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Showing 25–48 of 633 matching trials from the live ClinicalTrials.gov search.
Conditions
Myopia, Hyperopia
Interventions
narafilcon B daily disposable soft contact lenses, etafilcon A daily disposable soft contact lenses
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
8 Years and older
Enrollment
1,171 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
37
States / cities
Campbell, California • Fullerton, California • Huntington Beach, California + 29 more
Conditions
Refractive Errors, Myopia
Interventions
Verofilcon A contact lenses, Somofilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
4
States / cities
Maitland, Florida • Medina, Minnesota • Powell, Ohio + 1 more
Active, not recruiting Not applicable Interventional

LASIK iDesign vs SMILE

NCT07126756
Conditions
Myopia, Astigmatism
Interventions
STAR S4 IR Excimer Laser System, VisuMax 400 Surgical Laser
Device
Lead sponsor
59th Medical Wing
Federal
Eligibility
21 Years to 50 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Lackland Air Force Base, Texas
Conditions
Myopia
Interventions
Test Contact Lens, Nelfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Phase 4 Interventional Accepts healthy volunteers

The Influence of Atropine on Choroidal Thickness

NCT03158142
Conditions
Myopia
Interventions
Atropine Sulfate 1% Oph Soln
Drug
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
18 Years to 40 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New York, New York
Conditions
Myopia, Astigmatism
Interventions
Ray-Tracing Guided LASIK, Keratorefractive Lenticule Extraction (KLEx), WaveFront Optimized LASIK, Topography Guided LASIK
Device
Lead sponsor
Hoopes Vision
Other
Eligibility
22 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Draper, Utah
Completed Not applicable Interventional Results available

DD T2 Daily Disposable Registration Trial

NCT03305770
Conditions
Myopia, Refractive Errors
Interventions
verofilcon A contact lenses, delefilcon A contact lenses
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
6
States / cities
San Diego, California • Longwood, Florida • Maitland, Florida + 3 more
Completed No phase listed Observational

Smart Autofocusing Eyeglasses

NCT03911596
Conditions
Presbyopia
Interventions
Smart Autofocusing Eyeglasses
Device
Lead sponsor
University of Utah
Other
Eligibility
45 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed Not applicable Interventional Results available

Evaluation of Delefilcon A Contact Lenses

NCT06884202
Conditions
Refractive Errors, Myopia
Interventions
Delefilcon A contact lenses with different base curves and diameters, Delefilcon A contact lenses with standard base curves and diameters
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
16
States / cities
Los Angeles, California • Oakland, California • San Francisco, California + 13 more
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of the Bausch & Lomb PureVision Under Nighttime Driving Conditions

NCT00581659
Conditions
Astigmatism
Interventions
Not listed
Lead sponsor
University of Iowa
Other
Eligibility
25 Years to 45 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Refractive Ametropia
Interventions
Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
Device
Lead sponsor
Alcon Research
Industry
Eligibility
40 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Johns Creek, Georgia
Conditions
Myopia
Interventions
O2Optix contact lens, Proclear contact lens, ReNu MultiPlus Multi-Purpose Solution, Clear Care Cleaning and Disinfecting Solution
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years and older
Enrollment
473 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
25
States / cities
North Little Rock, Arkansas • Campbell, California • Cupertino, California + 22 more
Completed Not applicable Interventional Accepts healthy volunteers

Bifocal Contact Lens Study for Adults With Age-Related Near Vision Loss

NCT03653715
Conditions
Presbyopia
Interventions
Clerio Vision LIRIC-modified Bifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Multifocal Contact Lens, Johnson & Johnson 1-Day Acuvue Moist Contact Lens, Clerio Vision Single Vision Contact Lens
Device
Lead sponsor
Clerio Vision, Inc.
Industry
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Rochester, New York
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Control of Myopia Using Novel Spectacle Lens Designs

NCT03623074
Conditions
Juvenile Myopia
Interventions
Novel spectacle lens design, Spectacle lenses
Device
Lead sponsor
SightGlass Vision, Inc.
Industry
Eligibility
6 Years to 10 Years
Enrollment
266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2026
U.S. locations
13
States / cities
Whittier, California • Longwood, Florida • Pensacola, Florida + 10 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

1-Week Dispensing Evaluation of Kalifilcon A Toric Contact Lenses Compared to Ultra for Astigmatism

NCT05320042
Conditions
Myopia, Astigmatism
Interventions
kalifilcon A daily disposable toric contact lenses, Ultra for Astigmatism (samfilcon A) contact lenses
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Rochester, New York
Conditions
Myopia
Interventions
comfilcon A, samfilcon A
Device
Lead sponsor
CooperVision, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Whittier, California • Medina, Minnesota
Conditions
Presbyopia
Interventions
Pilocarpine Ophthalmic Topical Cream, Dose 1, Pilocarpine Ophthalmic Topical Cream, Dose 2, Pilocarpine Ophthalmic Topical Cream, Dose 3, Placebo Ophthalmic Topical Cream
Drug
Lead sponsor
Glaukos Corporation
Industry
Eligibility
40 Years to 55 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
10
States / cities
Chandler, Arizona • Sun City, Arizona • Glendale, California + 7 more
Completed Not applicable Interventional Results available

Conventional Surgery vs. Verion/VerifEye

NCT02513745
Conditions
Cataract, Astigmatism
Interventions
Conventional, Refractive Cataract Suite (Verion + ORA)
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
50 Years and older
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Conditions
Myopia, Accommodation
Interventions
Multifocal soft contact lenses
Device
Lead sponsor
State University of New York College of Optometry
Other
Eligibility
8 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Conditions
Presbyopia
Interventions
LD118033 contact lens, PureVision multifocal contact lens
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Rochester, New York
Completed Not applicable Interventional Accepts healthy volunteers

High Resolution Wavefront-guided vs. Wavefront Optimized LASIK

NCT02565537
Conditions
Nearsightedness, Astigmatism
Interventions
LASIK
Procedure
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Completed Not applicable Interventional Accepts healthy volunteers

T30 for Astigmatism in Digital Device Users

NCT06266728
Conditions
Contact Lens Complication, Astigmatism, Refractive Errors
Interventions
Total30 for Astigmatism Contact Lenses
Device
Lead sponsor
Southern College of Optometry
Other
Eligibility
18 Years to 40 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
2
States / cities
Pittsburg, Kansas • Coldwater, Mississippi
Completed Not applicable Interventional Results available

Post-Approval Study of the TECNIS SYMFONY® Toric Lenses

NCT03791619
Conditions
Cataract, Corneal Astigmatism
Interventions
Higher Cylinder Toric IOL, Lower Cylinder Toric IOL
Device
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
22 Years and older
Enrollment
475 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
23
States / cities
Bakersfield, California • Long Beach, California • Santa Monica, California + 18 more