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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Skin Microbiome Clear all
Recruiting Not applicable Interventional

Probiotics in Adults With Rheumatoid Arthritis

NCT07304505
View directory record Official record
Conditions
Rheumatoid Arthritis (RA)
Interventions
Align Extra Strength Probiotic Supplement
Dietary Supplement
Lead sponsor
Ancilia Biosciences
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Phase 1 Interventional Results available

Melanoma Checkpoint and Gut Microbiome Alteration With Microbiome Intervention

NCT03817125
View directory record Official record
Conditions
Metastatic Melanoma
Interventions
Placebo for antibiotic, Vancomycin pretreatment, Nivolumab, Matching Placebo for SER-401, SER-401
Drug
Lead sponsor
Parker Institute for Cancer Immunotherapy
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
7
States / cities
Los Angeles, California • Boston, Massachusetts • New Brunswick, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Jul 23, 2026, 7:01 AM EDT
Not listed Not applicable Interventional

Assessment of the Effects on the Skin Microbiome of Amending an Over-the-counter Eczema Product With Activated Oil (AO)

NCT05413395
View directory record Official record
Conditions
Eczema
Interventions
topical colloidal oatmeal formulation with a modified plant oil, topical colloidal oatmeal formulation
Other
Lead sponsor
GlycosBio, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 4, 2022 · Synced Jul 23, 2026, 7:01 AM EDT
Active, not recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Lipidome and Microbiome Profile of Acne

NCT02713607
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Doxycycline
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
15 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Observational

Evaluating Mepitel in Post-mastectomy Patients and the Role of the Skin Microbiome in Radiation Dermatitis

NCT03519438
View directory record Official record
Conditions
Breast Cancer
Interventions
Mepitel
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Timeline
2018 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Jul 23, 2026, 7:01 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Studies of Skin Microbes in Healthy People and in People With Skin Conditions

NCT00605878
View directory record Official record
Conditions
Eczema, Atopic Dermatitis
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
2 Years to 100 Years
Enrollment
530 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional

Clinical Trial to Assess the Effects of Topical Lotions on Changes in the Skin Microbiome and Associations With Itch

NCT03673059
View directory record Official record
Conditions
Microbiota
Interventions
OTC Eczema Moisturizer Regimen, Cosmetic Moisturizer Regimen
Drug · Other
Lead sponsor
Johnson & Johnson Consumer Products Company Division of Johnson & Johnson Consumer Companies, Inc.
Industry
Eligibility
16 Years to 50 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Colorado Springs, Colorado • Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2018 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional

Effect of an Antiseptic Solution on the Skin Microbiome

NCT05608382
View directory record Official record
Conditions
Skin Diseases, Infectious
Interventions
sterile Phosphate Buffer Saline, SGW13
Other
Lead sponsor
Center for Innovation and Research Organization
Network
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Jul 23, 2026, 7:01 AM EDT
Enrolling by invitation No phase listed Observational

Pilot Study to Characterize the Microbiome in Cutaneous T Cell Lymphoma Skin Lesions Before and After Use of CLn® Skin Care Body Wash

NCT06665490
View directory record Official record
Conditions
Cutaneous T Cell Lymphoma
Interventions
CLn Body Wash
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 89 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Characterizing Skin Microbiome Change in Atopic Dermatitis

NCT04800185
View directory record Official record
Conditions
Atopic Dermatitis, Atopic Dermatitis Eczema
Interventions
Crisaborole 2% Top Oint, Skin Microbiome Swabs
Drug · Genetic
Lead sponsor
University of California, Irvine
Other
Eligibility
2 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Jul 23, 2026, 7:01 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Oral Probiotics on the Shift in Gut Microbiome and Skin Carotenoid Levels

NCT04841694
View directory record Official record
Conditions
Human Microbiome
Interventions
Probiotic
Dietary Supplement
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
40 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 2, 2021 · Synced Jul 23, 2026, 7:01 AM EDT
Withdrawn Phase 2 Interventional

Evaluation of the Kinetic Properties of an Autologous Microbiome Transplant in Adult Atopic Dermatitis Patients

NCT02144142
View directory record Official record
Conditions
Atopic Dermatitis, Eczema
Interventions
Moisturizer with each subject's own antimicrobial bacteria
Biological
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Oral Probiotics and Herbal Supplementation on the Gut Microbiome and Sebum Excretion Rate in Non-Cystic Acne

NCT05919810
View directory record Official record
Conditions
Acne Vulgaris, Acneiform Eruptions, Skin Diseases, Sebaceous Gland Diseases
Interventions
Probiotic, Oral herbal powder supplement
Other · Dietary Supplement
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
12 Years to 45 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2024 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pediatric Microbiome Study With Children Now Approximately 8-10 Years Old.

