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Showing 1–24 of 279 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Shoulder Pain Clear all
Active, not recruiting No phase listed Observational

Shoulder RFA Pilot Study

NCT06039345
View directory record Official record
Conditions
Shoulder Pain, Rotator Cuff Injuries
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
50 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Farmington, Utah • Salt Lake City, Utah • South Jordan, Utah
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jul 23, 2026, 4:18 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Tranexamic Acid (TXA) Administered Prior to Shoulder Arthroscopy on Postoperative Pain Medication Usage: A Randomized Controlled Trial

NCT06920264
View directory record Official record
Conditions
This Study Will Evaluate Whether TXA Reduces Pain
Interventions
Tranexamic acid, placebo
Drug · Other
Lead sponsor
St. Louis Joint Replacement Institute
Other
Eligibility
Not listed
Enrollment
165 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Bridgeton, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Jul 23, 2026, 4:18 PM EDT
Completed Phase 4 Interventional

"MILNACIPRAN" in Subjects With Chronic Shoulder Pain

NCT01289236
View directory record Official record
Conditions
Chronic Shoulder Pain
Interventions
Milnacipran, Placebo
Drug
Lead sponsor
Valera Bussell
Industry
Eligibility
25 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Delray Beach, Florida
Source: ClinicalTrials.gov public record
Updated Aug 8, 2012 · Synced Jul 23, 2026, 4:18 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Examining the Effectiveness of a Connective Tissue Matrix Implant in Reducing Post-operative Pain and Narcotic After Outpatient Arthroscopic Shoulder Surgery

NCT04633837
View directory record Official record
Conditions
Arthroscopic Shoulder Surgery, Pain, Postoperative
Interventions
Extracellular Matrix Graft Injectable Implant
Device
Lead sponsor
Brian Badman
Other
Eligibility
18 Years to 55 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Avon, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 5, 2022 · Synced Jul 23, 2026, 4:18 PM EDT
Withdrawn Phase 4 Interventional

Sphenopalatine Ganglion Block to Prevent Shoulder Pain After Laparoscopic Bariatric Surgery

NCT02809755
View directory record Official record
Conditions
Obesity
Interventions
4% Lidocaine, Saline
Drug · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Jul 23, 2026, 4:18 PM EDT
Completed Not applicable Interventional

The Effectiveness of Self-thoracic Spine Mobilization on Improving Sleep Quality in Patients Who Have Shoulder Pain

NCT03088085
View directory record Official record
Conditions
Shoulder Pain Chronic
Interventions
Self-mobilization, Sleep Education
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Jul 23, 2026, 4:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dry Needling and Shoulder Muscle Blood Flow, Motions, and Pain Sensitivity

NCT05467098
View directory record Official record
Conditions
Dry Needling, Shoulder Pain
Interventions
Dry Needling
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Jul 23, 2026, 4:18 PM EDT
Withdrawn Not applicable Interventional

TrueRelief Efficacy for Supraspinatus Tendonitis

NCT05184985
View directory record Official record
Conditions
Supraspinatus Tendinitis, Shoulder Pain
Interventions
TrueRelief device, Sham TrueRelief device
Device
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 2, 2023 · Synced Jul 23, 2026, 4:18 PM EDT
Completed Phase 4 Interventional

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE.

NCT06109415
View directory record Official record
Conditions
Postoperative Pain, Total Shoulder Arthroplasty, Multimodal Analgesia
Interventions
HTX-011, Bupivacaine Hydrochloride, Ibuprofen, Acetaminophen, Luer lock applicator
Drug · Device
Lead sponsor
Heron Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
5
States / cities
Little Rock, Arkansas • Jenks, Oklahoma • Bellaire, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2023 · Synced Jul 23, 2026, 4:18 PM EDT
Withdrawn Not applicable Interventional

Anatomic Versus Reverse Shoulder Arthroplasty for Primary Glenohumeral Osteoarthritis

NCT06513559
View directory record Official record
Conditions
Glenohumeral Osteoarthritis
Interventions
Anatomic total shoulder replacement, Reverse total shoulder replacement
Device
Lead sponsor
University of Utah
Other
Eligibility
60 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Jul 23, 2026, 4:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dry Needling vs Dry Needling With ES in Patients With Neck/Shoulder Pain

NCT03638388
View directory record Official record
Conditions
Myofascial Pain, Neck Pain, Shoulder Pain
Interventions
Dry needling (DN), Dry needling with intramuscular electrical stimulation (DNES)
Procedure
Lead sponsor
Kindyle Brennan
Other
Eligibility
18 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Belton, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2019 · Synced Jul 23, 2026, 4:18 PM EDT
Not listed Phase 1Phase 2 Interventional

