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ClinicalTrials.gov public records Last synced Jul 21, 2026, 11:21 AM EDT

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Showing 1–24 of 59 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Safety Issues Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Rectal Insert TAF/EVG Pre-Exposure Prophylaxis (RITE PrEP) Study

NCT06274398
View directory record Official record
Conditions
Safety Issues
Interventions
TAF/EVG rectal insert, Matching placebo rectal insert
Drug
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 59 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Jul 21, 2026, 11:21 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Phase 1A Safety Trial of Inhaled PK10571 (GB002)

NCT03473236
View directory record Official record
Conditions
Safety Issues
Interventions
GB002, Generic Dry Powder Inhaler, Placebo
Drug · Device
Lead sponsor
GB002, Inc., a wholly owned subsidiary of Gossamer Bio, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Jul 21, 2026, 11:21 AM EDT
Completed Phase 1 Interventional

Safety and Tolerability Trial (MVA-BN-Brachyury/FPV-Brachyury)

NCT03349983
View directory record Official record
Conditions
Safety Issues
Interventions
MVA-BN-Brachyury/ FPV-Brachyury
Biological
Lead sponsor
Bavarian Nordic
Industry
Eligibility
18 Years to 85 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 25, 2020 · Synced Jul 21, 2026, 11:21 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Different Ingestion Doses of Celastrol on Human Sperm Motility

NCT05413226
View directory record Official record
Conditions
Safety Issues
Interventions
Celastrol
Dietary Supplement
Lead sponsor
Legend Labz, Inc.
Industry
Eligibility
18 Years to 40 Years · Male only
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Jul 21, 2026, 11:21 AM EDT
Completed No phase listed Observational

Neoadjuvant Chemotherapy or Chemoradiotherapy in Resectable Oesophageal Carcinoma（NewEC Study）

NCT04027543
View directory record Official record
Conditions
Radiotherapy Side Effect, Chemotherapy Effect, Oesophageal Carcinoma, Effect of Drugs, Safety Issues
Interventions
Neoadjuvant chemoradiotherapy, Oesophagectomy, Neoadjuvant chemotherapy
Combination Product · Procedure · Drug
Lead sponsor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Other
Eligibility
18 Years to 80 Years
Enrollment
423 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 28, 2020 · Synced Jul 21, 2026, 11:21 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Phase1 First in Human Ascending Dose Study to Evaluate the Safety and Tolerability of FC-12738 in Health Adults

NCT05978908
View directory record Official record
Conditions
Safety Issues, Tolerance
Interventions
FC-12738, Saline
Drug
Lead sponsor
Neurodegenerative Disease Research Inc
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Berlin, New Jersey
Source: ClinicalTrials.gov public record
Updated May 24, 2025 · Synced Jul 21, 2026, 11:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Group-based Intervention for Club Patrons

NCT03652688
View directory record Official record
Conditions
Drink Too Much, Drinking, Binge, Drunk, Drug Use, Aggression, Aggression Sexual, Peer Group, Safety Issues, Harm Reduction
Interventions
Nightlife Safety Plans (NSP), Fire Safety
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
21 Years and older
Enrollment
959 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Jul 21, 2026, 11:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-Invasive Blood Test Cross-Validation Study

NCT03991637
View directory record Official record
Conditions
Reproducibility of Results, Safety Issues
Interventions
Non-Invasive Comprehensive Metabolic Panel
Device
Lead sponsor
Joseph Allen Jr.
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Jun 23, 2019 · Synced Jul 21, 2026, 11:21 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Adult Trauma Centers RE-AIM at Gun Safety

NCT06302452
View directory record Official record
Conditions
Firearm Injury, Safety Issues
Interventions
Adopting Comprehensive Training for FireArm Safety in Trauma Centers
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
1,776 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
3
States / cities
Baltimore, Maryland • York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Jul 21, 2026, 11:21 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Role of a CCK Receptor Antagonist Proglumide in Management of Chronic Pancreatitis

NCT05551858
View directory record Official record
Conditions
Safety Issues, Pain, Pancreas Fibrosis
Interventions
Proglumide, Placebo
Drug
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 75 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Jul 21, 2026, 11:21 AM EDT
Not listed Phase 1 Interventional

Phase 1 Study of Oral RH324 in Advanced Non-Small Cell Lung Cancer

NCT05580172
View directory record Official record
Conditions
Safety Issues
Interventions
RH324
Drug
Lead sponsor
ReHeva Biosciences,Inc.
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 16, 2022 · Synced Jul 21, 2026, 11:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Buck Institute Ketone Ester RCT

