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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Sleep Disturbances and Insomnia Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

The Effect of Sleep Loss on Emotion Regulation

NCT05393830
View directory record Official record
Conditions
Sleep, Insomnia, Sleep Deprivation
Interventions
Sleep Restriction
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 40 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 28, 2026, 11:57 PM EDT
Not listed Not applicable Interventional

Sleep Treatment for Addiction Recovery

NCT04198311
View directory record Official record
Conditions
Insomnia, Alcohol Use Disorder, Substance Use Disorders
Interventions
CBT-I
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 9, 2022 · Synced Sep 28, 2026, 11:57 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

The Psychoneuroimmunology of Insomnia

NCT00680771
View directory record Official record
Conditions
Primary Insomnia
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
30 Years to 50 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 16, 2012 · Synced Sep 28, 2026, 11:57 PM EDT
Completed Phase 3 Interventional

6-Month Chronic Efficacy & Safety Study of Eszopiclone in Adult Subjects With Primary Insomnia

NCT00352144
View directory record Official record
Conditions
Primary Insomnia
Interventions
Eszopiclone, Placebo
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
21 Years to 64 Years
Enrollment
830 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
58
States / cities
Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 55 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2012 · Synced Sep 28, 2026, 11:57 PM EDT
Completed Phase 4 Interventional

The Effect of a Once Daily Dose of Atomoxetine (ATX) on ADHD-Related Insomnia in Children and Adolescents

NCT00566371
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Insomnia
Interventions
atomoxetine, placebo
Drug
Lead sponsor
Rhode Island Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 15, 2010 · Synced Sep 28, 2026, 11:57 PM EDT
Not listed Not applicable Interventional

The Clinical and Biochemical Effect of Therapeutic Massage on Fatigue and Insomnia in Women With Breast Cancer Receiving Radiation Therapy

NCT01071109
View directory record Official record
Conditions
Breast Cancer, Fatigue, Insomnia
Interventions
Therapeutic Massage
Procedure
Lead sponsor
Floyd Memorial Hospital and Health Services
Other
Eligibility
18 Years and older · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New Albany, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 18, 2010 · Synced Sep 28, 2026, 11:57 PM EDT
Recruiting Not applicable Interventional

Brief Interventions to Reduce Comorbid Alcohol and Cannabis Misuse and Sleep Impairment in Young Adults (Rest-Up RCT)

NCT06736444
View directory record Official record
Conditions
Insomnia, Alcohol Use, Marijuana Use
Interventions
Brief Behavioral Therapy for Insomnia (BBTI), Brief Alcohol Screening and Intervention for College Students (BASICS), Attention Control
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 29 Years
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 28, 2026, 11:57 PM EDT
Completed Not applicable Interventional

Intervention for Sleep and Pain in Youth

NCT03137147
View directory record Official record
Conditions
Headache Disorders, Migraine Disorders, Insomnia
Interventions
Intervention for Sleep and Pain in Youth
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 17 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 18, 2018 · Synced Sep 28, 2026, 11:57 PM EDT
Completed Not applicable Interventional

Nightmare Deconstruction and Reprocessing Pilot

NCT06904950
View directory record Official record
Conditions
Nightmare
Interventions
Nightmare Deconstruction and Reprocessing
Behavioral
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 64 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
2
States / cities
San Diego, California • Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Sep 28, 2026, 11:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sleep as a Mechanism of Change in Alcohol Use

NCT06286774
View directory record Official record
Conditions
Insomnia, Alcohol; Harmful Use
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 49 Years
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 28, 2026, 11:57 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms Underlying the Sleep Promoting Effect of Cherry Juice Standardized to Its Proanthocyanidin Content

NCT01669317
View directory record Official record
Conditions
Insomnia, Sleep Problem
Interventions
8-ounce glass of cherry juice, Artificial Cherry Juice
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
65 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 17, 2015 · Synced Sep 28, 2026, 11:57 PM EDT
Terminated Not applicable Interventional

Effect of Holofiber Socks and Bedding on Pain and Quality of Sleep in Subjects With Chronic Foot Pain

