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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:06 PM EDT

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Showing 1–24 of 341 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Spinal Surgery Clear all
Not yet recruiting Phase 1Phase 2 Interventional

Stimulation-based Therapy to Improve Balance in DCM

NCT07298460
View directory record Official record
Conditions
Degenerative Cervical Myelopathy
Interventions
Transcutaneous spinal cord stimulation, Balance and Gait Training
Device · Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
50 Years to 90 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 23, 2025 · Synced Oct 21, 2026, 4:06 PM EDT
Terminated Phase 4 Interventional Results available

Erector Spinae Block for Spine Surgery

NCT05417113
View directory record Official record
Conditions
Lumbar Radiculopathy
Interventions
Liposomal bupivacaine, Bupivacaine
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 85 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 29, 2024 · Synced Oct 21, 2026, 4:06 PM EDT
Completed No phase listed Observational

Intraocular Pressure During Spine Surgery

NCT00593359
View directory record Official record
Conditions
Intraocular Pressure
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Oct 21, 2026, 4:06 PM EDT
Terminated No phase listed Observational

Single Position Spine Surgery Registry

NCT04839783
View directory record Official record
Conditions
Spine Fusion, Spinal Stenosis, Degenerative Disc Disease
Interventions
Not listed
Lead sponsor
Spine and Scoliosis Research Associates
Other
Eligibility
18 Years to 100 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
5
States / cities
Boston, Massachusetts • New York, New York • Wilmington, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 21, 2026, 4:06 PM EDT
Completed No phase listed Observational

Comparison of Antibiotic Protocols in Spine Patients With Postoperative Drains

NCT01608854
View directory record Official record
Conditions
Surgical Wound Infection, Spinal Deformity, Spinal Degeneration
Interventions
Antibiotic Protocol
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
539 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2016 · Synced Oct 21, 2026, 4:06 PM EDT
Recruiting Phase 2Phase 3 Interventional

Tranexamic Acid to Reduce Blood Loss in Spine Surgery

NCT02314988
View directory record Official record
Conditions
Spinal Injuries, Spinal Deformity
Interventions
Tranexamic Acid, Placebo
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
4
States / cities
San Francisco, California • Louisville, Kentucky • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 21, 2026, 4:06 PM EDT
Recruiting No phase listed Observational

Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure

NCT05648474
View directory record Official record
Conditions
Intervertebral Disc Degeneration, Stenosis, Spinal, Spondylolisthesis, Spinal Deformity, Spinal Instability
Interventions
Somatosensory evoked potential [SSEP] intraoperative monitoring
Diagnostic Test
Lead sponsor
Alphatec Spine, Inc.
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Carlsbad, California
Source: ClinicalTrials.gov public record
Updated Oct 24, 2024 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Phase 3 Interventional Results available

An Implantable Spinal Cord Stimulation Pain Management System

NCT00205855
View directory record Official record
Conditions
Chronic Pain, Pain, Intractable, Pain, Back Pain, Failed Back Surgery Syndrome
Interventions
Precision SCS
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
9
States / cities
Huntsville, Alabama • Los Angeles, California • San Francisco, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2012 · Synced Oct 21, 2026, 4:06 PM EDT
Enrolling by invitation Not applicable Interventional

Essential Amino Acid Supplementation in Adult Spinal Deformity Patients

NCT07341399
View directory record Official record
Conditions
Adult Spinal Deformity
Interventions
Essential Amino Acid Supplement by Amino Co, Placebo
Dietary Supplement
Lead sponsor
University of Arkansas
Other
Eligibility
40 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 21, 2026, 4:06 PM EDT
Recruiting Not applicable Interventional

Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery

NCT07218133
View directory record Official record
Conditions
Spinal Fusion, Hyperglycemia, Postoperative Pain Management, Postoperative Care, Spine Disease, Neurologic Deficits, Neurological Disorder, Inflammation, Spine Condition, Spinal (Fusion) Surgery, Cytokine Levels, Spine Fusion
Interventions
Auricular vagus nerve stimulation, Sham Auricular Vagus nerve Stimulation
Device
Lead sponsor
Alexander T. Yahanda
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Not applicable Interventional

Coping After Pediatric Scoliosis Surgery

NCT04063670
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Video Intervention, Control
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
11 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Oct 21, 2026, 4:06 PM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Effect of RECK in Posterior Spinal Fusion

NCT06447194
View directory record Official record
Conditions
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Disease
Interventions
Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail, Placebo
Drug · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Oct 21, 2026, 4:06 PM EDT
Not listed No phase listed Observational

Prospective Study of Safety and Efficacy of InQu® Bone Graft Extender in Lumbar Interbody Fusion Surgery