NCT05585762
View directory record Official record
Conditions
Tolerance, Safety Issues, Aging
Interventions
Ketone ester, Non-ketone placebo
Other
Lead sponsor
Buck Institute for Research on Aging
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Novato, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2024 · Synced Jul 21, 2026, 11:21 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

MIST3: Active Patient Safety Reporting

NCT04161677
View directory record Official record
Conditions
Safety Issues
Interventions
Not listed
Lead sponsor
Parker University
Other
Eligibility
18 Years to 65 Years
Enrollment
161 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Jul 21, 2026, 11:21 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Survey of Housestaff Attitudes Toward Patient Care and Safety

NCT00845052
View directory record Official record
Conditions
Safety Issues, Patient Care
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
20 Years to 50 Years
Enrollment
674 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Jul 21, 2026, 11:21 AM EDT
Completed Phase 1 Interventional

A Phase 1 Study of the Safety and Tolerability of ICM20 in Adults

NCT05523596
View directory record Official record
Conditions
Safety Issues
Interventions
ICM20, Benznidazole
Drug
Lead sponsor
IC-MedTech Corporation
Industry
Eligibility
18 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
3
States / cities
Glen Burnie, Maryland • Houston, Texas • Falls Church, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 21, 2026, 11:21 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Corrections Work's Adverse Effects and a Total Worker Health Program to Enhance Well-being

NCT05608889
View directory record Official record
Conditions
Occupational Stress, Health Behavior, Safety Issues, Mental Health Wellness 1
Interventions
Total Worker Health Mindfulness Enhanced Program
Behavioral
Lead sponsor
Kerry Kuehl
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Salem, Oregon • Wilsonville, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Jul 21, 2026, 11:21 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Safety of Immediate Skin-to-Skin Contact After Vaginal Birth in Vigorous Late-Preterm Neonates

NCT03585192
View directory record Official record
Conditions
Safety Issues
Interventions
Skin Group, Warmer Group
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
Not listed
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Jul 21, 2026, 11:21 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Oral Mucosal Effects In Adult Smokers Associated With Two Nicotine Lozenge Formulations

NCT03087786
View directory record Official record
Conditions
Safety Issues
Interventions
Nicotine Bitartrate Lozenge 4mg, Nicotine Polacrilex 4Mg Lozenge
Drug
Lead sponsor
Niconovum USA
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 10, 2021 · Synced Jul 21, 2026, 11:21 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety and Pharmacokinetics of NP10679 in Normal Healthy Volunteers

NCT03565861
View directory record Official record
Conditions
Safety Issues
Interventions
Placebo, NP10679
Drug
Lead sponsor
Neurop Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Jul 21, 2026, 11:21 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety, Tolerability, and Pharmacokinetics of EQU-001 in Healthy Volunteers

NCT05004571
View directory record Official record
Conditions
Safety Issues
Interventions
EQU-001, Placebo
Drug
Lead sponsor
Equilibre Biopharmaceuticals B.V.
Industry
Eligibility
18 Years to 65 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Hialeah, Florida
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Jul 21, 2026, 11:21 AM EDT
Active, not recruiting Not applicable Interventional

Directed Use of REmote Patient Management System AMia to Achieve Prescribed Dry Weight

NCT04002440
View directory record Official record
Conditions
Efficacy, Safety Issues
Interventions
AMIA with SHARESOURCE Connectivity Platform, HomeChoice PRO
Combination Product · Device
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
2
States / cities
Chula Vista, California • San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 24, 2021 · Synced Jul 21, 2026, 11:21 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel

NCT05041699
View directory record Official record
Conditions
Pharmacokinetics, Safety Issues, Bleeding
Interventions
IPM Ring-105, IPM Ring-106
Combination Product
Lead sponsor
International Partnership for Microbicides, Inc.
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Portland, Oregon • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Jul 21, 2026, 11:21 AM EDT
Enrolling by invitation Not applicable Interventional

Pediatric Trauma Centers RE-AIM at Gun Safety

NCT06123611
View directory record Official record
Conditions
Firearm Injury, Safety Issues
Interventions
Adopting Comprehensive Training for FireArm Safety in Trauma centers
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
11 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Jul 21, 2026, 11:21 AM EDT
Completed No phase listed Observational

Safety Assessment of Femoropopliteal Endovascular Treatment With PAclitaxel-coated Devices (SAFE-PAD Study)

NCT04496544
View directory record Official record
Conditions
Peripheral Arterial Disease, Paclitaxel Adverse Reaction, Safety Issues
Interventions
Retrospective data collection
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
66 Years and older
Enrollment
168,553 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 8, 2024 · Synced Jul 21, 2026, 11:21 AM EDT