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ClinicalTrials.gov public records Last synced Oct 20, 2026, 11:45 PM EDT

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Showing 1–24 of 127 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sexual Risk Reduction Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Young Men's Health Project Targeting HIV Risk Reduction and Substance Abuse

NCT03577301
View directory record Official record
Conditions
HIV Infections
Interventions
Clinic-based Delivery, Remote Delivery, Multi-modal Delivery
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
15 Years to 24 Years · Male only
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
3
States / cities
Miami, Florida • Detroit, Michigan • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acceptability, Feasibility, and Preliminary Impact of a Web-based, HIV Prevention Toolkit With Cisgender Male Couples in Lima, Peru

NCT05873855
View directory record Official record
Conditions
HIV Infections, Hiv, Sexually Transmitted Infections (Not HIV or Hepatitis), Sexually Transmitted Diseases, Sexual Behavior, Risk Reduction
Interventions
Para ti, para mi, para nosotros (P3), Waitlist Control Para ti, para mi, para nosotros (P3)
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older · Male only
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Phase 3 Interventional

A Study of Acyclovir to Help Prevent HIV Infection in People With Genital Herpes

NCT00076232
View directory record Official record
Conditions
HIV Infections, HIV Seronegativity, Herpes Genitalis
Interventions
Acyclovir, Acyclovir placebo
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
Not listed
Enrollment
3,682 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
3
States / cities
San Francisco, California • New York, New York • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 30, 2010 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Phase 3 Interventional

Behavioral Drug and HIV Risk Reduction Counseling in Methadone Patients in China

NCT00757744
View directory record Official record
Conditions
Opiate Dependence, HIV Infections
Interventions
Behavioral Drug and HIV Risk Reduction Counseling (BDRC), Drug counseling
Behavioral
Lead sponsor
Yale University
Other
Eligibility
20 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Oct 20, 2026, 11:45 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Behavioral Activation and Risk Reduction for Stimulant Use Among Sexually Active Adolescents and Young Adults

NCT06444360
View directory record Official record
Conditions
HIV
Interventions
IMPACT, eSOC
Behavioral
Lead sponsor
Westat
Other
Eligibility
16 Years to 24 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
2
States / cities
Los Angeles, California • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 20, 2026, 11:45 PM EDT
Recruiting Not applicable Interventional

Families With Pride ("Familias Con Orgullo").

NCT06057337
View directory record Official record
Conditions
Depression, Drug Use
Interventions
Families with Pride ("Familias con Orgullo")
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
13 Years to 19 Years
Enrollment
306 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Project Power: An HIV Risk Reduction Intervention for Black Men Who Have Sex With Men and Women (BMSM/W)

NCT01376895
View directory record Official record
Conditions
Unsafe Sex, Risk Reduction
Interventions
PROJECT POWER, Power Health
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 11, 2014 · Synced Oct 20, 2026, 11:45 PM EDT
Withdrawn Phase 2 Interventional

HIV Risk Reduction and Drug Abuse Treatment in Iran

NCT00398008
View directory record Official record
Conditions
Opiate Dependence, HIV Infections
Interventions
Buprenorphine/Subutex, Naltrexone, Drug counseling
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Phase 1 Interventional

HIV Prevention in Very High Risk Men Who Have Sex With Men

NCT01291589
View directory record Official record
Conditions
Risk Reduction Behavior
Interventions
Cognitive-behavioral therapy
Behavioral
Lead sponsor
Fenway Community Health
Other
Eligibility
18 Years and older · Male only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 9, 2016 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional Results available

Intensity-Modulated Radiation Therapy With or Without Decreased Radiation Dose to Erectile Tissue in Treating Patients With Stage II Prostate Cancer

NCT00084552
View directory record Official record
Conditions
Prostate Cancer, Sexual Dysfunction, Sexuality and Reproductive Issues
Interventions
radiation therapy
Radiation
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
18 Years and older · Male only
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 25, 2021 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional Results available

The SOLVE-IT National Randomized Trial

NCT00653991
View directory record Official record
Conditions
HIV Infections
Interventions
SOLVE-IT
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 24 Years · Male only
Enrollment
2,020 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2019 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computerized Brief Alcohol Intervention (BI) for Binge Drinking HIV At-Risk and Infected Women

