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ClinicalTrials.gov public records Last synced May 22, 2026, 3:50 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Substance Use Disorder (SUD) Clear all
Withdrawn Phase 4 Interventional
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Substance Use Disorder
Interventions
Atomoxetine, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
15 Years to 30 Years
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 4, 2013 · Synced May 22, 2026, 3:50 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Cocaine Use Disorder, Cocaine Dependence, Substance Use Disorder (SUD)
Interventions
Transcranial Direct Current Stimulator (tDCS), Cognitive Reappraisal Training
Device · Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 60 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced May 22, 2026, 3:50 AM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Alcohol Use Disorders
Interventions
doxazosin, placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 12, 2021 · Synced May 22, 2026, 3:50 AM EDT
Completed Phase 3 Interventional Results available
View directory record Official record
Conditions
ADHD, Substance Abuse
Interventions
Methylphenidate (OROS-MPH), Methylphenidate (OROS-MPH) - Placebo
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
13 Years to 18 Years
Enrollment
303 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
12
States / cities
Denver, Colorado • Jacksonville, Florida • St. Petersburg, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 6, 2013 · Synced May 22, 2026, 3:50 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
PTSD - Post Traumatic Stress Disorder, PTSD and Alcohol Use Disorder, PTSD and Trauma-related Symptoms, Substance Use Disorder (SUD), Depression, Mental Health, Trauma, Trauma Exposure, Traumatic Stress Disorder, Traumatic Stress, Post Traumatic Stress Symptoms
Interventions
Group Cognitive Processing Therapy (CPT), Control Group Individual trauma focused self-help via workbook
Behavioral
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
640 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
6
States / cities
Little Rock, Arkansas • Osceola, Arkansas • Texarkana, Arkansas + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced May 22, 2026, 3:50 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Substance Use Disorder (SUD), Mental Health Disorder, Criminal Recidivism
Interventions
reentry assistance mobile health app
Behavioral
Lead sponsor
Meaningful Measurement, Inc
Industry
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced May 22, 2026, 3:50 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Internalizing Disorders, Substance Use Disorders
Interventions
Family Support Protocol for Adolescent Internalizing Disorders (Fam-AID)
Behavioral
Lead sponsor
The National Center on Addiction and Substance Abuse at Columbia University
Other
Eligibility
13 Years to 21 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
4
States / cities
Jacksonville, Florida • Chicago, Illinois • Indianapolis, Indiana + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced May 22, 2026, 3:50 AM EDT
Not yet recruiting Not applicable Interventional
View directory record Official record
Conditions
Bipolar Disorder, Substance Use (Drugs, Alcohol)
Interventions
Senyo Health App
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced May 22, 2026, 3:50 AM EDT
Not yet recruiting Not applicable Interventional
View directory record Official record
Conditions
Substance Use Disorder (SUD)
Interventions
Community Restitution Apprenticeship-Focused Training (CRAFT), Standard Employment Model
Other
Lead sponsor
West Virginia School of Osteopathic Medicine
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Lewisburg, West Virginia
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced May 22, 2026, 3:50 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Substance Use Disorder
Interventions
Mindful Awareness in Body-oriented Therapy, Womens Health Education
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
217 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 11, 2018 · Synced May 22, 2026, 3:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
HIV Prevention, Sexually Transmitted Infections (STI), Preexposure Prophylaxis (PrEP), Incarceration, Hepatitis C Virus (HCV), Substance Use Disorder (SUD)
Interventions
Mobile Enhanced Prevention Support (MEPS), Control
Behavioral · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 59 Years · Male only
Enrollment
318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
3
States / cities
Oakland, California • Riverside, California
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced May 22, 2026, 3:50 AM EDT
Recruiting Early Phase 1 Interventional
View directory record Official record
Conditions
Substance Use Disorder (SUD)
Interventions
Regional Anesthesia, Hydromorphone Patient Controlled Analgelsic, Epidural local anesthetic infusion
Drug · Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced May 22, 2026, 3:50 AM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Nicotine, behavioral counseling for smoking cessation
Drug · Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 75 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 27, 2021 · Synced May 22, 2026, 3:50 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Substance Use Disorder (SUD), Opioid Use Disorder (OUD)
Interventions
Deep Brain Stimulation
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
22 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced May 22, 2026, 3:50 AM EDT
Not yet recruiting No phase listed Observational
View directory record Official record
Conditions
Substance Use Disorders (SUD), Pregnancy, Maternal Morbidity and Mortality, Cultural Adaptation
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older · Female only
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Dec 23, 2024 · Synced May 22, 2026, 3:50 AM EDT
Active, not recruiting Not applicable Interventional
View directory record Official record
Conditions
Substance Use Disorders, Opioid Use Disorder, Severe, Opioid Use Disorder, Moderate
Interventions
Low Intensity, High Intensity
Other
Lead sponsor
Gavin Bart
Other
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
4
States / cities
Boston, Massachusetts • Minneapolis, Minnesota • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced May 22, 2026, 3:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Substance Use Disorder (SUD)
Interventions
continuing care app
Device
Lead sponsor
Friends Research Institute, Inc.
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced May 22, 2026, 3:50 AM EDT
Recruiting Not applicable Interventional
View directory record Official record
Conditions
Substance Use Disorder
Interventions
Mothering from the Inside Out
Behavioral
Lead sponsor
Baystate Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced May 22, 2026, 3:50 AM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Cannabis Use, Substance Use Disorder (SUD), Healthy
Interventions
Placebo Oral Capsule, THC
Drug
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 21 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced May 22, 2026, 3:50 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Substance Use Disorder (SUD), Drug Overdose, Criminal Behavior
Interventions
Core-interagency community engagement approach, Enhanced-Core plus community engagement specialist
Other
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years and older
Enrollment
1,620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced May 22, 2026, 3:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Smoking Cessation
Interventions
Brief Computer Motivational Interviewing for Smoking Cessation, Nutrition Control
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 19, 2016 · Synced May 22, 2026, 3:50 AM EDT
Completed Phase 2Phase 3 Interventional
View directory record Official record
Conditions
Substance Use Disorder, Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe
Interventions
Extended Release Buprenorphine, Treatment as Usual
Drug
Lead sponsor
Gavin Bart
Other
Eligibility
18 Years and older
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
6
States / cities
New Haven, Connecticut • Baltimore, Maryland • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 8, 2025 · Synced May 22, 2026, 3:50 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Substance Use Disorders
Interventions
Prolonged Exposure Therapy, Cognitive Processing Therapy, Present Centered Therapy
Behavioral
Lead sponsor
Center for Veterans Research and Education
Other
Eligibility
18 Years and older
Enrollment
426 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
14
States / cities
San Diego, California • Tampa, Florida • Atlanta, Georgia + 11 more
Source: ClinicalTrials.gov public record
Updated Jun 24, 2024 · Synced May 22, 2026, 3:50 AM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Adolescent, Depression, Substance Use Disorders
Interventions
Adolescent Coping With Depression/Functional Family Therapy
Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
13 Years to 17 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 11, 2014 · Synced May 22, 2026, 3:50 AM EDT