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ClinicalTrials.gov public records Last synced Oct 20, 2026, 1:52 PM EDT

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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Status Asthmaticus Clear all
Completed Not applicable Interventional Results available

Effectiveness of the Aeroneb in Acute Severe Asthma

NCT03029156
View directory record Official record
Conditions
Asthma Exacerbation
Interventions
Aeroneb nebulizer, Small volume jet nebulizer
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 20, 2026, 1:52 PM EDT
Completed Phase 2 Interventional

Treating Exacerbations of Asthma With Oral Montelukast in Children

NCT05819541
View directory record Official record
Conditions
Status Asthmaticus
Interventions
Montelukast Oral Granules, Albuterol, Corticosteroid
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
4 Years to 12 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 20, 2026, 1:52 PM EDT
Completed Not applicable Interventional

Effectiveness and Cost Study Comparing Two Ways to Deliver Albuterol for the Treatment of Asthma in the Hospital

NCT00623688
View directory record Official record
Conditions
Status Asthmaticus
Interventions
Metered Dose Inhaler & Optichamber Advantage Valve Holding Chamber (VHC), Airlife Sidestream High Efficiency Nebulizer
Device
Lead sponsor
Akron Children's Hospital
Other
Eligibility
12 Months to 18 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 14, 2015 · Synced Oct 20, 2026, 1:52 PM EDT
Completed Phase 4 Interventional Results available

Ideal Steroids for Asthma Treatment in the PICU

NCT03900624
View directory record Official record
Conditions
Asthma Childhood
Interventions
Dexamethasone
Drug
Lead sponsor
Johns Hopkins All Children's Hospital
Other
Eligibility
5 Years to 17 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Feb 23, 2024 · Synced Oct 20, 2026, 1:52 PM EDT
Terminated Phase 2 Interventional Results available

Heliox-Powered Albuterol Therapy in the Treatment of Children Admitted With Acute Asthma Exacerbation

NCT00410150
View directory record Official record
Conditions
Status Asthmaticus
Interventions
Helium-oxygen-driven albuterol nebulizer, Oxygen
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
24 Months to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 8, 2010 · Synced Oct 20, 2026, 1:52 PM EDT
Completed Phase 4 Interventional

Trial of Terbutaline for the Treatment of Status Asthmaticus in Children

NCT00124995
View directory record Official record
Conditions
Status Asthmaticus
Interventions
terbutaline
Drug
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
Up to 18 Years
Enrollment
40 participants
Timeline
2003 – 2006
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2013 · Synced Oct 20, 2026, 1:52 PM EDT
Not listed No phase listed Observational

Intravenous Terbutaline in Severe Status Asthmaticus

NCT00750568
View directory record Official record
Conditions
Status Asthmaticus
Interventions
Not listed
Lead sponsor
Wayne State University
Other
Eligibility
2 Years to 18 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
3
States / cities
Louisville, Kentucky • Detroit, Michigan • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2008 · Synced Oct 20, 2026, 1:52 PM EDT
Completed No phase listed Observational

Pleth Variability and Asthma Severity in Children

NCT02302261
View directory record Official record
Conditions
Status Asthmaticus
Interventions
Not listed
Lead sponsor
Northwell Health
Other
Eligibility
Up to 17 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Jul 26, 2016 · Synced Oct 20, 2026, 1:52 PM EDT
Terminated Phase 2 Interventional Results available

Study Evaluating the Safety and Effects of MN-221 in Subjects Experiencing an Acute Exacerbation of Asthma

NCT00683449
View directory record Official record
Conditions
Asthma, Status Asthmaticus
Interventions
Dose Group 1, MN-221 placebo, Dose Group 2, Dose Group 3
Drug
Lead sponsor
MediciNova
Industry
Eligibility
18 Years to 55 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
9
States / cities
Phoenix, Arizona • Los Angeles, California • Sylmar, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2011 · Synced Oct 20, 2026, 1:52 PM EDT
Recruiting Phase 2 Interventional

Pediatric Asthma Trial of Corticosteroid Heterogeneity (PATCH): Trial of Dexamethasone Versus Methylprednisolone for Pediatric Critical Asthma

NCT07455396
View directory record Official record
Conditions
Asthma (Diagnosis)
Interventions
Dexamethasone (0.6mg/kg; Max 16mg) Once Daily, Dexamethasone (0.25 mg/kg/dose, Max dose 16mg) every 6-hours, Methylprednisolone
Drug
Lead sponsor
Johns Hopkins All Children's Hospital
Other
Eligibility
3 Years to 17 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 20, 2026, 1:52 PM EDT
Withdrawn Phase 2 Interventional

Non Invasive Positive Pressure Ventilation in Status Asthmaticus

NCT01403428
View directory record Official record
Conditions
Status Asthmaticus
Interventions
Noninvasive positive pressure ventilation
Other
Lead sponsor
Southern Illinois University
Other
Eligibility
1 Year to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Springfield, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 12, 2014 · Synced Oct 20, 2026, 1:52 PM EDT
Completed Phase 4 Interventional Results available

Continuous Levalbuterol for Treatment of Status Asthmaticus in Children

NCT00124176
View directory record Official record
Conditions
Asthma
Interventions
Racemic albuterol (R+S albuterol), Levalbuterol (R albuterol)
Drug
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Years to 18 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 14, 2013 · Synced Oct 20, 2026, 1:52 PM EDT
Not listed Phase 2Phase 3 Interventional

