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ClinicalTrials.gov public records Last synced Oct 21, 2026, 1:23 AM EDT

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Showing 1–24 of 59 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Safety Issues Clear all
Withdrawn Phase 2 Interventional

Open-Label Depakote ER in Patients With Bipolar I or II Depression and Alcohol Abuse or Dependence

NCT00204503
View directory record Official record
Conditions
Bipolar I or II Depression and Alcohol Abuse or Dependence
Interventions
Depakote ER
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 31, 2015 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Phase 1 Study of EXT608 in Healthy Adults

NCT05408663
View directory record Official record
Conditions
Safety Issues
Interventions
EXT608, Placebo
Drug · Other
Lead sponsor
Extend Biosciences Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lenexa, Kansas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2025 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A First-in-Human Study of BNZ132-1-40

NCT03046459
View directory record Official record
Conditions
Healthy
Interventions
BNZ132-1-40
Biological
Lead sponsor
Bioniz Therapeutics
Industry
Eligibility
18 Years to 50 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 22, 2017 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Oral Mucosal Effects In Adult Smokers Associated With Two Nicotine Lozenge Formulations

NCT03087786
View directory record Official record
Conditions
Safety Issues
Interventions
Nicotine Bitartrate Lozenge 4mg, Nicotine Polacrilex 4Mg Lozenge
Drug
Lead sponsor
Niconovum USA
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Not applicable Interventional Results available

Aerosolization During Upper Endoscopy

NCT06006078
View directory record Official record
Conditions
Infectious, Gastro-Intestinal Disorder, Safety Issues
Interventions
Endoscopic Patient Facemask
Device
Lead sponsor
Anthony Lembo
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Oct 21, 2026, 1:23 AM EDT
Completed No phase listed Observational

Neoadjuvant Chemotherapy or Chemoradiotherapy in Resectable Oesophageal Carcinoma（NewEC Study）

NCT04027543
View directory record Official record
Conditions
Radiotherapy Side Effect, Chemotherapy Effect, Oesophageal Carcinoma, Effect of Drugs, Safety Issues
Interventions
Neoadjuvant chemoradiotherapy, Oesophagectomy, Neoadjuvant chemotherapy
Combination Product · Procedure · Drug
Lead sponsor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Other
Eligibility
18 Years to 80 Years
Enrollment
423 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 29, 2020 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-Invasive Blood Test Cross-Validation Study

NCT03991637
View directory record Official record
Conditions
Reproducibility of Results, Safety Issues
Interventions
Non-Invasive Comprehensive Metabolic Panel
Device
Lead sponsor
Joseph Allen Jr.
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Jun 24, 2019 · Synced Oct 21, 2026, 1:23 AM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

A Phase1 Study of VIB9600

NCT03621605
View directory record Official record
Conditions
Safety Issues
Interventions
VIB9600, Placebos
Biological · Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 13, 2024 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Tolerability of Soy Fiber

NCT04499482
View directory record Official record
Conditions
Safety Issues, Tolerance
Interventions
Food
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
70 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Group-based Intervention for Club Patrons

NCT03652688
View directory record Official record
Conditions
Drink Too Much, Drinking, Binge, Drunk, Drug Use, Aggression, Aggression Sexual, Peer Group, Safety Issues, Harm Reduction
Interventions
Nightlife Safety Plans (NSP), Fire Safety
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
21 Years and older
Enrollment
959 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2025 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Phase I Study of PH100 (Ecklonia Cava Phlorotannins)

NCT04335045
View directory record Official record
Conditions
Safety Issues
Interventions
Placebo, PH100 100mg, PH100 200mg, PH100 400mg, PH100 800mg, PH100 1200mg, PH100 1600mg
Drug
Lead sponsor
Phloronol Inc.
Industry
Eligibility
40 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Oct 21, 2026, 1:23 AM EDT
Enrolling by invitation Not applicable Interventional

