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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Rotator Cuff Disease Clear all
Recruiting No phase listed Observational

Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block

NCT04209504
View directory record Official record
Conditions
Shoulder Surgery, Shoulder Pain, Shoulder Injuries, Shoulder Arthritis, Shoulder Disease, Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Arthropathy of Left Shoulder, Rotator Cuff Arthropathy of Right Shoulder, Rotator Cuff Repair
Interventions
Ultrasound, Ropivacaine, Bupivacaine, MediPines AGM100 Advanced Respiratory Monitoring System
Diagnostic Test · Drug · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Jul 22, 2026, 5:57 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Natural History of Shoulder Pathology in Manual Wheelchair Users

NCT02600910
View directory record Official record
Conditions
Paraplegia, Spinal Cord Injuries, Shoulder Pain, Tendinopathy
Interventions
Not listed
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 70 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
2
States / cities
Rochester, Minnesota • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Jul 22, 2026, 5:57 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Reverse Total Shoulder Arthroplasty: A Data Analysis on Patients Undergoing Reverse Total Shoulder Arthroplasty

NCT03617107
View directory record Official record
Conditions
Osteo Arthritis Shoulders, Proximal Humeral Fracture, Rotator Cuff Tear, Rotator Cuff Tear Arthropathy
Interventions
reverse total shoulder arthroplasty
Other
Lead sponsor
The Orthopaedic Research & Innovation Foundation
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Edgewood, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 24, 2019 · Synced Jul 22, 2026, 5:57 AM EDT
Withdrawn Not applicable Interventional

Effect of Postop Rehab Methods on Outcomes Following Reverse Shoulder Arthroplasty

NCT04285606
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy, Shoulder Osteoarthritis
Interventions
Patient-led rehab with short immobilization
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 20, 2022 · Synced Jul 22, 2026, 5:57 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Rotator Cuff Repair Using Standard Double Row Technique With Platelet Rich Fibrin Membrane vs. Standard Double Row Technique

NCT02256891
View directory record Official record
Conditions
Rotator Cuff Tear
Interventions
PRFM, Double Row
Device · Procedure
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 8, 2017 · Synced Jul 22, 2026, 5:57 AM EDT
Active, not recruiting Not applicable Interventional

Rotator Cuff Sparing Total Arthroplasty

NCT01961986
View directory record Official record
Conditions
Osteoarthritis, Inflammatory Arthritis
Interventions
TSR - traditional subscapularis release, TSR - rotator cuff sparing
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 5, 2026 · Synced Jul 22, 2026, 5:57 AM EDT
Completed Not applicable Interventional

Accuracy of Needle Placement Into The Subacromial Space of The Shoulder

NCT01330641
View directory record Official record
Conditions
Rotator Cuff Tendonitis
Interventions
Injection of Subacromial Bursa
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2011 · Synced Jul 22, 2026, 5:57 AM EDT
Completed No phase listed Observational Results available

PMCF Study on the Safety, Performance and Clinical Benefits Data of the ToggleLoc™ 2.9mm and JuggerLoc™ in the Shoulder

NCT05584553
View directory record Official record
Conditions
Bankart Lesions, SLAP Lesion, Acromioclavicular; Dislocation, Capsular Shift/Capsulolabral Reconstruction, Deltoid Repair, Rotator Cuff Tear Repair, Biceps Tendon Disorder
Interventions
ToggleLoc 2.9 mm soft tissue device, JuggerLoc soft tissue device
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
City of Saint Peters, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Jul 22, 2026, 5:57 AM EDT
Completed Not applicable Interventional Results available

Rotator Cuff Pathway

NCT03717753
View directory record Official record
Conditions
Shoulder Pain
Interventions
Pathway
Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Jul 22, 2026, 5:57 AM EDT
Completed Not applicable Interventional Results available

Treatment of the Rotator Cuff Disease With Platelet Rich Plasma Injection

NCT01123889
View directory record Official record
Conditions
Subacromial Impingement Syndrome, Partial Thickness Rotator Cuff Tear
Interventions
platelet rich plasma injection, corticosteroid injection
Biological · Drug
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 89 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Feb 10, 2014 · Synced Jul 22, 2026, 5:57 AM EDT
Recruiting Not applicable Interventional

BFRT for Subacromial Pain

NCT06873113
View directory record Official record
Conditions
Shoulder Pain
Interventions
Active BFRT, Sham BFRT, Strengthening Exercises with BFRT, Skilled Physical Therapy Care
Device · Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 50 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 7, 2025 · Synced Jul 22, 2026, 5:57 AM EDT
Not listed Not applicable Interventional

SMR Stemless Reverse Vs SMR Reverse Shoulder System

NCT04697004
View directory record Official record
Conditions
Arthroplasty, Replacement
Interventions
Investigational Arm: SMR Stemless Reverse, Control Arm: SMR Reverse Shoulder System
Device
Lead sponsor
Limacorporate S.p.a
Industry
Eligibility
22 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
11
States / cities
Los Angeles, California • Denver, Colorado • Boca Raton, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Jul 22, 2026, 5:57 AM EDT
Completed Not applicable Interventional Results available