Embolization for the Treatment of Pain Secondary to Adhesive Capsulitis

NCT03676829
View directory record Official record
Conditions
Frozen Shoulder, Adhesive Capsulitis
Interventions
Arterial Embolization of the Shoulder
Device
Lead sponsor
Vascular Institute of Virginia
Other
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Woodbridge, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 20, 2018 · Synced Jul 23, 2026, 4:18 PM EDT
Completed Phase 4 Interventional Results available

Exparel for Postoperative Pain Management in Shoulder Surgery

NCT02472314
View directory record Official record
Conditions
Fracture of Shoulder and Upper Arm
Interventions
1.3% Liposomal Bupivacaine, 0.125% Bupivacaine
Drug
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Dearborn, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 28, 2023 · Synced Jul 23, 2026, 4:18 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow

NCT00634608
View directory record Official record
Conditions
Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy, Bursitis, Depression, Anxiety, Diabetes Mellitus, Esophageal Reflux, HIV Infections, Hyperlipidemia, Hypertension, Insomnia, Irritable Bowel Syndrome, Obesity, Osteoporosis (Senile), Shoulder Pain, Sinusitis, Symptomatic Menopause, Urinary Incontinence, Urinary Tract Infection, Vaginitis
Interventions
Health Information Prescription
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 29, 2016 · Synced Jul 23, 2026, 4:18 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Optimal Effective Local Anesthetic Volume for Pain Relief Using Brachial Plexus Block

NCT05868993
View directory record Official record
Conditions
Post Operative Pain
Interventions
Dose of 0.5% Ropivacaine
Drug
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Jul 23, 2026, 4:18 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Biomechanics of Wheelchair Transfers

NCT00645567
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Unassisted Manual Transfer, Standard Transfer Board, Glide n' Go, Easy Reach lift, Ryno lift
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Jul 23, 2026, 4:18 PM EDT
Not listed Phase 2 Interventional

Pain Patch Versus Injections in the Treatment of Pain Associated With Shoulder Impingement Syndrome

NCT01544283
View directory record Official record
Conditions
Shoulder Pain
Interventions
Synera® (lidocaine 70 mg and tetracaine 70 mg) topical patch, Triamcinolone Acetonide
Drug
Lead sponsor
Injury Care Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Mar 5, 2012 · Synced Jul 23, 2026, 4:18 PM EDT
Enrolling by invitation Phase 4 Interventional

The Effect of Liposomal Bupivacaine Nerve Block (Exparel) in Rotator Cuff Surgery

NCT06139666
View directory record Official record
Conditions
Rotator Cuff Tears, Postoperative Pain, Opioid Use
Interventions
Exparel Injectable Solution, Bupivacaine Injectable Solution
Drug
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Jul 23, 2026, 4:18 PM EDT
Completed No phase listed Observational

Functional and Radiographic Outcomes After Shoulder Surgery

NCT01405781
View directory record Official record
Conditions
Shoulder Pain, Osteoarthritis of Glenohumeral Joint, Rotator Cuff Tear Arthropathy
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
1,034 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2024
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Jul 23, 2026, 4:18 PM EDT
Completed Not applicable Interventional

The Influence of a Cognitive Behavioral Approach on Changing Patient Expectations in Shoulder Pain

NCT03353272
View directory record Official record
Conditions
Rotator Cuff Impingement Syndrome, Rotator Cuff Injury, Shoulder Pain
Interventions
Patient Engagement Education and Restructuring of Cognitions
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 70 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 20, 2024 · Synced Jul 23, 2026, 4:18 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

SPR PNS for Chronic Shoulder Pain

NCT05649917
View directory record Official record
Conditions
Shoulder Pain, Shoulder Injuries, Shoulder Arthritis
Interventions
Not listed
Lead sponsor
International Spine, Pain and Performance Center
Other
Eligibility
21 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Jul 23, 2026, 4:18 PM EDT
Completed Not applicable Interventional Results available

Effects of Myofascial Massage and Patient-therapist Communication Levels on Shoulder Muscle Properties in Breast Cancer Survivors With Myofascial Pain

NCT06679400
View directory record Official record
Conditions
Pain, Myofacial
Interventions
Massage
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jul 23, 2026, 4:18 PM EDT
Completed Not applicable Interventional Results available

Multimodal Treatment for Hemiplegic Shoulder Pain

NCT02893267
View directory record Official record
Conditions
Stroke, Shoulder Pain
Interventions
Peripheral Nerve Stimulation, Physical Therapy, Sham-PT, Sham-PNS
Device · Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
21 Years to 89 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
3
States / cities
Chicago, Illinois • Charlotte, North Carolina • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Jul 23, 2026, 4:18 PM EDT
Terminated Phase 4 Interventional

Pain Management After Total Shoulder Arthroplasty

NCT03219983
View directory record Official record
Conditions
Glenohumeral Arthritis, Total Shoulder Arthroplasty
Interventions
Ropivacaine, liposomal bupivacaine
Drug
Lead sponsor
The Christ Hospital
Other
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 5, 2017 · Synced Jul 23, 2026, 4:18 PM EDT