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Showing 1–24 of 94 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Scoliosis Idiopathic Clear all
Not listed Phase 2 Interventional Accepts healthy volunteers

Incobotulinumtoxin A and Yoga-like Isometric Exercise in Adolescent Idiopathic Lumbar Scoliosis

NCT04922983
View directory record Official record
Conditions
Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis; Lumbar Region
Interventions
Botulinum toxin type A, Isometric Yoga-like exercise, Placebo
Drug · Behavioral
Lead sponsor
Manhattan Physical Medicine and Rehabilitation, LLP
Other
Eligibility
14 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Manhattan, New York
Source: ClinicalTrials.gov public record
Updated Oct 18, 2023 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Massage Therapy After Thoracic or Lumbar Surgery

NCT06424158
View directory record Official record
Conditions
Scoliosis; Adolescence, Adolescent Idiopathic Scoliosis, Thoracic Region, Adolescent Idiopathic Scoliosis, Lumbar Region
Interventions
Massage Therapy
Other
Lead sponsor
Cook Children's Health Care System
Other
Eligibility
7 Years to 19 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Brace Monitoring for Adolescent Idiopathic Scoliosis (AIS)

NCT03292601
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
NYRC Brace Scoliosis Monitor
Device
Lead sponsor
Columbia University
Other
Eligibility
8 Years to 17 Years · Female only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Jul 21, 2026, 6:11 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

3-D Correction of Adolescent Idiopathic Scoliosis (AIS) With Differential Metals

NCT05631821
View directory record Official record
Conditions
Juvenile and Adolescent Idiopathic Scoliosis
Interventions
differential rod bending with rod contours (MESA Spinal System)
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
10 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 1, 2022 · Synced Jul 21, 2026, 6:11 PM EDT
Enrolling by invitation Phase 4 Interventional

Prospective Opioid-Free AIS Fusion

NCT06935331
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS)
Interventions
Opioid-Free/Opioid-Avoidant, Opioid-Containing
Drug
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
10 Years to 20 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Jul 21, 2026, 6:11 PM EDT
Completed Phase 4 Interventional

IV Methadone Vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Undergoing Idiopathic Scoliosis Correction

NCT05730920
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Juvenile Idiopathic Scoliosis
Interventions
Methadone, Liposomal bupivacaine (LB, Exparel)
Drug
Lead sponsor
Dr. Casey Stondell, MD
Other
Eligibility
11 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Jul 21, 2026, 6:11 PM EDT
Completed Not applicable Interventional

Coping After Pediatric Scoliosis Surgery

NCT04063670
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Video Intervention, Control
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
11 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Yoga for Back Pain in Adolescent Scoliosis

NCT06242821
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent Treatment, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis
Interventions
Standard of Care (SOC), Yoga
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
10 Years to 20 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Jul 21, 2026, 6:11 PM EDT
Not yet recruiting No phase listed Observational

A Retrospective Review: Outcomes of the REFLECT™ System for Idiopathic Scoliosis

NCT07589023
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Scoliosis Correction System
Device
Lead sponsor
Globus Medical Inc
Industry
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jul 21, 2026, 6:11 PM EDT
Completed Phase 4 Interventional

Surgical Outcomes Using Variable Rod Diameters in the Treatment of Idiopathic Scoliosis

NCT00510575
View directory record Official record
Conditions
Scoliosis
Interventions
Spinal rod
Device
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
11 Years to 18 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Rethinking Rigidity: Development of a 3D-Printed Scoliosis Brace With Varying Flexibility

NCT06785207
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent Treatment
Interventions
3D-printed scoliosis brace
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
8 Years to 18 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Houston, Texas • The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jul 21, 2026, 6:11 PM EDT
Completed No phase listed Observational

Return to Sport After Posterior Spinal Fusion

NCT03513120
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Posterior Spinal Fusion
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 18, 2020 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Phase 4 Interventional

Dysport ® as an Adjunctive Treatment to Bracing in the Management of Adolescent Idiopathic Scoliosis