NCT01125371
View directory record Official record
Conditions
Alcohol; Harmful Use, Binge Drinking, Risk Behavior, HIV Infection
Interventions
Computerized brief alcohol intervention + IVR booster calls, Computerized brief alcohol intervention, Attention Control
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
439 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 24, 2022 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional

Brief HIV Prevention Counseling for STI Patients in South Africa

NCT01242501
View directory record Official record
Conditions
Sexually Transmitted Infections
Interventions
60 Minute HIV/STI risk reduction counseling.Single 60 min Social Cognitive Theory-based counseling., 20-Min education session
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
1,050 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 11, 2021 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Phase 2 Interventional

Brief Introductory Therapy for Opioid Dependence

NCT00406484
View directory record Official record
Conditions
Opiate Dependence, HIV Infections
Interventions
Standard drug counseling, BDRC
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Parent-Based Intervention to Reduce Sexual Risk Behavior in Adolescents

NCT00461487
View directory record Official record
Conditions
Behavior and Behavior Mechanisms
Interventions
Active control on hygiene and nutrition, Families Talking Together
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
11 Years to 14 Years
Enrollment
530 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 11, 2013 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Proyecto SOL: A Risk Reduction Intervention for Hispanic Men Who Have Sex With Men (MSM)

NCT00690976
View directory record Official record
Conditions
HIV Infections
Interventions
Proyecto SOL, HCT
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years to 49 Years · Male only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Mar 11, 2010 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrated BA and HIV RR Counseling for MSM With Stimulant Abuse

NCT03175159
View directory record Official record
Conditions
Stimulant Abuse, HIV Prevention, Substance Abuse
Interventions
IMPACT, Standard of Care
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Male only
Enrollment
205 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
2
States / cities
Miami, Florida • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 25, 2024 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

DOT Diary Optimization Pilot: A Pilot Study to Optimize the DOT Diary App to Measure PrEP Adherence

NCT03387462
View directory record Official record
Conditions
Adherence, Medication, Risk Behavior, Pre-Exposure Prophylaxis, HIV Prevention
Interventions
Emtricitabine / Tenofovir Disoproxil Oral Tablet, DOT Diary mobile app
Drug · Other
Lead sponsor
Public Health Foundation Enterprises, Inc.
Other
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
San Francisco, California • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 27, 2021 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HIV Risk Reduction in Youth in the Bahamas

NCT00774592
View directory record Official record
Conditions
HIV Infections
Interventions
FOYC, Goal for it (GFI), Wonderous Wetlands, Caribbean Informed Parents and Children Together (CImPACT), Bahamian Focus on Older Youth (BFOOY), Health and Family Life Curriculum (HFLE)
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
Not listed
Enrollment
1,360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2016
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 6, 2017 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional Results available

Cardiovascular Prevention for Persons With HIV

NCT00982189
View directory record Official record
Conditions
HIV Infection, Cardiovascular Disease Risk
Interventions
Pravastatin, Lisinopril
Drug
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
40 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 22, 2017 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional

Reducing Obesity Health Disparities in Hispanic Youth

NCT03943628
View directory record Official record
Conditions
Overweight, Family Relations, Adolescent Behavior, Drug Use, Sexual Behavior
Interventions
Familias Unidas
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 15 Years
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 12, 2022 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Females of African American Legacy Empowering Self (FemAALES)

NCT02189876
View directory record Official record
Conditions
HIV
Interventions
Standard of Care, FemAALES
Behavioral
Lead sponsor
Charles Drew University of Medicine and Science
Other
Eligibility
18 Years to 54 Years · Female only
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2018 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Phase 2 Interventional

Risk Reduction for Urban Substance Using Men Who Have Sex With Men (MSM)

NCT01327898
View directory record Official record
Conditions
HIV Infection, Substance Abuse
Interventions
empowerment theory-based small group discussion, individual resilience counseling
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
515 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
2
States / cities
Miami Beach, Florida • Wilton Manors, Florida
Source: ClinicalTrials.gov public record
Updated Jul 25, 2014 · Synced Oct 20, 2026, 11:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HOME Study: a Combination Support Package to Increase Uptake of PrEP and HIV/STI Testing

NCT03138135
View directory record Official record
Conditions
HIV Prevention, Sexually Transmitted Diseases, Pre-Exposure Prophylaxis
Interventions
HOME Study intervention, Control
Behavioral
Lead sponsor
Public Health Foundation Enterprises, Inc.
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 9, 2021 · Synced Oct 20, 2026, 11:45 PM EDT