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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Skin Hydration Clear all
Completed Phase 1Phase 2 Interventional

Effects of 2% IDL Lotion on Skin Hydration and Transepidermal Water Loss in Females With Dry Skin

NCT04253704
View directory record Official record
Conditions
Xerosis Cutis
Interventions
IDL lotion, Control lotion
Combination Product
Lead sponsor
Shyla Cantor
Industry
Eligibility
35 Years to 57 Years · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Blauvelt, New York
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Phase 4 Interventional Results available

A Study to Investigate the Use of Hydrogel Vehicle in Maintaining the Skin Barrier in Persons With Atopic Dermatitis

NCT01065714
View directory record Official record
Conditions
Atopic Dermatitis
Interventions
Hydrogel vehicle, Eucerin Lotion
Drug
Lead sponsor
Derm Research, PLLC
Other
Eligibility
12 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of a Dietary Supplement on Parameters of Skin Aging in Men and Women

NCT06083402
View directory record Official record
Conditions
Skin Aging
Interventions
HyaCera™, Placebo
Dietary Supplement
Lead sponsor
Natals, Inc. dba Ritual
Industry
Eligibility
25 Years to 70 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Raritan, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 15, 2023 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Trial to Evaluate the Efficacy of Skin Products to Improve Skin Quality and Health

NCT06853899
View directory record Official record
Conditions
Skin Hydration, Skin Aging
Interventions
Truology A2, Truology C-Boost, Truology Barrier Restore
Dietary Supplement
Lead sponsor
Truology
Industry
Eligibility
35 Years to 55 Years · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Mar 2, 2025 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Natreon Healthy Skin Study - PrimaVie Supplement

NCT02762032
View directory record Official record
Conditions
Healthy
Interventions
PrimaVie Herbal Supplement 125, PrimaVie Herbal Supplement 250, Placebo
Dietary Supplement · Drug
Lead sponsor
Ohio State University
Other
Eligibility
30 Years to 65 Years · Female only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
3
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Jul 22, 2026, 4:44 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Skin Hydration in Persons With Acne After Dietary Supplementation With Botanical Antioxidants

NCT04534140
View directory record Official record
Conditions
Acne Vulgaris, Acne
Interventions
HBKB Capsule, HBKB Supplement Vehicle
Dietary Supplement · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 27, 2021 · Synced Jul 22, 2026, 4:44 AM EDT
Completed No phase listed Observational

Hydration Sensor for Atopic Dermatitis

NCT03813472
View directory record Official record
Conditions
Atopic Dermatitis, Healthy Children
Interventions
Hydration Sensor
Device
Lead sponsor
Northwestern University
Other
Eligibility
Up to 18 Years
Enrollment
172 participants
Timeline
2019 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Not applicable Interventional

A Controlled Clinical Study of 2 Different Moisturizers for the Relief of Dry Skin

NCT04510103
View directory record Official record
Conditions
Skin, Skin Care, Skin Cream
Interventions
Moisturizer A, F#9155-005, Moisturizer B, F#E1387-004, Regression, Non-Regression
Drug · Other · Procedure
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Phase 2 Interventional Results available

Rosacea and Ivermectin

NCT04275999
View directory record Official record
Conditions
Rosacea
Interventions
ivermectin, digital interaction, GPSkin
Drug · Behavioral · Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Skin Hydration in Adults With Dry Skin Using a Moisturizer With an Added Sterilized Probiotic

NCT05013645
View directory record Official record
Conditions
Dry Skin
Interventions
Sterilized probiotic LfQi601, Placebo
Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Jul 22, 2026, 4:44 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Ovolux Beauty From Within Trial#2

NCT07188051
View directory record Official record
Conditions
Skin Sagging, Skin Wrinkling, Skin Dryness
Interventions
Ovolux brand eggshell membrane powder, Placebo
Dietary Supplement
Lead sponsor
ESM Technologies, LLC
Industry
Eligibility
35 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Benefits of FloraGLO™ Lutein on Skin Health