Pediatric Trauma Centers RE-AIM at Gun Safety

NCT06123611
View directory record Official record
Conditions
Firearm Injury, Safety Issues
Interventions
Adopting Comprehensive Training for FireArm Safety in Trauma centers
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
11 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 21, 2026, 1:23 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Same Day Discharge vs. Overnight Stay After Hysterectomy

NCT03627234
View directory record Official record
Conditions
Satisfaction, Safety Issues, Quality of Life
Interventions
Same Day Discharge, Overnight Stay
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 65 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 13, 2022 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Not applicable Interventional

Meds@HOME App to Support Medication Safety

NCT05816590
View directory record Official record
Conditions
Medication Errors and Other Product Use Errors and Issues
Interventions
Med@HOME Mobile App
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Not listed
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 25, 2025 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Not applicable Interventional

Effect of Naringenin and Beta Carotene on Energy Expenditure

NCT04697355
View directory record Official record
Conditions
Energy Expenditure, Safety Issues, Glucose Metabolism
Interventions
naringenin and beta carotene
Dietary Supplement
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 9, 2021 · Synced Oct 21, 2026, 1:23 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Adult Trauma Centers RE-AIM at Gun Safety

NCT06302452
View directory record Official record
Conditions
Firearm Injury, Safety Issues
Interventions
Adopting Comprehensive Training for FireArm Safety in Trauma Centers
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
1,776 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
3
States / cities
Baltimore, Maryland • York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing the Effects of a Cannabidiol Derived From Hemp Supplement in Healthy Adults

NCT05212402
View directory record Official record
Conditions
Healthy, Safety Issues
Interventions
Cannabinol, Placebo
Dietary Supplement · Other
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 55 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Oct 21, 2026, 1:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Safety-Enhancing Motor Vehicle Child Safety Seat

NCT06384989
View directory record Official record
Conditions
Motor Vehicle Injury, Safety Issues
Interventions
Child restraint system with load leg feature
Other
Lead sponsor
Minnesota HealthSolutions
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Interactive Web Platform to Teach Children Hunting, Shooting and Firearms Safety

NCT04622943
View directory record Official record
Conditions
Safety Issues, Injuries, Firearm Injury
Interventions
firearms safety, nutrition
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
10 Years to 12 Years
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 21, 2026, 1:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Survey of Housestaff Attitudes Toward Patient Care and Safety

NCT00845052
View directory record Official record
Conditions
Safety Issues, Patient Care
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
20 Years to 50 Years
Enrollment
674 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2017 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Phase 1Phase 2 Interventional

Phase1/2a Study for IPG7236 in Patients With Advanced Solid Tumors

NCT05142592
View directory record Official record
Conditions
Safety Issues, Tolerability, Pharmacokinetics
Interventions
IPG7236
Drug
Lead sponsor
Nanjing Immunophage Biotech Co., Ltd
Industry
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Portland, Oregon • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Not applicable Interventional Results available

Care Coordination/Home Telehealth to Safeguard Care in CKD

NCT03038126
View directory record Official record
Conditions
Safety Issues, Chronic Kidney Disease
Interventions
CCHT, Usual care
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
60 Years and older
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Oct 21, 2026, 1:23 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Active Workplace Study

NCT03556670
View directory record Official record
Conditions
Sedentary Lifestyle, Occupational Exposure, Health Behavior, Safety Issues
Interventions
Total Worker Health, Control
Behavioral · Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
264 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 19, 2020 · Synced Oct 21, 2026, 1:23 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pupillary Unrest in Ambient Light, and Relationship to Opioid-Induced Respiratory Depression

NCT04301895
View directory record Official record
Conditions
Opioid; Intoxication, Perception Disturbance (Acute), Acute Pain, Overdose of Opiate, Respiratory Depression, Safety Issues
Interventions
Continuous conversational interaction, Remifentanil infusion
Behavioral · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
20 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2020 · Synced Oct 21, 2026, 1:23 AM EDT