- Conditions
- Restless Legs Syndrome
- Interventions
- Apomorphine Sublingual Film, Placebo
- Drug
- Lead sponsor
- William Ondo, MD
- Other
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 16 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Houston, Texas
Search Results
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 109
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Restless Legs Syndrome
- Interventions
- NTX100 Neuromodulation System
- Device
- Lead sponsor
- Noctrix Health, Inc.
- Industry
- Eligibility
- 22 Years to 80 Years
- Enrollment
- 103 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 7
- States / cities
- San Leandro, California • Colorado Springs, Colorado • Atlanta, Georgia + 4 more
- Conditions
- Restless Legs Syndrome
- Interventions
- Chylobinoid Topical Cream
- Drug
- Lead sponsor
- Synthonics Inc
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Sarasota, Florida
- Conditions
- Sleep Disorder, Restless Legs Syndrome
- Interventions
- Istradefylline (KW-6002)
- Drug
- Lead sponsor
- Kyowa Kirin, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 160 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2006
- U.S. locations
- 1
- States / cities
- Princeton, New Jersey
- Conditions
- Restless Legs Syndrome
- Interventions
- Ropinirole Extended Release (XR)
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 450 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 59
- States / cities
- Alabaster, Alabama • Jasper, Alabama • Mesa, Arizona + 54 more
- Conditions
- Restless Legs Syndrome
- Interventions
- Noninvasive Peripheral Nerve Stimulation (NPNS)
- Device
- Lead sponsor
- Noctrix Health, Inc.
- Industry
- Eligibility
- 18 Years to 89 Years
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 2
- States / cities
- Downey, California • Dublin, Ohio
- Conditions
- Restless Legs Syndrome
- Interventions
- NTX100
- Device
- Lead sponsor
- Noctrix Health, Inc.
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 325 participants
- Timeline
- 2023 – 2027
- U.S. locations
- 7
- States / cities
- Downey, California • San Ramon, California • Newton, Massachusetts + 4 more
- Conditions
- Restless Legs Syndrome
- Interventions
- Rotigotine
- Drug
- Lead sponsor
- UCB Pharma
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 279 participants
- Timeline
- 2005 – 2007
- U.S. locations
- 1
- States / cities
- RTP, North Carolina
- Conditions
- Restless Legs Syndrome
- Interventions
- Levetiracetam (Keppra)
- Drug
- Lead sponsor
- Sleep Health Centers
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2005
- U.S. locations
- 1
- States / cities
- Newton, Massachusetts
- Conditions
- Restless Legs Syndrome
- Interventions
- Noctrix Health NPNS device v1.0 - Active, Noctrix Health NPNS device v1.0 - Sham
- Device
- Lead sponsor
- Noctrix Health, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 43 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 3
- States / cities
- Downey, California • Menlo Park, California • San Ramon, California
- Conditions
- Sleep Disorders, Sleep Apnea, Obstructive, Restless Legs Syndrome, Sleep Disorders, Circadian Rhythm, Sleep Initiation and Maintenance Disorders
- Interventions
- Sleep Hygiene Education, Expert-Led Sleep Disorders Screening and Treatment, Online Sleep Disorders Screening
- Behavioral · Other
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 683 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2005 – 2010
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Restless Legs Syndrome
- Interventions
- Rotigotine
- Drug
- Lead sponsor
- UCB BIOSCIENCES, Inc.
- Industry
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 12
- States / cities
- Little Rock, Arkansas • Los Angeles, California • Orange, California + 9 more
- Conditions
- Restless Leg Disorder, Restless Leg Syndrome (RLS), Pregnancy, Sleep Disorder (Disorder)
- Interventions
- Peroneal Nerve Stimulation (PNS) Device
- Device
- Lead sponsor
- Rhode Island Hospital
- Other
- Eligibility
- 18 Years and older · Female only
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Providence, Rhode Island
- Conditions
- Restless Legs Syndrome
- Interventions
- Aplindore, Placebo
- Drug
- Lead sponsor
- Ligand Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2008
- U.S. locations
- 5
- States / cities
- Hallandale, Florida • Atlanta, Georgia • Crestview Hills, Kentucky + 2 more
- Conditions
- Multiple Sclerosis, Restless Legs Syndrome
- Interventions
- Behavioral Intervention (BIPAMS)
- Behavioral
- Lead sponsor
- University of Alabama at Birmingham
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Restless Legs Syndrome
- Interventions
- GSK1838262 600 mg, GSK1838262 450 mg, GSK1838262 300 mg, GSK1838262 Placebo match
- Drug
- Lead sponsor
- XenoPort, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 501 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 42
- States / cities
- Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 37 more
- Conditions
- Restless Legs Syndrome
- Interventions
- Not listed
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 68 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Alzheimer Disease
- Interventions
- Gabapentin Enacarbil, Placebo Oral Tablet
- Drug
- Lead sponsor
- University of Texas at Austin
- Other
- Eligibility
- 55 Years and older
- Enrollment
- 156 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2023
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Restless Legs Syndrome, Restless Legs Syndrome (RLS)
- Interventions
- GSK1838262 Extended Release Tablets, Placebo
- Drug
- Lead sponsor
- XenoPort, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 136 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 24
- States / cities
- Jasper, Alabama • San Diego, California • Hallandale, Florida + 20 more
- Conditions
- Restless Leg Syndrome
- Interventions
- incobotulinumtoxinA, Placebo
- Drug
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Sleep Disorder, Restless Legs Syndrome, Opioid-use Disorder, Opioid Withdrawal
- Interventions
- Pramipexole, Placebo
- Drug
- Lead sponsor
- Massachusetts General Hospital
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 2
- States / cities
- Boston, Massachusetts • Quincy, Massachusetts
- Conditions
- Restless Legs Syndrome
- Interventions
- Ropinirole Extended Release (XR)
- Drug
- Lead sponsor
- GlaxoSmithKline
- Industry
- Eligibility
- 18 Years to 79 Years
- Enrollment
- 380 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2006
- U.S. locations
- 60
- States / cities
- Alabaster, Alabama • Jasper, Alabama • Mesa, Arizona + 55 more
- Conditions
- Restless Legs Syndrome
- Interventions
- Horizant
- Drug
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2019
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- RLS
- Interventions
- HORIZANT 300 mg, HORIZANT 600 mg, Placebo
- Drug
- Lead sponsor
- XenoPort, Inc.
- Industry
- Eligibility
- 13 Years to 17 Years
- Enrollment
- 132 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2023
- U.S. locations
- 12
- States / cities
- Redwood City, California • Gulf Breeze, Florida • Winter Park, Florida + 9 more