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ClinicalTrials.gov public records Last synced Oct 6, 2026, 2:02 PM EDT

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Showing 1–24 of 96 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Scoliosis Idiopathic Clear all
Completed No phase listed Observational Accepts healthy volunteers

Gait and Postural Stability Assessment in Children With Idiopathic Scoliosis Undergoing Posterior Spine Instrumentation

NCT01109082
View directory record Official record
Conditions
Scoliosis
Interventions
posterior spine fusion
Procedure
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
1 Year to 20 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 19, 2013 · Synced Oct 6, 2026, 2:02 PM EDT
Recruiting Phase 4 Interventional

Dysport ® as an Adjunctive Treatment to Bracing in the Management of Adolescent Idiopathic Scoliosis

NCT03935295
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
AbobotulinumtoxinA, Placebos, Custom Thoracolumbosacral Orthosis
Drug · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
10 Years to 16 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 6, 2026, 2:02 PM EDT
Completed No phase listed Observational

Bracing Compliance and Personality Traits: A Compliance Assessment Program for Scoliosis and Clubfeet

NCT02755766
View directory record Official record
Conditions
Clubfeet, Adolescent Idiopathic Scoliosis
Interventions
Not listed
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
1 Day to 99 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Oct 6, 2026, 2:02 PM EDT
Completed Not applicable Interventional Results available

Scoliosis-Specific Exercises for At-Risk AIS Curves

NCT02807545
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Scoliosis Specific Exercises
Behavioral
Lead sponsor
Texas Scottish Rite Hospital for Children
Other
Eligibility
10 Years to 17 Years
Enrollment
98 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
6
States / cities
Louisville, Kentucky • Baltimore, Maryland • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Oct 6, 2026, 2:02 PM EDT
Recruiting Not applicable Interventional

Studying Melatonin and Recovery in Teens

NCT06093477
View directory record Official record
Conditions
Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital, Kyphosis, Spondylolisthesis, Pectus Surgery, Hip Surgery
Interventions
Fast-Dissolve Melatonin Pill, Fast-Dissolve Placebo Pill
Dietary Supplement · Other
Lead sponsor
Stanford University
Other
Eligibility
12 Years to 18 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 6, 2026, 2:02 PM EDT
Not yet recruiting Phase 4 Interventional

Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients

NCT06023043
View directory record Official record
Conditions
Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
Interventions
Dexamethasone
Drug
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
9 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 6, 2026, 2:02 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Study of 3D Scanning for Adolescent Scoliosis

NCT06035952
View directory record Official record
Conditions
Scoliosis
Interventions
3D topographical scan
Diagnostic Test
Lead sponsor
NSite Medical
Industry
Eligibility
10 Years to 18 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Palo Alto, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 13, 2023 · Synced Oct 6, 2026, 2:02 PM EDT
Completed Not applicable Interventional Results available

Anesthesia and Motor Evoked Potential (MEP) Recruitment

NCT02199314
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Desflurane
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
12 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 22, 2020 · Synced Oct 6, 2026, 2:02 PM EDT
Recruiting Not applicable Interventional

REFLECT Scoliosis System Post Approval Study

NCT06298812
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
REFLECT Scoliosis Correction System
Device
Lead sponsor
Globus Medical Inc
Industry
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2032
U.S. locations
2
States / cities
Rochester, Minnesota • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 6, 2026, 2:02 PM EDT
Terminated No phase listed Observational

Robotic vs. Freehand Corrective Surgery for Pediatric Scoliosis

NCT02084264
View directory record Official record
Conditions
Scoliosis
Interventions
Not listed
Lead sponsor
Mazor Robotics
Industry
Eligibility
10 Years to 21 Years
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
4
States / cities
San Diego, California • Orlando, Florida • Atlanta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 6, 2026, 2:02 PM EDT
Completed Not applicable Interventional

Anesthetic Optimization in Scoliosis Surgery

NCT02481570
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Respiratory Depression, Postoperative Pain
Interventions
pharmacokinetic simulation
Other
Lead sponsor
University of Florida
Other
Eligibility
10 Years to 18 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Oct 6, 2026, 2:02 PM EDT
Enrolling by invitation Phase 4 Interventional

Prospective Opioid-Free AIS Fusion

NCT06935331
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS)
Interventions
Opioid-Free/Opioid-Avoidant, Opioid-Containing
Drug
Lead sponsor
OrthoCarolina Research Institute, Inc.
Other
Eligibility
10 Years to 20 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 6, 2026, 2:02 PM EDT
Completed Phase 4 Interventional Results available

