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Showing 1–24 of 557 matching trials from the live ClinicalTrials.gov search.
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Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Project Talk Trial: Engaging Underserved Communities in End-of-life Conversations

NCT04612738
Conditions
Advance Care Planning, Advance Directives, Terminal Illness, Chronic Illness, Communication
Interventions
Hello (serious game), The Conversation Project (CP) Starter Kit, Table Topics (general conversation game)
Behavioral · Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
79
States / cities
Athens, Alabama • Kingman, Arizona • Show Low, Arizona + 70 more
Recruiting Not applicable Interventional Accepts healthy volunteers

Language Processing and TMS

NCT05425615
Conditions
Stroke, Aphasia, Language
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2032
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Aphasia, Stroke
Interventions
Constraint Induced Language Therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Houston, Texas
Completed No phase listed Observational

Genetic Linkage Studies of Stuttering

NCT00001604
Conditions
Stuttering
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
6 Years and older
Enrollment
3,044 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Recruiting No phase listed Observational

Language in Primary Progressive Aphasia

NCT00537004
Conditions
Primary Progressive Aphasia
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Speech Sound Disorder
Interventions
AI-guided maintenance training with visual-acoustic biofeedback, Treatment as Usual (TAU)
Behavioral
Lead sponsor
New York University
Other
Eligibility
9 Years to 17 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
Bloomfield, New Jersey • Syracuse, New York
Recruiting Not applicable Interventional Accepts healthy volunteers

Speech-in-noise Perception in Autism and Fragile X

NCT06088589
Conditions
Autism Spectrum Disorder, Fragile X Syndrome
Interventions
Mismatch negativity
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
15 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Conditions
Speech Sound Disorder
Interventions
Speech Intervention
Behavioral
Lead sponsor
Philip Combiths
Other
Eligibility
3 Years to 8 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Completed No phase listed Observational Accepts healthy volunteers

Auditory Masking Effects on Speech Fluency in Aphasia and Apraxia of Speech

NCT02094014
Conditions
Apraxia of Speech, Aphasia, Cerebrovascular Accident
Interventions
Normal Auditory Feedback, Masked Auditory Feedback, Altered Auditory Feedback
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Recruiting Not applicable Interventional Accepts healthy volunteers

Transcranial Alternating Current Stimulation (tACS) in Aphasia

NCT04375722
Conditions
Aphasia, Stroke
Interventions
tACS
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2030
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Conditions
Parkinson's Disease
Interventions
Combined speech and exercise intervention, Health education
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 89 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Velopharyngeal Insufficiency, Velopharyngeal Incompetence Due to Cleft Palate, Inadequate Velopharyngeal Closure, Palatopharyngeal Incompetence, Hypernasality
Interventions
Expiratory Muscle Strength Training, Maintenance Training
Device
Lead sponsor
Noel Jabbour
Other
Eligibility
5 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Stroke and Aphasia
Interventions
Communal singing
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Stuttering, Adult
Interventions
Transcranial Magnetic Stimulation
Device
Lead sponsor
Kansas State University
Other
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Manhattan, Kansas
Completed Not applicable Interventional Results available

Treating Childhood Apraxia of Speech

NCT03238677
Conditions
Childhood Apraxia of Speech
Interventions
Speech Motor Chaining without Biofeedback, Biofeedback, Distributed Practice, Massed --> Distributed Practice
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
9 Years to 17 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Syracuse, New York
Completed Not applicable Interventional Results available

Comparison of Treatment for Hoarding Disorder

NCT02040805
Conditions
Hoarding Disorder
Interventions
Group Cognitive Behavioral Therapy, Peer Facilitated Support Group
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
323 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
San Francisco, California
Conditions
Presbycusis
Interventions
transcutaneous auricular vagus nerve stimulation, Sham Control
Device
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Down Syndrome
Interventions
Babble Boot Camp
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
0 Months to 12 Months
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tempe, Arizona
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Evaluation of the Nucleus 5 Cochlear Implant (CI) System

NCT01072409
Conditions
Hearing Loss
Interventions
Nucleus 5 Cochlear implant, Cochlear implantation
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed Not applicable Interventional Accepts healthy volunteers Results available

Internet-based Conversational Engagement Clinical Trial

NCT02871921
Conditions
Aging, Mild Cognitive Impairment
Interventions
Conversational Engagement
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
75 Years and older
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
2
States / cities
Boston, Massachusetts • Ann Arbor, Michigan
Conditions
Opioid Use Disorder
Interventions
Talk About It (conversation aid)
Behavioral
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Springfield, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Rare Diseases Clinical Research Network: Neurophysiological Correlates

NCT03077308
Conditions
Rett Syndrome, Preserved Speech Variant, Mecp2 Duplication Syndrome, Rett-related Disorders
Interventions
Auditory and Visual Event-related Potentials and EEG
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
2 Years to 65 Years
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
5
States / cities
Denver, Colorado • Boston, Massachusetts • Cincinnati, Ohio + 2 more
Conditions
Parkinson Disease
Interventions
Parkinson's Application, Digital Placebo Application
Device
Lead sponsor
Beats Medical
Industry
Eligibility
30 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Norfolk, Virginia
Withdrawn Phase 1 Interventional Accepts healthy volunteers

The Effects of Tactile Speech Feedback on Stuttering Frequency

NCT01315730
Conditions
Stuttering
Interventions
Tactile Stimulation
Device
Lead sponsor
University of Mississippi, Oxford
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2011
U.S. locations
1
States / cities
University, Mississippi