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Showing 1–24 of 34 matching trials from the live ClinicalTrials.gov search.
Completed Phase 1 Interventional Accepts healthy volunteers

The Autonomic Nervous System and Obesity

NCT00179023
Conditions
OBESITY, HYPERTENSION, PURE AUTONOMIC FAILURE, SHY-DRAGER SYNDROME
Interventions
Trimethaphan, Pseudoephedrine
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 80 Years
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Mirabegron and Physiological Function in Cold Environments

NCT04766021
Conditions
Resting Energy Expenditure, Thermogenesis, Brown Adipose Tissue
Interventions
Mirabegron, Placebo
Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Bloomington, Indiana
Conditions
None Volunteer
Interventions
A novel, proprietary encapsulated form of Capsicum extract in beadlet form standardized to 2% capsaicinoids
Dietary Supplement
Lead sponsor
Hofstra University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Hempstead, New York
Conditions
Menstrual Irregularity
Interventions
EAMD+Calories
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
233 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2014
U.S. locations
1
States / cities
University Park, Pennsylvania
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Overnight Low Oxygen Exposure on Energy Balance

NCT04151927
Conditions
Resting Metabolic Rate, Appetite, Heart Rate Variability
Interventions
Normobaric Hypoxia, Normobaric Normoxia
Device
Lead sponsor
Florida State University
Other
Eligibility
20 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Tallahassee, Florida
Conditions
Malnutitrion, Cancer
Interventions
Indirect Calorimeter, Weight-Based Parenteral Nutrition Dosing
Device · Dietary Supplement
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Weight Loss, Weight Change
Interventions
Follow-up post-bariatric surgery
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
1
States / cities
New York, New York
Conditions
Cystic Fibrosis
Interventions
Daily calorie target based on resting energy expenditure
Other
Lead sponsor
CAMC Health System
Other
Eligibility
6 Years to 99 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Charleston, West Virginia
Completed No phase listed Observational Accepts healthy volunteers

Metabolic Effects of Differential Organ Growth Rates

NCT03219229
Conditions
Resting Energy Expenditure
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
7 Years to 11 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Physical Activity and Basal Metabolic Rate in Postmenopausal Women

NCT01550536
Conditions
Postmenopausal Metabolic Health
Interventions
Resistance and aerobic exercise
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 120 Years · Female only
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
3
States / cities
La Jolla, California • San Diego, California
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Nutritional Preconditioning on the Patient's Outcomes After Surgery

NCT03692507
Conditions
Major Abdominal/GI Surgery
Interventions
HMB, Protein and HMB, ERAS
Dietary Supplement
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Fresno, California
Conditions
Resistance Exercise Performance, Cognitive Functions, Anaerobic Performance, Dietary Supplementation Athletic Performance
Interventions
Low-dose Ashwagandha Supplement, High-dose Ashwagandha Supplement, Maltodextrin (Placebo)
Dietary Supplement
Lead sponsor
Jacksonville State University
Other
Eligibility
18 Years to 40 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Jacksonville, Alabama
Conditions
Decubitis Ulcer
Interventions
Indirect Calorimetry
Procedure
Lead sponsor
Paul Edwards
Other
Eligibility
19 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Lincoln, Nebraska
Completed Not applicable Interventional Accepts healthy volunteers

Influence of Flavonoids and Caffeine Supplementation on Resting Metabolism

NCT03752125
Conditions
Diet Modification
Interventions
Flavonoid, caffeine, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
20 Years to 47 Years · Female only
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kannapolis, North Carolina
Not listed Not applicable Interventional Accepts healthy volunteers

Capsaicin Energy Expenditure and Glucose Metabolism

NCT03859583
Conditions
Obesity, Insulin Resistance
Interventions
Capsaicin, Control
Dietary Supplement
Lead sponsor
George Mason University
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fairfax, Virginia
Conditions
Overweight and Obesity, Weight Loss Maintenance, Dietary Habits
Interventions
Weight Loss Maintenance (Control vs. Reverse Diet)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Completed Not applicable Interventional Accepts healthy volunteers

Time Restricted Feeding in Male Runners

NCT03569852
Conditions
Fasting, Intermittent Fasting, Athletic Performance, Cardiovascular Risk Factor, Resting Energy Expenditure
Interventions
Time Restrictive Feeding, Traditional Eating Pattern
Behavioral
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
20 Years to 40 Years · Male only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Davis, California
Conditions
Morbid Obesity
Interventions
Ephedrine sulfate with caffeine, cellulose
Drug
Lead sponsor
Oregon Weight Loss Surgery, LLC
Other
Eligibility
18 Years to 70 Years
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Beaverton, Oregon • Portland, Oregon
Conditions
Graft-Versus-Host Disease
Interventions
Not listed
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
7 Years to 30 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Resting Metabolic Rate, Energy Metabolism, Haptic Technology, Vibrotactile Stimulation
Interventions
IGNITE Patch (Active), Inactive patch
Device
Lead sponsor
SuperPatch Limited LLC
Industry
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tyrone, Georgia
Conditions
Bladder Cancer
Interventions
Not listed
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Obesity
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
6 Years and older
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Terminated Not applicable Interventional Accepts healthy volunteers

Energy Expenditure and Substrate Oxidation in a Whole Room Calorimeter

NCT04061369
Conditions
Overweight, Obesity, Body Weight
Interventions
Low fat meal, Moderate fat meal, High fat meal, High fat liquid meal
Other
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Davis, California
Conditions
Anorexia in Adolescence, Anorexia Nervosa, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type, Anorexia Nervosa Restricting Type, Anorexia Nervosa With Significantly Low Body Weight, Body Composition Changes, Growth & Development, Malnutrition Severe, Malnutrition, Calorie
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
15 Years to 26 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2031
U.S. locations
2
States / cities
San Francisco, California • Denver, Colorado