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ClinicalTrials.gov public records Last synced Oct 27, 2026, 3:42 AM EDT

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Showing 1–24 of 100 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Rotator Cuff Disease Clear all
Active, not recruiting Not applicable Interventional

Rotator Cuff Sparing Total Arthroplasty

NCT01961986
View directory record Official record
Conditions
Osteoarthritis, Inflammatory Arthritis
Interventions
TSR - traditional subscapularis release, TSR - rotator cuff sparing
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 27, 2026, 3:42 AM EDT
Recruiting Not applicable Interventional

Autologous Fat Grafting for the Treatment of Chronic Tendinopathy

NCT07748793
View directory record Official record
Conditions
Chronic Tendinopathy
Interventions
Adipose Stem/Stromal Cells for Enthesis/Tendon Therapy (ASSET) Injection
Procedure
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 27, 2026, 3:42 AM EDT
Terminated No phase listed Observational

MDR SureLock All-Suture Anchor

NCT04093700
View directory record Official record
Conditions
Shoulder Pain, Shoulder Injuries, Shoulder Disease, Shoulder Pain Chronic, Shoulder Syndrome, Labral Tear, Glenoid
Interventions
SureLock All-Suture Anchor
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
14 Years to 45 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lutherville, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 27, 2026, 3:42 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Clinical Outcomes Related to Arthroscopic Rotator Cuff Repair Recovery Using Incrediwear

NCT06669741
View directory record Official record
Conditions
Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Arthropathy of Left Shoulder (Disorder), Rotator Cuff Arthropathy of Right Shoulder (Disorder), Rotator Cuff Arthropathy of Bilateral Shoulders
Interventions
Placebo, Shoulder Sleeve
Device
Lead sponsor
Texas Bone and Joint
Other
Eligibility
18 Years to 75 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Denton, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2025 · Synced Oct 27, 2026, 3:42 AM EDT
Completed Phase 4 Interventional Results available

Opioid-Free Shoulder Arthroplasty

NCT03540030
View directory record Official record
Conditions
Opioid Use, Shoulder Osteoarthritis, Avascular Necrosis, Rotator Cuff Tear, Arthritis;Inflammatory
Interventions
Gabapentin, Celecoxib, toradol, acetaminophen, regional block, propofol, IV lidocaine, rocuronium, vecuronium, sevoflurane, desflurane
Drug
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
50 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 14, 2020 · Synced Oct 27, 2026, 3:42 AM EDT
Recruiting No phase listed Observational

Exactech Shoulder Post Market Clinical Follow-up Study

NCT05603728
View directory record Official record
Conditions
Osteo Arthritis Shoulders, Osteonecrosis, Rotator Cuff Tears, Rotator Cuff Tear Arthropathy, Ankylosing Spondylitis, Post-traumatic Osteoarthritis, Rheumatoid Arthritis, Fracture, Infections
Interventions
Not listed
Lead sponsor
Exactech
Industry
Eligibility
21 Years and older
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2031
U.S. locations
24
States / cities
Laguna Woods, California • Redwood City, California • Stockton, California + 20 more
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 27, 2026, 3:42 AM EDT
Withdrawn Not applicable Interventional

Connective Tissue Matrix Compared to Steroid Injections for Rotator Cuff Tendinopathy

NCT06712290
View directory record Official record
Conditions
Rotator Cuff Tendinopathy
Interventions
celgene, Corticosteroid
Drug
Lead sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 27, 2026, 3:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Results of Rotator Cuff Repair

NCT01549912
View directory record Official record
Conditions
Shoulder Dislocation
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
35 Years and older
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 6, 2015 · Synced Oct 27, 2026, 3:42 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Natural History of Shoulder Pathology in Manual Wheelchair Users

NCT02600910
View directory record Official record
Conditions
Paraplegia, Spinal Cord Injuries, Shoulder Pain, Tendinopathy
Interventions
Not listed
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
2
States / cities
Rochester, Minnesota • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 27, 2026, 3:42 AM EDT
Active, not recruiting Phase 2 Interventional

Stromal Vascular Fraction Cell Therapy to Improve the Repair of Rotator Cuff Tears

NCT03332238
View directory record Official record
Conditions
Rotator Cuff Tear, Muscle Atrophy, Tendon Tear
Interventions
Autologous Stomal Vascular Fraction Material, Ringer's solution
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
45 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 27, 2026, 3:42 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Vitamin D3 Supplementation for Vitamin D Deficiency in Rotator Cuff Repair Surgery

NCT05009498
View directory record Official record
Conditions
Vitamin D Deficiency, Rotator Cuff Tears
Interventions
Vitamin D3 supplementation, Placebo
Dietary Supplement · Other
Lead sponsor
Community Memorial Health System
Other
Eligibility
18 Years to 65 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Oct 27, 2026, 3:42 AM EDT
Completed Not applicable Interventional

Early Range of Motion Following Arthroscopic Rotator Cuff Repair

NCT00845715
View directory record Official record
Conditions
Rotator Cuff Disease
Interventions
Early motion, Standard motion
Other
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 70 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 25, 2017 · Synced Oct 27, 2026, 3:42 AM EDT
Completed No phase listed Observational Results available

