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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Stress Physiology Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Endothelin Receptor Function and Acute Stress

NCT02116335
View directory record Official record
Conditions
Hypertension
Interventions
Bosentan, Placebo
Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 50 Years
Enrollment
320 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Jul 23, 2026, 2:08 AM EDT
Withdrawn Phase 1Phase 2 Interventional Accepts healthy volunteers

Assessment of Corneal Endothelial Function Following Hypoxic Stress

NCT04175938
View directory record Official record
Conditions
Fuchs' Endothelial Corneal Dystrophy
Interventions
Wearing of contact lens
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 1, 2026 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effect of Aspirin on Hemostatic and Vascular Function After Live Fire Fighting

NCT01276691
View directory record Official record
Conditions
Cardiovascular Risk Factor, C.Medical Procedure; Vascular, Functional or Late, Electrolyte and Fluid Balance Conditions
Interventions
81 mg enteric coated aspirin
Drug
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
40 Years to 60 Years · Male only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Champaign, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 20, 2020 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Risk of Oxygen During Cardiac Surgery Trial

NCT02361944
View directory record Official record
Conditions
Cardiac Surgery
Interventions
Oxygen - normoxia, Oxygen - hyperoxia
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Not applicable Interventional

Effects of Almonds On Endothelial Function In Patients With Coronary Artery Disease

NCT01038362
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
NCEP Step 1 diet plus Almonds, No Almonds
Other
Lead sponsor
Boston University
Other
Eligibility
21 Years to 80 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 22, 2009 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Teenage Health and Wellness Study

NCT03989934
View directory record Official record
Conditions
Stress, Externalizing Symptoms, Depression Symptoms, Anxiety
Interventions
The Mind in Action, Healthy Topics
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
13 Years to 16 Years
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 9, 2023 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Blueberries, Bananas, Exercise Recovery

NCT03445234
View directory record Official record
Conditions
Inflammatory Response, Metabolic Disturbance, Immune Suppression
Interventions
Blueberry, Placebo, banana, No banana
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 25, 2018 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mindfulness, Emotional Well-being, and Sleep Quality

NCT00887614
View directory record Official record
Conditions
Stress, Psychological, Sleep
Interventions
Mindfulness-Based Stress Reduction (MBSR)
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
372 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 3, 2011 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Not applicable Interventional

Efficacy of Automated Text Messaging Services

NCT05621265
View directory record Official record
Conditions
Sleep, Physical Therapy
Interventions
Automated Text messaging
Behavioral
Lead sponsor
Black Hills State University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Spearfish, South Dakota
Source: ClinicalTrials.gov public record
Updated Nov 20, 2022 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Not applicable Interventional

Effects of Dietary Supplement Tauroursodeoxycholic Acid on Vascular Function

NCT03331432
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Tauroursodeoxycholic acid, Placebo
Dietary Supplement
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
20 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 18, 2018 · Synced Jul 23, 2026, 2:08 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Role of NADPH Oxidase in Microvascular Dysfunction Following GDM

NCT05946798
View directory record Official record
Conditions
Gestational Diabetes, Oxidative Stress, Vascular Endothelial Function
Interventions
Acetylcholine, Insulin aspart
Drug
Lead sponsor
Anna Stanhewicz, PhD
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 12, 2025 · Synced Jul 23, 2026, 2:08 AM EDT
Active, not recruiting No phase listed Observational

A Study to Evaluate Homocysteine Metabolism and Endothelial Function in ADPKD

NCT05193981
View directory record Official record
Conditions
Autosomal Dominant Polycystic Kidney Disease
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
15 Years to 40 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vasoprotective Activities of Low-Fat Milk in Individuals With Metabolic Syndrome

NCT01411293
View directory record Official record
Conditions
Cardiovascular Disease, Metabolic Syndrome, Obesity
Interventions
Low-Fat Milk, Rice Milk
Other
Lead sponsor
University of Connecticut
Other
Eligibility
18 Years to 50 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 5, 2014 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nitrate and Vitamin C on Vascular Health Oxidative Stress