NCT00458497
View directory record Official record
Conditions
Diabetic Neuropathy, Arthritis, Peripheral Arterial Disease, Plantar Fasciitis
Interventions
Holofiber fabric, PET fabric
Device
Lead sponsor
Southern California Institute for Research and Education
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2010 · Synced Sep 28, 2026, 11:57 PM EDT
Recruiting Not applicable Interventional

Sleep Mechanisms Of Regulating Emotions

NCT06373718
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Sep 28, 2026, 11:57 PM EDT
Completed Not applicable Interventional

Behavioral Insomnia Therapy for Fibromyalgia

NCT00000397
View directory record Official record
Conditions
Fibromyalgia, Insomnia
Interventions
Behavioral insomnia therapy
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2004
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 20, 2014 · Synced Sep 28, 2026, 11:57 PM EDT
Completed Phase 3 Interventional Results available

SM-1 vs 2 Comparators and Placebo in Participants With a History of Transient Insomnia.

NCT03331042
View directory record Official record
Conditions
Transient Insomnia
Interventions
SM-1, D+Z, D+L, Placebo
Drug
Lead sponsor
Sequential Medicine Ltd
Industry
Eligibility
18 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Atlanta, Georgia • New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2019 · Synced Sep 28, 2026, 11:57 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effects of Melatonin on Insomnia Symptoms in Older Adults

NCT00230737
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
Melatonin 0.4 mg, Melatonin 4.0 mg, Placebo
Drug
Lead sponsor
Nalaka Gooneratne
Other
Eligibility
65 Years and older
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 7, 2017 · Synced Sep 28, 2026, 11:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

NCT05516277
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Insomnia, Cardiovascular Diseases, Metabolic Disease
Interventions
Behavioral Sleep Education Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 28, 2026, 11:57 PM EDT
Active, not recruiting Not applicable Interventional

The Impact of Technology in Obstructive Sleep Apnea Myofunctional Therapy

NCT06905951
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA), Snoring, Sleep Quality
Interventions
Exercise
Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Sep 28, 2026, 11:57 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Changes in 24-hour Activity Cycle Behaviors During a Time-Restricted Eating Intervention in College-Aged Women

NCT07520786
View directory record Official record
Conditions
Sleep Quality, Compliance, Physical Activity, Sedentary Behaviors, Sleep Duration
Interventions
Time Restricted Eating, Control
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 26 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 28, 2026, 11:57 PM EDT
Completed Not applicable Interventional Results available

Sleep Treatment Education Program for Young Adult Cancer Survivors (STEP-YA)

NCT05358951
View directory record Official record
Conditions
Insomnia, Insomnia Due to Medical Condition, Cancer
Interventions
STEP-YA with Coaching, STEP-YA without Coaching
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
20 Years to 39 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 26, 2026 · Synced Sep 28, 2026, 11:57 PM EDT
Completed Not applicable Interventional Results available

MIDAS Cluster Randomized Controlled Trial of Implementation Strategies to Optimize Use of Medications in VA Clinical Settings

NCT05065502
View directory record Official record
Conditions
Polypharmacy, Insomnia, Anticoagulants
Interventions
Academic Detailing (AD), LEAP
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Sep 28, 2026, 11:57 PM EDT
Recruiting Phase 2 Interventional

Effects of Lemborexant on Insomnia and Its Relationship to Mood and Behavior on Opioid Use Disorder Subjects

NCT06981195
View directory record Official record
Conditions
Opioid Use Disorder, Opioid Use, Insomnia, Orexin Antagonist
Interventions
Placebo, Lemborexant 10 MG
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Sep 28, 2026, 11:57 PM EDT
Enrolling by invitation Not applicable Interventional

Experimental Trial of an Employment-Based Housing Program for Adults at Risk of Homelessness

NCT07470372
View directory record Official record
Conditions
Emergency Department Visits, Housing Stability, Employment, Sleep Quality, Health-Related Quality-of-Life
Interventions
Employment-Based Housing, Vocational Services, Resources
Other
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 28, 2026, 11:57 PM EDT
Terminated Phase 2 Interventional Results available

The Effects of Suvorexant on Sleep, Stress, and Cue-reactivity in Methamphetamine Use Disorder

NCT05711862
View directory record Official record
Conditions
Methamphetamine Use Disorder
Interventions
suvorexant (SUVO), Placebo
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 28, 2025 · Synced Sep 28, 2026, 11:57 PM EDT