NCT03485755
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Not listed
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
8 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Skillman, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 25, 2019 · Synced Jul 23, 2026, 7:01 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Quest to Analyze One Thousand Humans Meditating

NCT06583395
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma, Atrial Fibrillation, Cancer Brain, Cancer, Breast, Cancer Colon, Cancer, Lung, Cancer, Ovarian, Cancer Prostate, Cancer Skin, Throat Cancer, Lymphoma, Cancer, Thyroid, Cancer, Other, Cerebral Palsy, Chronic Fatigue Syndrome, Cluster Headache, Chronic Obstructive Pulmonary Disease (COPD), Chronic Kidney Diseases, Crohn Disease, Deafness, Depression, Diabetes, Eczema, Epilepsy, Fibroids, Fibromyalgia, Heart Failure, Hypertension, Hyperthyroidism, Hypothyroidism, Irritable Bowel Syndrome (IBS), Infertility, Lyme Disease, Macular Degeneration, Migraine, Multiple Allergies, Multiple Sclerosis, Osteoarthritis, Osteoporosis, Ovarian Cysts, Parkinson Disease, Phantom Limb Pain, Psoriasis, Post Traumatic Stress Disorder (PTSD), Rheumatoid Arthritis, Sjogrens Disease, Spinal Cord Injury, Spinal Stenosis, Stroke, Tension Headache, Tinnitus, Ulcerative Colitis
Interventions
Advanced multi-component meditation practice
Behavioral
Lead sponsor
Tobias Moeller-Bertram
Industry
Eligibility
21 Years and older
Enrollment
3,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Palm Desert, California
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Jul 23, 2026, 7:01 AM EDT
Recruiting Not applicable Interventional

TNBC Gut Microbiota During Neoadjuvant Treatment

NCT06610097
View directory record Official record
Conditions
Breast Cancer, Triple Negative Breast Cancer, Early Stage Triple-Negative Breast Carcinoma
Interventions
Nutritional Counseling
Other
Lead sponsor
Scripps Health
Other
Eligibility
18 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 22, 2025 · Synced Jul 23, 2026, 7:01 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.

NCT07544251
View directory record Official record
Conditions
Acne Vulgaris
Interventions
Sarecycline, Doxycycline
Drug
Lead sponsor
Integrative Skin Science and Research
Industry
Eligibility
9 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Active, not recruiting Not applicable Interventional

Gut Microbe Composition, Exercise, and Breast Breast Cancer Survivors

NCT04088708
View directory record Official record
Conditions
Breast Cancer, Gut Microbiome, Exercise, Fatigue
Interventions
Aerobic Exercise Training, Attention Control
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 74 Years · Female only
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Jul 23, 2026, 7:01 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

ARGONAUT: Stool and Blood Sample Bank for Cancer Patients

NCT04638751
View directory record Official record
Conditions
Non-small Cell Lung Cancer, Colorectal Cancer, Triple Negative Breast Cancer, Pancreas Cancer
Interventions
Immunotherapy, Chemotherapy, CRC surgical resection, Colonoscopy
Drug · Procedure
Lead sponsor
Persephone Biosciences
Industry
Eligibility
18 Years and older
Enrollment
5,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
10
States / cities
Orange, California • San Diego, California • Miami, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Nitrosomonas Eutropha on Nitrolipids in the Skin

NCT02938650
View directory record Official record
Conditions
Inflammation
Interventions
Nitrosomonas eutropha
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 10, 2017 · Synced Jul 23, 2026, 7:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Flourish: Exploring the Early Infant Gut Microbiome

NCT07333482
View directory record Official record
Conditions
Microbiota, Gut Microbiome, Eczema, Microbiome
Interventions
Tailored Recommendations, Consult Call, Educational Email Series
Dietary Supplement · Behavioral
Lead sponsor
Seeding Inc
Industry
Eligibility
0 Months to 3 Months
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Jul 23, 2026, 7:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Infant Microbiome in Diaper Rash

NCT02893501
View directory record Official record
Conditions
Diaper Rash
Interventions
Not listed
Lead sponsor
Kimberly-Clark Corporation
Industry
Eligibility
9 Months to 12 Months
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Aug 17, 2017 · Synced Jul 23, 2026, 7:01 AM EDT
Completed Not applicable Interventional Results available

Hidradenitis Suppurativa (HS) Tunneling Wounds

NCT04648631
View directory record Official record
Conditions
Hidradenitis Suppurativa
Interventions
antibiofilm surfactant wound gel (ABWG)
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 1, 2024 · Synced Jul 23, 2026, 7:01 AM EDT
Recruiting No phase listed Observational

Avera Cancer Sequencing and Analytics Protocol (ASAP)

NCT05142033
View directory record Official record
Conditions
Cancer, Cancer Diagnosis, Early Detection of Cancer, Breast Cancer, Lung Cancer, Colon Cancer, GI Cancer, Gynecologic Cancer, Ovarian Cancer, Endometrial Cancer, CNS Cancer, Hematologic Cancer
Interventions
Not listed
Lead sponsor
Avera McKennan Hospital & University Health Center
Other
Eligibility
18 Years and older
Enrollment
25,000 participants
Timeline
2021 – 2026
U.S. locations
6
States / cities
Marshall, Minnesota • Aberdeen, South Dakota • Mitchell, South Dakota + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jul 23, 2026, 7:01 AM EDT