Skeletal Muscle and Adipose Tissue Study

NCT03190668
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Bolus dose of Cefazolin, Continuous Cefazolin drip, Paraspinal muscle microdialysis catheters, Subcutaneous microdialysis catheters
Drug · Device
Lead sponsor
University of Florida
Other
Eligibility
12 Years to 20 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 11, 2023 · Synced Oct 6, 2026, 2:02 PM EDT
Completed Not applicable Interventional

Adolescent Idiopathic Scoliosis (AIS) Gold Standard for Blood Loss

NCT03990376
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Radioisotope I-131-labeled albumin
Other
Lead sponsor
Emory University
Other
Eligibility
10 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 11, 2021 · Synced Oct 6, 2026, 2:02 PM EDT
Completed Not applicable Interventional

Evaluate Initial Safety of the HemiBridge™ System in Guided Spinal Growth Treatment of Progressive Idiopathic Scoliosis

NCT01465295
View directory record Official record
Conditions
Scoliosis
Interventions
Mechanical hemiepiphysiodesis using the HemiBridge System
Device
Lead sponsor
SpineForm LLC
Industry
Eligibility
10 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
2
States / cities
Cincinnati, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 5, 2018 · Synced Oct 6, 2026, 2:02 PM EDT
Completed Phase 4 Interventional

IV Methadone Vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Undergoing Idiopathic Scoliosis Correction

NCT05730920
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Juvenile Idiopathic Scoliosis
Interventions
Methadone, Liposomal bupivacaine (LB, Exparel)
Drug
Lead sponsor
Dr. Casey Stondell, MD
Other
Eligibility
11 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 6, 2026, 2:02 PM EDT
Recruiting No phase listed Observational

Analysis of Prognostic Cell Signaling Factors in Adolescent Idiopathic Scoliosis

NCT02315729
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 13 Years · Female only
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 6, 2026, 2:02 PM EDT
Completed Not applicable Interventional Results available

Green Sun Medical Dynamic Scoliosis Brace

NCT03641469
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Green Sun Dynamic Brace
Device
Lead sponsor
Green Sun medical
Industry
Eligibility
10 Years to 15 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
7
States / cities
Los Angeles, California • Pasadena, California • Sacramento, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 6, 2026, 2:02 PM EDT
Not listed Not applicable Interventional

Massage Therapy After Thoracic or Lumbar Surgery

NCT06424158
View directory record Official record
Conditions
Scoliosis; Adolescence, Adolescent Idiopathic Scoliosis, Thoracic Region, Adolescent Idiopathic Scoliosis, Lumbar Region
Interventions
Massage Therapy
Other
Lead sponsor
Cook Children's Health Care System
Other
Eligibility
7 Years to 19 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 23, 2024 · Synced Oct 6, 2026, 2:02 PM EDT
Completed Phase 4 Interventional

Continuous Local Infusion of Anesthetic at the Incisional Site for Scoliosis Surgery

NCT00508066
View directory record Official record
Conditions
Scoliosis
Interventions
Bupivacaine, Normal Saline
Drug
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
8 Years to 18 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 25, 2013 · Synced Oct 6, 2026, 2:02 PM EDT
Completed Phase 4 Interventional Results available

Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia

NCT01325493
View directory record Official record
Conditions
Idiopathic Scoliosis, Spondylolisthesis
Interventions
Ketamine, Normal Saline
Drug
Lead sponsor
Julia Finkel
Other
Eligibility
10 Years to 18 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jan 14, 2016 · Synced Oct 6, 2026, 2:02 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Advanced SPinal Innovations With Robotics and Enabling Technology Registry

NCT05071144
View directory record Official record
Conditions
Spine Deformity, Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis, Spondylolisthesis, Congenital Scoliosis, Neuromuscular Scoliosis
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
0 Years to 21 Years
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2031
U.S. locations
10
States / cities
Los Angeles, California • Aurora, Colorado • Atlanta, Georgia + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 6, 2026, 2:02 PM EDT
Recruiting Not applicable Interventional

Open-label Placebo (COLP) for Pain in Adolescent Idiopathic Scoliosis (AIS) Surgery+Surgical Treatment of Idiopathic Scoliosis

NCT06365892
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS)
Interventions
open-label placebo, Treatment as usual
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years to 18 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 6, 2026, 2:02 PM EDT
Recruiting Not applicable Interventional

A Study to Evaluate a New Semi-rigid Brace, the RESILIENT Brace by Thinks Works, as a Way to Limit Curve Worsening in Kids With Idiopathic Scoliosis.

NCT07574632
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
The RESILIENT scoliosis brace system
Device
Lead sponsor
Thinks Works, PBC
Industry
Eligibility
9 Years to 16 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 6, 2026, 2:02 PM EDT