NCT03769779
View directory record Official record
Conditions
Aging, Wrinkle, Skin Elasticity, Healthy, Hydration
Interventions
FloraGLO Lutein, Safflower Oil
Dietary Supplement
Lead sponsor
Kemin Foods LC
Industry
Eligibility
30 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Port Chester, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Study to Evaluate the Impact of aKwa Skincare System on Skin Health

NCT05476406
View directory record Official record
Conditions
Sin Health, Skin Hydration, Skin Wrinkles, Skin Porphyrins, Facial Skin Red Spots, Facial Skin Red Vasculature
Interventions
äKwä skincare system products, competitor products (control)
Other
Lead sponsor
4Life Research, LLC
Industry
Eligibility
18 Years to 55 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Sandy City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Durability of Two Skin Barrier Protectants (SBP)

NCT05756348
View directory record Official record
Conditions
Skin Hydration in Healthy Volunteers
Interventions
Marathon® XL No Sting Cyanoacrylate Skin Protectant and 3M™ Cavilon™ Advanced Skin Protectant
Device
Lead sponsor
Medline Industries
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Northfield, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Jul 22, 2026, 4:44 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of SPM™ Topical Cosmetic Application on Skin Appearance, Hydration, and Barrier Support in Healthy Adults

NCT07236736
View directory record Official record
Conditions
Healthy Skin, Skin Hydration
Interventions
Skin biopsy, Corneometer® Measurement, Tewameter® Measurement
Procedure · Other
Lead sponsor
Biocoz Global Pte. Ltd.
Industry
Eligibility
20 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
West Hollywood, California
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Jul 22, 2026, 4:44 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Skin Hydration and Facial Aging in Women Aged 30-60: An Observational Correlational Study Using Bioimpedance Analysis

NCT07564869
View directory record Official record
Conditions
Skin Aging, Skin Hydration, Facial Aging, Transepidermal Water Loss
Interventions
BT-Analyze Bioimpedance Measurement
Other
Lead sponsor
IAS Skin Care
Industry
Eligibility
30 Years to 60 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Winter Garden, Florida
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Jul 22, 2026, 4:44 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Oral Supplementation of Astaxanthin on Skin Photoaging, Hydration and Elasticity

NCT05882084
View directory record Official record
Conditions
Photoaging
Interventions
Astaxanthin 6 mg daily, Placebo
Dietary Supplement
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
30 Years to 55 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Trial Assessing the Impact on Facial Skin Quality, Hydration, and Skin Barrier of Three (3) Hydrafacial Treatments in Adults of All Skin Types.

NCT05932732
View directory record Official record
Conditions
Cutis Laxa Facialis, Xeroderma
Interventions
HydraFacial Syndeo System, ReGen-GF, HydraFacial Elite MD System
Device · Drug
Lead sponsor
Austin Institute for Clinical Research
Network
Eligibility
30 Years to 55 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Houston, Texas • Pflugerville, Texas
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Phase 4 Interventional

Assess the Ability of MetroGel 1% to Deliver Moisture to Facial Skin After a Single Application

NCT00436527
View directory record Official record
Conditions
Rosacea
Interventions
Metronidazole gel 1%
Drug
Lead sponsor
Galderma R&D
Industry
Eligibility
18 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 28, 2022 · Synced Jul 22, 2026, 4:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eggshell Membrane Beauty From Within Trial

NCT06148337
View directory record Official record
Conditions
Skin Elasticity, Skin Hydration, Skin Barrier to Water Loss, Fingernail Health, Hair Health
Interventions
unhydrolyzed eggshell membrane, Placebo
Dietary Supplement
Lead sponsor
ESM Technologies, LLC
Industry
Eligibility
35 Years to 70 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Jul 22, 2026, 4:44 AM EDT