Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Sep 5, 2026, 2:55 PM EDT

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Showing 1–24 of 62 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Obstructive Sleep Apnea, Snoring
Interventions
LinguaFlex Tongue Retractor (LTR)
Device
Lead sponsor
Linguaflex, Inc.
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
3
States / cities
Brighton, Massachusetts • Morgantown, West Virginia • Milwaukee, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Disposable Device NAS to Treat Obstructive Sleep Apnea and Snoring

NCT02928770
Conditions
Obstructive Sleep Apnea, Snoring
Interventions
Nastent
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Redwood City, California
Completed Not applicable Interventional Results available

Validation of Safety and Efficacy for Night Shift Therapy

NCT02032706
Conditions
Obstructive Sleep Apnea
Interventions
Deliver therapy when the supine position is detected
Device
Lead sponsor
Advanced Brain Monitoring, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Murrieta, California
Conditions
Snoring, Sleep Apnea Syndromes
Interventions
KEEPASLEEP enhanced breathing device
Device
Lead sponsor
Miller, Chipp St. Kevin, M.D.
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Santa Monica, California
Conditions
Sleep Apnea, Obstructive, Sleep Apnea, Sleep, Snoring
Interventions
Transoral Neurostimulation Device (Snoozeal)
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
2
States / cities
San Diego, California
Conditions
Snoring, Apnea, Obstructive, Upper Airway Resistance Syndrome, Sleep-Disordered Breathing
Interventions
Vivos Grow/Vivos Way Device
Device
Lead sponsor
Vivos BioTechnologies, Inc.
Industry
Eligibility
7 Years to 17 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
4
States / cities
Colorado Springs, Colorado • Panama City Beach, Florida • Garland, Texas + 1 more
Conditions
Obstructive Sleep Apnea
Interventions
Respiratory muscle strength training, Sham respiratory muscle strength training
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Obstructive Sleep Apnea, OSA, Apnea, Apnea, Obstructive, Apnea, Obstructive Sleep, Apnea+Hypopnea, Hypopnea, Sleep
Interventions
Hypoglossal Nerve Stimulation
Device
Lead sponsor
LivaNova
Industry
Eligibility
22 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
19
States / cities
Birmingham, Alabama • Tucson, Arizona • Roseville, California + 16 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Apnea Hypopnea Index Severity Versus Head Position During Sleep

NCT04086407
Conditions
Sleep Disordered Breathing, Sleep Hypopnea, Sleep Apnea, Sleep Apnea, Obstructive, Snoring
Interventions
Dual-axis inclinometer attached to the subject's forehead with tape
Device
Lead sponsor
Sleep Systems
Industry
Eligibility
21 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Worcester, Massachusetts
Conditions
Mild Obstructive Sleep Apnea, Snoring
Interventions
Mouth Tape
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Baltimore, Maryland
Recruiting Not applicable Interventional Accepts healthy volunteers

IOA Preventing Occlusal Changes With MAD Use

NCT07103941
Conditions
Sleep Related Breathing Disorder, Snoring, Obstructive Sleep Apnea (OSA), Open Bite, Occlusal Changes, Tooth Migration, Posterior Open Bite
Interventions
AM Aligner, Exercise
Device · Behavioral
Lead sponsor
Isabel Moreno Hay
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Snoring, Mouth Breathing, Daytime Sleepiness, Periodontitis
Interventions
Oral appliance therapy plus scaling and root planing on left or right of mouth
Device
Lead sponsor
Texas A&M University
Other
Eligibility
18 Years to 85 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Snoring
Interventions
PVT-192
Device
Lead sponsor
Vidya Raman
Other
Eligibility
6 Years to 18 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Completed Not applicable Interventional Results available

Childhood Adenotonsillectomy Study for Children With OSAS

NCT00560859
Conditions
Obstructive Sleep Apnea, Snoring
Interventions
Adenotonsillectomy (AT) - removal of adenoids and tonsils, Watchful Waiting
Procedure · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
5 Years to 9 Years
Enrollment
453 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
6
States / cities
Boston, Massachusetts • St Louis, Missouri • New York, New York + 3 more
Recruiting Not applicable Interventional

DISE: Phenotyping Obstruction Patterns

NCT05050383
Conditions
Obstructive Sleep Apnea
Interventions
Pharyngeal Manometry, Submental Ultrasound
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Conditions
Hepatic Encephalopathy, Covert Hepatic Encephalopathy, Cirrhosis, Sleep Disturbances and Insomnia
Interventions
Melatonin tablet 3 mg once daily, Thiamine
Dietary Supplement
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Sleep Related Breathing Disorder, Upper Airway Resistance Syndrome, Obstructive Sleep Apnea
Interventions
Cold ablation inferior turbinate reduction
Procedure
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
Up to 18 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Columbia, Missouri
Completed No phase listed Observational Accepts healthy volunteers

Snoring in Pregnancy and Adverse Maternal and Fetal Outcomes

NCT01030003
Conditions
Sleep Apnea Syndromes
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
1,685 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Terminated Early Phase 1 Interventional

Neostigmine For Snoring During DISE

NCT03316963
Conditions
Snoring
Interventions
Neostigmine Methylsulfate
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Sleep Disordered Breathing
Interventions
Soft earplugs are worn during sleep study
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
407 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Obstructive Sleep Apnea (OSA), Snoring, Sleep Quality
Interventions
Exercise
Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Snoring, Sleep Apnea, Obstructive
Interventions
Genioglossis Strength Trainer, Placebo Genioglossis Strength Trainer
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional Accepts healthy volunteers

Study of Nasal Airflow Pressure Optimization to Resolve Excessive Snoring

NCT01949584
Conditions
Snoring
Interventions
nasal continuous positive airway pressure less than or equal to 6 cm H2O
Device
Lead sponsor
inSleep Technologies, LLC
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
3
States / cities
Atlanta, Georgia • Baltimore, Maryland • Lanham, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

In Home Assessment of Three Anti-Snoring Devices, a Cross Over Study

NCT03333876
Conditions
Snoring
Interventions
Nasal Dilator, Mandibular Advancement, Positional Therapy
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 70 Years
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Murrysville, Pennsylvania