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ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:43 AM EDT

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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep Architecture Clear all
Completed Phase 4 Interventional Results available

Suvorexant and Sleep/Delirium in ICU Patients

NCT04092894
View directory record Official record
Conditions
Insomnia, Sleep Fragmentation, Sleep Initiation and Maintenance Disorders, Postoperative Delirium
Interventions
Suvorexant 20 mg, Placebo oral tablet
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
60 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Boston, Massachusetts • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Sleep Duration and Architecture on Insulin Sensitivity

NCT01396941
View directory record Official record
Conditions
Insulin Resistance
Interventions
Sleep restriction
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 45 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 19, 2021 · Synced Oct 21, 2026, 7:43 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Sleep and Cognition After Atripla to Stribild Switch

NCT02283060
View directory record Official record
Conditions
HIV
Interventions
Stribild, Atripla
Drug
Lead sponsor
University of Hawaii
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Mar 14, 2016 · Synced Oct 21, 2026, 7:43 AM EDT
Recruiting No phase listed Observational

The Effects of Stellate Ganglion Block Sleep in U.S. Active Duty Service Members and Veterans Receiving Prolonged Exposure Therapy for PTSD

NCT07667309
View directory record Official record
Conditions
Post Traumatic Stress Disorder PTSD
Interventions
Sleep Profiler Headband
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Killeen, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Completed No phase listed Observational

Sleep Architecture and Chemotherapy-Related Fatigue

NCT00178204
View directory record Official record
Conditions
Fatigue, Sleep, Cancer
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 5, 2014 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Phase 2 Interventional Results available

Modafinil, Sleep Architecture and Cocaine Relapse

NCT01137396
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Modafinil, Cognitive Behavioral Therapy
Drug · Behavioral
Lead sponsor
Yale University
Other
Eligibility
25 Years to 50 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 27, 2016 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Not applicable Interventional Results available

Belun Ring Platform With an Improved Algorithm for OSA Assessment

NCT04885062
View directory record Official record
Conditions
Sleep-Disordered Breathing, Sleep Architecture
Interventions
Belun Ring, PSG
Device · Diagnostic Test
Lead sponsor
Belun Technology Company Limited
Other
Eligibility
18 Years to 80 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Recruiting Not applicable Interventional

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)

NCT07385105
View directory record Official record
Conditions
Sleep Architecture, Mild Traumatic Brain Injury, Sleep, Sleep and Circadian Problems
Interventions
Cognitive behavioral Therapy for insomnia (CBT-I)
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 60 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Active, not recruiting Not applicable Interventional

Validation of Belun Ring Gen3 Deep Learning Algorithms With Subxiphoid Body Sensor

NCT06255613
View directory record Official record
Conditions
Sleep-Disordered Breathing, Sleep Architecture, Arrhythmia
Interventions
Belun Ring, Belun Cor
Device
Lead sponsor
Belun Technology Company Limited
Other
Eligibility
18 Years to 80 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Chardon, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Recruiting Not applicable Interventional

Sleep Architecture & Cognition in Focal Epilepsy

NCT05794295
View directory record Official record
Conditions
Focal Epilepsy
Interventions
Acoustic Stimulation (AS), SHAM Stimulation
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 7, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Completed No phase listed Observational

Effects of Sleep Deprivation and Recovery on Cognitive Functions

NCT00179322
View directory record Official record
Conditions
Sleep Deprivation
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
20 Years to 40 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Phase 1Phase 2 Interventional Results available

The Effect of Donepezil (Aricept(Registered Trademark)) on REM Sleep in Children With Autism

NCT00695136
View directory record Official record
Conditions
Autism, Cognition Disorder
Interventions
Donepezil hydrochloride, Increase REM sleep percentage
Drug · Behavioral
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
2 Years to 10 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 24, 2013 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of the Effects of MDMA/Ecstasy on Water Regulation, Sleep, and Cognition.

NCT01053403
View directory record Official record
Conditions
MDMA Discontinuation Syndrome
Interventions
3,4-methylenedioxymethamphetamine or Placebo
Drug
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 31, 2013 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Not applicable Interventional

Effect of Deep Brain Stimulation (DBS) on Sleep Architecture in Patients With Movement Disorders

NCT01169324
View directory record Official record
Conditions
Parkinson's Disease, Tremor, Dystonia
Interventions
Alteration of DBS stimulator settings
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 26, 2019 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Phase 2 Interventional Results available

Sodium Oxybate in Schizophrenia With Insomnia

NCT00594256
View directory record Official record
Conditions
Schizophrenia, Insomnia Related to Schizophrenia (307.42)
Interventions
Sodium Oxybate
Drug
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years to 45 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Orangeburg, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2016 · Synced Oct 21, 2026, 7:43 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Brain Age and Sleep Architecture in Meditators

NCT05513846
View directory record Official record
Conditions
Brain Age
Interventions
DREEM EEG Device, SleepImage Ring
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Withdrawn Phase 2 Interventional

The Effect of Sodium Oxybate on Sleep Architecture

NCT00744393
View directory record Official record
Conditions
Mechanically Ventilated ICU Patients
Interventions
sodium oxybate, placebo
Drug
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 23, 2018 · Synced Oct 21, 2026, 7:43 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Thermodynamic Exposure and Sleep in Military Cadets

NCT07201935
View directory record Official record
Conditions
Cold-water Immersion, High Heat Sauna, Combination of Cold-water Immersion and High Heat Sauna
Interventions
Cold Water Immersion, High Heat Sauna
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 30 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Terminated Phase 2 Interventional Results available

A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With Autism

NCT01887132
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Donepezil, Placebo
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
24 Months to 50 Months
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 25, 2017 · Synced Oct 21, 2026, 7:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators

NCT05026541
View directory record Official record
Conditions
Sleep, Sleep Deprivation, Cognitive Change
Interventions
Nap Practitioners, Shoonya Meditation
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 60 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Completed Not applicable Interventional

Ring-type Pulse Oximeter for Evaluation for Sleep Assessment Study

NCT06221124
View directory record Official record
Conditions
Sleep-Disordered Breathing, Sleep Architecture
Interventions
Belun Ring Pulse Oximeter
Device
Lead sponsor
Belun Technology Company Limited
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2024 · Synced Oct 21, 2026, 7:43 AM EDT
Enrolling by invitation Not applicable Interventional

Effects of Accelerated rTMS on Sleep Architecture in Chronic Insomnia Disorder

NCT07595185
View directory record Official record
Conditions
Insomnia, Chronic Insomnia, Chronic Insomnia Disorder, Sleep Disturbance
Interventions
TMS
Device
Lead sponsor
San Francisco Neurology and Sleep Center
Other
Eligibility
18 Years to 85 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 21, 2026, 7:43 AM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Dexmedetomidine Trial for Effects on Rhythms, Sleep Architecture, and Biomarker Dynamics in Older Adults

NCT07800910
View directory record Official record
Conditions
Sleep, Circadian Rhythm
Interventions
Dexmedetomidine sublingual film, Placebo Sublingual Film
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
65 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 21, 2026, 7:43 AM EDT