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Showing 1–24 of 63 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Sleep Restriction Clear all
Recruiting Not applicable Interventional

Healthy Lifestyles for Bipolar Disorder

NCT06188754
View directory record Official record
Conditions
Time Restricted Eating, Diet, Mediterranean
Interventions
Time restricted eating, Mediterranean diet
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 5, 2026, 10:20 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.

NCT06075914
View directory record Official record
Conditions
Sleep Deprivation, Nutritional Intervention
Interventions
Ketogenic Intervention, Mediterranean Intervention, Placebo, Ketone Ester
Other · Dietary Supplement
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Chronic Circadian Disruption vs. Chronic Sleep Restriction on Metabolism

NCT02171273
View directory record Official record
Conditions
Aging, Sleep Restriction, Circadian Disruption
Interventions
Circadian Disruption, Sleep Restriction, Control
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 19, 2019 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Metabolic Impact of Time Restricted Feeding

NCT03129581
View directory record Official record
Conditions
Obesity, Diet Modification
Interventions
Dietary Counseling
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 22, 2022 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Timing on Energy Intake and Energy Expenditure

NCT05096585
View directory record Official record
Conditions
Obesity
Interventions
Delayed bedtime sleep restriction, Early wake sleep restriction
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 45 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 9, 2023 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Duration Required to Restore Performance During Chronic Sleep Restriction

NCT01581125
View directory record Official record
Conditions
Sleep, Sleep Deprivation, Insufficient Sleep Syndrome
Interventions
Sleep:wake 1, Sleep:wake 2
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 17, 2016 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Sleep Restriction on Adipose Tissue and Skeletal Muscle Insulin Sensitivity

NCT04286451
View directory record Official record
Conditions
Sleep Disturbance, Postmenopausal Symptoms, Insulin Sensitivity, Cardiovascular Risk Factor
Interventions
Sleep Restriction, Habitual Sleep
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 15, 2022 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Energy and Cognition

NCT01603550
View directory record Official record
Conditions
Energy Restriction, Sleep Deprivation
Interventions
Sleep Deprivation, Energy Restriction
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 5, 2016 · Synced Sep 5, 2026, 10:20 PM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Sleep and Inflammatory Resolution Pathway

NCT03377543
View directory record Official record
Conditions
Inflammatory Response, Inflammation, Sleep, Sleep Restriction
Interventions
Aspirin, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Sep 5, 2026, 10:20 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Sleep Restriction on Blood Pressure Reactivity

NCT07489417
View directory record Official record
Conditions
Sleep, Blood Pressure
Interventions
Sleep Restriction
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 45 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Sep 5, 2026, 10:20 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Changes in 24-hour Activity Cycle Behaviors During a Time-Restricted Eating Intervention in College-Aged Women

NCT07520786
View directory record Official record
Conditions
Sleep Quality, Compliance, Physical Activity, Sedentary Behaviors, Sleep Duration
Interventions
Time Restricted Eating, Control
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 26 Years · Female only
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Restriction and Postprandial Lipemia

NCT05713370
View directory record Official record
Conditions
Sleep Deprivation, Obesity
Interventions
high fat meal
Dietary Supplement
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 45 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 30, 2024 · Synced Sep 5, 2026, 10:20 PM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers

Hormonal Mechanisms of Sleep Restriction - Axis Study

NCT03142893
View directory record Official record
Conditions
Sleep Restriction
Interventions
Ketoconazole Pill, Ganirelix, Dexamethasone, Dexamethasone Injection, Cosyntropin Injectable Product, Recombinant Human Luteinizing Hormone, Hydrocortisone Injection, Gonadorelin, Corticorelin, Placebo oral capsule, Saline Solution, Saline Solution for Injection
Drug
Lead sponsor
Peter y. Liu
Other
Eligibility
22 Years to 45 Years · Male only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Weight Outlooks by Restriction of Diet and Sleep

NCT02413866
View directory record Official record
Conditions
Weight
Interventions
Calorie restriction only, Sleep & calorie restriction
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
35 Years to 55 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interaction of Chronic Sleep Restriction and Circadian Misalignment on Sleep and Neuro-cognitive Performance

NCT00438438
View directory record Official record
Conditions
Healthy
Interventions
forced desynchrony protocol with sleep restriction
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 1, 2011 · Synced Sep 5, 2026, 10:20 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sleep and Metabolism

NCT05775627
View directory record Official record
Conditions
Sleep Deprivation, Obesity, Glucose Intolerance, Weight Gain, Food Selection
Interventions
Sleep Restriction
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Sep 5, 2026, 10:20 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cardiovascular Risk and Circadian Misalignment in Short Sleepers - Role of Extended Eating Period

NCT06070194
View directory record Official record
Conditions
Sleep Deprivation
Interventions
Time restricted eating (TRE)
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 45 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Sep 5, 2026, 10:20 PM EDT
Recruiting Early Phase 1 Interventional

Time Restricted Eating in Sleep Apnea

NCT06047496
View directory record Official record
Conditions
Time Restricted Eating, Obstructive Sleep Apnea
Interventions
Time restricted eating
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 70 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jan 15, 2024 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of SmartSleep Technology for Improving the Efficiency and Restorative Quality of Sleep in Healthy Adults

NCT03911154
View directory record Official record
Conditions
Sleep
Interventions
Philips SmartSleep Technology--Continuous Fixed Interval modality, Philips SmartSleep Technology--Block modality, Philips SmartSleep Technology--In-Phase Adjustable modality
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
30 Years to 55 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2022 · Synced Sep 5, 2026, 10:20 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Countermeasures to Circadian Misalignment

NCT04966351
View directory record Official record
Conditions
Circadian Rhythm Sleep Disorder of Shift Work Type, Metabolic Disease, Insulin Sensitivity
Interventions
Time-restricted feeding, Circadian Misalignment
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 35 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 23, 2025 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sex-specific Effect of Restricted Sleep on Brain Health

NCT05920759
View directory record Official record
Conditions
Cerebrovascular Circulation
Interventions
Cerebral blood flow
Diagnostic Test
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 45 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Sep 5, 2026, 10:20 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction

NCT05519644
View directory record Official record
Conditions
Sleep Deprivation
Interventions
Sleep Deprivation, Heart Rate, Sleep Monitoring, Diet, Exercise Performance, Surveys, McGill Pain Questionnaire, Shortened Profile of Mood States, Pittsburg Sleep Index, Cognitive performance, Marksmanship Performance, Quick Board, Advanced Medical Technologies Inc, Jump Test, CGM/CKM, Blood Draw, Ketone Supplement
Other · Behavioral · Biological + 1 more
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Repeating Patterns of Sleep Restriction and Recovery

NCT01523691
View directory record Official record
Conditions
Healthy
Interventions
Repeated sleep restriction and recovery, Control sleep
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 35 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Sep 5, 2026, 10:20 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treatments for Insomnia: Mediators, Moderators and Quality of Life

NCT02117388
View directory record Official record
Conditions
Insomnia
Interventions
Sleep Restriction, Cognitive Behavioral Therapy, Combined Therapy
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
60 Years and older
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2019 · Synced Sep 5, 2026, 10:20 PM EDT