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ClinicalTrials.gov public records Last synced May 22, 2026, 5:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Refractive Errors Clear all
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Aphakia, Astigmatism, Presbyopia
Interventions
Clareon Vivity IOL - Non Toric, Clareon Vivity IOL - Toric, Clareon PanOptix Trifocal IOL - Non Toric, Clareon PanOptix Trifocal IOL - Toric
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
6
States / cities
Torrance, California • Jacksonville, Florida • Liverpool, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced May 22, 2026, 5:05 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Myopia
Interventions
NeuroVision's NVC treatment for Low Myopia
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 59 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced May 22, 2026, 5:05 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Presbyopia
Interventions
omafilcon A / PC 1-D MF, lotrafilcon B / Air Optix MF
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
40 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 6, 2014 · Synced May 22, 2026, 5:05 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Myopia
Interventions
Orthokeratology
Device
Lead sponsor
Art Optical Contact Lens, Inc.
Industry
Eligibility
21 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced May 22, 2026, 5:05 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Presbyopia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Johns Creek, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 25, 2024 · Synced May 22, 2026, 5:05 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Aphakia, Presbyopia, Astigmatism
Interventions
ACRYSOF IQ RESTOR +3.0 Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal Toric IOL, ACRYSOF IQ RESTOR +2.5 D Multifocal IOL, Cataract Surgery
Device · Procedure
Lead sponsor
Alcon Research
Industry
Eligibility
22 Years and older
Enrollment
2,449 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
37
States / cities
Dothan, Alabama • Phoenix, Arizona • Fresno, California + 32 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced May 22, 2026, 5:05 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Myopia
Interventions
Single vision contact lenses, Multifocal contact lenses
Device
Lead sponsor
Visioneering Technologies, Inc
Industry
Eligibility
7 Years to 13 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
4
States / cities
Fresno, California • Deerfield, Illinois • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced May 22, 2026, 5:05 AM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Presbyopia
Interventions
CSF-1, CSF-1 Component #1, CSF-1 Component #2
Drug
Lead sponsor
Orasis Pharmaceuticals Ltd.
Industry
Eligibility
45 Years to 64 Years
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
7
States / cities
Newport Beach, California • Littleton, Colorado • Andover, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced May 22, 2026, 5:05 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Presbyopia
Interventions
BRIMOCHOL™ PF, Carbachol PF, Brimonidine tartrate
Drug
Lead sponsor
Visus Therapeutics
Other
Eligibility
45 Years to 80 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
15
States / cities
Glendale, California • Rancho Cordova, California • Jacksonville, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 14, 2024 · Synced May 22, 2026, 5:05 AM EDT
Suspended Phase 2 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Axial Myopia, Refractive Errors
Interventions
Oral Riboflavin
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
6 Years to 12 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2030
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2024 · Synced May 22, 2026, 5:05 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Myopia
Interventions
Delefilcon A contact lenses, Senofilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
4
States / cities
Bloomington, Illinois • Pittsburg, Kansas • Powell, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 4, 2019 · Synced May 22, 2026, 5:05 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Myopia, Cornea
Interventions
Euclid orthokeratology MAX (current design), Euclid orthokeratology MAX Phoenix (new design)
Device
Lead sponsor
Euclid Systems Corporation
Industry
Eligibility
6 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
5
States / cities
Costa Mesa, California • Saint Johns, Florida • Edina, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2024 · Synced May 22, 2026, 5:05 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Myopia
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
1 Month and older
Enrollment
7,477 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 12, 2020 · Synced May 22, 2026, 5:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Visual Acuity, Astigmatism, Anisometropia
Interventions
LFR-260 portable phoropter, Traditional phoropter (SOC)
Device
Lead sponsor
Evolution Optiks Limited
Industry
Eligibility
12 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Worcester, Massachusetts • Oyster Bay, New York
Source: ClinicalTrials.gov public record
Updated Sep 24, 2024 · Synced May 22, 2026, 5:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Myopia
Interventions
Investigational Lens, Air Optix Aqua lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 23, 2014 · Synced May 22, 2026, 5:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Myopia
Interventions
comfilcon A sphere lens (control), comfilcon A asphere lens (test)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 34 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
4
States / cities
Whittier, California • Medina, Minnesota • Vestal, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced May 22, 2026, 5:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Presbyopia, Myopia, Hyperopia, Astigmatism
Interventions
APIOC for Presbyopia and APIOC for Presbyopia for Astigmatism
Device
Lead sponsor
Lentechs, LLC
Industry
Eligibility
40 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
6
States / cities
San Diego, California • Orlando, Florida • Lexington, Kentucky + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced May 22, 2026, 5:05 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Myopia
Interventions
Atropine Sulfate 1% Oph Soln
Drug
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 40 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 14, 2018 · Synced May 22, 2026, 5:05 AM EDT
Terminated Not applicable Interventional Results available
View directory record Official record
Conditions
Presbyopia
Interventions
Raindrop Near Vision Inlay
Device
Lead sponsor
Eye Center of North Florida
Other
Eligibility
41 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Panama City, Florida
Source: ClinicalTrials.gov public record
Updated Aug 9, 2020 · Synced May 22, 2026, 5:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Myopia
Interventions
Control Contact Lens (stenfilcon A), Test Contact Lens (senofilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
3
States / cities
Ocoee, Florida • Vestal, New York • Granville, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced May 22, 2026, 5:05 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Cornea; Ectasia, Refractive Errors, Keratoconus
Interventions
Optical coherence tomography
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
16 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced May 22, 2026, 5:05 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Myopia
Interventions
Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
8 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced May 22, 2026, 5:05 AM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Hyperopia
Interventions
Acuvue Advance Plus, Acuvue Advance
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
3
States / cities
Winter Park, Florida • New York, New York • Nanticoke, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced May 22, 2026, 5:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Myopia
Interventions
Epi-Lasik
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 15, 2010 · Synced May 22, 2026, 5:05 AM EDT