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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:27 AM EDT

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Showing 1–24 of 63 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep Restriction Clear all
Not yet recruiting Early Phase 1 Interventional

Kava Aging and Mobility Study

NCT07219186
View directory record Official record
Conditions
Old Adults, Sleep Quality, Kava, Mobility Impairment, Physical Activity and Stress, Physical Impairment, Sedentary Lifestyle in Patients Over 70
Interventions
AB-free kava, Placebo
Drug · Other
Lead sponsor
University of Florida
Other
Eligibility
70 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 21, 2026, 6:27 AM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Hormonal Mechanisms of Sleep Restriction - Axis Study in Older Men and Postmenopausal Women

NCT04037605
View directory record Official record
Conditions
Sleep Restriction
Interventions
Ketoconazole Pill (also known as nizoral), Ganirelix, Dexamethasone Pill, Dexamethasone injection, Cosyntropin Injectable Product, Recombinant Human Luteinizing Hormone (also known as luveris), Hydrocortisone Injection (also known as solu-cortef), Gonadorelin (also known as Lutrepulse), Corticorelin (also known as Acthrel), Placebo oral tablet, Saline Solution, Saline solution for injection
Drug
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
60 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Oct 21, 2026, 6:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Countermeasures to Circadian Misalignment

NCT04966351
View directory record Official record
Conditions
Circadian Rhythm Sleep Disorder of Shift Work Type, Metabolic Disease, Insulin Sensitivity
Interventions
Time-restricted feeding, Circadian Misalignment
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 35 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Chronic Circadian Disruption vs. Chronic Sleep Restriction on Metabolism

NCT02171273
View directory record Official record
Conditions
Aging, Sleep Restriction, Circadian Disruption
Interventions
Circadian Disruption, Sleep Restriction, Control
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2019 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Chronic Moderate Sleep Restriction in Older Adults

NCT01642719
View directory record Official record
Conditions
Sleep Disturbance, Aging
Interventions
Sleep restriction, Non-sleep restriction
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
4
States / cities
Tucson, Arizona • Los Angeles, California • Brooklyn, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Restriction and Postprandial Lipemia

NCT05713370
View directory record Official record
Conditions
Sleep Deprivation, Obesity
Interventions
high fat meal
Dietary Supplement
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 45 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Not applicable Interventional

Incorporating Flow Limitation Into the Diagnosis and Quantification of Sleep Disordered Breathing

NCT00004569
View directory record Official record
Conditions
Sleep-Disordered Breathing
Interventions
Non-invasive technique to diagnose and quantitate sleep-disordered breathing
Procedure
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Phenotypic and Genotypic Markers of Performance Vulnerability to Sleep Loss

NCT02130791
View directory record Official record
Conditions
Sleep Restriction Then Total Sleep Deprivation, Total Sleep Deprivation Then Sleep Restriction
Interventions
Sleep
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 50 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Oct 21, 2026, 6:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Sleep Restriction on Blood Pressure Reactivity

NCT07489417
View directory record Official record
Conditions
Sleep, Blood Pressure
Interventions
Sleep Restriction
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 45 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interaction of Chronic Sleep Restriction and Circadian Misalignment on Sleep and Neuro-cognitive Performance

NCT00438438
View directory record Official record
Conditions
Healthy
Interventions
forced desynchrony protocol with sleep restriction
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 2, 2011 · Synced Oct 21, 2026, 6:27 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Partial Sleep Restriction in Chronic Low Back Pain: A Feasibility Study

NCT07008924
View directory record Official record
Conditions
Chronic Low-back Pain, Insomnia, Sleep
Interventions
No intervention is provided. We monitor natural recovery to full sleep.
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
25 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Restriction and Energy Expenditure

NCT01751581
View directory record Official record
Conditions
Obesity
Interventions
Short Sleep, Habitual sleep
Behavioral
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 2, 2013 · Synced Oct 21, 2026, 6:27 AM EDT
Recruiting Not applicable Interventional

Sleep Restriction Therapy (SRT) for Sleep Problems in Children With Autism

NCT06627205
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD), Autism
Interventions
Sleep Restriction Therapy
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
6 Years to 12 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 16, 2025 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Modafinil to Counteract the Adverse Metabolic Consequences of Sleep Restriction

NCT00895570
View directory record Official record
Conditions
Sleep Restriction, Impaired Glucose Metabolism
Interventions
modafinil, placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
20 Years to 35 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 8, 2009 · Synced Oct 21, 2026, 6:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

NCT05309473
View directory record Official record
Conditions
Sleep Deprivation, Sleep Restriction, Acoustic Stimulation, Performance, Alertness
Interventions
Philips SmartSleep Acoustic Stimulation Device, Sham (no Acoustic Stimulation)
Device
Lead sponsor
Walter Reed Army Institute of Research (WRAIR)
Federal
Eligibility
18 Years to 39 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Sleep Restriction on Adipose Tissue and Skeletal Muscle Insulin Sensitivity

NCT04286451
View directory record Official record
Conditions
Sleep Disturbance, Postmenopausal Symptoms, Insulin Sensitivity, Cardiovascular Risk Factor
Interventions
Sleep Restriction, Habitual Sleep
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Duration Required to Restore Performance During Chronic Sleep Restriction

NCT01581125
View directory record Official record
Conditions
Sleep, Sleep Deprivation, Insufficient Sleep Syndrome
Interventions
Sleep:wake 1, Sleep:wake 2
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 18, 2016 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease

NCT05138848
View directory record Official record
Conditions
Alzheimer Disease, Late Onset, Mild Cognitive Impairment, Sleep, Cognitive Change, Amyloid
Interventions
Time in Bed Restriction, Sleep Schedule
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years to 85 Years
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 21, 2026, 6:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cardiovascular Risk and Circadian Misalignment in Short Sleepers - Role of Extended Eating Period

NCT06070194
View directory record Official record
Conditions
Sleep Deprivation
Interventions
Time restricted eating (TRE)
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 45 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sleep Disruption Induced Impairments in Bone Formation

NCT03733483
View directory record Official record
Conditions
Healthy
Interventions
Sleep Deprivation
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
20 Years to 65 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 12, 2021 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Outlooks by Restriction of Diet and Sleep

NCT02413866
View directory record Official record
Conditions
Weight
Interventions
Calorie restriction only, Sleep & calorie restriction
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
35 Years to 55 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 19, 2019 · Synced Oct 21, 2026, 6:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treatments for Insomnia: Mediators, Moderators and Quality of Life

NCT02117388
View directory record Official record
Conditions
Insomnia
Interventions
Sleep Restriction, Cognitive Behavioral Therapy, Combined Therapy
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
60 Years and older
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 20, 2019 · Synced Oct 21, 2026, 6:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Changes in 24-hour Activity Cycle Behaviors During a Time-Restricted Eating Intervention in College-Aged Women

NCT07520786
View directory record Official record
Conditions
Sleep Quality, Compliance, Physical Activity, Sedentary Behaviors, Sleep Duration
Interventions
Time Restricted Eating, Control
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 26 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 21, 2026, 6:27 AM EDT
Recruiting Not applicable Interventional

Healthy Lifestyles in Bipolar Disorder: Bay Area Study

NCT06555406
View directory record Official record
Conditions
Bipolar Disorder, Time Restricted Eating
Interventions
Time-restricted eating for 8 weeks
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Oct 21, 2026, 6:27 AM EDT