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ClinicalTrials.gov public records Last synced Sep 30, 2026, 6:59 AM EDT

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Showing 25–48 of 63 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Scar, Hypertrophic Clear all
Active, not recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Randomized Controlled Trial Examining the Efficacy of Botulinum Toxin in Biopsy Scar Minimization

NCT05478551
View directory record Official record
Conditions
Scar, Hypertrophic Scar
Interventions
Botulinum Toxin, Normal saline
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Sep 30, 2026, 6:59 AM EDT
Withdrawn Not applicable Interventional

Efficacy of Spray Silicone in Alteration of Burn Scar

NCT01075165
View directory record Official record
Conditions
Burn Scar
Interventions
silicone spray, saline spray
Other
Lead sponsor
United States Army Institute of Surgical Research
Federal
Eligibility
18 Years to 60 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 4, 2015 · Synced Sep 30, 2026, 6:59 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy and Tolerability of a Hybrid Fractional Laser for the Treatment of Acne Scars in Patients With Skin of Color

NCT05362929
View directory record Official record
Conditions
Acne Scars - Mixed Atrophic and Hypertrophic, Hyperpigmentation, Laser-Induced Hyperpigmentation
Interventions
Sciton Halo
Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Elmsford, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 30, 2026, 6:59 AM EDT
Not listed Phase 2 Interventional

Treatment of Hypopigmented Scars With Bimatoprost

NCT06122090
View directory record Official record
Conditions
Scars, Hypopigmented Scar, Hypopigmented Skin, Burn Scar, Scarring, Cicatrix, Hypertrophic, Cicatrix, Pigmentation Disorder, Burns Laser
Interventions
Bimatoprost, Saline
Drug
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Sep 30, 2026, 6:59 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The MIRIA Acne Scar Study

NCT05597267
View directory record Official record
Conditions
Acne Scars - Mixed Atrophic and Hypertrophic
Interventions
MIRIA Laser
Device
Lead sponsor
AVAVA, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
3
States / cities
Miami, Florida • Waltham, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2025 · Synced Sep 30, 2026, 6:59 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin

NCT02630303
View directory record Official record
Conditions
Fibrosis, Scarring, Scar, Wounds, Injuries, Keloid, Cicatrix, Hypertrophic
Interventions
LED-RL Phototherapy, Mock Therapy
Device
Lead sponsor
Jared Jagdeo, MD, MS
Federal
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Mar 31, 2017 · Synced Sep 30, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

Investigation of a Novel Silicone Dressing to Maximize the Outcomes of Scar Revision Procedures (IMPROVE)

NCT01430130
View directory record Official record
Conditions
Hypertrophic
Interventions
embrace device
Device
Lead sponsor
Neodyne Biosciences, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 28, 2014 · Synced Sep 30, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

Pilot Study of a Novel 532nm KTP Laser for the Treatment of Fresh Surgical Scars

NCT01789346
View directory record Official record
Conditions
Scar, Surgical Scar, Cicatrix, Cicatrix, Hypertrophic, Keloid
Interventions
532nm KTP, 595nm PDL
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 21, 2023 · Synced Sep 30, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

Tripeptide/Hexapeptide Topical and Hybrid Laser Treatment for Acne Scarring

NCT04606134
View directory record Official record
Conditions
Acne Scars - Mixed Atrophic and Hypertrophic
Interventions
Hybrid fractional laser, Alastin Regenerating Skin Nectar with TriHex Technology, Cetaphil face cream
Device · Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Sep 30, 2026, 6:59 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

A Study to Evaluate the Effectiveness and Safety of RXI 109 on the Outcome of Revised Hypertrophic Scars

NCT02246465
View directory record Official record
Conditions
Hypertrophic Scar
Interventions
RXI-109
Drug
Lead sponsor
RXi Pharmaceuticals, Corp.
Industry
Eligibility
21 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
5
States / cities
Beverly Hills, California • Lake Worth, Florida • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2018 · Synced Sep 30, 2026, 6:59 AM EDT
Completed No phase listed Observational

Characterization of Dyschromic Hypertrophic Scar

NCT04619589
View directory record Official record
Conditions
Burn Scar, Hypertrophic Scar, Hyperpigmentation, Hypopigmented Scar
Interventions
Not listed
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 3, 2023 · Synced Sep 30, 2026, 6:59 AM EDT
Withdrawn Not applicable Interventional

Pain and Itch Reduction in Burn Scars Treated With Fractional CO2 Laser

NCT04364217
View directory record Official record
Conditions
Hypertrophic Scar, Burn Scar
Interventions
Luminis ultrapulse fractional ablative carbon dioxide laser
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 31, 2025 · Synced Sep 30, 2026, 6:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treatment of Fibrotic Scars With Rapid Acoustic Pulse (RAP) Device

