- Conditions
- Spasticity as Sequela of Stroke, Spastic Cerebral Palsy, Spasticity, Muscle
- Interventions
- stereotactic radiosurgery (SRS) dorsal root rhizotomy radiomodulation, Sham
- Radiation · Other
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 16 Years and older
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2026
- U.S. locations
- 2
- States / cities
- Winter Park, Florida • Columbus, Ohio
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Showing 1–24
of 72
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Cerebral Palsy, Spastic, Telemedicine
- Interventions
- Telehealth home exercise program
- Behavioral
- Lead sponsor
- University of Kansas Medical Center
- Other
- Eligibility
- 11 Years to 18 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Kansas City, Kansas
- Conditions
- Cerebral Palsy, CP, Spastic Cerebral Palsy
- Interventions
- Autologous UCB Reinfusion, Placebo
- Biological · Other
- Lead sponsor
- Joanne Kurtzberg, MD
- Other
- Eligibility
- 12 Months to 6 Years
- Enrollment
- 63 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2016
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Sjogren-Larsson Syndrome (SLS)
- Interventions
- Not listed
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- Not listed
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2023
- U.S. locations
- 2
- States / cities
- Omaha, Nebraska • Pittsburgh, Pennsylvania
- Conditions
- Spinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, Spastic
- Interventions
- Robotic gait training, Robotic gait training and low-frequency transspinal stimulation, Robotic gait training and high-frequency transspinal stimulation
- Other · Device
- Lead sponsor
- City University of New York
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 2
- States / cities
- Staten Island, New York • The Bronx, New York
- Conditions
- Diplegia, Spastic
- Interventions
- Not listed
- Lead sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
- NIH
- Eligibility
- Not listed
- Enrollment
- 144 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2001 – 2005
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland
- Conditions
- AMN, AMN Gene Mutation, X-ALD
- Interventions
- Natural History Observation
- Other
- Lead sponsor
- SwanBio Therapeutics, Inc.
- Industry
- Eligibility
- 18 Years and older · Male only
- Enrollment
- 65 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 4
- States / cities
- Stanford, California • Boston, Massachusetts • New York, New York + 1 more
- Conditions
- Cerebral Palsy
- Interventions
- SPIO® Core-MAX® Expedition thoracolumbosacral orthosis, Standard Care Therapy option
- Device · Other
- Lead sponsor
- Medical College of Wisconsin
- Other
- Eligibility
- 6 Months to 18 Months
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin
- Conditions
- Cerebral Palsy, Gait Disorders, Neurologic
- Interventions
- mPAD (or TPAD) Pelvic Assist Device, No Intervention
- Device
- Lead sponsor
- Altec Inc.
- Industry
- Eligibility
- 6 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2021
- U.S. locations
- 2
- States / cities
- Natick, Massachusetts • New York, New York
- Conditions
- Cerebral Palsy Spastic Diplegia
- Interventions
- Short Burst Interval Locomotor Treadmill Training (SBLTT)
- Behavioral
- Lead sponsor
- Seattle Children's Hospital
- Other
- Eligibility
- 5 Years to 12 Years
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2016
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Muscle Spasticity
- Interventions
- Hyaluronidase, Placebo
- Drug
- Lead sponsor
- Johns Hopkins University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2027
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Spastic Diplegic Cerebral Palsy
- Interventions
- NMES Strength Training, Volitional Strength Training
- Device · Other
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 7 Years to 12 Years
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2004
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Cerebral Palsy
- Interventions
- Treadmill Training, Whole Body Vibration & Treadmill Training
- Other
- Lead sponsor
- Georgia State University
- Other
- Eligibility
- 6 Years to 17 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2026
- U.S. locations
- 1
- States / cities
- Atlanta, Georgia
- Conditions
- Cerebral Palsy Spastic Diplegia
- Interventions
- FES, Cycling
- Device · Other
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 10 Years to 18 Years
- Enrollment
- 39 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2016
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Spastic Diplegic Cerebral Palsy
- Interventions
- Stationary Cycling
- Other
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 7 Years to 18 Years
- Enrollment
- 64 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2003 – 2006
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Cerebral Palsy, Spastic
- Interventions
- Vibration Platform, Placebo Platform
- Device
- Lead sponsor
- University of Georgia
- Other
- Eligibility
- 5 Years to 11 Years
- Enrollment
- 44 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2026
- U.S. locations
- 1
- States / cities
- Athens, Georgia
- Conditions
- Cerebral Palsy, Dystonia, Hypertonia, Spasticity, Movement Disorders
- Interventions
- Sanger EMG Biofeedback Device
- Device
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 0 Years to 21 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2024
- U.S. locations
- 1
- States / cities
- Los Angeles, California
- Conditions
- Pediatrics, Muscle Spasticity, Cerebral Palsy
- Interventions
- Botulinum Toxin Type A
- Biological
- Lead sponsor
- Allergan
- Industry
- Eligibility
- 2 Years to 17 Years
- Enrollment
- 370 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2018
- U.S. locations
- 26
- States / cities
- Pasadena, California • Pomona, California • San Diego, California + 21 more
- Conditions
- Spasticity, Cerebral Palsy
- Interventions
- baclofen
- Drug
- Lead sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- NIH
- Eligibility
- 2 Years to 16 Years
- Enrollment
- 61 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 11
- States / cities
- Chicago, Illinois • New Orleans, Louisiana • Baltimore, Maryland + 8 more
- Conditions
- Stroke, Ischemic, Stroke Hemorrhagic, Spastic Hemiparesis
- Interventions
- Contralateral C7 root transfer for the treatment of spastic hemiparesis.
- Procedure
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 95 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Lebanon, New Hampshire
- Conditions
- Cerebral Palsy, Spasticity
- Interventions
- IncobotulinumtoxinA (8 Units per kg body weight), IncobotulinumtoxinA (6 Units per kg body weight), IncobotulinumtoxinA (2 Units per kg body weight)
- Drug
- Lead sponsor
- Merz Pharmaceuticals GmbH
- Industry
- Eligibility
- 2 Years to 17 Years
- Enrollment
- 351 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2018
- U.S. locations
- 6
- States / cities
- Gulf Breeze, Florida • Loxahatchee Groves, Florida • Savannah, Georgia + 3 more
- Conditions
- Spastic Diplegia
- Interventions
- 3Tesla MRI with DTI-MRI and rsfcMRI under general anesthesia
- Procedure
- Lead sponsor
- The University of Texas Health Science Center, Houston
- Other
- Eligibility
- 3 Years to 18 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2031
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Spastic Cerebral Palsy
- Interventions
- IntelliStretch
- Device
- Lead sponsor
- University of Maryland, Baltimore
- Other
- Eligibility
- 6 Years to 17 Years
- Enrollment
- 5 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Stroke, Cerebrovascular Accident (CVA), Hemiparesis, Spasticity as Sequela of Stroke, Muscle Spasticity, Upper Extremity Paralysis
- Interventions
- sham Doublestim, anodal Doublestim
- Device
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Manhasset, New York