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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Sexual Risk Reduction Clear all
Completed Phase 2 Interventional Accepts healthy volunteers

HIV Prevention With the Mentally Ill

NCT00643305
View directory record Official record
Conditions
HIV Infections
Interventions
Skills Building with Motivational Interviewing, Skills Building
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
19 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2013 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Phase 2 Interventional

Effectiveness of Structured Ecosystems Therapy for Reducing HIV Risk Behaviors and Improving Treatment Adherence in HIV Infected Men Released From Prison

NCT00344591
View directory record Official record
Conditions
HIV Infections, Acquired Immunodeficiency Syndrome
Interventions
Structured Ecosystems Therapy (SET), Individually tailored intervention
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2015 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of a Web-based Sexual Violence Risk Reduction Program for Female College Students

NCT03726437
View directory record Official record
Conditions
Sexual Violence
Interventions
RealConsent, Stress and Mood Management
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
18 Years to 20 Years · Female only
Enrollment
881 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Mechanisms of Immune Reconstitution & Reduced Immune Activation Following Darunavir-based ART

NCT01869634
View directory record Official record
Conditions
Human Immunodeficiency Virus Infection
Interventions
darunavir with ritonavir and fixed-dose viread+emtricitabine daily
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
21 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Jul 22, 2026, 5:07 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Game Plan: Efficacy of a Brief, Web-based Intervention on Alcohol Use and Sexually-transmitted Infections

NCT04552171
View directory record Official record
Conditions
Sexually Transmitted Diseases, Bacterial, Alcohol; Harmful Use
Interventions
Access to Game Plan app and 24-hour helpline
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional

Alcohol And Sexual Risk Behavior

NCT04416711
View directory record Official record
Conditions
Sexually Aggressive Behavior, Risky Sexual Behavior, Heavy Episodic Drinking
Interventions
Personalized Feedback, Cognitive Skills Training, Services As Usual
Behavioral · Other
Lead sponsor
Arizona State University
Other
Eligibility
18 Years to 19 Years · Male only
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
2
States / cities
Tempe, Arizona • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

All About Youth: Evaluation of Sexual Risk Avoidance and Risk Reduction Programs for Middle School Students

NCT00167505
View directory record Official record
Conditions
Sexually Transmitted Diseases, Pregnancy, HIV Infections
Interventions
Risk Avoidance Intervention, Risk Reduction Intervention
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
11 Years to 16 Years
Enrollment
1,742 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2010 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Personalized Prevention for Couples: A 16-month Digital RCT

NCT05708014
View directory record Official record
Conditions
Hiv, HIV Infections, Sexually Transmitted Infection, Sexually Transmitted Diseases, Sexual Behavior, Risk Reduction
Interventions
Intervention LuvHub, Waitlist Control LuvHub
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older · Male only
Enrollment
778 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computerized Brief Alcohol Intervention (BI) for Binge Drinking HIV At-Risk and Infected Women

NCT01125371
View directory record Official record
Conditions
Alcohol; Harmful Use, Binge Drinking, Risk Behavior, HIV Infection
Interventions
Computerized brief alcohol intervention + IVR booster calls, Computerized brief alcohol intervention, Attention Control
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
439 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 23, 2022 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Group Prenatal Care for Reducing the Risk of STDs in Pregnant Young Women

NCT00271960
View directory record Official record
Conditions
Sexually Transmitted Diseases, HIV Infections
Interventions
CenteringPregnancy, CenteringPregnancyPlus, Usual care
Behavioral
Lead sponsor
Yale University
Other
Eligibility
14 Years to 25 Years · Female only
Enrollment
1,047 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2008
U.S. locations
2
States / cities
New Haven, Connecticut • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Mobile-Based Application "MyChoices"

NCT03179319
View directory record Official record
Conditions
HIV, Sexually Transmitted Diseases, Pre-exposure Prophylaxis, Risk Reduction
Interventions
MyChoices
Behavioral
Lead sponsor
Fenway Community Health
Other
Eligibility
15 Years to 24 Years · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
Boston, Massachusetts • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Dec 15, 2020 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

An HIV Intervention for Black Men at Risk - The Enhanced Sexual Health Intervention for Men (ES-HIM)

