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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Safety Issues Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Same Day Discharge vs. Overnight Stay After Hysterectomy

NCT03627234
View directory record Official record
Conditions
Satisfaction, Safety Issues, Quality of Life
Interventions
Same Day Discharge, Overnight Stay
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 65 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 12, 2022 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Not applicable Interventional Results available

Aerosolization During Upper Endoscopy

NCT06006078
View directory record Official record
Conditions
Infectious, Gastro-Intestinal Disorder, Safety Issues
Interventions
Endoscopic Patient Facemask
Device
Lead sponsor
Anthony Lembo
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Jul 22, 2026, 5:05 PM EDT
Not listed Phase 1 Interventional

Phase 1 Study of Oral RH324 in Advanced Non-Small Cell Lung Cancer

NCT05580172
View directory record Official record
Conditions
Safety Issues
Interventions
RH324
Drug
Lead sponsor
ReHeva Biosciences,Inc.
Industry
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 16, 2022 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Buckle Me Up!: A Digital Emergency Department Discharge Intervention for Child Car Safety

NCT03799393
View directory record Official record
Conditions
Safety Issues, Injuries, Car Accident
Interventions
CIAS (Computer Intervention Authoring Software), Standard Printed Discharge Instructions
Behavioral
Lead sponsor
Lifespan
Other
Eligibility
Up to 21 Years
Enrollment
295 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 8, 2021 · Synced Jul 22, 2026, 5:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

FERTI-LILY Safety Study

NCT05529160
View directory record Official record
Conditions
Natural Conception, Label Comprehension, Device Usability, Safety Issues
Interventions
FERTI LILY Conception Cup
Device
Lead sponsor
Rosesta Medical BV
Industry
Eligibility
18 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated Apr 5, 2023 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Rectal Insert TAF/EVG Pre-Exposure Prophylaxis (RITE PrEP) Study

NCT06274398
View directory record Official record
Conditions
Safety Issues
Interventions
TAF/EVG rectal insert, Matching placebo rectal insert
Drug
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 59 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Jul 22, 2026, 5:05 PM EDT
Completed No phase listed Observational

Incidence/Magnitude-Haemorrhagic Progression-Cerebral Contusions and Identification (ID) of Safety Issues After Traumatic Brain Injury

NCT00124293
View directory record Official record
Conditions
Acquired Bleeding Disorder, Trauma
Interventions
activated recombinant human factor VII
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years to 85 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Plainsboro, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 26, 2017 · Synced Jul 22, 2026, 5:05 PM EDT
Enrolling by invitation Phase 1 Interventional

E-CEL UVEC Cells as an Adjunct Cell Therapy for the Arthroscopic Rotator Cuff Repair in Adults

NCT04057833
View directory record Official record
Conditions
Rotator Cuff Tears, Muscle Atrophy or Weakness, Tendon Rupture - Shoulder, Safety Issues
Interventions
E-CEL UVEC
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
45 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jul 22, 2026, 5:05 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Safety of Immediate Skin-to-Skin Contact After Vaginal Birth in Vigorous Late-Preterm Neonates

NCT03585192
View directory record Official record
Conditions
Safety Issues
Interventions
Skin Group, Warmer Group
Other
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
Not listed
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 2, 2019 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Emergency Manuals During Interprofessional Crisis Management: Are There Unintended Consequences?

NCT03006549
View directory record Official record
Conditions
Safety Issues
Interventions
Emergency Manual (Crisis Checklist)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2019 · Synced Jul 22, 2026, 5:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Safety-Enhancing Motor Vehicle Child Safety Seat

NCT06384989
View directory record Official record
Conditions
Motor Vehicle Injury, Safety Issues
Interventions
Child restraint system with load leg feature
Other
Lead sponsor
Minnesota HealthSolutions
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety and PK Multi-dose Study of TAF/EVG Vaginal Insert

NCT06087913
View directory record Official record
Conditions
Safety Issues
Interventions
TAF/EVG vaginal insert, Matching Placebo vaginal insert
Drug
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Safety and Tolerability of Soy Fiber

NCT04499482
View directory record Official record
Conditions
Safety Issues, Tolerance
Interventions
Food
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
70 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Not applicable Interventional Results available

