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ClinicalTrials.gov public records Last synced May 21, 2026, 11:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 241 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Shortness of Breath/Dyspnea Clear all
Completed Phase 2Phase 3 Interventional
View directory record Official record
Conditions
Sarcoidosis, Pulmonary Hypertension
Interventions
Ambrisentan
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 99 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 1, 2018 · Synced May 21, 2026, 11:51 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 28, 2022 · Synced May 21, 2026, 11:51 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Dyspnea
Interventions
Shortness of breath recognition and treatment
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Livonia, Michigan
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced May 21, 2026, 11:51 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Chronic Pulmonary Disorder
Interventions
breathing techniques, Self-Administered Baseline and Transition Dyspnea Indexes
Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
19 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2018 · Synced May 21, 2026, 11:51 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Dyspnea
Interventions
Socialization phase, Speech breathing intervention
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
50 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced May 21, 2026, 11:51 PM EDT
Terminated No phase listed Observational
View directory record Official record
Conditions
Multiple Myeloma, Shortness of Breath, Dyspnea, Cardiotoxicity
Interventions
EndoPAT, Blood Pressure Cuff, Echocardiogram, Quality of Life Assessment, Blood Tests
Device · Diagnostic Test · Other
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced May 21, 2026, 11:51 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
naloxone, normal saline
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
50 Years to 90 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Apr 10, 2013 · Synced May 21, 2026, 11:51 PM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Cancer
Interventions
High-flow Oxygen, Low-flow Oxygen, High-flow Air, Low-flow Air
Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2023 · Synced May 21, 2026, 11:51 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Respiratory Distress, Acute Lung Injury
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 23, 2015 · Synced May 21, 2026, 11:51 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Lung Neoplasm
Interventions
Tele-rehabilitation, Education only
Behavioral · Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 12, 2023 · Synced May 21, 2026, 11:51 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Heart Diseases
Interventions
Not listed
Lead sponsor
PC-HEART
Other
Eligibility
18 Years and older
Enrollment
349 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
14
States / cities
San Diego, California • Washington D.C., District of Columbia • Palm Beach, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Jun 10, 2008 · Synced May 21, 2026, 11:51 PM EDT
Not yet recruiting Not applicable Interventional
View directory record Official record
Conditions
Breast Cancer
Interventions
Respiratory muscle strength training, Guided Imagery Exercises
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 100 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced May 21, 2026, 11:51 PM EDT
Completed No phase listed Observational Results available
View directory record Official record
Conditions
Shortness of Breath Episode, Tachycardia, Bradycardia, Difficulty Breathing
Interventions
Not listed
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
673 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Birmingham, Alabama • Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated May 12, 2024 · Synced May 21, 2026, 11:51 PM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Respiratory Distress, Lung Injury
Interventions
Heated Humidified High Flow Nasal Cannula, Nasal Continuous Positive Airway Pressure
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
2 Hours to 72 Hours
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 14, 2015 · Synced May 21, 2026, 11:51 PM EDT
Enrolling by invitation Not applicable Interventional
View directory record Official record
Conditions
Lung Disease, Lung Ultrasound
Interventions
Lung ultrasound
Device
Lead sponsor
GE Healthcare
Industry
Eligibility
22 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
3
States / cities
New Haven, Connecticut • Chicago, Illinois • Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced May 21, 2026, 11:51 PM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Pulmonary Complication, Dyspnea, Pneumonia, COPD, CHF, Atelectasis, PE
Interventions
Incentive Spirometry
Behavioral
Lead sponsor
Jewish Hospital, Cincinnati, Ohio
Other
Eligibility
65 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced May 21, 2026, 11:51 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Pneumonia, Pulmonary Edema, Dyspnea
Interventions
Lung ultrasound, ultrasound
Procedure · Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 22, 2020 · Synced May 21, 2026, 11:51 PM EDT
Terminated Early Phase 1 Interventional Results available
View directory record Official record
Conditions
Tachycardia, Dyspnea, COVID-19
Interventions
Metoprolol Succinate
Drug
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
18 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced May 21, 2026, 11:51 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Arthritis, Pain
Interventions
Not listed
Lead sponsor
Angela N Fellner PhD CCRP
Other
Eligibility
18 Years to 99 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 21, 2018 · Synced May 21, 2026, 11:51 PM EDT
Completed Not applicable Interventional Results available
View directory record Official record
Conditions
Congestive Heart Failure, Cardiomyopathy, Dyspnea, Pulmonary Edema, Heart Diseases
Interventions
Fluid Status Monitoring (OptiVol™)
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
12
States / cities
Anchorage, Alaska • Atlantis, Florida • Fort Wayne, Indiana + 9 more
Source: ClinicalTrials.gov public record
Updated Oct 12, 2010 · Synced May 21, 2026, 11:51 PM EDT
Terminated Not applicable Interventional
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
Sleep study-guided adjustment of NIV, Standard initiation of NIV
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced May 21, 2026, 11:51 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
COPD, Stress, Dyspnea
Interventions
REST, Education
Behavioral · Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
40 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced May 21, 2026, 11:51 PM EDT
Active, not recruiting Phase 3 Interventional
View directory record Official record
Conditions
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Interventions
Fentanyl Citrate Buccal Tablet, Morphine, Physical Performance Testing, Placebo Administration, Quality-of-Life Assessment, Questionnaire Administration
Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced May 21, 2026, 11:51 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Respiratory Distress, Transient Tachypnea of the Newborn, Delayed Transition of the Newborn, Persistent Pulmonary Hypertension
Interventions
prone positioning, Supine
Procedure
Lead sponsor
Montefiore Medical Center
Other
Eligibility
Female only
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced May 21, 2026, 11:51 PM EDT