NCT03935295
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
AbobotulinumtoxinA, Placebos, Custom Thoracolumbosacral Orthosis
Drug · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
10 Years to 16 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced Jul 21, 2026, 6:11 PM EDT
Completed Not applicable Interventional Results available

Vertebral Body Tethering Outcomes for Pediatric Idiopathic Scoliosis

NCT03194568
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Anterior Vertebral Tether
Device
Lead sponsor
Patrick Cahill, MD
Other
Eligibility
8 Years to 16 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 22, 2024 · Synced Jul 21, 2026, 6:11 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Yoga for Adolescent Idiopathic Scoliosis (AIS) Patients

NCT06003010
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Spinal Fusion
Interventions
Yoga
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
10 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 31, 2023 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Phase 3 Interventional

The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery

NCT07561827
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
Interventions
Ropivacaine Hydrocloride
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 21, 2026, 6:11 PM EDT
Not listed No phase listed Observational

Evaluation of the Providence Nighttime Brace for the Treatment of Adolescence Idiopathic Scoliosis

NCT02227537
View directory record Official record
Conditions
Adolescence Idiopathic Scoliosis
Interventions
Providence Nighttime Bracing System
Device
Lead sponsor
OrthoGeorgia
Other
Eligibility
10 Years to 14 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Macon, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 20, 2015 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Psychological Assessment of Scoliosis Patients Undergoing Surgical Management

NCT05774002
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS), Mental Health
Interventions
Aims to Decrease Anxiety and Pain Treatment (ADAPT)
Behavioral
Lead sponsor
Montefiore Medical Center
Other
Eligibility
10 Years to 19 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jul 21, 2026, 6:11 PM EDT
Completed Not applicable Interventional Results available

Anesthesia and Motor Evoked Potential (MEP) Recruitment

NCT02199314
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Desflurane
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 21, 2020 · Synced Jul 21, 2026, 6:11 PM EDT
Recruiting Not applicable Interventional

Open-label Placebo (COLP) for Pain in Adolescent Idiopathic Scoliosis (AIS) Surgery+Surgical Treatment of Idiopathic Scoliosis

NCT06365892
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS)
Interventions
open-label placebo, Treatment as usual
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years to 18 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Jul 21, 2026, 6:11 PM EDT
Completed No phase listed Observational

The Treatment of Progressive Early Onset Spinal Deformities: A Multi-Center Outcome Study

NCT02299362
View directory record Official record
Conditions
Early Onset Scoliosis, Congenital Spinal Deformities, Infantile Idiopathic Scoliosis, Neuromuscular Spinal Deformity, Syndromic Spinal Deformity, Thoracic Insufficiency Syndrome
Interventions
Not listed
Lead sponsor
Growing Spine Study Group
Other
Eligibility
1 Day to 18 Years
Enrollment
2,602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2020
U.S. locations
19
States / cities
Little Rock, Arkansas • Los Angeles, California • San Diego, California + 16 more
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Jul 21, 2026, 6:11 PM EDT
Completed Not applicable Interventional Results available

Green Sun Medical Dynamic Scoliosis Brace

NCT03641469
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Green Sun Dynamic Brace
Device
Lead sponsor
Green Sun medical
Industry
Eligibility
10 Years to 15 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
7
States / cities
Los Angeles, California • Pasadena, California • Sacramento, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Jul 21, 2026, 6:11 PM EDT
Completed Early Phase 1 Interventional

Medrol Dose Packs for Post-Operative Pain Control

NCT06453083
View directory record Official record
Conditions
Pain
Interventions
Placebo, Medrol
Drug
Lead sponsor
University of Utah
Other
Eligibility
10 Years to 21 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Jul 21, 2026, 6:11 PM EDT
Active, not recruiting No phase listed Observational

3D Body Surface Modeling for Scoliosis Monitoring

NCT05697939
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
NSite 3D Scanning
Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
10 Years to 18 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Jul 21, 2026, 6:11 PM EDT