Sick-Day Protocol to Improve Outcomes in Chronic Kidney Disease

NCT03141905
View directory record Official record
Conditions
Safety Issues, Chronic Kidney Diseases
Interventions
Sick-Day Protocol, Usual Care
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
Not listed
Enrollment
342 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Jul 22, 2026, 5:05 PM EDT
Withdrawn Not applicable Interventional

The HEALiX™ Intubated Patient (IP) Pilot Study

NCT04759066
View directory record Official record
Conditions
Device Ineffective, Safety Issues
Interventions
HEALiX
Device
Lead sponsor
Lancaster General Hospital
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 2, 2022 · Synced Jul 22, 2026, 5:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Survey of Housestaff Attitudes Toward Patient Care and Safety

NCT00845052
View directory record Official record
Conditions
Safety Issues, Patient Care
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
20 Years to 50 Years
Enrollment
674 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Safety of Gebauer's Pain Ease and Gebauer's Ethyl Chloride

NCT04207710
View directory record Official record
Conditions
Spray, Pain, Safety Issues
Interventions
Gebauer's Pain Ease Top Aerosol Mist Spray, Gebauer's Ethyl Chloride
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
Not listed
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 3, 2024 · Synced Jul 22, 2026, 5:05 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Corrections Work's Adverse Effects and a Total Worker Health Program to Enhance Well-being

NCT05608889
View directory record Official record
Conditions
Occupational Stress, Health Behavior, Safety Issues, Mental Health Wellness 1
Interventions
Total Worker Health Mindfulness Enhanced Program
Behavioral
Lead sponsor
Kerry Kuehl
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Salem, Oregon • Wilsonville, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Not applicable Interventional

Effect of Naringenin and Beta Carotene on Energy Expenditure

NCT04697355
View directory record Official record
Conditions
Energy Expenditure, Safety Issues, Glucose Metabolism
Interventions
naringenin and beta carotene
Dietary Supplement
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 8, 2021 · Synced Jul 22, 2026, 5:05 PM EDT
Active, not recruiting No phase listed Observational

A Chart Review to Evaluate the Safety and Efficacy of Phrenic Nerve Reconstruction for the Treatment of Diaphragmatic Paralysis

NCT06257589
View directory record Official record
Conditions
Diaphragm Issues, Diaphragm; Paralysis, Due to Accidental Section of Phrenic Nerve During Procedure, Breath Shortness, Diaphragmatic Paralysis
Interventions
Not listed
Lead sponsor
Advanced Reconstructive Surgery Alliance
Government
Eligibility
18 Years to 95 Years
Enrollment
700 participants
Timeline
2023 – 2026
U.S. locations
2
States / cities
Red Bank, New Jersey • Shrewsbury, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Safety and Pharmacokinetics of an Extract of Naringenin

NCT03582553
View directory record Official record
Conditions
Safety Issues, Pharmacokinetics
Interventions
Naringenin, Placebo
Dietary Supplement · Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

PK, Safety Study of 90-Day Use of Vaginal Rings Containing Dapivirine and Levonorgestrel

NCT05041699
View directory record Official record
Conditions
Pharmacokinetics, Safety Issues, Bleeding
Interventions
IPM Ring-105, IPM Ring-106
Combination Product
Lead sponsor
International Partnership for Microbicides, Inc.
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Portland, Oregon • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

An Interactive Web Platform to Teach Children Hunting, Shooting and Firearms Safety

NCT04622943
View directory record Official record
Conditions
Safety Issues, Injuries, Firearm Injury
Interventions
firearms safety, nutrition
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
10 Years to 12 Years
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Jul 22, 2026, 5:05 PM EDT
Completed Phase 1Phase 2 Interventional

Phase1/2a Study for IPG7236 in Patients With Advanced Solid Tumors

NCT05142592
View directory record Official record
Conditions
Safety Issues, Tolerability, Pharmacokinetics
Interventions
IPG7236
Drug
Lead sponsor
Nanjing Immunophage Biotech Co., Ltd
Industry
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Portland, Oregon • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Jul 22, 2026, 5:05 PM EDT