PMCF Study on the Safety, Performance and Clinical Benefits Data of the ToggleLoc™ 2.9mm and JuggerLoc™ in the Shoulder

NCT05584553
View directory record Official record
Conditions
Bankart Lesions, SLAP Lesion, Acromioclavicular; Dislocation, Capsular Shift/Capsulolabral Reconstruction, Deltoid Repair, Rotator Cuff Tear Repair, Biceps Tendon Disorder
Interventions
ToggleLoc 2.9 mm soft tissue device, JuggerLoc soft tissue device
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
City of Saint Peters, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 28, 2025 · Synced Oct 27, 2026, 3:42 AM EDT
Completed Not applicable Interventional Results available

Rotator Cuff Pathway

NCT03717753
View directory record Official record
Conditions
Shoulder Pain
Interventions
Pathway
Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Oct 27, 2026, 3:42 AM EDT
Recruiting Phase 4 Interventional

Bioinductive Patch for Full-Thickness Rotator Cuff Tears

NCT05439850
View directory record Official record
Conditions
Rotator Cuff Tears, Rotator Cuff Tear Arthropathy
Interventions
arthroscopic rotator cuff repair, Bioinductive implant, Ultrasound Imaging
Procedure · Biological · Diagnostic Test
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 27, 2026, 3:42 AM EDT
Recruiting No phase listed Observational

FX Shoulder Prospective Clinical Study

NCT06078865
View directory record Official record
Conditions
Osteoarthritis Shoulder, Rotator Cuff Syndrome of Shoulder and Allied Disorders, Fracture, Shoulder
Interventions
FX Artificial Shoulder Prosthesis
Device
Lead sponsor
FX Shoulder Solutions
Industry
Eligibility
Not listed
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2031
U.S. locations
4
States / cities
Gilbert, Arizona • Marietta, Ohio • Wakefield, Rhode Island + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 27, 2026, 3:42 AM EDT
Completed Not applicable Interventional

Type of Exercise and Education in Patients With SubAcromial Pain Syndrome

NCT03127839
View directory record Official record
Conditions
Shoulder Pain
Interventions
Eccentric Strengthening, Traditional Strengthening, Pain education
Procedure · Behavioral
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 27, 2026, 3:42 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Blood Flow Restriction Following Hip Arthroscopy

NCT04113759
View directory record Official record
Conditions
Labral Tear, Glenoid, Femoral Acetabular Impingement
Interventions
Blood Flow Restriction Rehabilitative Therapy, Sham BFR Rehabilitative Therapy
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 27, 2026, 3:42 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Liposomal Bupivacaine Plus Bupivacaine Peripheral Nerve Blockade Versus Ropivacaine Plus Dexamethasone Peripheral Nerve Blockade for Arthroscopic Rotator Cuff Repair

NCT04737980
View directory record Official record
Conditions
Rotator Cuff Tears, Shoulder Pain
Interventions
Liposomal bupivacaine, Bupivacaine Hcl 0.5% Inj, Ropivacaine 0.5% Injectable Solution, Dexamethasone
Drug
Lead sponsor
Hospital for Special Surgery Florida
Other
Eligibility
18 Years and older
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
West Palm Beach, Florida
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Oct 27, 2026, 3:42 AM EDT
Completed Not applicable Interventional

The Influence of a Cognitive Behavioral Approach on Changing Patient Expectations in Shoulder Pain

NCT03353272
View directory record Official record
Conditions
Rotator Cuff Impingement Syndrome, Rotator Cuff Injury, Shoulder Pain
Interventions
Patient Engagement Education and Restructuring of Cognitions
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Oct 27, 2026, 3:42 AM EDT
Terminated Not applicable Interventional

Onlay Versus Inlay Humeral Component in Reverse Total Shoulder Arthroplasty

NCT05297305
View directory record Official record
Conditions
Arthritis Shoulder, Rotator Cuff Injuries
Interventions
Tornier Ascend Flex stem, Tornier Perform Stem Reverse+
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 27, 2026, 3:42 AM EDT
Recruiting Not applicable Interventional

Embolization Treatment of Chronic Refractory Shoulder Tendinopathy

NCT06095050
View directory record Official record
Conditions
Shoulder Pain, Tendinopathy, Rotator Cuff Tendinitis, Rotator Cuff Tendinosis, Embolization, Arterial Occlusion
Interventions
Embolization, Physical Therapy
Device · Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 27, 2026, 3:42 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Abduction Brace Versus Antirotation Sling for Immobilization Following Reverse Shoulder Arthroplasty and Rotator Cuff Repair

NCT03488433
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
Interventions
Abduction brace, Antirotation sling
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 19, 2019 · Synced Oct 27, 2026, 3:42 AM EDT
Completed Not applicable Interventional Results available

Treatment of the Rotator Cuff Disease With Platelet Rich Plasma Injection

NCT01123889
View directory record Official record
Conditions
Subacromial Impingement Syndrome, Partial Thickness Rotator Cuff Tear
Interventions
platelet rich plasma injection, corticosteroid injection
Biological · Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 89 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2014 · Synced Oct 27, 2026, 3:42 AM EDT