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ClinicalTrials.gov public records Last synced Oct 21, 2026, 3:45 PM EDT

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Showing 1–24 of 132 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Skin Aging Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

Clinical Evaluation of Day and Night Skin Care Creams Supplemented With MediCell Technology (MCT)'s Composition of Defensins and Supportive Molecules

NCT02765763
View directory record Official record
Conditions
Skin Aging, Photoaging of Skin
Interventions
2-Minute Reveal Masque, 24/7 Barrier Repair Cream, 8-in-1 BioSerum, Null Formula 2-Minute Reveal Masque, Null Formula 24/7 Barrier Repair Cream, Null Formula 8-in-1 BioSerum
Drug
Lead sponsor
Advanced Dermatology
Other
Eligibility
40 Years to 75 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lincolnshire, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 11, 2018 · Synced Oct 21, 2026, 3:45 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Evaluate the Efficacy of Activated Silk™ 27P-α in Subjects, Aged 35-65 Years of Age, to Improve the Signs of Aging

NCT06804759
View directory record Official record
Conditions
Skin Aging
Interventions
Investigational Facial Serum #1, Investigational Facial Serum #2, Investigational Facial Serum #3
Other
Lead sponsor
Victoria Collotta
Industry
Eligibility
35 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Needham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Pomegranate on Aging and Inflammation of the Skin

NCT02258776
View directory record Official record
Conditions
Skin Photoaging, Inflammation and Skin Pathogenic Bacteria
Interventions
Pomegranate Extract, Pomegranate Juice, Placebo
Dietary Supplement
Lead sponsor
University of California, Los Angeles
Other
Eligibility
30 Years to 45 Years · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 1, 2017 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Orally Delivered Phytochemicals on Aging and Inflammation in the Skin

NCT03289832
View directory record Official record
Conditions
Healthy Adults
Interventions
Crucera-SGS, Meriva 500-SF
Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dealcoholized Muscadine Wine and Skin Health in Women

NCT04614753
View directory record Official record
Conditions
Skin Health
Interventions
Dealcoholized Muscadine Wine, Control Beverage
Other
Lead sponsor
University of Florida
Other
Eligibility
40 Years to 67 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 21, 2026, 3:45 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Study of Chemotherapy-Induced Hair Changes and Alopecia, Skin Aging and Nail Changes in Women With Non-Metastatic Breast Cancer

NCT02530177
View directory record Official record
Conditions
Non-Metastatic Breast Cancer
Interventions
Clinical Assessments, Questionnaires, Saliva sample
Other · Behavioral
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
546 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Phase 1 Study of the Effects of Combining Topical FDA-approved Drugs on Age-related Pathways on the Skin of Healthy Volunteers

NCT03072485
View directory record Official record
Conditions
Aging
Interventions
Sirolimus, Metformin, Diclofenac
Drug
Lead sponsor
Anne Chang
Other
Eligibility
55 Years and older · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2019 · Synced Oct 21, 2026, 3:45 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluate the Safety and Efficacy of a Topical Serum (AGE Serum) in Improving Visible Signs of Aging

NCT07216352
View directory record Official record
Conditions
Laxity; Skin
Interventions
AGE Serum
Other
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
25 Years to 50 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2025 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Not applicable Interventional

A Proof of Concept Study to Evaluate the Efficacy and Tolerability of Skinpen on Male and Female Subjects' Dorsal Hands as a Treatment of Hand Aging

NCT05030051
View directory record Official record
Conditions
Skin Aging
Interventions
SkinPen Precision System
Device
Lead sponsor
Crown Laboratories, Inc.
Industry
Eligibility
50 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study to Identify if Saie Beauty's Under Eye Concealer Works to Improve Under-Eye Skin Appearance and Reduce Imperfections

NCT05231681
View directory record Official record
Conditions
Wrinkle
Interventions
Saie Beauty's Hydrabeam Sheer Brightening Under Eye Concealer
Dietary Supplement
Lead sponsor
Saie Beauty
Industry
Eligibility
18 Years to 45 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated May 6, 2022 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Skin Safety Profile of Different Exposure to the Light Emitting Diode (LED) in Healthy Subjects

NCT00818311
View directory record Official record
Conditions
Radiation Tolerance, Skin Aging, Rhytids
Interventions
LED GentleWaves®
Device
Lead sponsor
L'Oreal
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Carrollton, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2009 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Evaluate the Effects for Midface Improvement When Pairing a Biostimulator with a Skincare Regimen

