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ClinicalTrials.gov public records Last synced Oct 28, 2026, 8:01 PM EDT

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Showing 1–24 of 200 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Suicide Risk Clear all
Active, not recruiting Not applicable Interventional

DBT Skills Groups for Veterans at High Risk for Suicide Attempt

NCT05000749
View directory record Official record
Conditions
Suicide, Attempted
Interventions
DBT-SG, VHA treatment as usual
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
156 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
5
States / cities
San Diego, California • West Haven, Connecticut • Tampa, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 28, 2026, 8:01 PM EDT
Completed Not applicable Interventional Results available

Suicide Prevention Intervention for At-Risk Individuals in Transition

NCT02759172
View directory record Official record
Conditions
Suicide
Interventions
Safety Planning Intervention
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Flint, Michigan • Cranston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 28, 2026, 8:01 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Expanding Veteran Sponsorship Initiative+ to Support High-Risk Transitioning Servicemembers and Veterans: A Precision Medicine Approach

NCT07356492
View directory record Official record
Conditions
Reintegration Difficulties, Suicidal Ideation and Behaviors, Health, Connectedness
Interventions
Onward Ops- receive peer sponsor and community support, VA stepped care services
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
2,700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 28, 2026, 8:01 PM EDT
Terminated Not applicable Interventional

Brief Interventions on Social Media to Reduce Suicide Risk (Intervention 1)

NCT06114875
View directory record Official record
Conditions
Distress, Emotional, Suicide
Interventions
Peer support intervention
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
18 Years and older
Enrollment
942 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Oct 28, 2026, 8:01 PM EDT
Completed Not applicable Interventional Results available

A Novel Cognitive Remediation Intervention Targeting Poor Decision-making and Depression in Veterans at High Risk for Suicide: A Safe, Telehealth Approach During the COVID-19 Pandemic

NCT04952532
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Neuropsychological Educational Approach to Cognitive Remediation (NEAR, termed Cognitive Remediation plus Bridging)
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 65 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Oct 28, 2026, 8:01 PM EDT
Suspended Not applicable Interventional

From Hardship to Hope: A Peer-led Intervention to Reduce Financial Hardship and Suicide Risk

NCT04840134
View directory record Official record
Conditions
Suicide, Suicide Ideation, Suicidal Behavior, Hope, Financial Stress
Interventions
From Hardship to Hope: A Peer-led intervention to reduce financial hardship and suicide risk, Enhanced Treatment as Usual (eTAU)
Behavioral · Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 64 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 28, 2026, 8:01 PM EDT
Completed Phase 3 Interventional Results available

54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide

NCT03039192
View directory record Official record
Conditions
Depressive Disorder, Major
Interventions
Esketamine, Placebo, Standard of Care
Drug · Other
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 64 Years
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
17
States / cities
Birmingham, Alabama • Chandler, Arizona • Garden Grove, California + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2025 · Synced Oct 28, 2026, 8:01 PM EDT
Completed No phase listed Observational

A Study to Assess the Validation and Mapping of the Suicide Ideation and Behavior Assessment

NCT03085108
View directory record Official record
Conditions
Suicidality
Interventions
No Intervention
Other
Lead sponsor
Janssen Scientific Affairs, LLC
Industry
Eligibility
12 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
4
States / cities
Birmingham, Alabama • Garden Grove, California • Piscataway, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Oct 28, 2026, 8:01 PM EDT
Active, not recruiting Not applicable Interventional

Motivational Interviewing to Address Suicidal Ideation for Veterans at High Risk for Suicide

NCT05256940
View directory record Official record
Conditions
Suicide, Attempted, Suicidal Ideation
Interventions
Motivational Interviewing to Address Suicidal Ideation- Revised (MI-SI-R), Enhanced usual care (EUC)
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
368 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
3
States / cities
Canandaigua, New York • Portland, Oregon • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Oct 28, 2026, 8:01 PM EDT
Completed Not applicable Interventional Results available

Inpatient Cognitive-Behavioral Therapy to Reduce Suicide Risk Post-Discharge

NCT04168645
View directory record Official record
Conditions
Suicide, Attempted
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Oct 28, 2026, 8:01 PM EDT
Completed No phase listed Observational

Assessing Treatment Emergent Suicidal Ideation in Patients With Major Depression

NCT00532103
View directory record Official record
Conditions
Depression
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 75 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
15
States / cities
Tuscaloosa, Alabama • Harbor City, California • Los Angeles, California + 12 more
Source: ClinicalTrials.gov public record
Updated Sep 22, 2008 · Synced Oct 28, 2026, 8:01 PM EDT
Completed Not applicable Interventional Results available

RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts

NCT03603717
View directory record Official record
Conditions
Insomnia, Suicidal Ideation
Interventions
Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
3
States / cities
Buffalo, New York • Canandaigua, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Oct 28, 2026, 8:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The BE WITH Project: A Partially Nested Randomized Control Trial (PN-RCT)

