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ClinicalTrials.gov public records Last synced Oct 24, 2026, 2:43 AM EDT

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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Spastic Diplegia Clear all
Enrolling by invitation Not applicable Interventional

Little NIRVANA for Pediatric Pain and Anxiety

NCT06795126
View directory record Official record
Conditions
Acute Pain, Procedural Anxiety, Pediatric ALL, Emergency Medicine, IV Access
Interventions
Little NIRVANA
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
2 Years to 8 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 24, 2026, 2:43 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Healthy Little Eyes

NCT05971446
View directory record Official record
Conditions
Hypoxic-Ischemic Encephalopathy, Neonatal Encephalopathy, Encephalopathy
Interventions
Visual Evoked Potential (VEP), Electroretinogram (ERG)
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
Up to 36 Months
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2029
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 24, 2026, 2:43 AM EDT
Completed Not applicable Interventional

Little Flower Yoga for Kids: Evaluation of a Yoga and Mindfulness Program for Children With Increased Levels of Emotion Dysregulation and Inattention

NCT02829528
View directory record Official record
Conditions
ADHD
Interventions
Little Flower Yoga For Kids
Behavioral
Lead sponsor
New York University
Other
Eligibility
5 Years to 7 Years · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 4, 2022 · Synced Oct 24, 2026, 2:43 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Molecular Predisposition to Hereditary Nonpolyposis Colon Cancer (HNPCC)

NCT01447199
View directory record Official record
Conditions
Bladder Cancer, Colorectal Cancer, Endometrial Cancer, Kidney Cancer, Skin Cancer, Uterus Cancer
Interventions
Health and Diet Questionnaire
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1994 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2020 · Synced Oct 24, 2026, 2:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wakȟáŋyeža (Little Holy One)

NCT04201184
View directory record Official record
Conditions
Suicide, Trauma, Psychological, Parenting
Interventions
Newly created cultural components, adapted Family Spirit lessons, adapted CETA modules, Active nutrition control
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Poplar, Montana
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Oct 24, 2026, 2:43 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Evaluation of Brain MRI Changes in Cerebral Palsy Patients

NCT07433647
View directory record Official record
Conditions
Cerebral Palsy, Spastic Diplegia, Spastic Quadriplegia, Spastic Hemiplegia
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 24, 2026, 2:43 AM EDT
Completed Phase 1Phase 2 Interventional

ADX-629 Therapy for Sjogren-Larsson Syndrome

NCT05443685
View directory record Official record
Conditions
Sjogren-Larsson Syndrome
Interventions
ADX-629
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
5 Years to 50 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 24, 2026, 2:43 AM EDT
Completed Not applicable Interventional

FES Assisted Cycling in Children With CP

NCT04688424
View directory record Official record
Conditions
Cerebral Palsy Spastic Diplegia
Interventions
FES, Cycling
Device · Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
10 Years to 18 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 30, 2020 · Synced Oct 24, 2026, 2:43 AM EDT
Completed No phase listed Observational Results available

The Role of Cerebellar Hyperactivity in Parkinson's Disease

NCT02349789
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 15, 2019 · Synced Oct 24, 2026, 2:43 AM EDT
Completed Not applicable Interventional

Study of a Stationary Cycling Intervention for Children With Spastic Diplegic Cerebral Palsy

NCT00401154
View directory record Official record
Conditions
Spastic Diplegic Cerebral Palsy
Interventions
Stationary Cycling
Other
Lead sponsor
University of Southern California
Other
Eligibility
7 Years to 18 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 8, 2014 · Synced Oct 24, 2026, 2:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Bottle Optimization Testing Tiny Little Eaters Study

NCT07665983
View directory record Official record
Conditions
Childhood Obesity
Interventions
Feeding
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
4 Months and older
Enrollment
440 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 24, 2026, 2:43 AM EDT
Not listed Phase 1 Interventional

Strength Training Using Neuromuscular Electrical Stimulation For Children With Cerebral Palsy