NCT04702529
View directory record Official record
Conditions
Scars, Hypertrophic
Interventions
Treatment of hypertrophic scars (Soliton's Rapid Acoustic Pulse (RAP) Device)
Device
Lead sponsor
Soliton
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 24, 2024 · Synced Sep 30, 2026, 6:59 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Laser Treatment for the Improvement of Scars and Scleroderma

NCT04567537
View directory record Official record
Conditions
Scars, Scleroderma
Interventions
Laser Treatment
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Sep 30, 2026, 6:59 AM EDT
Completed Not applicable Interventional

"A Clinical Study Investigating the Effectiveness of OTC Scar-management Modalities"

NCT04169490
View directory record Official record
Conditions
Scar, Keloid, Hypertrophic Scar, Cicatrix
Interventions
Placebo Cream Base Emulsion Moisturizer, FS2 Emulsion Moisturizer, Active Comparator Onion Skin Extract Gel (Mederma), Active Comparator Silicone Gel (Kelo-Cote), Active Comparator Silicone Gel (Kelo-Cote) + FS2 Emulsion Moisturizer
Other
Lead sponsor
The Center for Clinical and Cosmetic Research
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Aventura, Florida
Source: ClinicalTrials.gov public record
Updated Mar 21, 2022 · Synced Sep 30, 2026, 6:59 AM EDT
Not listed Phase 1 Interventional Accepts healthy volunteers

Phase 1 Study of HF-LED-RL in Fitzpatrick Skin Types I to III

NCT03433222
View directory record Official record
Conditions
Skin Diseases, Keloid, Scar, Fibrosis, Hypertrophic Skin
Interventions
HF-LED-RL Phototherapy, Mock Therapy
Device
Lead sponsor
VA Northern California Health Care System
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2018 · Synced Sep 30, 2026, 6:59 AM EDT
Withdrawn Not applicable Interventional

Early Carbon Dioxide Laser Therapy for Alleviation of Incisional Scar Burden

NCT03306628
View directory record Official record
Conditions
Skin Scarring
Interventions
CO2 Laser Administration
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years to 80 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Sep 30, 2026, 6:59 AM EDT
Completed Not applicable Interventional

Effects of Pulsed Dye and CO2 Laser in Treatment of Hypertrophic Burn Scars.

NCT04769089
View directory record Official record
Conditions
Hypertrophic Scar
Interventions
Treatment with Pulse Dye Laser, Treatment with CO2 Laser, Treatment with combination of pulse dye laser and CO2 laser., Control
Procedure · Other
Lead sponsor
The Metis Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 24, 2021 · Synced Sep 30, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

A Study of a Novel Silicone Dressing to Minimize Scar Formation

NCT01399099
View directory record Official record
Conditions
Hypertrophic
Interventions
embrace device
Device
Lead sponsor
Neodyne Biosciences, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
13
States / cities
Atherton, California • Bakersfield, California • Danville, California + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Sep 30, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

Randomized Controlled Trial of Subcuticular Skin Closure Versus Steri-strip S Closure

NCT00727025
View directory record Official record
Conditions
Breast Hypertrophy, Abdominal Elastosis, Breast Reconstruction
Interventions
wound closure device (Steri-Strip™)
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Sep 30, 2026, 6:59 AM EDT
Not listed No phase listed Observational

Keloid Radiation Registry

NCT01457079
View directory record Official record
Conditions
Keloid
Interventions
Not listed
Lead sponsor
Tirgan, Michael H., M.D.
Individual
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Sep 30, 2026, 6:59 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Clinical Efficacy And Safety Of SkinStylus Microneedling System

NCT03366194
View directory record Official record
Conditions
Cicatrix, Hypertrophic
Interventions
SkinStylus Sterilock System
Device
Lead sponsor
Esthetic Education LLC
Industry
Eligibility
23 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Sep 30, 2026, 6:59 AM EDT
Completed Not applicable Interventional Results available

Fractional Radiofrequency for the Treatment and Reduction of Acne Scars and Wrinkles

NCT04057768
View directory record Official record
Conditions
Acne Scars - Mixed Atrophic and Hypertrophic, Wrinkle
Interventions
Venus Viva
Device
Lead sponsor
Venus Concept
Industry
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 29, 2021 · Synced Sep 30, 2026, 6:59 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring Prevention

NCT03795116
View directory record Official record
Conditions
Fibrosis, Skin Scarring, Skin Wound, Hypertrophic Scar, Scar, Keloid
Interventions
LED-RL phototherapy, Mock irradiation
Device
Lead sponsor
State University of New York - Downstate Medical Center
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2022 · Synced Sep 30, 2026, 6:59 AM EDT