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Showing 1–24 of 621 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Completed Not applicable Interventional Results available

Comparison of New Contact Lens With Current Marketed Lens

NCT03360110
Conditions
Myopia
Interventions
Phoebe test lens, stenfilcon A lens (control)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Product Performance Evaluation of a Novel Contact Lens for Daily Disposable Use

NCT00784641
Conditions
Myopia
Interventions
Novel Bausch & Lomb daily disposable contact lenses, Bausch & Lomb SofLens daily disposable contact lenses., Johnson and Johnson 1-Day Acuvue Moist contact lenses
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
567 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Rochester, New York
Not listed Phase 3 Interventional Accepts healthy volunteers

Investigation of the Presbia Flexivue Microlens™

NCT02110472
Conditions
Presbyopia
Interventions
Corneal inlay
Device
Lead sponsor
PresbiBio, LLC
Industry
Eligibility
45 Years to 60 Years
Enrollment
412 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
11
States / cities
Beverly Hills, California • La Jolla, California • Los Angeles, California + 8 more
Conditions
Myopia
Interventions
Test lens, control lens
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
77 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
4
States / cities
San Diego, California • Whittier, California • Sarasota, Florida + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Evaluation of Acuity 200 (Fluoroxyfocon A) RGP Contact Lens

NCT03971227
Conditions
Refractive Errors
Interventions
Acuity 200 (Fluoroxyfocon A) contact lens, Acuity 100 (Hexafocon A) contact lens
Device
Lead sponsor
Acuity Polymers, Inc.
Industry
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
3
States / cities
Honolulu, Hawaii • Edina, Minnesota • Pittsford, New York
Conditions
Refractive Errors
Interventions
AR Eyeglasses first, SR Eyeglasses second, SR Eyeglasses first, AR Eyeglasses second
Other
Lead sponsor
PlenOptika, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Corneal Astigmatism Measurement Study

NCT00818532
Conditions
Astigmatism
Interventions
Not listed
Lead sponsor
Alcon Research
Industry
Eligibility
50 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Astigmatism
Interventions
Clareon Vivity Extended Vision IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
3
States / cities
Bloomfield Hills, Michigan • Dallas, Texas • Sugar Land, Texas
Conditions
Cataract, Refractive Error, Low Vision
Interventions
Visual impairment intervention program
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
2,544 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2002
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Presbyopia
Interventions
Raindrop Near Vision Inlay
Device
Lead sponsor
Whitten Laser Eye
Other
Eligibility
40 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Conditions
Cataract, Presbyopia, Posterior Capsule Opacification
Interventions
Not listed
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
22 Years and older
Enrollment
435 participants
Timeline
2023 – 2027
U.S. locations
14
States / cities
Dothan, Alabama • Newport Beach, California • Cape Coral, Florida + 11 more
Completed No phase listed Observational Accepts healthy volunteers

Post-approval Follow-up Study of the IC-8 Apthera Intraocular Lens (IOL)

NCT05758883
Conditions
Cataract, Presbyopia
Interventions
Not listed
Lead sponsor
AcuFocus, Inc.
Industry
Eligibility
22 Years and older
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
20
States / cities
Tucson, Arizona • Bakersfield, California • Laguna Hills, California + 17 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of a New Silicone Hydrogel Contact Lens

NCT01309880
Conditions
Myopia
Interventions
Test lens, Air Optix Aqua
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, New York
Conditions
Refractive Errors
Interventions
Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
5
States / cities
Maitland, Florida • Medina, Minnesota • Granville, Ohio + 2 more
Conditions
Nearsightedness, Near Sightedness, Near-sightedness
Interventions
SYD-101 0.01%, SYD-101 0.03%, Vehicle
Drug
Lead sponsor
Sydnexis, Inc.
Industry
Eligibility
3 Years to 14 Years
Enrollment
852 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
41
States / cities
Irwindale, California • Pasadena, California • San Diego, California + 35 more
Conditions
Myopia
Interventions
omafilcon A, etafilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
4
States / cities
Phoenix, Arizona • Lake Zurich, Illinois • Athens, Ohio + 1 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Two Toric Contact Lenses on Current Toric Wearers

NCT00639379
Conditions
Ametropia
Interventions
senofilcon A toric, alphafilcon A toric
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
7
States / cities
Jacksonville, Florida • Orlando, Florida • Morrow, Georgia + 4 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy in Controlling Myopia in Young Children Using a Novel Spectacle Lens

NCT06034327
Conditions
Myopia, Juvenile Myopia, Myopia Progression
Interventions
Single vision, impact-resistant spectacle lenses; Test Arm, Single vision, impact-resistant spectacle lenses; Control Arm
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 8 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
14
States / cities
Oakland, California • San Diego, California • San Francisco, California + 11 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Clinical Trial to Evaluate a Corneal Inlay for the Improvement of Near Vision in Presbyopic Patients

NCT01373580
Conditions
Presbyopia
Interventions
The Raindrop Near Vision Inlay
Device
Lead sponsor
ReVision Optics, Inc.
Industry
Eligibility
35 Years to 65 Years
Enrollment
373 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
11
States / cities
Camarillo, California • Laguna Hills, California • Newport Beach, California + 7 more
Conditions
Refractive Errors, Astigmatism
Interventions
Verofilcon A toric contact lenses, Stenfilcon A toric contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
6
States / cities
Maitland, Florida • Pittsburg, Kansas • Sterling Heights, Michigan + 3 more
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Side Effects of Atropine (SEA) Study

NCT03593044
Conditions
Myopia
Interventions
0.01% concentration atropine drops
Drug
Lead sponsor
Jeffrey J. Walline, OD PhD
Other
Eligibility
21 Years to 30 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Astigmatism
Interventions
verofilcon A toric contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Fort Worth, Texas
Conditions
Presbyopia
Interventions
AGN-199201 ophthalmic solution, AGN-190584 ophthalmic solution, AGN-190584 vehicle, AGN-199201 + AGN-190584 Combination, AGN-199201 vehicle
Drug
Lead sponsor
Allergan
Industry
Eligibility
40 Years to 50 Years
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
20
States / cities
Artesia, California • Azusa, California • Costa Mesa, California + 17 more