NCT05963204
View directory record Official record
Conditions
Photodamaged Skin, Volume Deficiency of the Midface
Interventions
Sculptra and Alastin Restorative Skin Complex, Sculptra and CeraVe Daily Moisturizing Lotion
Combination Product
Lead sponsor
Galderma R&D
Industry
Eligibility
22 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Case Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment on Healthy Females with Fitzpatrick Skin Types V and VI

NCT06633731
View directory record Official record
Conditions
Skin Smoothness, Radiance, Overall Appearance
Interventions
Biocellulose Mask, Post Procedure Cream, Gentle Cleanser, Facial Moisturizer, sunscreen
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
45 Years to 65 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Oct 21, 2026, 3:45 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

The Lake Nona Life Project

NCT02533804
View directory record Official record
Conditions
Health Behavior, Quality of Life, Aging
Interventions
Not listed
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 110 Years
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Dec 6, 2024 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Safety and Tolerability of a Brightening Treatment Paired With a Skincare Regimen

NCT07501000
View directory record Official record
Conditions
Hyperpigmentation, Skin Ageing, Post Inflammatory Hyperpigmentation, Skin Roughness
Interventions
Brightening Treatment
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
20 Years to 65 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 21, 2026, 3:45 PM EDT
Completed No phase listed Observational

Biomarkers in Blood Samples From Older Breast Cancer Survivors

NCT01138345
View directory record Official record
Conditions
Breast Cancer
Interventions
gene expression analysis, reverse transcriptase-polymerase chain reaction, laboratory biomarker analysis, medical chart review, questionnaire administration
Genetic · Other
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
50 Years and older · Female only
Enrollment
246 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 27, 2014 · Synced Oct 21, 2026, 3:45 PM EDT
Recruiting Not applicable Interventional

Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia

NCT03906253
View directory record Official record
Conditions
Actinic Keratoses, Aging, Non-Melanoma Skin Cancer
Interventions
Fractionated Laser Resurfacing
Device
Lead sponsor
Wright State University
Other
Eligibility
60 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 21, 2026, 3:45 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of a Longevity Supplement on Aging and Photoaging

NCT05262036
View directory record Official record
Conditions
Photoaging
Interventions
Anti-aging Supplement, Placebo
Dietary Supplement
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
35 Years to 70 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Oct 21, 2026, 3:45 PM EDT
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Randomized Trial of Combination Treatment With Sofwave and Sculptra

NCT07342452
View directory record Official record
Conditions
Skin Aging
Interventions
Sofwave, Sculptra
Device · Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 3:45 PM EDT
Recruiting No phase listed Observational

A Novel Approach Utilizing Organ Specific Age Proteomics

NCT06789653
View directory record Official record
Conditions
Breast Cancer
Interventions
p16INK4a mRNA level assessment, organ-specific protein signatures assessment
Diagnostic Test
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
22 Years to 66 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 21, 2026, 3:45 PM EDT
Terminated Phase 1 Interventional Accepts healthy volunteers

Explore Effects of Dietary Fish Oil in Human Skin

NCT03122912
View directory record Official record
Conditions
Aging Problems
Interventions
Fish Oil, Soybean Oil
Dietary Supplement
Lead sponsor
University of Michigan
Other
Eligibility
50 Years to 99 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 6, 2021 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Solarplast for Health and Oxidative Stress

NCT04144777
View directory record Official record
Conditions
Oxidative Stress, Healthy Aging, Skin Health
Interventions
Solarplast
Dietary Supplement
Lead sponsor
Deerland Enzymes
Industry
Eligibility
18 Years to 65 Years
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Kennesaw, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 15, 2021 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Trial to Examine the Efficacy of a Hand Serum and Glove Combination.

NCT06521177
View directory record Official record
Conditions
Skin Health, Dermatology, Skin Care
Interventions
Hand Serum and Glove
Other
Lead sponsor
Habelo Beauty
Industry
Eligibility
35 Years and older · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Jul 25, 2024 · Synced Oct 21, 2026, 3:45 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Avocado vs. Usual Diet on Skin Aging

NCT05102604
View directory record Official record
Conditions
Skin Inflammation
Interventions
Avocado, Habitual diet
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
25 Years to 90 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Oct 21, 2026, 3:45 PM EDT