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ClinicalTrials.gov public records Last synced May 22, 2026, 3:48 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Substance Abuse Disorders Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Opioid Use Disorder, Chronic Back Pain, Anxiety
Interventions
low intensity focused ultrasound (LIFU)
Device
Lead sponsor
Washington D.C. Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced May 22, 2026, 3:48 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Opioid-use Disorder, Substance Use Disorders
Interventions
Exablate Model 4000 Type 2.0/2.1
Device
Lead sponsor
InSightec
Industry
Eligibility
18 Years to 60 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
4
States / cities
Tampa, Florida • Baltimore, Maryland • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced May 22, 2026, 3:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Substance-Related Disorders, Drug Addiction, Substance Abuse
Interventions
Home-Based Intervention, Educational Group
Behavioral
Lead sponsor
Treatment Research Institute
Other
Eligibility
12 Years to 19 Years
Enrollment
286 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 27, 2023 · Synced May 22, 2026, 3:48 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Alcohol Abuse, Substance Abuse, Post Traumatic Stress Disorder
Interventions
self-guided mHealth app only, self-guided mHealth app + 'real-time' feedback
Behavioral
Lead sponsor
UConn Health
Other
Eligibility
18 Years to 29 Years · Male only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced May 22, 2026, 3:48 AM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Cannabis Dependence
Interventions
quetiapine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 23, 2019 · Synced May 22, 2026, 3:48 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers
View directory record Official record
Conditions
Asthma, Tobacco Use
Interventions
Not listed
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years to 35 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 8, 2013 · Synced May 22, 2026, 3:48 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Post Traumatic Stress Disorder (PTSD), Addiction, Alcohol Abuse
Interventions
N-Acetylcysteine (NAC) Treatment, Cognitive Behavioral Therapy (CBT), Inactive Placebo Oral Capsule, Functional magnetic resonance imaging (fMRI), Proton magnetic resonance spectroscopy (MRS) Imaging
Drug · Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 70 Years
Enrollment
182 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
2
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced May 22, 2026, 3:48 AM EDT
Active, not recruiting Phase 1 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
Interventions
Active Dronabinol, Placebo, Active Ethanol
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced May 22, 2026, 3:48 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Drug Addiction
Interventions
Zolpidem extended-release, MET/CBT
Drug · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years
Enrollment
127 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 21, 2019 · Synced May 22, 2026, 3:48 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Cocaine-Related Disorders
Interventions
Baclofen
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1997
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2016 · Synced May 22, 2026, 3:48 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Drug Abuse, HIV Infections
Interventions
Injection and Non-Injection Drug Users
Other
Lead sponsor
The City College of New York
Other
Eligibility
15 Years to 50 Years
Enrollment
836 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 1, 2016 · Synced May 22, 2026, 3:48 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Substance Use, Sexual Risk Behaviors
Interventions
Risk Reduction Therapy for Adolescents, Usual services
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
12 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 3, 2016 · Synced May 22, 2026, 3:48 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Opioid-use Disorder, Opioid Use, Opioid Dependence, Opioid Abuse, Medication Assisted Treatment, Infusion Catheter, Wound, Lidopatch, Ambu ACTion, Pregnancy Related, Cesarean Section
Interventions
Lidocaine patch, Ambu ACTion pump, 0.125% bupivacaine at 8cc/hr
Drug · Device
Lead sponsor
WellSpan Health
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 6, 2021 · Synced May 22, 2026, 3:48 AM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Substance Use
Interventions
Mantente REAL
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
10 Years to 17 Years
Enrollment
5,524 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 14, 2021 · Synced May 22, 2026, 3:48 AM EDT
Completed Phase 2Phase 3 Interventional Results available
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Buprenorphine + Naltrexone, Placebo + Naltrexone
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
11
States / cities
Los Angeles, California • San Francisco, California • Denver, Colorado + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced May 22, 2026, 3:48 AM EDT
Completed Phase 1 Interventional
View directory record Official record
Conditions
Cocaine-Related Disorders
Interventions
Cocaine
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
21 Years to 45 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2001
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced May 22, 2026, 3:48 AM EDT
Terminated Phase 4 Interventional Results available
View directory record Official record
Conditions
Alcohol Use Disorder, Substance Use, Alcohol Abuse or Dependence
Interventions
Vivitrol (Extended Release Naltrexone)
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years and older
Enrollment
179 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced May 22, 2026, 3:48 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Alcohol Drinking, Marijuana
Interventions
Text Messaging and Brief Negotiation Interview
Behavioral
Lead sponsor
Yale University
Other
Eligibility
13 Years to 18 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 22, 2018 · Synced May 22, 2026, 3:48 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Cocaine Dependence, Opioid Dependency
Interventions
Disulfiram, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 45 Years
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced May 22, 2026, 3:48 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Arthropathy of Knee, Post Operative Pain, Opioid Use, Opioid Abuse, Opioid Misuse
Interventions
Opioid education in person, Opioid education via video
Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 80 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced May 22, 2026, 3:48 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Child Abuse, Child Neglect, Risk Behavior, Delinquency, Mental Health Impairment, Substance Use, Educational Problems, Adolescent Development, Adolescent Behavior, Sexual Behavior, Child Maltreatment
Interventions
FHF-T
Behavioral
Lead sponsor
University of Denver
Other
Eligibility
13 Years to 16 Years
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2044
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced May 22, 2026, 3:48 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Drug Abuse
Interventions
WIDUS computer-delivered, indirect brief intervention, Nutrition time control/placebo intervention
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 7, 2015 · Synced May 22, 2026, 3:48 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
Suicidal Ideation, Depression, Alcohol Abuse
Interventions
Intranasal ketamine, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
21 Years to 60 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced May 22, 2026, 3:48 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available
View directory record Official record
Conditions
Substance Use Disorders
Interventions
DARTNA, Treatment-As-Usual
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2018 · Synced May 22, 2026, 3:48 AM EDT