NCT02400762
View directory record Official record
Conditions
Intervertebral Disc Degeneration
Interventions
Not listed
Lead sponsor
ISTO Technologies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
2
States / cities
Los Angeles, California • Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Oct 21, 2026, 4:06 PM EDT
Completed No phase listed Observational

Surgical Versus Nonoperative Treatment of Metastatic Epidural Spinal Cord Compression

NCT00634426
View directory record Official record
Conditions
Metastatic Epidural Spinal Cord Compression
Interventions
Surgical excision of the metastatic process, Radiotherapy of the metastatic spine process
Procedure · Radiation
Lead sponsor
AOSpine North America Research Network
Network
Eligibility
18 Years and older
Enrollment
163 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
7
States / cities
Kansas City, Kansas • Baltimore, Maryland • Rochester, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated May 21, 2015 · Synced Oct 21, 2026, 4:06 PM EDT
Not listed Not applicable Interventional

Massage Therapy After Thoracic or Lumbar Surgery

NCT06424158
View directory record Official record
Conditions
Scoliosis; Adolescence, Adolescent Idiopathic Scoliosis, Thoracic Region, Adolescent Idiopathic Scoliosis, Lumbar Region
Interventions
Massage Therapy
Other
Lead sponsor
Cook Children's Health Care System
Other
Eligibility
7 Years to 19 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 23, 2024 · Synced Oct 21, 2026, 4:06 PM EDT
Terminated Phase 2 Interventional

Safety and Efficacy of Pre-incisional Intravenous Ibuprofen to Reduce Postoperative Pain and Opioid Dependence After Posterior Cervical or Lumbar Instrumented Spine Surgery

NCT02276911
View directory record Official record
Conditions
Cervical Spondylosis, Lumbar Spondylosis
Interventions
Ibuprofen, normal saline
Drug · Other
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 19, 2024 · Synced Oct 21, 2026, 4:06 PM EDT
Completed Phase 2 Interventional Results available

The Darbepoetin Alfa for Ischemic Surgical Complications (DISC) Dose Finding Trial

NCT00647998
View directory record Official record
Conditions
Spinal Ischemia, Stroke, Neuroprotection
Interventions
Darbepoetin alfa, Standard care
Drug · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 100 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 5, 2017 · Synced Oct 21, 2026, 4:06 PM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery

NCT06096181
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Multimodal Analgesia, Opioid Induced Hyperalgesia, Remifentanil, Dexmedetomidine, Posterior Spinal Fusion
Interventions
Remifentanil TIVA, Dexmedetomidine TIVA, Propofol TIVA
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 21, 2026, 4:06 PM EDT
Withdrawn Not applicable Interventional

A Prospective Trial for the Effectiveness of the Use of Spinal Cord Stimulation (SCS) in Failed Knee Surgery

NCT01912924
View directory record Official record
Conditions
Chronic Pain
Interventions
Spinal cord stimulator (Boston Scientific)
Device
Lead sponsor
Coastal Orthopedics & Sports Medicine
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Jul 31, 2013 · Synced Oct 21, 2026, 4:06 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Yoga for Adolescent Idiopathic Scoliosis (AIS) Patients

NCT06003010
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Spinal Fusion
Interventions
Yoga
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
10 Years to 18 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 1, 2023 · Synced Oct 21, 2026, 4:06 PM EDT
Terminated Phase 4 Interventional Results available

The Effects of Dexmedetomidine Dose on Motor Evoked Potentials

NCT03378973
View directory record Official record
Conditions
Spinal Fusion
Interventions
Dexmedetomidine
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 28, 2020 · Synced Oct 21, 2026, 4:06 PM EDT
Enrolling by invitation No phase listed Observational

Advanced Materials Science in XLIF Study

NCT03649490
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis
Interventions
Not listed
Lead sponsor
NuVasive
Industry
Eligibility
18 Years to 80 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
15
States / cities
Hartford, Connecticut • Jacksonville, Florida • Tampa, Florida + 12 more
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 21, 2026, 4:06 PM EDT
Completed No phase listed Observational

Use of Radiostereometric Analysis (RSA) Following Spinal Fusion Versus the DYNESYS Stabilization System

NCT00152165
View directory record Official record
Conditions
Spinal Fusion, Orthopedic Procedures
Interventions
Radiostereometric Analysis beads inserted during surgery
Procedure
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 2, 2008 · Synced Oct 21, 2026, 4:06 PM EDT
Terminated No phase listed Observational

Motor Evoked Potentials and SedLine

NCT00805844
View directory record Official record
Conditions
Spine Surgery
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 15, 2011 · Synced Oct 21, 2026, 4:06 PM EDT