Physical Therapy Versus Steroid Injection for Shoulder Impingement Syndrome

NCT01190891
View directory record Official record
Conditions
Shoulder Impingement Syndrome
Interventions
Manual Physical Therapy, Corticosteroid Injection
Procedure
Lead sponsor
Madigan Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Apr 28, 2016 · Synced Jul 22, 2026, 5:57 AM EDT
Active, not recruiting No phase listed Observational

Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder System

NCT01480440
View directory record Official record
Conditions
Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture, Irreducible 3-and 4-part Proximal Humeral Fractures, Avascular Necrosis, Gross Rotator Cuff Deficiency, Revision Total Shoulder Arthroplasty
Interventions
Trabecular Metal Reverse Shoulder System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2026
U.S. locations
4
States / cities
San Francisco, California • Louisville, Kentucky • Egg Harbor, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Jul 22, 2026, 5:57 AM EDT
Completed Not applicable Interventional Results available

Feasibility of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery

NCT06818708
View directory record Official record
Conditions
Rotator Cuff Injuries, Shoulder Disease, Hallux Valgus, Ankle Arthropathy
Interventions
Experimental Treatment
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Nov 17, 2025 · Synced Jul 22, 2026, 5:57 AM EDT
Completed Not applicable Interventional

Dry Needling for Sub Acromial Pain Syndrome

NCT03442894
View directory record Official record
Conditions
Subacromial Impingement Syndrome
Interventions
Standard Physical Therapy Treatment, Dry Needling, Sham Dry Needling
Procedure
Lead sponsor
59th Medical Wing
Federal
Eligibility
18 Years to 65 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Jul 22, 2026, 5:57 AM EDT
Enrolling by invitation Phase 1 Interventional

E-CEL UVEC Cells as an Adjunct Cell Therapy for the Arthroscopic Rotator Cuff Repair in Adults

NCT04057833
View directory record Official record
Conditions
Rotator Cuff Tears, Muscle Atrophy or Weakness, Tendon Rupture - Shoulder, Safety Issues
Interventions
E-CEL UVEC
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
45 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jul 22, 2026, 5:57 AM EDT
Withdrawn Phase 4 Interventional

Analysis for NSAID VS Corticosteroid Shoulder Injection in Diabetic Patients

NCT03319784
View directory record Official record
Conditions
Rotator Cuff Tear, Rotator Cuff Injury, Rotator Cuff Tendinitis, Diabetes Mellitus
Interventions
Ketorolac, Triamcinolone Acetonide
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 14, 2019 · Synced Jul 22, 2026, 5:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Can Blood Flow Restriction Therapy Improve Strength and Cross-Sectional Area for Shoulder External Rotators Better Than Exercise Alone?

NCT04596020
View directory record Official record
Conditions
Can Blood Flow Restriction Therapy Augments Strength Gains in the Rotator Cuff, Muscle Weakness
Interventions
Blood Flow Restriction Group (exercise with blood flow restriction using a Delfi unit)
Other
Lead sponsor
George Fox University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Newberg, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 21, 2020 · Synced Jul 22, 2026, 5:57 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Abduction Brace Versus Antirotation Sling for Immobilization Following Reverse Shoulder Arthroplasty and Rotator Cuff Repair

NCT03488433
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
Interventions
Abduction brace, Antirotation sling
Device
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Jul 22, 2026, 5:57 AM EDT
Active, not recruiting Not applicable Interventional

Patient Outcomes Collection: How Can we do Better?

NCT03653455
View directory record Official record
Conditions
Shoulder Pain
Interventions
Email reminders, Pre- and Post-operative discussion, Incentive
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jul 22, 2026, 5:57 AM EDT
Terminated No phase listed Observational

MDR SureLock All-Suture Anchor

NCT04093700
View directory record Official record
Conditions
Shoulder Pain, Shoulder Injuries, Shoulder Disease, Shoulder Pain Chronic, Shoulder Syndrome, Labral Tear, Glenoid
Interventions
SureLock All-Suture Anchor
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
14 Years to 45 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lutherville, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Jul 22, 2026, 5:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Hip Arthroscopy Postoperative Opioid Demands

NCT04094701
View directory record Official record
Conditions
Opioid Use, Pain, Femoral Acetabular Impingement, Labral Tear, Glenoid
Interventions
Control Group Regimen, Opioid reduced regimen
Other
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Jul 22, 2026, 5:57 AM EDT
Recruiting No phase listed Observational

Exactech Shoulder Post Market Clinical Follow-up Study

NCT05603728
View directory record Official record
Conditions
Osteo Arthritis Shoulders, Osteonecrosis, Rotator Cuff Tears, Rotator Cuff Tear Arthropathy, Ankylosing Spondylitis, Post-traumatic Osteoarthritis, Rheumatoid Arthritis, Fracture, Infections
Interventions
Not listed
Lead sponsor
Exactech
Industry
Eligibility
21 Years and older
Enrollment
20,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2031
U.S. locations
24
States / cities
Laguna Woods, California • Redwood City, California • Stockton, California + 19 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jul 22, 2026, 5:57 AM EDT