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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Shoulder Pain Clear all
Recruiting No phase listed Observational

Evaluating Hemidiaphragmatic Paralysis With Prolonged Neural Blockade From an Interscalene Brachial Plexus Block

NCT04209504
View directory record Official record
Conditions
Shoulder Surgery, Shoulder Pain, Shoulder Injuries, Shoulder Arthritis, Shoulder Disease, Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Arthropathy of Left Shoulder, Rotator Cuff Arthropathy of Right Shoulder, Rotator Cuff Repair
Interventions
Ultrasound, Ropivacaine, Bupivacaine, MediPines AGM100 Advanced Respiratory Monitoring System
Diagnostic Test · Drug · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 30, 2025 · Synced Sep 22, 2026, 9:56 AM EDT
Not listed Phase 2 Interventional

Pain Patch Versus Injections in the Treatment of Pain Associated With Shoulder Impingement Syndrome

NCT01544283
View directory record Official record
Conditions
Shoulder Pain
Interventions
Synera® (lidocaine 70 mg and tetracaine 70 mg) topical patch, Triamcinolone Acetonide
Drug
Lead sponsor
Injury Care Medical Center
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Mar 5, 2012 · Synced Sep 22, 2026, 9:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Using Kinect Motion Capture to Measure Shoulder Motion in Patients Undergoing Capsular Distension for Adhesive Capsulitis

NCT04413162
View directory record Official record
Conditions
Adhesive Capsulitis, Adhesive Capsulitis of Shoulder, Frozen Shoulder, Shoulder Frozen, Shoulder Pain, Mobility Limitation
Interventions
Kinect motion tracking system
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Sep 22, 2026, 9:56 AM EDT
Completed Not applicable Interventional

Evaluation of Supraclavicular, Suprascapular, and Interscalene Nerve Blocks for Outpatient Shoulder Surgery

NCT02287142
View directory record Official record
Conditions
Pain, Postoperative, Pain, Shoulder Joint, Pathologic Processes
Interventions
Brachial plexus nerve block
Procedure
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years and older
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Sep 22, 2026, 9:56 AM EDT
Terminated Phase 4 Interventional Results available

Superficial Cervical Plexus Block for Shoulder Pain After Lung Surgery

NCT01550302
View directory record Official record
Conditions
Shoulder Pain
Interventions
Superficial Cervical Plexus Block, Bupivacaine
Procedure · Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 17, 2017 · Synced Sep 22, 2026, 9:56 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of a Model of Shoulder Pain Following Spinal Cord Injury

NCT03137394
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Observation
Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
2
States / cities
Gwynn Oak, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Sep 22, 2026, 9:56 AM EDT
Not yet recruiting Not applicable Interventional

Pneumoperitoneum Management With SurgiQuest AirSeal® at Low vs. Higher Pressure

NCT02837601
View directory record Official record
Conditions
Shoulder Pain
Interventions
AirSeal® Insufflation System (AIS)
Device
Lead sponsor
Akron Children's Hospital
Other
Eligibility
Up to 21 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 12, 2020 · Synced Sep 22, 2026, 9:56 AM EDT
Withdrawn Phase 4 Interventional

Improving Pain Management After Total Shoulder Replacement Using Bupivacaine Liposome

NCT04134442
View directory record Official record
Conditions
Osteoarthritis of the Shoulder, Shoulder Pain, Pain, Postoperative
Interventions
Bupivacaine Liposome Injection, Standard Therapy
Drug · Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 5, 2022 · Synced Sep 22, 2026, 9:56 AM EDT
Completed Phase 4 Interventional Results available

Neuromuscular Blockade on Shoulder Pain of Elderly

NCT03210376
View directory record Official record
Conditions
Malignant Neoplasms of Digestive Organs, Malignant Neoplasms of Female Genital Organs, Malignant Neoplasms of Male Genital Organs, Malignant Neoplasms of Urinary Tract
Interventions
Deep Neuromuscular Blockade (NMB), Moderate Neuromuscular Blockade (NMB), Sugammadex, Neostigmine, Pain Assessment
Drug · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
65 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 24, 2020 · Synced Sep 22, 2026, 9:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physical Therapy Program for Prevention of Shoulder Pain After Device Implant

NCT00680537
View directory record Official record
Conditions
Shoulder Pain
Interventions
Exercises
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Sep 22, 2026, 9:56 AM EDT
Enrolling by invitation No phase listed Observational

Reverse Shoulder Arthroplasty vs Rotator Cuff Repair for 60+

NCT06848023
View directory record Official record
Conditions
Shoulder Injuries, Shoulder Pain
Interventions
Reverse Total Shoulder Arthroplasty, Rotator Cuff Repair
Procedure
Lead sponsor
Campbell Clinic
Other
Eligibility
60 Years to 95 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Germantown, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 22, 2026, 9:56 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Hormones, Outcomes, and Pain Pathways in Exercise Study

NCT07579182
View directory record Official record
Conditions
Breast Pain, Mastalgia, Back Pain, Back Pain, Low, Neck Pain, Chest Pain, Activity, Motor, Healthy Aging, Weight, Body, Inflammation, Gonadal Steroid Hormones, Neuronal Plasticity, Neuromuscular Manifestations
Interventions
Interventional Sports bra
Other
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Sep 22, 2026, 9:56 AM EDT
Completed Not applicable Interventional