NCT04283630
View directory record Official record
Conditions
Endothelial Dysfunction
Interventions
Dietary nitrate in the form of beetroot juice for all participnats, Nature Made vitamin c 1000 mg, Placebo
Dietary Supplement
Lead sponsor
David Travis Thomas
Other
Eligibility
50 Years to 70 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
2
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Phase 2 Interventional

Biomechanical Effects of Duloxetine on Bladder and Sphincter Muscle Function in Women in Pure Genuine Stress Incontinence

NCT00190567
View directory record Official record
Conditions
Urinary Stress Incontinence
Interventions
duloxetine, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 25, 2007 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

E-cigarettes and Blood Vessel Function

NCT02740595
View directory record Official record
Conditions
Nicotine Dependence
Interventions
one time exposure to e-cig with nicotine, one time exposure to e-cig without nicotine, one time exposure to empty e-cig
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
21 Years to 45 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Jul 23, 2026, 2:08 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Mindfulness in a College Physiology Course

NCT06423053
View directory record Official record
Conditions
Mindfulness, Stress, Well-being
Interventions
Biology Course with Integrated Mindfulness
Behavioral
Lead sponsor
Trustees of Dartmouth College
Other
Eligibility
18 Years and older
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Hanover, New Hampshire
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Relora Supplement on Anxiety, Cognitive Performance & Mood Tested After Induced Stress

NCT02734251
View directory record Official record
Conditions
Mood (Psychological Function)
Interventions
Relora, Placebo
Dietary Supplement
Lead sponsor
InterHealth Nutraceuticals, Inc.
Industry
Eligibility
21 Years to 59 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2016
U.S. locations
1
States / cities
Boca Raton, Florida
Source: ClinicalTrials.gov public record
Updated May 23, 2016 · Synced Jul 23, 2026, 2:08 AM EDT
Withdrawn Phase 4 Interventional

Pilot Study Evaluating Stress Response and Immune Function in Mechanically Ventilated Patients With Alcohol Use Disorders Treated With Propofol or Midazolam

NCT00871039
View directory record Official record
Conditions
Alcoholism, Respiration, Artificial
Interventions
Propofol, Midazolam
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
2
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 29, 2016 · Synced Jul 23, 2026, 2:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Microalgae Extract Dietary Supplement on Gut Health, Anxiety, and Immune Function

NCT06425094
View directory record Official record
Conditions
Gastrointestinal Problem, Anxiety, Stress, Gastrointestinal Symptoms
Interventions
Microalgae Extract Capsules, Placebo
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 55 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jul 23, 2026, 2:08 AM EDT
Recruiting Not applicable Interventional

Impact of Cognitive Behavioral Therapy on PTSD-CVD Link

NCT06429293
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Cognitive processing therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 24, 2025 · Synced Jul 23, 2026, 2:08 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Understanding Dose Related Effects of Strawberry

NCT06173765
View directory record Official record
Conditions
Pre-diabetes, Insulin Sensitivity, Insulin Resistance, Inflammation
Interventions
freeze-dried whole strawberry powder 36 g powder, freeze-dried whole strawberry powder 12 g, freeze-dried control powder 0 g strawberry
Other
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
20 Years to 60 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Jul 23, 2026, 2:08 AM EDT
Recruiting Not applicable Interventional

Mechanisms of Depression and Anhedonia in Adolescents: Linking Sleep to Reward- and Stress-Related Brain Function

NCT05691439
View directory record Official record
Conditions
Depression in Adolescence
Interventions
Sleep extension and advance, Regular sleep duration and timing
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
14 Years to 18 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 16, 2025 · Synced Jul 23, 2026, 2:08 AM EDT
Not yet recruiting Phase 2 Interventional

Remotely Administered tDCS to Improve Cognitive Function in Veterans With mTBI and PTSD Principal Investigator

NCT07414537
View directory record Official record
Conditions
Cognition, Brain Injuries, Stress Disorders, Post-Traumatic
Interventions
Transcranial direct current stimulation (tDCS), Cognitive training
Device · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 75 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jul 23, 2026, 2:08 AM EDT