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Showing 1–24 of 193 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Suicide Risk Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Perceptual Retraining to Reduce Suicide Risk

NCT02845700
View directory record Official record
Conditions
Perceptual Olfactory Bias
Interventions
Perceptual Retraining Treatment, Sham Neutral training
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 60 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Tallahassee, Florida • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Jan 13, 2019 · Synced Jul 23, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Cognitive-Behavioral Therapy for Children With Nightmares as a Mediator of Suicide Risk (COMAA)

NCT05588739
View directory record Official record
Conditions
Nightmare
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
6 Years to 17 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Jul 23, 2026, 2:10 PM EDT
Completed Phase 2 Interventional Results available

Ketamine for Depression and Suicide Risk

NCT02094898
View directory record Official record
Conditions
Depression, Suicide
Interventions
Ketamine
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 10, 2017 · Synced Jul 23, 2026, 2:10 PM EDT
Completed No phase listed Observational

Acoustical Properties of Speech as Indicators of Suicidal Risk

NCT00178906
View directory record Official record
Conditions
Depression
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
25 Years to 65 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 22, 2016 · Synced Jul 23, 2026, 2:10 PM EDT
Active, not recruiting Not applicable Interventional

DBT Skills Groups for Veterans at High Risk for Suicide Attempt

NCT05000749
View directory record Official record
Conditions
Suicide, Attempted
Interventions
DBT-SG, VHA treatment as usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
5
States / cities
San Diego, California • West Haven, Connecticut • Tampa, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Jul 23, 2026, 2:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Public Messaging to Increase Treatment Seeking for Veterans at Risk for Suicide

NCT04784663
View directory record Official record
Conditions
Mental Health, Suicide
Interventions
Messaging, Wait list control
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
355 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Canandaigua, New York
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 23, 2026, 2:10 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Implementation of Suicide Risk Models in Health Systems

NCT06060535
View directory record Official record
Conditions
Suicide, Attempted, Suicide, Fatal
Interventions
Suicide Attempt Risk Model Care Pathway
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
394,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
3
States / cities
Detroit, Michigan • Bloomington, Minnesota • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jul 23, 2026, 2:10 PM EDT
Not yet recruiting Not applicable Interventional

Plan and Protect: Safety Planning for Teens in Rural Emergency Departments

NCT07325474
View directory record Official record
Conditions
Suicide Ideation, Suicide Attempt
Interventions
Plan & Protect safety planning intervention, Care as usual
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 17 Years
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
4
States / cities
Keene, New Hampshire • Lebanon, New Hampshire • New London, New Hampshire
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Jul 23, 2026, 2:10 PM EDT
Completed Not applicable Interventional Results available

Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder: Supplement to COMPUTE 2.0

NCT04939727
View directory record Official record
Conditions
Opioid Use, Opioid-use Disorder, Suicide
Interventions
OUD-CDS + Suicide Risk Model associated CDS
Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 30, 2023 · Synced Jul 23, 2026, 2:10 PM EDT
Recruiting Phase 3 Interventional

Ketamine Treatment of Youth Suicide Attempters

NCT04763343
View directory record Official record
Conditions
Suicide, Attempted
Interventions
Ketamine Hydrochloride, Saline, CAMS Therapy
Drug · Behavioral
Lead sponsor
Tatiana Falcone, MD
Other
Eligibility
14 Years to 30 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 15, 2026 · Synced Jul 23, 2026, 2:10 PM EDT
Recruiting Not applicable Interventional

Scaling up e-Connect in Juvenile Probation Settings

NCT05541926
View directory record Official record
Conditions
Suicide
Interventions
e-Connect
Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
10 Years and older
Enrollment
3,629 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Jul 23, 2026, 2:10 PM EDT
Recruiting Not applicable Interventional