NCT00356343
View directory record Official record
Conditions
Spastic Diplegic Cerebral Palsy
Interventions
NMES Strength Training, Volitional Strength Training
Device · Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
7 Years to 12 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 11, 2011 · Synced Oct 24, 2026, 2:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Control of Movements in Cerebral Palsy

NCT00076596
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
6 Years to 30 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
2
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 24, 2026, 2:43 AM EDT
Recruiting Not applicable Interventional

Cortical Plasticity in Spastic Diplegia After Selective Dorsal Rhizotomy

NCT02535936
View directory record Official record
Conditions
Spastic Diplegia
Interventions
3Tesla MRI with DTI-MRI and rsfcMRI under general anesthesia
Procedure
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
3 Years to 18 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2031
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 11, 2024 · Synced Oct 24, 2026, 2:43 AM EDT
Completed Not applicable Interventional Results available

Little Cigar and Cigarillo Warnings Among US Adults Who Use LCCs

NCT05849051
View directory record Official record
Conditions
Tobacco Use
Interventions
Newly developed warnings with images at 30% size, FDA proposed text-only warnings at 30% size
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
21 Years and older
Enrollment
1,029 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2025 · Synced Oct 24, 2026, 2:43 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Little Lungs Study

NCT06855043
View directory record Official record
Conditions
Invasive Mechanical Ventilation, Severe Respiratory Distress Syndrome
Interventions
Calfactant, Budesonide
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
7 Days to 14 Days
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 24, 2026, 2:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Precision Gait Retraining for Children With Cerebral Palsy

NCT04717323
View directory record Official record
Conditions
Cerebral Palsy, Gait Disorders, Neurologic
Interventions
mPAD (or TPAD) Pelvic Assist Device, No Intervention
Device
Lead sponsor
Altec Inc.
Industry
Eligibility
6 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Natick, Massachusetts • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 4, 2022 · Synced Oct 24, 2026, 2:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Community-Based Participatory Research to Improve Health and Quality of Life of Latino Youth: Every Little Step Counts

NCT01236794
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Lifestyle Education Sessions and Youth Exercise Sessions
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
14 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 4, 2019 · Synced Oct 24, 2026, 2:43 AM EDT
Completed Phase 2 Interventional

Does Reducing Spasticity Permit an Increase in Strength?

NCT00255073
View directory record Official record
Conditions
Spastic Diplegic Cerebral Palsy
Interventions
baclofen
Drug
Lead sponsor
University of Southern California
Other
Eligibility
5 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 23, 2014 · Synced Oct 24, 2026, 2:43 AM EDT
Recruiting Not applicable Interventional

Little Cigar Oxidants

NCT06310187
View directory record Official record
Conditions
Tobacco Use, Oxidative Stress
Interventions
High Oxidant Little Cigar, Low Oxidant Little Cigar, Usual Cigarette
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Oct 24, 2026, 2:43 AM EDT
Completed Phase 2 Interventional

A Study of TAK-755 (rADAMTS13) With Little to No Plasma Exchange (PEX) Treatment in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura (iTTP)

NCT05714969
View directory record Official record
Conditions
Thrombotic Thrombocytopenic Purpura (TTP)
Interventions
TAK-755
Biological
Lead sponsor
Takeda
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
12
States / cities
Gainesville, Florida • Boston, Massachusetts • Minneapolis, Minnesota + 7 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 24, 2026, 2:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Little Cigar and Cigarillo Warnings to Reduce Tobacco-Related Cancers and Disease - Eye Tracking

NCT06546618
View directory record Official record
Conditions
Tobacco Use
Interventions
LCC pack stimuli images
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
21 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 24, 2026, 2:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Eye-Hand Coordination in Children With Spastic Diplegia

NCT00024791
View directory record Official record
Conditions
Diplegia, Spastic
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 24, 2026, 2:43 AM EDT
Terminated Not applicable Interventional

FES to Improve Gait in CP

NCT04591288
View directory record Official record
Conditions
Cerebral Palsy, Spastic Diplegia Cerebral Palsy, Gait
Interventions
Functional Electrical Stimulation protocol, Treadmill only protocol
Other
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
10 Years to 18 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Newark, Delaware • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Oct 24, 2026, 2:43 AM EDT