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Showing 1–17 of 17 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Salt-sensitive Hypertension Clear all

Conditions: Hypertension
Interventions: Salt loading, Hydrochlorothiazide (HCTZ); Procedure · Drug
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 65 Years
Enrollment: 124 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Lancaster, Pennsylvania

Conditions: Hypertension
Interventions: celecoxib (Celebrex), Placebo; Drug · Other
Lead sponsor: University of Delaware; Other
Eligibility: 22 Years to 50 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Hyperaldosteronism, Hypertension
Interventions: Not listed
Lead sponsor: National Heart, Lung, and Blood Institute (NHLBI); NIH
Eligibility: Not listed
Enrollment: 110 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1981 – 2001
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Hypertension
Interventions: High sodium diet and low sodium diet; Other
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 70 Years
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2021
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Hypertension
Interventions: Low sodium diet, high sodium diet; Other
Lead sponsor: Medical College of Wisconsin; Other
Eligibility: 30 Years to 65 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2030
U.S. locations: 1
States / cities: Milwaukee, Wisconsin

Conditions: High Blood Pressure, Salt; Excess, Inflammation
Interventions: Furosemide 40 mg; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Salt-sensitive Hypertension
Interventions: Valsartan, LCZ696; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 3
States / cities: Anaheim, California • Cypress, California • Glendale, California

Conditions: Hypertension, Stress, Psychological, Blood Pressure
Interventions: Prazosin, Placebo; Drug
Lead sponsor: Augusta University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Hypertension, Obesity, Stress, Psychological, Blood Pressure
Interventions: Irbesartan, Placebo; Drug · Other
Lead sponsor: Augusta University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2019
U.S. locations: 1
States / cities: Augusta, Georgia

Conditions: Salt-Sensitivity of Blood Pressure
Interventions: Furosemide (Diuretic), Hypertonic Saline Infusion; Drug · Other
Lead sponsor: University of Delaware; Other
Eligibility: 40 Years to 60 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2028
U.S. locations: 1
States / cities: Newark, Delaware

Conditions: Hypertension
Interventions: Not listed
Lead sponsor: National Institute on Aging (NIA); NIH
Eligibility: 40 Years to 70 Years
Enrollment: 96 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Hypertension Uncomplicated, Pre Hypertension
Interventions: High and low salt diets; Diagnostic Test
Lead sponsor: University of Minnesota; Other
Eligibility: 30 Years to 75 Years
Enrollment: 30 participants
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Genetics in Hypertension
Interventions: low sodium diet, high sodium diet, renal plasma flow, SIEA collection; Other · Procedure
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 50 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hypertension
Interventions: Para-aminohippuric Acid, Angiotensin II; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Salt Sensitivity of Blood Pressure, Hypertension
Interventions: High Salt Diet, Low Salt Diet; Dietary Supplement
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 50 Years to 70 Years
Enrollment: 281 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 2
States / cities: Birmingham, Alabama • Chicago, Illinois

Conditions: Salt Sensitivity of Blood Pressure, High Blood Pressure, Inflammation, Renin-Angiotensin-Aldosterone System
Interventions: 2-hydroxybenzylamine, Placebo; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Salt-sensitive Hypertension
Interventions: Fenoldopam; Drug
Lead sponsor: Georgetown University; Other
Eligibility: 18 Years to 55 Years
Enrollment: 45 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2006
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

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Salt Loading and Thiazide Intervention Study

The Role of COX-2 Inhibition in Salt Sensitivity of Blood Pressure

Effects of Salt Intake on the Nervous Systems of Patients With Salt-Sensitive High Blood Pressure

Blood Pressure Response to Sodium in the Diet

Renal Metabolism in Salt-sensitive Human Blood Pressure

Salt-Sensitivity and Immunity Cell Activation

Assessment of LCZ696 and Valsartan in Asian Patients With Salt-sensitive Hypertension

Effectiveness of Prazosin on the Urinary Sodium Excretion Response to Mental Stress

Effectiveness of Avapro in Obese Normotensive/Hypertensive African Americans

Forebrain Electroneutral Transporters in Salt-sensitive Hypertension: an MRI Study

Salt Study: Inhibited Breathing Pattern and Sodium Inhibitors in Sodium Sensitivity of Blood Pressure

A Biomarker to Detect Salt Sensitivity

Beta-2 Adrenergic Receptor Polymorphic Variants: An Endotype of Salt Sensitive Hypertension (Beta2AR).

Evaluation of Lysine-Specific Demethylase 1

CARDIA-Salt Sensitivity of Blood Pressure (SSBP)

Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in Humans

Intervention Study to Compare the Natriuretic Effects of Enalapril on Low and High Salt Diet