NCT07204444
View directory record Official record
Conditions
Older Adults, Mental Health, Depression, Loneliness, Social Isolation, Suicide Ideations, Social Functioning, Quality of Life, Thwarted Belongingness, Perceived Burdensomeness, Help-Seeking Behavior, Suicide Risk
Interventions
standardized and manualized warm calls from providers trained in the BE training, standardized and manualized warm calls from providers trained in the BE training + ASIST training
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
55 Years and older
Enrollment
671 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 28, 2026, 8:01 PM EDT
Completed Not applicable Interventional Results available

Crisis Line Facilitation

NCT02459587
View directory record Official record
Conditions
Suicide, Suicide, Attempted, Hospitals, Psychiatric
Interventions
Crisis Line Facilitation (CLF), Enhanced Usual Care (EUC)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 99 Years
Enrollment
307 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Ann Arbor, Michigan • Battle Creek, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 28, 2023 · Synced Oct 28, 2026, 8:01 PM EDT
Not yet recruiting Phase 4 Interventional Accepts healthy volunteers

Teen Vulnerability to Irritability: Brain and Estrogen Changes

NCT07544966
View directory record Official record
Conditions
Depression - Major Depressive Disorder, Irritability
Interventions
Kurvelo, Placebo COC
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
12 Years to 16 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
2
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 28, 2026, 8:01 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

REACH VET Implementation Program Evaluation

NCT03280225
View directory record Official record
Conditions
Suicide
Interventions
External facilitation
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
2
States / cities
North Little Rock, Arkansas • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 25, 2024 · Synced Oct 28, 2026, 8:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trial of Automated Risk Appraisal for Adolescents

NCT00505440
View directory record Official record
Conditions
Substance Use, Depression, Suicidal Ideation, Risk Behavior
Interventions
Telephone case management and motivational interviewing, Usual care
Behavioral
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
11 Years to 20 Years
Enrollment
1,185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 23, 2013 · Synced Oct 28, 2026, 8:01 PM EDT
Not listed Not applicable Interventional

Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder and Borderline Personality Disorder (PTSD-BPD)

NCT04230668
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Borderline Personality Disorder
Interventions
Cognitive Processing Therapy with Suicide Risk Management, Treatment as Usual with Suicide Rick Management
Behavioral
Lead sponsor
Palo Alto University
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Oct 28, 2026, 8:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Navigating Mental Health Treatment for Black Youth

NCT05334381
View directory record Official record
Conditions
Adolescent Behavior, Suicidal Ideation
Interventions
Adapted STAT-ED, Standard Enhanced Treatment As Usual
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
6 Years to 18 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 28, 2026, 8:01 PM EDT
Terminated Phase 2 Interventional Results available

Study of Efficacy and Safety of MIJ821 in Addition to Comprehensive Standard of Care on the Rapid Reduction of Symptoms of Major Depressive Disorder in Subjects Who Have Suicidal Ideation With Intent

NCT04722666
View directory record Official record
Conditions
Major Depressive Disorder With Suicidal Ideation With Intent
Interventions
MIJ821 Intravenous Injection, Placebo Intravenous Injection
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
6
States / cities
Birmingham, Alabama • Farmington, Connecticut • Oakland Park, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 28, 2026, 8:01 PM EDT
Completed Not applicable Interventional

Computerized Anxiety Treatment for Suicide

NCT01990131
View directory record Official record
Conditions
Anxiety, Suicide
Interventions
Cognitive Anxiety Sensitivity Treatment, Physical Health Education Training
Other
Lead sponsor
Florida State University
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Aug 9, 2016 · Synced Oct 28, 2026, 8:01 PM EDT
Completed Not applicable Interventional Results available

Brief Interventions for Short-Term Suicide Risk Reduction in Military Populations

NCT02042131
View directory record Official record
Conditions
Suicide, Suicidal Ideation
Interventions
Treatment As Usual (TAU), Standard Crisis Response Plan (S-CRP), Enhanced Crisis Response Plan (E-CRP)
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 11, 2017 · Synced Oct 28, 2026, 8:01 PM EDT
Recruiting Not applicable Interventional

Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD

NCT07238192
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Suicidal Ideation, Suicide Attempt
Interventions
Cognitive Processing Therapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 28, 2026, 8:01 PM EDT
Completed Phase 2 Interventional Results available

Randomized Trial of Suicide Gene Therapy and Prostate Cancer

NCT00583492
View directory record Official record
Conditions
Prostate Cancer
Interventions
Ad5-yCD/mutTKSR39rep-ADP, IMRT
Biological · Radiation
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Male only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
2
States / cities
Baltimore, Maryland • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 28, 2026, 8:01 PM EDT