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Showing 1–24 of 267 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Radiofrequency Ablation Clear all
Terminated Not applicable Interventional Results available

Atrial Pressure Electrophysiology Pilot Study

NCT01845974
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
ThermoCool® SF NAV Catheter, ThermoCool® catheter
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Sep 5, 2026, 4:03 PM EDT
Terminated No phase listed Observational

Cryoablation Versus Radiofrequency Ablation

NCT00238823
View directory record Official record
Conditions
Congenital Disorders
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 22, 2007 · Synced Sep 5, 2026, 4:03 PM EDT
Completed Not applicable Interventional

Comparison of Treatments for Barrett's Esophagus With High-Grade Dysplasia/Early Adenocarcinoma

NCT01961778
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
Radio-Frequency Ablation, Cryotherapy
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 11, 2022 · Synced Sep 5, 2026, 4:03 PM EDT
Terminated Phase 4 Interventional Results available

Post-lesion Administration of Dexamethasone to Prevent the Development of Neuritis After Radiofrequency Ablation

NCT03247413
View directory record Official record
Conditions
Neuritis, Radiofrequency Ablation
Interventions
Dexamethasone 4 mg/ml, Normal saline
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Sep 5, 2026, 4:03 PM EDT
Recruiting Not applicable Interventional

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

NCT07214376
View directory record Official record
Conditions
Pulmonary Hypertension, Heart Failure With Reduced Ejection Fraction, Hypertension, Vascular Diseases, Cardiovascular Diseases, Heart Failure, Heart Failure With Preserved Ejection Fraction, Heart Failure With Mid Range Ejection Fraction
Interventions
Pulmonary Artery Denervation (PADN), Sham procedure control
Device
Lead sponsor
Pulnovo Medical, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
6
States / cities
Tucson, Arizona • Houma, Louisiana • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 5, 2026, 4:03 PM EDT
Completed Not applicable Interventional

Radiofrequency Ablation of Papillary Thyroid Microcarcinoma

NCT05132205
View directory record Official record
Conditions
Papillary Thyroid Cancer
Interventions
Radiofrequency Ablation
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Sep 5, 2026, 4:03 PM EDT
Completed No phase listed Observational

Radiofrequency Nerve Ablation Versus Sham to Treat Chronic Low Back Pain Caused by Sacroiliac Joint Dysfunction

NCT01104051
View directory record Official record
Conditions
Sacroiliac Joint Dysfunction
Interventions
Not listed
Lead sponsor
Coastal Orthopedics & Sports Medicine
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Jul 28, 2015 · Synced Sep 5, 2026, 4:03 PM EDT
Completed Not applicable Interventional Results available

CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF)

NCT01984346
View directory record Official record
Conditions
Persistent Atrial Fibrillation
Interventions
AtriCure EPi-Sense-AF Guided Coagulation System with VisiTrax, Endocardial RF Catheter ablation using Open Irrigated-tip RF Abaltion Catheter with unidirectional or bidirectional steering
Device
Lead sponsor
AtriCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
25
States / cities
Birmingham, Alabama • Huntsville, Alabama • Denver, Colorado + 22 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Sep 5, 2026, 4:03 PM EDT
Completed Phase 3 Interventional Results available

First Line Radiofrequency Ablation Versus Antiarrhythmic Drugs for Atrial Fibrillation Treatment (The RAAFT Study)

NCT00392054
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Pulmonary Vein Isolation performed by Catheter Ablation, Conventional Antiarrhythmic Drug Therapy
Procedure · Drug
Lead sponsor
Population Health Research Institute
Other
Eligibility
19 Years to 75 Years
Enrollment
127 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 30, 2020 · Synced Sep 5, 2026, 4:03 PM EDT
Completed Phase 4 Interventional Results available

Corticosteroid Pulse After Ablation

NCT00807586
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Solumedrol, Placebo
Drug
Lead sponsor
Minneapolis Heart Institute Foundation
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Sep 5, 2026, 4:03 PM EDT
Recruiting No phase listed Observational

Safety and Efficacy of Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA) in the Treatment of Pancreatic Lesions

NCT07737171
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA)
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
60 participants
Timeline
2026 – 2033
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2026 · Synced Sep 5, 2026, 4:03 PM EDT
Completed Phase 4 Interventional Results available

Medical Therapy Versus Radiofrequency Endometrial Ablation in the Initial Treatment of Menorrhagia

NCT01165307
View directory record Official record
Conditions
Menorrhagia
Interventions
Estradiol 30mcg / Levonorgestrel 150mcg monophasic oral contraceptive pills, Naproxen sodium pills, NovaSure® Radiofrequency Endometrial Ablation
Drug · Device
Lead sponsor
Abimbola Famuyide
Other
Eligibility
30 Years to 55 Years · Female only
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 19, 2017 · Synced Sep 5, 2026, 4:03 PM EDT
Completed Not applicable Interventional

