syndrome, 9q34 Duplications, 15q15 Deletions, 15Q24 Deletion, NR3C2, SYNCRIP, 2q37.3 Deletion, 6q16 Deletion, 15q11.2 BP1-BP2 Deletion, 16p13.3 Deletion, 17Q11.2 Microduplication Syndrome (Disorder), 17p13.3, Xq28 Duplication, CLCN4, CSNK2B, DYNC1H1, EIF3F, GNB1, MED13, MEF2C, RALGAPB, SCN1B, YY1, Xp11.22 Duplication, PACS2, MAOA, MAOB, HNRNPC, HNRNPD, HNRNPK, HNRNPR, HNRNPUL2, 5P Deletion Syndrome, TCF7L2 Gene Mutation, HECW2, PPM1D, RNU4-2, SNAP25, FOXP2, ITSN1
Interventions: Not listed
Lead sponsor: Simons Searchlight; Other
Eligibility: Not listed
Enrollment: 100,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2050
U.S. locations: 2
States / cities: Boston, Massachusetts • Lewisburg, Pennsylvania

Conditions: Schizophrenia, Bipolar Disorder
Interventions: SULT4A1-1 genetic test; Genetic
Lead sponsor: Medco Health Solutions, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 1,110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Franklin Lakes, New Jersey

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Personalized Pacing: A New Paradigm for Patients With Diastolic Dysfunction or Heart Failure With Preserved Ejection Fraction

Study of Nutrition in Acute Pancreatitis

Transmagnetic Stimulation Pilot in Primary Progressive Aphasia

SpO2 Accuracy of Noninvasive Disposable Pulse Oximeter Sensor

Myocardial Perfusion Imaging Galmydar Rest/Stress

Indirect Calorimetry-Guided Parenteral Nutrition Prescribing in Oncology Patients

Researching Effective Sleep Treatments (Project REST)

The Feasibility and Examination of the Effects of Floatation-based REST on a Community Sample With PTSD

Feedback, Motor Sequence Learning, and Brain Connectivity

Oxytocin Rest to Reduce Cesarean Delivery

Effects of Nutritional Preconditioning on the Patient's Outcomes After Surgery

Physical Activity and Basal Metabolic Rate in Postmenopausal Women

Study of Resting and Exercising Body Functioning in Freeman-Sheldon Syndrome and Related Conditions

Phenotyping IBS: Perceptions and Modulations of Visceral Sensations

ARMS: The Arm Rest and Support Study

RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)

Intracoronary Bradykinin Mediated t-PA Release in Heart Transplant Recipients

Cognitive Changes of IDH-mutant and IDH-wildtype Glioma Patients After Chemoradiotherapy With Radiation Dose to the Resting State Networks

Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults

Fatigue in Breast Cancer: A Behavioral Sleep Intervention

Type 1 Diabetes REst for Metabolic Health

Below-the-Knee Interventions for Limb Salvage: Use of Multifunctional Angioplasty Balloon Catheters

Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight

Relative Effectiveness of Schizophrenia Therapy Study