NCT01641146
View directory record Official record
Conditions
HIV, Depression, Posttraumatic Stress Disorder
Interventions
Enhanced Sexual Health Intervention for Men (ES-HIM), Health Promotion (HP) Comparison Arm
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Male only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
4
States / cities
Inglewood, California • Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2016 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Network Intervention for Reducing Sexual Risk for HIV With African American Men Who Have Sex With Men (AA MSM)

NCT00691041
View directory record Official record
Conditions
HIV Infections
Interventions
Unity in Diversity
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years and older · Male only
Enrollment
233 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 12, 2012 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional Results available

The SOLVE-IT National Randomized Trial

NCT00653991
View directory record Official record
Conditions
HIV Infections
Interventions
SOLVE-IT
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 24 Years · Male only
Enrollment
2,020 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reducing Health Problems Associated With Injection Drug Use

NCT01128920
View directory record Official record
Conditions
Intravenous Drug Abuse, HIV Infections
Interventions
Skin and Needle Hygiene Intervention, No intervention - assessment-only condition
Behavioral · Other
Lead sponsor
University of Northern Colorado
Other
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 3, 2012 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Providing Suboxone and PrEP Using Telemedicine

NCT04521920
View directory record Official record
Conditions
Opioid Use, Opioid-use Disorder, Risk Reduction, Hiv
Interventions
Suboxone, PrEP
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
3
States / cities
Charlotte, North Carolina • Durham, North Carolina • Wilmington, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adaptation and Implementation of Project Encuentro in the U.S.-Mexico Border

NCT03293875
View directory record Official record
Conditions
HIV
Interventions
Community Events, Social Network HIV Testing, Peer Network Intervention
Behavioral
Lead sponsor
City University of New York
Other
Eligibility
18 Years and older
Enrollment
840 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional Results available

Understanding and Reducing HIV Risk Behavior and Substance Use Among Self-identified Bisexual Adolescent Men

NCT03409328
View directory record Official record
Conditions
HIV/AIDS, Substance Use, Bisexuality
Interventions
HIV and substance use prevention
Behavioral
Lead sponsor
Rosalind Franklin University of Medicine and Science
Other
Eligibility
14 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
North Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Project Power: An HIV Risk Reduction Intervention for Black Men Who Have Sex With Men and Women (BMSM/W)

NCT01376895
View directory record Official record
Conditions
Unsafe Sex, Risk Reduction
Interventions
PROJECT POWER, Power Health
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional

HIV/STI Risk Reduction for Incarcerated Women With Interpersonal Violence

NCT01907126
View directory record Official record
Conditions
Unsafe Sex, Physical Violence, Sexual Assault, Sexual Abuse
Interventions
Nutrition Program (NP), Women's Prison CoOp (WPC)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
3
States / cities
Framingham, Massachusetts • Cranston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Jul 22, 2026, 5:07 PM EDT
Not listed Phase 2 Interventional

The Aim of This Study is to Determine the Effectiveness of a Motivational Enhancement Intervention in Reducing Risk Behaviors (Drug and Alcohol Use, Sexual Risk Behavior, Poor Adherence to Medications) Among HIV+ Youth. - 1

NCT00227825
View directory record Official record
Conditions
Adherence, HIV Risk Behaviors, Alcohol & Drug Use, Health Behaviors, Sexual Risk Behaviors
Interventions
Motivational interviewing
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
16 Years to 24 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Jul 22, 2026, 5:07 PM EDT
Completed No phase listed Observational

Age-17 Follow-up of Home Visiting Intervention

NCT00708695
View directory record Official record
Conditions
Antisocial Behavior, Psychopathology, Substance Use, HIV Infections
Interventions
Nurse Home Visiting
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
17 Years to 65 Years
Enrollment
1,880 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional

Brief HIV Prevention Counseling for STI Patients in South Africa

NCT01242501
View directory record Official record
Conditions
Sexually Transmitted Infections
Interventions
60 Minute HIV/STI risk reduction counseling.Single 60 min Social Cognitive Theory-based counseling., 20-Min education session
Behavioral
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years and older
Enrollment
1,050 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Jul 22, 2026, 5:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project POWER, Adapting Project SAFE: Reducing STD/HIV Risk in Women Prisoners

NCT01111721
View directory record Official record
Conditions
HIV Infections
Interventions
Project POWER HIV Risk-reduction Intervention, NC DOC Standard of Care for STIs
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
598 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
2
States / cities
Raleigh, North Carolina • Rocky Mount, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 13, 2013 · Synced Jul 22, 2026, 5:07 PM EDT