Type of Exercise and Education in Patients With SubAcromial Pain Syndrome

NCT03127839
View directory record Official record
Conditions
Shoulder Pain
Interventions
Eccentric Strengthening, Traditional Strengthening, Pain education
Procedure · Behavioral
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Sep 22, 2026, 9:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Battlefield Acupuncture and Physical Therapy Versus Physical Therapy Alone After Shoulder Surgery

NCT03525275
View directory record Official record
Conditions
Opioid Use, Pain, Postoperative, SLAP Lesion, Bankart Lesion, Subacromial Impingement Syndrome, Rotator Cuff Tear, Glenohumeral Dislocation, Glenohumeral Subluxation, Hill Sach Lesion, Bony Bankart Lesion, Acromioclavicular Separation
Interventions
Battlefield Acupuncture, Post-surgical shoulder protocol
Device · Procedure
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
17 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated May 19, 2019 · Synced Sep 22, 2026, 9:56 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Pain Increases After Shoulder Injection

NCT05438277
View directory record Official record
Conditions
Shoulder Pain
Interventions
Methylprednisolone (MPA), Triamcinolone Acetonide (TA)
Drug
Lead sponsor
Campbell Clinic
Other
Eligibility
18 Years to 99 Years
Enrollment
421 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Germantown, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Sep 22, 2026, 9:56 AM EDT
Completed Not applicable Interventional

Maintenance of Shoulder Health and Function After Spinal Cord Injury

NCT02135978
View directory record Official record
Conditions
Spinal Cord Injury, Shoulder Pain
Interventions
Shoulder home exercise program
Other
Lead sponsor
Rancho Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Downey, California
Source: ClinicalTrials.gov public record
Updated Apr 10, 2018 · Synced Sep 22, 2026, 9:56 AM EDT
Completed Phase 4 Interventional Results available

Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury.

NCT00320281
View directory record Official record
Conditions
Spinal Cord Injury, Pain
Interventions
botulinum toxin A, placebo
Drug · Other
Lead sponsor
Craig Hospital
Other
Eligibility
15 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Englewood, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Sep 22, 2026, 9:56 AM EDT
Not yet recruiting Not applicable Interventional

The Immediate Effects of First Rib Mobilization on Pain and Range of Motion in Patients With Shoulder Pain

NCT07064772
View directory record Official record
Conditions
Shoulder Pain
Interventions
First Rib Mobilization, Sham Comparator
Other
Lead sponsor
Andrews University
Other
Eligibility
18 Years to 75 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Annville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2025 · Synced Sep 22, 2026, 9:56 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

SPR PNS for Chronic Shoulder Pain

NCT05649917
View directory record Official record
Conditions
Shoulder Pain, Shoulder Injuries, Shoulder Arthritis
Interventions
Not listed
Lead sponsor
International Spine, Pain and Performance Center
Other
Eligibility
21 Years to 100 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
2
States / cities
Washington D.C., District of Columbia • Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 22, 2026, 9:56 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Surgeons Can Avoid Lasting Pain Through Exercise Literacy

NCT05175443
View directory record Official record
Conditions
Neck Pain, Shoulder Pain
Interventions
Exercise
Other
Lead sponsor
Timothy Uhl
Other
Eligibility
18 Years to 99 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 24, 2023 · Synced Sep 22, 2026, 9:56 AM EDT
Not yet recruiting Not applicable Interventional

Laterality Training and Pain Drawings

NCT07078084
View directory record Official record
Conditions
Chronic Musculoskeletal Pain, Chronic Shoulder Pain, Chronic Knee Pain
Interventions
Laterality Training, Sham (No Treatment)
Behavioral · Other
Lead sponsor
Hawaii Pacific University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Moline, Illinois • Davenport, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Sep 22, 2026, 9:56 AM EDT
Completed Not applicable Interventional

Interscalene Bupivacaine With Either Liposomal Bupivacaine or Continuous Peripheral Nerve Block for Shoulder Arthroscopy

NCT03816982
View directory record Official record
Conditions
Shoulder Pain
Interventions
Single-injection bupivacaine HCl plus liposomal bupivacaine, Single-injection bupivacaine HCl plus a subsequent bupivacaine CISB
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 22, 2023 · Synced Sep 22, 2026, 9:56 AM EDT
Enrolling by invitation No phase listed Observational

MDR - Comprehensive Primary Revision Stems PMCF

NCT06788717
View directory record Official record
Conditions
Shoulder Pain, Shoulder Injuries, Shoulder Fractures, Shoulder Disease, Shoulder Arthritis
Interventions
Comprehensive Primary Revision Stems
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years to 100 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2040
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 22, 2026, 9:56 AM EDT
Completed Not applicable Interventional

Prospective RCT Comparing Perioperative Pain

NCT03253198
View directory record Official record
Conditions
Arthroplasty Shoulder
Interventions
Saline, Bupivacaine liposome
Drug
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 21, 2018 · Synced Sep 22, 2026, 9:56 AM EDT