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Showing 1–24 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Seroma Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Study to Evaluate the Performance of a Sustained Vacuum System

NCT04554407
View directory record Official record
Conditions
Seroma as Procedural Complication, Hematoma Postoperative
Interventions
SOMAVAC® 100 Sustained Vacuum System
Device
Lead sponsor
SOMAVAC Medical Solutions
Industry
Eligibility
21 Years and older · Female only
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Drain Placement for Seroma Prevention After Mammosite/SAVI Catheter Removal

NCT02390661
View directory record Official record
Conditions
Infected Seroma After Surgical Procedure
Interventions
Penrose drain placement
Device
Lead sponsor
Michigan State University
Other
Eligibility
45 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Lansing, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 11, 2019 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Results available

Fibrin Melanoma Axillary Node Study in Patients With Melanoma

NCT00504582
View directory record Official record
Conditions
Melanoma
Interventions
Fibrin Sealant
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Phase 2 Interventional

Doxycycline Use in Post-Operative Seromas

NCT07498010
View directory record Official record
Conditions
Seroma
Interventions
Doxycycline
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Efficacy and Safety of ARTISS for Flap Adherence in Abdominoplasty

NCT01112735
View directory record Official record
Conditions
Seroma, Hematoma
Interventions
FS VH S/D 4 s-apr (= two-component fibrin sealant, double virus inactivated, made from pooled human plasma), Standard of care
Biological · Procedure
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
6
States / cities
Beverly Hills, California • Fort Lauderdale, Florida • Miami, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Investigating the Use of Intravenous Tranexamic Acid in Gender Affirming Mastectomy

NCT05794321
View directory record Official record
Conditions
Postoperative Hematoma, Postoperative Seroma
Interventions
Intravenous TXA
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2032
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Withdrawn Not applicable Interventional

Doxycycline Versus Standard Care to Prevent Seroma Formation

NCT01188954
View directory record Official record
Conditions
Seroma
Interventions
doxycycline, No intervention
Drug · Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Staten Island, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Results available

Prevention of Seroma Formation and Wound Complications Using NPWT Devices

NCT02147288
View directory record Official record
Conditions
Seroma, Wound Dehiscence, Wound Infection
Interventions
Renasys*GO Negative Pressure Wound Therapy System
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 29, 2017 · Synced Jul 21, 2026, 2:19 PM EDT
Withdrawn Not applicable Interventional

Trial Evaluating Use of Arista in Total Thyroidectomy

NCT02568085
View directory record Official record
Conditions
Thyroidectomy, Seroma
Interventions
Arista
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Jul 21, 2026, 2:19 PM EDT
Completed No phase listed Observational

Retrospective Analysis of Veritas in Breast Reconstruction

NCT01454713
View directory record Official record
Conditions
Seroma, Necrosis, Infection
Interventions
Not listed
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
3
States / cities
San Diego, California • Troy, Michigan • Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Arista for ALT Donor Sites to Reduce Drain Output

NCT02477774
View directory record Official record
Conditions
Seroma
Interventions
ARISTA
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Jul 21, 2026, 2:19 PM EDT
Terminated Phase 4 Interventional Results available

TXA in the Reduction of Post-Op Hematoma and Seroma in Patients Undergoing Panniculectomy or Abdominoplasty

NCT04902950
View directory record Official record
Conditions
Panniculectomy, Abdominoplasty
Interventions
Tranexamic acid, Saline
Drug
Lead sponsor
The Reading Hospital and Medical Center
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
West Reading, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 24, 2023 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Results available

Negative Pressure Wound Therapy After Cesarean Delivery

NCT01637870
View directory record Official record
Conditions
Major Puerperal Infection, Postpartum, Wound Complications, Wound Seroma, Caesarean Section Wound Separation, Wound Infection
Interventions
Prevena negative pressure wound system
Device
Lead sponsor
Abbey Hardy-Fairbanks
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 17, 2018 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effects of Post-Operative Interventions on Surgical Site Occurrences in AWR

NCT04906408
View directory record Official record
Conditions
Abdomen Hernia
Interventions
Prevena, Prineo, Traditional
Device · Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Results available

The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions

NCT01450631
View directory record Official record
Conditions
Post-operative Complications, Surgical Site Infection, Surgical Wound Infection
Interventions
Prevena™ Incision Management System (PIMS), Standard-of-care Dressing
Device
Lead sponsor
KCI USA, Inc
Industry
Eligibility
18 Years and older · Female only
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Jul 21, 2026, 2:19 PM EDT
Recruiting Not applicable Interventional

Steri-Strip Application Versus Standard Wound Closure for Cesarean Section Incisions

NCT07686913
View directory record Official record
Conditions
Cesarean Section, Surgical Site Infection, Wound Dehiscence, Seroma
Interventions
Steri-Strip™ Skin Closures, Standard Cesarean Wound Closure
Device · Procedure
Lead sponsor
Riverside University Health System Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Moreno Valley, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Terminated Not applicable Interventional

Progressive Tension Sutures in Gender Affirming Mastectomy

NCT04818580
View directory record Official record
Conditions
Hematoma, Seroma
Interventions
Progressive Tension Sutures
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older · Male only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 29, 2023 · Synced Jul 21, 2026, 2:19 PM EDT
Terminated Not applicable Interventional Results available

Fibrin Sealant in Preventing Fluid Build Up During Surgery in Patients Undergoing Breast Reconstruction

NCT01649505
View directory record Official record
Conditions
Breast Cancer, Perioperative/Postoperative Complications
Interventions
fibrin sealant (Beriplast P, TISSEEL VH), breast reconstruction
Drug · Procedure
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional

Evaluating the Use of Fibrin Tissue Adhesive in Melanoma Patients

NCT00506311
View directory record Official record
Conditions
Melanoma
Interventions
Fibrin Sealant
Drug
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 1, 2012 · Synced Jul 21, 2026, 2:19 PM EDT
Not listed Phase 3 Interventional

Application Of Autologous Blood Products During Modified Radical Mastectomy

NCT00802477
View directory record Official record
Conditions
Mastectomy
Interventions
Application of autologous blood products., Standard Modified Radical Mastectomy
Procedure
Lead sponsor
Marshall University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Huntington, West Virginia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2011 · Synced Jul 21, 2026, 2:19 PM EDT
Active, not recruiting Phase 2 Interventional

Axillary Reverse Mapping

NCT00572481
View directory record Official record
Conditions
Cancer of the Breast
Interventions
Axillary Reverse Mapping
Procedure
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Terminated Phase 4 Interventional Results available

Impact of Topical Tranexamic Acid in Breast Reconstruction

NCT05807074
View directory record Official record
Conditions
Breast Cancer
Interventions
Tranexamic Acid, Saline
Drug · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications

NCT03773575
View directory record Official record
Conditions
Amputation, Amputation; Postoperative, Sequelae, Wound Dehiscence, Seroma, Wound Infection, Surgical, Lymph Leakage
Interventions
PREVENA™ PEEL & PLACE™ Dressing Kit
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Valhalla, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Jul 21, 2026, 2:19 PM EDT
Completed Not applicable Interventional

The Effect of Arista on Post-Operative Bleeding and Wound Drainage Following Mastectomy

NCT03647930
View directory record Official record
Conditions
Seroma
Interventions
Microporous Polysaccharide Hemospheres (MPH)
Device
Lead sponsor
Memorial Health University Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Savannah, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 26, 2018 · Synced Jul 21, 2026, 2:19 PM EDT