Montelukast With Status Asthmaticus, Ages 6-18

NCT00494572
View directory record Official record
Conditions
Status Asthmaticus, Asthma
Interventions
Montelukast, sterile water
Drug · Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
6 Years to 18 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 16, 2008 · Synced Oct 20, 2026, 1:52 PM EDT
Withdrawn Not applicable Interventional

NiPPV in the Treatment of Acute Asthma Exacerbations

NCT03219736
View directory record Official record
Conditions
Bronchial Asthma, Status Asthmaticus
Interventions
Standard of Care therapies, NiPPV Therapy, Routine Respiratory Care
Procedure · Device
Lead sponsor
Arkansas Children's Hospital Research Institute
Other
Eligibility
2 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Feb 22, 2023 · Synced Oct 20, 2026, 1:52 PM EDT
Terminated Phase 4 Interventional

Steroids in Children Hospitalized With Asthma

NCT02780479
View directory record Official record
Conditions
Asthma, Status Asthmaticus, Wheezes
Interventions
Dexamethasone, Prednisone
Drug
Lead sponsor
University of Florida
Other
Eligibility
2 Years to 18 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 21, 2019 · Synced Oct 20, 2026, 1:52 PM EDT
Completed Phase 1 Interventional

Phase I, Placebo-Controlled, Blinded Pilot Study of Ipratropium in Children Admitted to the ICU With Status Asthmaticus

NCT02872597
View directory record Official record
Conditions
Status Asthmaticus
Interventions
Ipratropium, 0.9% Sodium Chloride, Albuterol, corticosteroids
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
2 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 20, 2026, 1:52 PM EDT
Completed No phase listed Observational

B2-Adrenergic Receptor Polymorphisms

NCT00279786
View directory record Official record
Conditions
Status Asthmaticus
Interventions
Blood draw
Procedure
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
2 Years to 18 Years
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 30, 2023 · Synced Oct 20, 2026, 1:52 PM EDT
Terminated Phase 4 Interventional Results available

Comparison of Albuterol for Status Asthmaticus

NCT02966184
View directory record Official record
Conditions
Status Asthmaticus
Interventions
preservative free albuterol
Drug
Lead sponsor
Norton Healthcare
Other
Eligibility
5 Years to 17 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated May 20, 2021 · Synced Oct 20, 2026, 1:52 PM EDT
Completed Not applicable Interventional Results available

HFCWO in Hospitalized Asthmatic Children

NCT00722020
View directory record Official record
Conditions
Bronchial Asthma, Asthma, Status Asthmaticus
Interventions
VEST
Device
Lead sponsor
Hill-Rom
Industry
Eligibility
18 Months to 18 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
2
States / cities
Long Island City, New York
Source: ClinicalTrials.gov public record
Updated Aug 7, 2017 · Synced Oct 20, 2026, 1:52 PM EDT
Completed Phase 4 Interventional Results available

Intramuscular Epinephrine as an Adjunctive Treatment for Severe Pediatric Asthma Exacerbation

NCT01705964
View directory record Official record
Conditions
Asthma
Interventions
IM epinephrine 1:1000, No intervention
Drug · Other
Lead sponsor
University of Louisville
Other
Eligibility
6 Years to 17 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jul 6, 2021 · Synced Oct 20, 2026, 1:52 PM EDT
Not listed Phase 2Phase 3 Interventional

Montelukast With Status Asthmaticus, Ages 2-5

NCT00491790
View directory record Official record
Conditions
Status Asthmaticus, Asthma
Interventions
Montelukast, Sterile water
Drug · Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
2 Years to 5 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 16, 2008 · Synced Oct 20, 2026, 1:52 PM EDT
Terminated Phase 1Phase 2 Interventional

Randomized, Placebo/Active Crossover Dose-ranging Study for Safety and Efficacy in Asthma Patients.

NCT01025648
View directory record Official record
Conditions
Asthma
Interventions
E004 (epinephrine inhalation aerosol), 90 mcg/actuation, E004 Placebo, E004 (epinephrine inhalation aerosol), 125 mcg, E004 (epinephrine inhalation aerosol), 220 mcg, epinephrine inhalation aerosol, CFC propelled, E004 (epinephrine inhalation aerosol), 160 mcg
Drug
Lead sponsor
Amphastar Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
2
States / cities
San Jose, California • Stockton, California
Source: ClinicalTrials.gov public record
Updated May 16, 2018 · Synced Oct 20, 2026, 1:52 PM EDT
Terminated Not applicable Interventional Results available

Use of High Frequency Chest Compression in Pediatric Status Asthmaticus

NCT00552448
View directory record Official record
Conditions
Pediatric, Asthma, Acute Exacerbation, Pediatric ICU
Interventions
High Frequency Chest Compression VEST
Device
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
2 Years to 21 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
3
States / cities
Stony Brook, New York • Spartanburg, South Carolina • Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Sep 14, 2016 · Synced Oct 20, 2026, 1:52 PM EDT
Completed No phase listed Observational

Steroid Metabolism in Obese and Non-Obese Pediatric Patients Hospitalized for Status Asthmaticus

NCT04874610
View directory record Official record
Conditions
Pediatric Obesity, Asthma in Children
Interventions
Methylprednisolone
Drug
Lead sponsor
Duke University
Other
Eligibility
2 Years to 20 Years
Enrollment
15 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 1, 2022 · Synced Oct 20, 2026, 1:52 PM EDT