- Conditions
- Mitral Valve Insufficiency, Heart Failure
- Interventions
- Surgical mitral valvuloplasty with placement of annular ring (SMVR), Optimal medical therapy (OMT)
- Procedure · Drug
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 8
- States / cities
- Atlanta, Georgia • Boston, Massachusetts • Minneapolis, Minnesota + 5 more
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
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matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Aortic Valve Stenosis, Aortic Valve Stenosis With Insufficiency, Regurgitation, Aortic Valve, Aortic Valve Incompetence
- Interventions
- EDWARDS INTUITY valve
- Device
- Lead sponsor
- Edwards Lifesciences
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 934 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2021
- U.S. locations
- 29
- States / cities
- Los Angeles, California • Newport Beach, California • Palo Alto, California + 24 more
- Conditions
- Mitral Valve Regurgitation
- Interventions
- MitraClip™ device implantation, Mitral Valve Repair Surgery
- Device · Procedure
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2035
- U.S. locations
- 63
- States / cities
- Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 47 more
- Conditions
- Mitral Valve (MV) Regurgitation
- Interventions
- TRANSOM
- Device
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 21 Years and older
- Enrollment
- 175 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2029
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Valve Disease, Aortic, Mitral Regurgitation (MR), Aortic Stenosis, Valvular Heart Disease, Tricuspid Regurgitation (TR), Aortic Regurgitation
- Interventions
- Not listed
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Tricuspid Valve Regurgitation, Non-rheumatic, Mitral Valve Regurgitation
- Interventions
- Not listed
- Lead sponsor
- Medical College of Wisconsin
- Other
- Eligibility
- Not listed
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2019
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Mitral Valve Insufficiency, Mitral Valve Regurgitation, Mitral Valve Incompetence, Mitral Regurgitation, Mitral Insufficiency
- Interventions
- MitraClip® implant
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 965 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2018
- U.S. locations
- 38
- States / cities
- Los Angeles, California • Mountain View, California • Sacramento, California + 31 more
- Conditions
- Tricuspid Regurgitation, Tricuspid Valve Disease
- Interventions
- TricValve® Transcatheter Bicaval Valve System
- Device
- Lead sponsor
- P+F Products + Features USA Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 36
- States / cities
- Phoenix, Arizona • Tucson, Arizona • San Diego, California + 31 more
- Conditions
- GERD, Acid Reflux Disease, Heartburn, Regurgitation
- Interventions
- AZD3355, Placebo, Gelusil®
- Drug
- Lead sponsor
- AstraZeneca
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 478 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 84
- States / cities
- Athens, Alabama • Tucson, Arizona • Little Rock, Arkansas + 81 more
- Conditions
- Tricuspid Regurgitation
- Interventions
- Transcatheter Tricuspid Valve Replacement
- Device
- Lead sponsor
- Trisol Medical
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2031
- U.S. locations
- 7
- States / cities
- Los Angeles, California • Atlanta, Georgia • New York, New York + 4 more
- Conditions
- Atrial Fibrillation (AF), Mitral Valve (MV) Regurgitation
- Interventions
- Left Atrial Appendage Occlusion, Mitral Valve Transcatheter Edge to Edge Repair
- Device
- Lead sponsor
- EchoPixel, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Paravalvular Aortic Regurgitation
- Interventions
- AVP III
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2026
- U.S. locations
- 14
- States / cities
- Birmingham, Alabama • Atlanta, Georgia • Boston, Massachusetts + 10 more
- Conditions
- Heart Failure and Reduced Ejection Fraction, Functional Mitral Regurgitation
- Interventions
- Cardiac MRI
- Diagnostic Test
- Lead sponsor
- Minneapolis Heart Institute Foundation
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 125 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 5
- States / cities
- Minneapolis, Minnesota • Charlotte, North Carolina • Cincinnati, Ohio + 2 more
- Conditions
- Aortic Valve Insufficiency, Aortic Valve Regurgitation, Aortic Valve Stenosis, Aortic Valve Incompetence
- Interventions
- Trifecta™ Valve
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 329 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2019
- U.S. locations
- 9
- States / cities
- Los Angeles, California • Minneapolis, Minnesota • Rochester, Minnesota + 6 more
- Conditions
- GERD (Gastroesophageal Reflux Disease)
- Interventions
- eGERD device, eGERD_Sham
- Device
- Lead sponsor
- Gerd Care Medical Ltd
- Industry
- Eligibility
- 22 Years to 75 Years
- Enrollment
- 84 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Heart Failure With Reduced Ejection Fraction, Mitral Regurgitation
- Interventions
- CardioMEMS
- Device
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2030
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Heart Failure, Cardiomyopathy, Dilated
- Interventions
- AccuCinch® Ventricular Restoration System
- Device
- Lead sponsor
- Ancora Heart, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2024
- U.S. locations
- 19
- States / cities
- San Francisco, California • Atlanta, Georgia • Louisville, Kentucky + 15 more
- Conditions
- Mitral Regurgitation, Tricuspid Regurgitation, Valvular Heart Disease
- Interventions
- Abbott SJM Rigid Saddle Ring, Abbott SJM Séguin Ring, Abbott SJM Tailor Ring, Abbott SJM Tailor Band
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 550 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2031
- U.S. locations
- 2
- States / cities
- Durham, North Carolina • Madison, Wisconsin
- Conditions
- Gastroesophageal Reflux Disease
- Interventions
- Rabeprazole 20mg, placebo dinner and bedtime, Rabeprazole 20 mg two times, Placebo at bedtime, Rabeprazole 20mg,placebo dinner ,Low dose Tricyclic Antidepressant
- Drug
- Lead sponsor
- US Department of Veterans Affairs
- Federal
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 236 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2011
- U.S. locations
- 1
- States / cities
- Tucson, Arizona
- Conditions
- Mitral Valve Regurgitation
- Interventions
- Mitral valve replacement
- Device
- Lead sponsor
- Shockwave Medical, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2024
- U.S. locations
- 6
- States / cities
- Los Angeles, California • Chicago, Illinois • Detroit, Michigan + 3 more
- Conditions
- Mitral Regurgitation
- Interventions
- Cephea Mitral Valve System
- Device
- Lead sponsor
- Abbott Medical Devices
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2031
- U.S. locations
- 20
- States / cities
- Phoenix, Arizona • Los Angeles, California • Sacramento, California + 15 more
- Conditions
- Mitral Valve Regurgitation, Left Ventricular Dysfunction, Heart Failure, Mitral Insufficiency, Mitral Incompetence, Ischemic Heart Disease
- Interventions
- Percutaneous mitral valve repair
- Device
- Lead sponsor
- Myocor
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 4
- States / cities
- Atlanta, Georgia • Evanston, Illinois • Shawnee Mission, Kansas + 1 more
- Conditions
- Dysphagia
- Interventions
- Not listed
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Valvular Heart Disease
- Interventions
- Not listed
- Lead sponsor
- Montefiore Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 330,570 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2019
- U.S. locations
- 1
- States / cities
- The Bronx, New York