MRI-Targeted Focal Ablation of the Prostate in Men With Prostate Cancer

NCT02303054
View directory record Official record
Conditions
Prostate Cancer
Interventions
Bipolar Radiofrequency Focal Ablation
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
40 Years to 80 Years · Male only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 10, 2017 · Synced Sep 5, 2026, 4:03 PM EDT
Recruiting Not applicable Interventional

RFA Using Multi-Tined Electrodes vs.Traditional Electrodes for Lumbar Spondylosis

NCT06477094
View directory record Official record
Conditions
Lumbar Spondylosis
Interventions
Stratus Nimbus Electrosurgical RF Multi-Tined Expandable Electrode, Stryker Venom Radiofrequency Cannula
Device
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 5, 2026, 4:03 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Cooled RF Lesion MRI Characteristics

NCT03631030
View directory record Official record
Conditions
Arthritis;Lumbosacral, Osteo Arthritis Knee, Sacroiliitis, Hip Osteoarthritis, Arthritis, Degenerative
Interventions
Cooled radiofrequency ablation
Device
Lead sponsor
International Spine, Pain and Performance Center
Other
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 6, 2019 · Synced Sep 5, 2026, 4:03 PM EDT
Recruiting Not applicable Interventional

VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain

NCT06336447
View directory record Official record
Conditions
Pain, Chronic
Interventions
Experimental: Group #1: Virtual Reality Headset, Group 2 No Virtual Reality Headset
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Sep 5, 2026, 4:03 PM EDT
Completed No phase listed Observational Results available

A Study to Evaluate the Effectiveness of Essure Post-NovaSure Radiofrequency Endometrial Ablation Procedure Following a Successful Essure Confirmation Test

NCT01740687
View directory record Official record
Conditions
Contraception, Menorrhagia
Interventions
ESS305 (Essure, BAY1454032), NovaSure
Device · Procedure
Lead sponsor
Bayer
Industry
Eligibility
21 Years to 50 Years · Female only
Enrollment
211 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
17
States / cities
Aurora, Colorado • Ocala, Florida • Decatur, Illinois + 14 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2023 · Synced Sep 5, 2026, 4:03 PM EDT
Recruiting Not applicable Interventional

A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1 Study)

NCT07355270
View directory record Official record
Conditions
Type-2 Diabetes Mellitus
Interventions
RF Vapor Ablation
Device
Lead sponsor
Aqua Medical, Inc.
Industry
Eligibility
22 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
4
States / cities
Scottsdale, Arizona • Newport Beach, California • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 5, 2026, 4:03 PM EDT
Completed No phase listed Observational

Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter Registry.

NCT04937322
View directory record Official record
Conditions
Bile Duct Cancer, Pancreas Cancer
Interventions
Interventional Endoscopy procedures
Procedure
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 10, 2021 · Synced Sep 5, 2026, 4:03 PM EDT
Completed Not applicable Interventional

Genicular Radiofrequency Ablation Efficacy in Achieving Total Knee Pain Reduction Trial

NCT02947321
View directory record Official record
Conditions
Knee Arthroplasty, Total, Osteoarthritis, Radiologic Tibiofemoral Osteoarthritis
Interventions
Genicular Nerve RFA, Sham Genicular Nerve RFA
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
45 Years to 79 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 4, 2020 · Synced Sep 5, 2026, 4:03 PM EDT
Completed Phase 2 Interventional Results available

Sorafenib Therapy Prior to Radiofrequency Ablation for Intermediate Sized Hepatocellular Cancer

NCT00813293
View directory record Official record
Conditions
Hepatocellular Cancer
Interventions
Sorafenib, radiofrequency ablation
Drug · Procedure
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 12, 2023 · Synced Sep 5, 2026, 4:03 PM EDT
Terminated Not applicable Interventional

Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid Nodule

NCT05003856
View directory record Official record
Conditions
Benign Thyroid Gland Neoplasm, Recurrent Thyroid Gland Carcinoma, Thyroid Gland Follicular Tumor of Uncertain Malignant Potential, Thyroid Gland Nodule, Thyroid Gland Papillary Carcinoma
Interventions
Quality-of-Life Assessment, Radiofrequency Ablation
Other · Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Sep 5, 2026, 4:03 PM EDT
Recruiting Not applicable Interventional

Brief Mindfulness Intervention for Pain Before an In-clinic Orthopedic Procedure

NCT06471075
View directory record Official record
Conditions
Pain, Chronic Pain, Acute Pain
Interventions
Mindful Pain Management, Pain Psychoeducation
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 3, 2025 · Synced Sep 5, 2026, 4:03 PM EDT
Completed Phase 2 Interventional

Magnetic Resonance Imaging-guided Thermal Radiofrequencey Ablation of Primary Renal Cell Carcinoma, Hepatic Metastasis, and Other Sites of Solid Organ Tumor and Metastases

NCT00006255
View directory record Official record
Conditions
Kidney Cancer, Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
radiofrequency ablation, thermal ablation therapy
Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 10, 2010 · Synced Sep 5, 2026, 4:03 PM EDT