Just-in-time Interventions for Reducing Short-term Suicide Risk

NCT05793541
View directory record Official record
Conditions
Suicide
Interventions
Phone call, Text messaging, Automated interactive smartphone-based tool, Non-interactive pop-up messages
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Jul 23, 2026, 2:10 PM EDT
Completed Phase 2 Interventional Results available

A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide

NCT02133001
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Esketamine, Placebo
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 64 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
14
States / cities
Birmingham, Alabama • San Diego, California • Hartford, Connecticut + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2025 · Synced Jul 23, 2026, 2:10 PM EDT
Recruiting Not applicable Interventional

Augmented Momentary Personal Ecological Risk Evaluation

NCT06704958
View directory record Official record
Conditions
Suicidal Ideation, Self Harm
Interventions
AMPERE EMA app
Other
Lead sponsor
University of Washington
Other
Eligibility
16 Years to 30 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jul 23, 2026, 2:10 PM EDT
Completed Phase 4 Interventional Results available

Effect of Perimenstrual Ovarian Steroid Supplementation on Perimenstrual Suicidality

NCT03720847
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Estradiol Transdermal Patch 0.1 mg/24 hrs, Oral Micronized Progesterone, Inactive Clear Patch, Placebo capsule
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Jul 23, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Improving Cognition Via Exercise in Schizophrenia

NCT03270098
View directory record Official record
Conditions
Schizophrenia and Related Disorders
Interventions
Aerobic Exercise, Stretching and Toning Exercise
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years
Enrollment
104 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
4
States / cities
Stanford, California • Augusta, Georgia • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Jul 23, 2026, 2:10 PM EDT
Completed Not applicable Interventional Results available

Inpatient Cognitive-Behavioral Therapy to Reduce Suicide Risk Post-Discharge

NCT04168645
View directory record Official record
Conditions
Suicide, Attempted
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 15, 2025 · Synced Jul 23, 2026, 2:10 PM EDT
Completed Phase 3 Interventional Results available

54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide

NCT03039192
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Esketamine, Placebo, Standard of Care
Drug · Other
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 64 Years
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
17
States / cities
Birmingham, Alabama • Chandler, Arizona • Garden Grove, California + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 28, 2025 · Synced Jul 23, 2026, 2:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

e-Connect: A Service System Intervention for Justice Youth at Risk for Suicide

NCT03586895
View directory record Official record
Conditions
Suicide
Interventions
e-Connect
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
10 Years and older
Enrollment
12,838 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced Jul 23, 2026, 2:10 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Long-term Observation of Participants With Mood Disorders

NCT04877977
View directory record Official record
Conditions
Depression, Suicide Risk
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 99 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 27, 2025 · Synced Jul 23, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Telehealth to Improve Prevention of Suicide (TIPS)

NCT04800029
View directory record Official record
Conditions
Suicide Risk
Interventions
TIPS Program, TIPS Program + ED-SAFE
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
32,406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Jul 23, 2026, 2:10 PM EDT
Completed No phase listed Observational

A Brief Intervention to Reduce Suicide Risk in Military Service Members and Veterans- Study 1

NCT01334541
View directory record Official record
Conditions
Suicide Risk | Patient
Interventions
SAFE VET
Behavioral
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 89 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
8
States / cities
Long Beach, California • San Diego, California • Denver, Colorado + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 30, 2019 · Synced Jul 23, 2026, 2:10 PM EDT
Completed Not applicable Interventional Results available

Feasibility Trial of a Single Session of Crisis Response Planning for Youth at High Risk for Suicide

NCT06164106
View directory record Official record
Conditions
Suicide Prevention
Interventions
Virtual Crisis Response Planning, In-Person Crisis Response Planning, Crisis Risk Counseling
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
14 Years to 18 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jul 23, 2026, 2:10 PM EDT
Completed Not applicable Interventional

Development of a Positive Psychology Intervention to Reduce Suicide Risk

NCT01398891
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt
Interventions
Positive Psychology Exercises
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 4, 2013 · Synced Jul 23, 2026, 2:10 PM EDT